Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50061306 ((3S,4aS,8aS)-2-[(2R,3R)-2-Hydroxy-3-(3-hydroxy-2-m...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 protease | J Med Chem 40: 3979-85 (1998) Article DOI: 10.1021/jm9704098 BindingDB Entry DOI: 10.7270/Q2V69K71 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50061307 (AG-1254 | CHEMBL128696 | N-[(1R,2R)-3-(2-tert-Buty...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 protease | J Med Chem 40: 3979-85 (1998) Article DOI: 10.1021/jm9704098 BindingDB Entry DOI: 10.7270/Q2V69K71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50061308 ((3S,4aS,8aS)-2-[(2R,3S)-2-Hydroxy-3-(3-hydroxy-2-m...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 protease | J Med Chem 40: 3979-85 (1998) Article DOI: 10.1021/jm9704098 BindingDB Entry DOI: 10.7270/Q2V69K71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50061305 ((3S,4aS,8aS)-2-[(2R,3R)-2-Hydroxy-3-(3-hydroxy-2-m...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 protease | J Med Chem 40: 3979-85 (1998) Article DOI: 10.1021/jm9704098 BindingDB Entry DOI: 10.7270/Q2V69K71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM3414 ((2S)-N-[(2S,3R)-4-[2-(tert-butylcarbamoyl)phenyl]-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM519 ((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50286697 (CHEMBL347662 | N-[(1S,2R)-1-Benzyl-3-(2-tert-butyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50286694 (CHEMBL163243 | N*3*-[(1S,2R)-1-Benzyl-3-((3S,4aS,8...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50213828 (CHEMBL3706748) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50286698 (1N-(tert-butyl)-2-[2-hydroxy-4-phenyl-3-[3-(1,2,3,...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50286693 (CHEMBL163563 | N-[(1S,2R)-1-Benzyl-3-(2-tert-butyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50286692 (CHEMBL163616 | N-[(1S,2R)-1-Benzyl-3-(2-tert-butyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50286696 (CHEMBL351680 | N-[(1S,2R)-1-Benzyl-3-(2-tert-butyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against human immunodeficiency virus protease (HIVP) using protease inhibition assay | Bioorg Med Chem Lett 5: 721-726 (1995) Article DOI: 10.1016/0960-894X(95)00102-Y BindingDB Entry DOI: 10.7270/Q2FJ2GRK | |||||||||||
More data for this Ligand-Target Pair |