Found 252 hits with Last Name = 'lehmann' and Initial = 'f' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM50168761
(3-(1-(4-chlorobenzyl)-5-(2-fluorobiphenyl-4-yl)-3-...)Show SMILES Cc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(cc12)-c1ccc(c(F)c1)-c1ccccc1 Show InChI InChI=1S/C33H29ClFNO2/c1-21-28-17-24(25-11-15-27(29(35)18-25)23-7-5-4-6-8-23)12-16-30(28)36(20-22-9-13-26(34)14-10-22)31(21)19-33(2,3)32(37)38/h4-18H,19-20H2,1-3H3,(H,37,38) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University Tuebingen
Curated by ChEMBL
| Assay Description Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as residual enzyme activity after 1 min by measuring PGE2 level... |
J Med Chem 52: 4968-72 (2009)
Article DOI: 10.1021/jm900481c BindingDB Entry DOI: 10.7270/Q29C6XGX |
More data for this Ligand-Target Pair | |
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM50006805
(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)Show SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c2c1 Show InChI InChI=1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University Tuebingen
Curated by ChEMBL
| Assay Description Binding affinity to FLAP |
J Med Chem 52: 4968-72 (2009)
Article DOI: 10.1021/jm900481c BindingDB Entry DOI: 10.7270/Q29C6XGX |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fatty acid-binding protein, heart
(Homo sapiens (Human)) | BDBM50247996
(5-(2-(trifluoromethyl)benzyl)-5,6,7,8,9,10-hexahyd...)Show SMILES OC(=O)c1cccc2c3CCCCCc3n(Cc3ccccc3C(F)(F)F)c12 Show InChI InChI=1S/C22H20F3NO2/c23-22(24,25)18-11-5-4-7-14(18)13-26-19-12-3-1-2-8-15(19)16-9-6-10-17(20(16)26)21(27)28/h4-7,9-11H,1-3,8,12-13H2,(H,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human H-FABP by scintillation proximity assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247996
(5-(2-(trifluoromethyl)benzyl)-5,6,7,8,9,10-hexahyd...)Show SMILES OC(=O)c1cccc2c3CCCCCc3n(Cc3ccccc3C(F)(F)F)c12 Show InChI InChI=1S/C22H20F3NO2/c23-22(24,25)18-11-5-4-7-14(18)13-26-19-12-3-1-2-8-15(19)16-9-6-10-17(20(16)26)21(27)28/h4-7,9-11H,1-3,8,12-13H2,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by scintillation proximity assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248245
(5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocycloh...)Show SMILES NC(=O)c1cccc(Cn2c3CCCCCc3c3cccc(C(O)=O)c23)c1 Show InChI InChI=1S/C22H22N2O3/c23-21(25)15-7-4-6-14(12-15)13-24-19-11-3-1-2-8-16(19)17-9-5-10-18(20(17)24)22(26)27/h4-7,9-10,12H,1-3,8,11,13H2,(H2,23,25)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by scintillation proximity assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248191
(5-benzyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)Show InChI InChI=1S/C21H21NO2/c23-21(24)18-12-7-11-17-16-10-5-2-6-13-19(16)22(20(17)18)14-15-8-3-1-4-9-15/h1,3-4,7-9,11-12H,2,5-6,10,13-14H2,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by scintillation proximity assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248244
(5-(2-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocycloh...)Show SMILES NC(=O)c1ccccc1Cn1c2CCCCCc2c2cccc(C(O)=O)c12 Show InChI InChI=1S/C22H22N2O3/c23-21(25)15-8-5-4-7-14(15)13-24-19-12-3-1-2-9-16(19)17-10-6-11-18(20(17)24)22(26)27/h4-8,10-11H,1-3,9,12-13H2,(H2,23,25)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by scintillation proximity assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247992
(5-propyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)Show InChI InChI=1S/C17H21NO2/c1-2-11-18-15-10-5-3-4-7-12(15)13-8-6-9-14(16(13)18)17(19)20/h6,8-9H,2-5,7,10-11H2,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248245
(5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocycloh...)Show SMILES NC(=O)c1cccc(Cn2c3CCCCCc3c3cccc(C(O)=O)c23)c1 Show InChI InChI=1S/C22H22N2O3/c23-21(25)15-7-4-6-14(12-15)13-24-19-11-3-1-2-8-16(19)17-9-5-10-18(20(17)24)22(26)27/h4-7,9-10,12H,1-3,8,11,13H2,(H2,23,25)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248196
(9-(3-methoxybenzyl)-2,3,4,9-tetrahydro-1H-carbazol...)Show InChI InChI=1S/C21H21NO3/c1-25-15-7-4-6-14(12-15)13-22-19-11-3-2-8-16(19)17-9-5-10-18(20(17)22)21(23)24/h4-7,9-10,12H,2-3,8,11,13H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152851
(4-(9H-CARBAZOL-9-YL)BUTANOIC ACID | 4-Carbazol-9-y...)Show InChI InChI=1S/C16H15NO2/c18-16(19)10-5-11-17-14-8-3-1-6-12(14)13-7-2-4-9-15(13)17/h1-4,6-9H,5,10-11H2,(H,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247992
(5-propyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)Show InChI InChI=1S/C17H21NO2/c1-2-11-18-15-10-5-3-4-7-12(15)13-8-6-9-14(16(13)18)17(19)20/h6,8-9H,2-5,7,10-11H2,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by scintillation proximity assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247987
(9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxy...)Show InChI InChI=1S/C20H19NO2/c22-20(23)17-11-6-10-16-15-9-4-5-12-18(15)21(19(16)17)13-14-7-2-1-3-8-14/h1-3,6-8,10-11H,4-5,9,12-13H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248191
(5-benzyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)Show InChI InChI=1S/C21H21NO2/c23-21(24)18-12-7-11-17-16-10-5-2-6-13-19(16)22(20(17)18)14-15-8-3-1-4-9-15/h1,3-4,7-9,11-12H,2,5-6,10,13-14H2,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248195
(9-(2-methoxybenzyl)-2,3,4,9-tetrahydro-1H-carbazol...)Show InChI InChI=1S/C21H21NO3/c1-25-19-12-5-2-7-14(19)13-22-18-11-4-3-8-15(18)16-9-6-10-17(20(16)22)21(23)24/h2,5-7,9-10,12H,3-4,8,11,13H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247996
(5-(2-(trifluoromethyl)benzyl)-5,6,7,8,9,10-hexahyd...)Show SMILES OC(=O)c1cccc2c3CCCCCc3n(Cc3ccccc3C(F)(F)F)c12 Show InChI InChI=1S/C22H20F3NO2/c23-22(24,25)18-11-5-4-7-14(18)13-26-19-12-3-1-2-8-15(19)16-9-6-10-17(20(16)26)21(27)28/h4-7,9-11H,1-3,8,12-13H2,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247991
(9-propyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxy...)Show InChI InChI=1S/C16H19NO2/c1-2-10-17-14-9-4-3-6-11(14)12-7-5-8-13(15(12)17)16(18)19/h5,7-8H,2-4,6,9-10H2,1H3,(H,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by scintillation proximity assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, heart
(Homo sapiens (Human)) | BDBM50248238
(9-(2-methylbenzyl)-8-(prop-1-en-2-yl)-2,3,4,9-tetr...)Show InChI InChI=1S/C20H18FNO2/c21-17-10-3-1-6-13(17)12-22-18-11-4-2-7-14(18)15-8-5-9-16(19(15)22)20(23)24/h1,3,5-6,8-10H,2,4,7,11-12H2,(H,23,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human H-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247993
(5-(2-fluorobenzyl)-5,6,7,8,9,10-hexahydrocyclohept...)Show InChI InChI=1S/C21H20FNO2/c22-18-11-5-4-7-14(18)13-23-19-12-3-1-2-8-15(19)16-9-6-10-17(20(16)23)21(24)25/h4-7,9-11H,1-3,8,12-13H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247994
(5-(3-fluorobenzyl)-5,6,7,8,9,10-hexahydrocyclohept...)Show InChI InChI=1S/C21H20FNO2/c22-15-7-4-6-14(12-15)13-23-19-11-3-1-2-8-16(19)17-9-5-10-18(20(17)23)21(24)25/h4-7,9-10,12H,1-3,8,11,13H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247991
(9-propyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxy...)Show InChI InChI=1S/C16H19NO2/c1-2-10-17-14-9-4-3-6-11(14)12-7-5-8-13(15(12)17)16(18)19/h5,7-8H,2-4,6,9-10H2,1H3,(H,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247988
(9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-7-carboxy...)Show InChI InChI=1S/C20H19NO2/c22-20(23)15-10-11-17-16-8-4-5-9-18(16)21(19(17)12-15)13-14-6-2-1-3-7-14/h1-3,6-7,10-12H,4-5,8-9,13H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247995
(5-(4-fluorobenzyl)-5,6,7,8,9,10-hexahydrocyclohept...)Show InChI InChI=1S/C21H20FNO2/c22-15-11-9-14(10-12-15)13-23-19-8-3-1-2-5-16(19)17-6-4-7-18(20(17)23)21(24)25/h4,6-7,9-12H,1-3,5,8,13H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152858
(5-Carbazol-9-yl-pentanoic acid | CHEMBL184795)Show InChI InChI=1S/C17H17NO2/c19-17(20)11-5-6-12-18-15-9-3-1-7-13(15)14-8-2-4-10-16(14)18/h1-4,7-10H,5-6,11-12H2,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248240
(9-(4-fluorobenzyl)-2,3,4,9-tetrahydro-1H-carbazole...)Show InChI InChI=1S/C20H18FNO2/c21-14-10-8-13(9-11-14)12-22-18-7-2-1-4-15(18)16-5-3-6-17(19(16)22)20(23)24/h3,5-6,8-11H,1-2,4,7,12H2,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152850
(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)Show InChI InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247990
(4-benzyl-1,2,3,4-tetrahydrocyclopenta[b]indole-5-c...)Show InChI InChI=1S/C19H17NO2/c21-19(22)16-10-4-9-15-14-8-5-11-17(14)20(18(15)16)12-13-6-2-1-3-7-13/h1-4,6-7,9-10H,5,8,11-12H2,(H,21,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248242
(5-(3-(trifluoromethyl)benzyl)-5,6,7,8,9,10-hexahyd...)Show SMILES OC(=O)c1cccc2c3CCCCCc3n(Cc3cccc(c3)C(F)(F)F)c12 Show InChI InChI=1S/C22H20F3NO2/c23-22(24,25)15-7-4-6-14(12-15)13-26-19-11-3-1-2-8-16(19)17-9-5-10-18(20(17)26)21(27)28/h4-7,9-10,12H,1-3,8,11,13H2,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247970
(9-(4-methylbenzyl)-2,3,4,9-tetrahydro-1H-carbazole...)Show InChI InChI=1S/C21H21NO2/c1-14-9-11-15(12-10-14)13-22-19-8-3-2-5-16(19)17-6-4-7-18(20(17)22)21(23)24/h4,6-7,9-12H,2-3,5,8,13H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152857
(3-(Carbazole-9-sulfonyl)-thiophene-2-carboxylic ac...)Show InChI InChI=1S/C17H11NO4S2/c19-17(20)16-15(9-10-23-16)24(21,22)18-13-7-3-1-5-11(13)12-6-2-4-8-14(12)18/h1-10H,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248246
(5-(1-phenyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol...)Show InChI InChI=1S/C17H18N2O2/c20-17(21)12-5-4-10-15-14-9-6-11-16(14)19(18-15)13-7-2-1-3-8-13/h1-4,7-8,10H,5-6,9,11-12H2,(H,20,21)/b10-4- | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein 5
(Homo sapiens (Human)) | BDBM50152850
(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)Show InChI InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152852
(3-(5-Bromo-indole-1-sulfonyl)-thiophene-2-carboxyl...)Show InChI InChI=1S/C13H8BrNO4S2/c14-9-1-2-10-8(7-9)3-5-15(10)21(18,19)11-4-6-20-12(11)13(16)17/h1-7H,(H,16,17) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152872
(3-(6-Methyl-indole-1-sulfonyl)-thiophene-2-carboxy...)Show InChI InChI=1S/C14H11NO4S2/c1-9-2-3-10-4-6-15(11(10)8-9)21(18,19)12-5-7-20-13(12)14(16)17/h2-8H,1H3,(H,16,17) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152871
(3-(3-Methyl-indole-1-sulfonyl)-thiophene-2-carboxy...)Show InChI InChI=1S/C14H11NO4S2/c1-9-8-15(11-5-3-2-4-10(9)11)21(18,19)12-6-7-20-13(12)14(16)17/h2-8H,1H3,(H,16,17) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247968
(9-(3-(trifluoromethyl)benzyl)-2,3,4,9-tetrahydro-1...)Show SMILES OC(=O)c1cccc2c3CCCCc3n(Cc3cccc(c3)C(F)(F)F)c12 Show InChI InChI=1S/C21H18F3NO2/c22-21(23,24)14-6-3-5-13(11-14)12-25-18-10-2-1-7-15(18)16-8-4-9-17(19(16)25)20(26)27/h3-6,8-9,11H,1-2,7,10,12H2,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, intestinal
(Homo sapiens (Human)) | BDBM50152850
(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)Show InChI InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against intestinal fatty acid binding protein(I-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM50294201
(3-(6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrr...)Show SMILES OC(=O)CCc1c(c(c2CCCn12)-c1ccccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H20ClNO2/c23-17-10-8-16(9-11-17)22-19(12-13-20(25)26)24-14-4-7-18(24)21(22)15-5-2-1-3-6-15/h1-3,5-6,8-11H,4,7,12-14H2,(H,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University Tuebingen
Curated by ChEMBL
| Assay Description Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as residual enzyme activity after 1 min by measuring PGE2 level... |
J Med Chem 52: 4968-72 (2009)
Article DOI: 10.1021/jm900481c BindingDB Entry DOI: 10.7270/Q29C6XGX |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247971
(9-(2-fluoro-6-(trifluoromethyl)benzyl)-2,3,4,9-tet...)Show SMILES OC(=O)c1cccc2c3CCCCc3n(Cc3c(F)cccc3C(F)(F)F)c12 Show InChI InChI=1S/C21H17F4NO2/c22-17-9-4-8-16(21(23,24)25)15(17)11-26-18-10-2-1-5-12(18)13-6-3-7-14(19(13)26)20(27)28/h3-4,6-9H,1-2,5,10-11H2,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248243
(5-(4-(trifluoromethyl)benzyl)-5,6,7,8,9,10-hexahyd...)Show SMILES OC(=O)c1cccc2c3CCCCCc3n(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C22H20F3NO2/c23-22(24,25)15-11-9-14(10-12-15)13-26-19-8-3-1-2-5-16(19)17-6-4-7-18(20(17)26)21(27)28/h4,6-7,9-12H,1-3,5,8,13H2,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM50294202
(2-(6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)CCc1c(c(c2CC(C)(C)Cn12)-c1ccccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C31H31ClN2O3S/c1-21-9-15-25(16-10-21)38(36,37)33-28(35)18-17-26-29(23-11-13-24(32)14-12-23)30(22-7-5-4-6-8-22)27-19-31(2,3)20-34(26)27/h4-16H,17-20H2,1-3H3,(H,33,35) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University Tuebingen
Curated by ChEMBL
| Assay Description Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as residual enzyme activity after 1 min by measuring PGE2 level... |
J Med Chem 52: 4968-72 (2009)
Article DOI: 10.1021/jm900481c BindingDB Entry DOI: 10.7270/Q29C6XGX |
More data for this Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM50006805
(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)Show SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c2c1 Show InChI InChI=1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University Tuebingen
Curated by ChEMBL
| Assay Description Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as residual enzyme activity after 1 min by measuring PGE2 level... |
J Med Chem 52: 4968-72 (2009)
Article DOI: 10.1021/jm900481c BindingDB Entry DOI: 10.7270/Q29C6XGX |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50247969
(9-(4-(trifluoromethyl)benzyl)-2,3,4,9-tetrahydro-1...)Show SMILES OC(=O)c1cccc2c3CCCCc3n(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C21H18F3NO2/c22-21(23,24)14-10-8-13(9-11-14)12-25-18-7-2-1-4-15(18)16-5-3-6-17(19(16)25)20(26)27/h3,5-6,8-11H,1-2,4,7,12H2,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152866
(3-(7-Methoxy-indole-1-sulfonyl)-thiophene-2-carbox...)Show InChI InChI=1S/C14H11NO5S2/c1-20-10-4-2-3-9-5-7-15(12(9)10)22(18,19)11-6-8-21-13(11)14(16)17/h2-8H,1H3,(H,16,17) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152865
(3-(6-Methoxy-indole-1-sulfonyl)-thiophene-2-carbox...)Show InChI InChI=1S/C14H11NO5S2/c1-20-10-3-2-9-4-6-15(11(9)8-10)22(18,19)12-5-7-21-13(12)14(16)17/h2-8H,1H3,(H,16,17) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, heart
(Homo sapiens (Human)) | BDBM50152850
(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)Show InChI InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against heart and muscle fatty acid binding protein(H-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248237
(9-(4-methoxybenzyl)-2,3,4,9-tetrahydro-1H-carbazol...)Show InChI InChI=1S/C21H21NO3/c1-25-15-11-9-14(10-12-15)13-22-19-8-3-2-5-16(19)17-6-4-7-18(20(17)22)21(23)24/h4,6-7,9-12H,2-3,5,8,13H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein 5
(Homo sapiens (Human)) | BDBM50152858
(5-Carbazol-9-yl-pentanoic acid | CHEMBL184795)Show InChI InChI=1S/C17H17NO2/c19-17(20)11-5-6-12-18-15-9-3-1-7-13(15)14-8-2-4-10-16(14)18/h1-4,7-10H,5-6,11-12H2,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50248194
(9-benzyl-4-(hydroxyimino)-2,3,4,9-tetrahydro-1H-ca...)Show InChI InChI=1S/C20H18N2O3/c23-20(24)15-9-4-8-14-18-16(21-25)10-5-11-17(18)22(19(14)15)12-13-6-2-1-3-7-13/h1-4,6-9,16H,5,10-12H2,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description Inhibition of human A-FABP by fluorescence polarization assay |
Bioorg Med Chem Lett 19: 1745-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.084 BindingDB Entry DOI: 10.7270/Q2TX3F8G |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein, adipocyte
(Homo sapiens (Human)) | BDBM50152863
(3-(5-Fluoro-indole-1-sulfonyl)-thiophene-2-carboxy...)Show InChI InChI=1S/C13H8FNO4S2/c14-9-1-2-10-8(7-9)3-5-15(10)21(18,19)11-4-6-20-12(11)13(16)17/h1-7H,(H,16,17) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) |
Bioorg Med Chem Lett 14: 4445-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.057 BindingDB Entry DOI: 10.7270/Q2XD1155 |
More data for this Ligand-Target Pair | |