Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9690 (SCH446211 (SCH6) Analog 23 | tert-butyl N-[(2S)-1-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | -50.5 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9691 (SCH446211 (SCH6) | TERT-BUTYL [(1S)-1-({(1R,2S,5S)...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 3.80 | -48.9 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9684 (2-methylpropyl N-[(2S)-1-[(3aR,4S,6aR)-4-({1-[({[(...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 10 | -46.4 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9689 (SCH446211 (SCH6) Analog 22 | tert-butyl N-[(2S)-1-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 10 | -46.4 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9686 (2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(1R,2S,5S)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 10 | -46.4 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9688 (SCH446211 (SCH6) Analog 21 | tert-butyl N-[(2S)-1-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 14 | -45.6 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9685 (2-methylpropyl N-[(2S)-1-[(1S,3aR,6aS)-1-({1-[({[(...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 15 | -45.4 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087641 (3-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human trypsin. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087645 (4-{2-[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Coagulation factor X | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9687 (2-methylpropyl N-[(2S)-1-[(1R,2S,5S)-2-({1-[({[(S)...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 16 | -45.2 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9683 (2-methylpropyl N-[(2S)-1-[(2S,4R)-4-(tert-butoxy)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 19 | -44.8 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087647 (CHEMBL162277 | [(R)-1-{[((S)-1-Carbamimidoyl-2-hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Coagulation factor X | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087639 ((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Concentration of the compound required for classical fast inhibition of cleavage of the chromogenic substrate by human enzyme Coagulation factor X in... | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9680 (2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(8S)-8-({1-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 26 | -44.0 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9679 (2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(3S)-3-({1-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 26 | -44.0 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9681 (2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(3S)-3-({1-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 28 | -43.8 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9678 (2-methylpropyl N-[(2S)-1-[(2S)-2-{[(2S)-1-[({[(S)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 36 | -43.2 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9682 (2-methylpropyl N-[(1S)-2-[(2S,4R)-4-(tert-butylsul...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 120 | -40.2 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9677 (2-methylpropyl N-[(2S)-1-[(2S,4R)-2-({1-[({[(S)-(d...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 140 | -39.8 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H)) | BDBM9676 (2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(2S)-2-({1-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+4 | -29.0 | n/a | n/a | n/a | n/a | n/a | 6.5 | 30 |
Schering-Plough Research Institute | Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I... | J Med Chem 49: 2750-7 (2006) Article DOI: 10.1021/jm060077j BindingDB Entry DOI: 10.7270/Q2V98691 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50044862 (2-(2-Benzyl-5-cyano-4-oxo-pentanoylamino)-3-phenyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Biotechnology/Industrial Associates Curated by ChEMBL | Assay Description Inhibition constant determined for neutral endopeptidase (NEP) | J Med Chem 36: 2408-11 (1993) BindingDB Entry DOI: 10.7270/Q26D5S2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50044861 (2-[2-(2-Cyano-acetylamino)-3-phenyl-propionylamino...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Biotechnology/Industrial Associates Curated by ChEMBL | Assay Description Inhibition constant determined for Neutral endopeptidase (NEP) | J Med Chem 36: 2408-11 (1993) BindingDB Entry DOI: 10.7270/Q26D5S2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50044861 (2-[2-(2-Cyano-acetylamino)-3-phenyl-propionylamino...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Biotechnology/Industrial Associates Curated by ChEMBL | Assay Description Inhibition constant determined for Angiotensin I converting enzyme | J Med Chem 36: 2408-11 (1993) BindingDB Entry DOI: 10.7270/Q26D5S2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50044862 (2-(2-Benzyl-5-cyano-4-oxo-pentanoylamino)-3-phenyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Biotechnology/Industrial Associates Curated by ChEMBL | Assay Description Inhibition constant determined for angiotensin converting enzyme (ACE) | J Med Chem 36: 2408-11 (1993) BindingDB Entry DOI: 10.7270/Q26D5S2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50054486 (CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a. | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50083743 (1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Factor Xa. | Bioorg Med Chem Lett 9: 3459-64 (2000) BindingDB Entry DOI: 10.7270/Q2JD4W1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50054484 (CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a. | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50093056 ((S)-N-Benzo[1,3]dioxol-5-ylmethyl-4-cyclohexyl-3-{...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Coagulation factor X | Bioorg Med Chem Lett 10: 2305-9 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VBR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087644 ((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50093057 ((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Coagulation factor X | Bioorg Med Chem Lett 10: 2305-9 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VBR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087635 (((R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibition of human VCAM and Ramos cell VLA-4 interaction | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087635 (((R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087635 (((R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibition of human VCAM and Ramos cell VLA-4 interaction | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087638 ((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087636 ((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087636 ((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibition of human VCAM and Ramos cell VLA-4 interaction | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087643 (2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087642 (CHEMBL163251 | N-[((S)-1-Carbamimidoyl-2-hydroxy-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anionic trypsin (Bos taurus) | BDBM50054482 ((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsin | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50054482 ((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a. | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087640 (2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.37 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISA | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087640 (2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50054483 ((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a. | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50054483 ((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a. | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50054487 (CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a. | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50054487 (CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International Inc. Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a. | J Med Chem 39: 4527-30 (1996) Article DOI: 10.1021/jm960607j BindingDB Entry DOI: 10.7270/Q2CR5SFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50093062 ((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Coagulation factor X | Bioorg Med Chem Lett 10: 2305-9 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VBR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50093066 (((S)-4-Cyclohexyl-3-{2-[((R)-5-guanidino-2-phenylm...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Coagulation factor X | Bioorg Med Chem Lett 10: 2305-9 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VBR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087637 (2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISA | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50087637 (2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 745-9 (2000) BindingDB Entry DOI: 10.7270/Q2D50M5R | |||||||||||
More data for this Ligand-Target Pair |
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