Compile Data Set for Download or QSAR

Found 180 hits with Last Name = 'linget' and Initial = 'jm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306222 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-f...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H25Cl2FN4O3/c30-20-9-5-18(6-10-20)27-22(17-25(33)37)26(34-36(27)24-4-2-1-3-23(24)31)28(38)35-15-13-29(39,14-16-35)19-7-11-21(32)12-8-19/h1-12,39H,13-17H2,(H2,33,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306234 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-cyan...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)(C#N)c1ccccc1 Show InChI InChI=1S/C30H25Cl2N5O2/c31-22-12-10-20(11-13-22)28-23(18-26(34)38)27(35-37(28)25-9-5-4-8-24(25)32)29(39)36-16-14-30(19-33,15-17-36)21-6-2-1-3-7-21/h1-13H,14-18H2,(H2,34,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306235 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccccc1 Show InChI InChI=1S/C29H26Cl2N4O3/c30-21-12-10-19(11-13-21)27-22(18-25(32)36)26(33-35(27)24-9-5-4-8-23(24)31)28(37)34-16-14-29(38,15-17-34)20-6-2-1-3-7-20/h1-13,38H,14-18H2,(H2,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306222 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-f...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H25Cl2FN4O3/c30-20-9-5-18(6-10-20)27-22(17-25(33)37)26(34-36(27)24-4-2-1-3-23(24)31)28(38)35-15-13-29(39,14-16-35)19-7-11-21(32)12-8-19/h1-12,39H,13-17H2,(H2,33,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306234 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-cyan...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)(C#N)c1ccccc1 Show InChI InChI=1S/C30H25Cl2N5O2/c31-22-12-10-20(11-13-22)28-23(18-26(34)38)27(35-37(28)25-9-5-4-8-24(25)32)29(39)36-16-14-30(19-33,15-17-36)21-6-2-1-3-7-21/h1-13H,14-18H2,(H2,34,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306235 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccccc1 Show InChI InChI=1S/C29H26Cl2N4O3/c30-21-12-10-19(11-13-21)27-22(18-25(32)36)26(33-35(27)24-9-5-4-8-23(24)31)28(37)34-16-14-29(38,15-17-34)20-6-2-1-3-7-20/h1-13,38H,14-18H2,(H2,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306225 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)c1ncccn1 Show InChI InChI=1S/C27H24Cl2N6O2/c28-19-8-6-17(7-9-19)25-20(16-23(30)36)24(33-35(25)22-5-2-1-4-21(22)29)27(37)34-14-10-18(11-15-34)26-31-12-3-13-32-26/h1-9,12-13,18H,10-11,14-16H2,(H2,30,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306232 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NCC1CCN(CC1)C#N Show InChI InChI=1S/C25H24Cl2N6O2/c26-18-7-5-17(6-8-18)24-19(13-22(29)34)23(31-33(24)21-4-2-1-3-20(21)27)25(35)30-14-16-9-11-32(15-28)12-10-16/h1-8,16H,9-14H2,(H2,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in COS7 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306215 (4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-c...) Show SMILES NC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H24Cl2N6O/c24-16-10-8-15(9-11-16)22-17(14-20(26)27)21(23(32)29-30-12-4-1-5-13-30)28-31(22)19-7-3-2-6-18(19)25/h2-3,6-11H,1,4-5,12-14H2,(H3,26,27)(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306232 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NCC1CCN(CC1)C#N Show InChI InChI=1S/C25H24Cl2N6O2/c26-18-7-5-17(6-8-18)24-19(13-22(29)34)23(31-33(24)21-4-2-1-3-20(21)27)25(35)30-14-16-9-11-32(15-28)12-10-16/h1-8,16H,9-14H2,(H2,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306220 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(2-f...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)c1ccccc1F Show InChI InChI=1S/C29H25Cl2FN4O2/c30-20-11-9-19(10-12-20)28-22(17-26(33)37)27(34-36(28)25-8-4-2-6-23(25)31)29(38)35-15-13-18(14-16-35)21-5-1-3-7-24(21)32/h1-12,18H,13-17H2,(H2,33,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306221 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(2-f...) Show SMILES ONC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)c1ccccc1F Show InChI InChI=1S/C29H26Cl2FN5O2/c30-20-11-9-19(10-12-20)28-22(17-26(33)35-39)27(34-37(28)25-8-4-2-6-23(25)31)29(38)36-15-13-18(14-16-36)21-5-1-3-7-24(21)32/h1-12,18,39H,13-17H2,(H2,33,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306231 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES Cc1ccncc1NC(=O)c1nn(c(c1CC(N)=O)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C24H19Cl2N5O2/c1-14-10-11-28-13-19(14)29-24(33)22-17(12-21(27)32)23(15-6-8-16(25)9-7-15)31(30-22)20-5-3-2-4-18(20)26/h2-11,13H,12H2,1H3,(H2,27,32)(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306226 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyr...) Show SMILES NC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)c1ncccn1 Show InChI InChI=1S/C27H25Cl2N7O/c28-19-8-6-17(7-9-19)25-20(16-23(30)31)24(34-36(25)22-5-2-1-4-21(22)29)27(37)35-14-10-18(11-15-35)26-32-12-3-13-33-26/h1-9,12-13,18H,10-11,14-16H2,(H3,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306232 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NCC1CCN(CC1)C#N Show InChI InChI=1S/C25H24Cl2N6O2/c26-18-7-5-17(6-8-18)24-19(13-22(29)34)23(31-33(24)21-4-2-1-3-20(21)27)25(35)30-14-16-9-11-32(15-28)12-10-16/h1-8,16H,9-14H2,(H2,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306225 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)c1ncccn1 Show InChI InChI=1S/C27H24Cl2N6O2/c28-19-8-6-17(7-9-19)25-20(16-23(30)36)24(33-35(25)22-5-2-1-4-21(22)29)27(37)34-14-10-18(11-15-34)26-31-12-3-13-32-26/h1-9,12-13,18H,10-11,14-16H2,(H2,30,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306234 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-cyan...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)(C#N)c1ccccc1 Show InChI InChI=1S/C30H25Cl2N5O2/c31-22-12-10-20(11-13-22)28-23(18-26(34)38)27(35-37(28)25-9-5-4-8-24(25)32)29(39)36-16-14-30(19-33,15-17-36)21-6-2-1-3-7-21/h1-13H,14-18H2,(H2,34,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306230 (4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-c...) Show SMILES NC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C25H20Cl2FN5O/c26-17-9-7-16(8-10-17)24-19(13-22(29)30)23(32-33(24)21-4-2-1-3-20(21)27)25(34)31-14-15-5-11-18(28)12-6-15/h1-12H,13-14H2,(H3,29,30)(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306214 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H23Cl2N5O2/c24-16-10-8-15(9-11-16)22-17(14-20(26)31)21(23(32)28-29-12-4-1-5-13-29)27-30(22)19-7-3-2-6-18(19)25/h2-3,6-11H,1,4-5,12-14H2,(H2,26,31)(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306215 (4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-c...) Show SMILES NC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H24Cl2N6O/c24-16-10-8-15(9-11-16)22-17(14-20(26)27)21(23(32)29-30-12-4-1-5-13-30)28-31(22)19-7-3-2-6-18(19)25/h2-3,6-11H,1,4-5,12-14H2,(H3,26,27)(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.930	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306229 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-fluorop...) Show SMILES ONC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C24H18Cl2FN5O2/c25-15-7-5-14(6-8-15)23-18(13-21(28)31-34)22(24(33)29-17-11-9-16(27)10-12-17)30-32(23)20-4-2-1-3-19(20)26/h1-12,34H,13H2,(H2,28,31)(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306239 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NC1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C27H27Cl2N5O3/c28-18-9-7-16(8-10-18)25-20(15-23(30)35)24(32-34(25)22-4-2-1-3-21(22)29)26(36)31-19-11-13-33(14-12-19)27(37)17-5-6-17/h1-4,7-10,17,19H,5-6,11-15H2,(H2,30,35)(H,31,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306233 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(5-c...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCN(CC1)c1ccc(cn1)C#N Show InChI InChI=1S/C28H23Cl2N7O2/c29-20-8-6-19(7-9-20)27-21(15-24(32)38)26(34-37(27)23-4-2-1-3-22(23)30)28(39)36-13-11-35(12-14-36)25-10-5-18(16-31)17-33-25/h1-10,17H,11-15H2,(H2,32,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306230 (4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-c...) Show SMILES NC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C25H20Cl2FN5O/c26-17-9-7-16(8-10-17)24-19(13-22(29)30)23(32-33(24)21-4-2-1-3-20(21)27)25(34)31-14-15-5-11-18(28)12-6-15/h1-12H,13-14H2,(H3,29,30)(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306216 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(2-(hydrox...) Show SMILES ONC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H24Cl2N6O2/c24-16-10-8-15(9-11-16)22-17(14-20(26)29-33)21(23(32)28-30-12-4-1-5-13-30)27-31(22)19-7-3-2-6-18(19)25/h2-3,6-11,33H,1,4-5,12-14H2,(H2,26,29)(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306225 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(CC1)c1ncccn1 Show InChI InChI=1S/C27H24Cl2N6O2/c28-19-8-6-17(7-9-19)25-20(16-23(30)36)24(33-35(25)22-5-2-1-4-21(22)29)27(37)34-14-10-18(11-15-34)26-31-12-3-13-32-26/h1-9,12-13,18H,10-11,14-16H2,(H2,30,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306233 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(5-c...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCN(CC1)c1ccc(cn1)C#N Show InChI InChI=1S/C28H23Cl2N7O2/c29-20-8-6-19(7-9-20)27-21(15-24(32)38)26(34-37(27)23-4-2-1-3-22(23)30)28(39)36-13-11-35(12-14-36)25-10-5-18(16-31)17-33-25/h1-10,17H,11-15H2,(H2,32,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306214 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H23Cl2N5O2/c24-16-10-8-15(9-11-16)22-17(14-20(26)31)21(23(32)28-29-12-4-1-5-13-29)27-30(22)19-7-3-2-6-18(19)25/h2-3,6-11H,1,4-5,12-14H2,(H2,26,31)(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306228 (4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-c...) Show SMILES NC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C24H18Cl2FN5O/c25-15-7-5-14(6-8-15)23-18(13-21(28)29)22(24(33)30-17-11-9-16(27)10-12-17)31-32(23)20-4-2-1-3-19(20)26/h1-12H,13H2,(H3,28,29)(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306231 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES Cc1ccncc1NC(=O)c1nn(c(c1CC(N)=O)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C24H19Cl2N5O2/c1-14-10-11-28-13-19(14)29-24(33)22-17(12-21(27)32)23(15-6-8-16(25)9-7-15)31(30-22)20-5-3-2-4-18(20)26/h2-11,13H,12H2,1H3,(H2,27,32)(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306217 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCOCC1 Show InChI InChI=1S/C22H21Cl2N5O3/c23-15-7-5-14(6-8-15)21-16(13-19(25)30)20(22(31)27-28-9-11-32-12-10-28)26-29(21)18-4-2-1-3-17(18)24/h1-8H,9-13H2,(H2,25,30)(H,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306214 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H23Cl2N5O2/c24-16-10-8-15(9-11-16)22-17(14-20(26)31)21(23(32)28-29-12-4-1-5-13-29)27-30(22)19-7-3-2-6-18(19)25/h2-3,6-11H,1,4-5,12-14H2,(H2,26,31)(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306216 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(2-(hydrox...) Show SMILES ONC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H24Cl2N6O2/c24-16-10-8-15(9-11-16)22-17(14-20(26)29-33)21(23(32)28-30-12-4-1-5-13-30)27-31(22)19-7-3-2-6-18(19)25/h2-3,6-11,33H,1,4-5,12-14H2,(H2,26,29)(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305420 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...) Show SMILES Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C23H21Cl2N5O/c24-17-10-8-16(9-11-17)22-18(12-13-26)21(23(31)28-29-14-4-1-5-15-29)27-30(22)20-7-3-2-6-19(20)25/h2-3,6-11H,1,4-5,12,14-15H2,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306223 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-f...) Show SMILES NC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H26Cl2FN5O2/c30-20-9-5-18(6-10-20)27-22(17-25(33)34)26(35-37(27)24-4-2-1-3-23(24)31)28(38)36-15-13-29(39,14-16-36)19-7-11-21(32)12-8-19/h1-12,39H,13-17H2,(H3,33,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306236 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccccn1 Show InChI InChI=1S/C28H25Cl2N5O3/c29-19-10-8-18(9-11-19)26-20(17-24(31)36)25(33-35(26)22-6-2-1-5-21(22)30)27(37)34-15-12-28(38,13-16-34)23-7-3-4-14-32-23/h1-11,14,38H,12-13,15-17H2,(H2,31,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306236 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccccn1 Show InChI InChI=1S/C28H25Cl2N5O3/c29-19-10-8-18(9-11-19)26-20(17-24(31)36)25(33-35(26)22-6-2-1-5-21(22)30)27(37)34-15-12-28(38,13-16-34)23-7-3-4-14-32-23/h1-11,14,38H,12-13,15-17H2,(H2,31,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305395 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...) Show SMILES Fc1ccc(CNC(=O)c2nn(c(c2CC#N)-c2ccc(Cl)cc2)-c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H17Cl2FN4O/c26-18-9-7-17(8-10-18)24-20(13-14-29)23(31-32(24)22-4-2-1-3-21(22)27)25(33)30-15-16-5-11-19(28)12-6-16/h1-12H,13,15H2,(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306240 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(5-f...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccc(F)cn1 Show InChI InChI=1S/C28H24Cl2FN5O3/c29-18-7-5-17(6-8-18)26-20(15-24(32)37)25(34-36(26)22-4-2-1-3-21(22)30)27(38)35-13-11-28(39,12-14-35)23-10-9-19(31)16-33-23/h1-10,16,39H,11-15H2,(H2,32,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306222 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-f...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H25Cl2FN4O3/c30-20-9-5-18(6-10-20)27-22(17-25(33)37)26(34-36(27)24-4-2-1-3-23(24)31)28(38)35-15-13-29(39,14-16-35)19-7-11-21(32)12-8-19/h1-12,39H,13-17H2,(H2,33,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306235 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccccc1 Show InChI InChI=1S/C29H26Cl2N4O3/c30-21-12-10-19(11-13-21)27-22(18-25(32)36)26(33-35(27)24-9-5-4-8-23(24)31)28(37)34-16-14-29(38,15-17-34)20-6-2-1-3-7-20/h1-13,38H,14-18H2,(H2,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in COS7 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306231 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES Cc1ccncc1NC(=O)c1nn(c(c1CC(N)=O)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C24H19Cl2N5O2/c1-14-10-11-28-13-19(14)29-24(33)22-17(12-21(27)32)23(15-6-8-16(25)9-7-15)31(30-22)20-5-3-2-4-18(20)26/h2-11,13H,12H2,1H3,(H2,27,32)(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305435 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-f...) Show SMILES OC1(CCN(CC1)C(=O)c1nn(c(c1CC#N)-c1ccc(Cl)cc1)-c1ccccc1Cl)c1ccc(F)cc1 Show InChI InChI=1S/C29H23Cl2FN4O2/c30-21-9-5-19(6-10-21)27-23(13-16-33)26(34-36(27)25-4-2-1-3-24(25)31)28(37)35-17-14-29(38,15-18-35)20-7-11-22(32)12-8-20/h1-12,38H,13-15,17-18H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50134148 ((5R,6R)-6-Benzo[1,3]dioxol-5-yl-2-butyl-2,3,6,7,12...) Show SMILES CCCCN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O Show InChI InChI=1S/C25H25N3O4/c1-2-3-10-27-13-22(29)28-19(25(27)30)12-17-16-6-4-5-7-18(16)26-23(17)24(28)15-8-9-20-21(11-15)32-14-31-20/h4-9,11,19,24,26H,2-3,10,12-14H2,1H3/t19-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description In vitro inhibitory activity against bovine phosphodiesterase 5				J Med Chem 46: 4533-42 (2003) Article DOI: 10.1021/jm0300577 BindingDB Entry DOI: 10.7270/Q2N015X2
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50134125 ((5R,6R)-6-Benzo[1,3]dioxol-5-yl-2-benzyl-2,3,6,7,1...) Show SMILES O=C1CN(Cc2ccccc2)C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@H](N12)c1ccc2OCOc2c1 Show InChI InChI=1S/C28H23N3O4/c32-25-15-30(14-17-6-2-1-3-7-17)28(33)22-13-20-19-8-4-5-9-21(19)29-26(20)27(31(22)25)18-10-11-23-24(12-18)35-16-34-23/h1-12,22,27,29H,13-16H2/t22-,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description In vitro inhibitory activity against bovine phosphodiesterase 5				J Med Chem 46: 4533-42 (2003) Article DOI: 10.1021/jm0300577 BindingDB Entry DOI: 10.7270/Q2N015X2
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50134148 ((5R,6R)-6-Benzo[1,3]dioxol-5-yl-2-butyl-2,3,6,7,12...) Show SMILES CCCCN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O Show InChI InChI=1S/C25H25N3O4/c1-2-3-10-27-13-22(29)28-19(25(27)30)12-17-16-6-4-5-7-18(16)26-23(17)24(28)15-8-9-20-21(11-15)32-14-31-20/h4-9,11,19,24,26H,2-3,10,12-14H2,1H3/t19-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description In vitro inhibitory activity against bovine phosphodiesterase 5				J Med Chem 46: 4533-42 (2003) Article DOI: 10.1021/jm0300577 BindingDB Entry DOI: 10.7270/Q2N015X2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306236 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydr...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)N1CCC(O)(CC1)c1ccccn1 Show InChI InChI=1S/C28H25Cl2N5O3/c29-19-10-8-18(9-11-19)26-20(17-24(31)36)25(33-35(26)22-6-2-1-5-21(22)30)27(37)34-15-12-28(38,13-16-34)23-7-3-4-14-32-23/h1-11,14,38H,12-13,15-17H2,(H2,31,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306239 (4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...) Show SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NC1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C27H27Cl2N5O3/c28-18-9-7-16(8-10-18)25-20(15-23(30)35)24(32-34(25)22-4-2-1-3-21(22)29)26(36)31-19-11-13-33(14-12-19)27(37)17-5-6-17/h1-4,7-10,17,19H,5-6,11-15H2,(H2,30,35)(H,31,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50306224 (2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyr...) Show SMILES Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)N1CCC(CC1)c1ncccn1 Show InChI InChI=1S/C27H22Cl2N6O/c28-20-8-6-18(7-9-20)25-21(10-13-30)24(33-35(25)23-5-2-1-4-22(23)29)27(36)34-16-11-19(12-17-34)26-31-14-3-15-32-26/h1-9,14-15,19H,10-12,16-17H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS binding				Bioorg Med Chem Lett 20: 453-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.003 BindingDB Entry DOI: 10.7270/Q2MK6D09
					More data for this Ligand-Target Pair

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