Compile Data Set for Download or QSAR

Found 82 hits with Last Name = 'lucas' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Rattus norvegicus (Rat))	BDBM50024094 ((R,S) 2-(2-Mercaptomethyl-3-phenyl-propionylamino)...) Show SMILES C[C@@H](NC(=O)[C@H](CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C13H17NO3S/c1-9(13(16)17)14-12(15)11(8-18)7-10-5-3-2-4-6-10/h2-6,9,11,18H,7-8H2,1H3,(H,14,15)(H,16,17)/t9-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50024101 ((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...) Show SMILES C[C@H](NC(=O)[C@@H](CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C13H17NO3S/c1-9(13(16)17)14-12(15)11(8-18)7-10-5-3-2-4-6-10/h2-6,9,11,18H,7-8H2,1H3,(H,14,15)(H,16,17)/t9-,11+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50024100 ((R,S) N-(1-Mercaptomethyl-2-phenyl-ethyl)-2-methyl...) Show SMILES C[C@@H](C(O)=O)C(=O)N[C@H](CS)Cc1ccccc1 Show InChI InChI=1S/C13H17NO3S/c1-9(13(16)17)12(15)14-11(8-18)7-10-5-3-2-4-6-10/h2-6,9,11,18H,7-8H2,1H3,(H,14,15)(H,16,17)/t9-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50024097 ((R,R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-2-methyl...) Show SMILES C[C@H](C(O)=O)C(=O)N[C@H](CS)Cc1ccccc1 Show InChI InChI=1S/C13H17NO3S/c1-9(13(16)17)12(15)14-11(8-18)7-10-5-3-2-4-6-10/h2-6,9,11,18H,7-8H2,1H3,(H,14,15)(H,16,17)/t9-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50024098 ((R,R) 2-(1-Mercaptomethyl-2-phenyl-ethylcarbamoyl)...) Show SMILES CC(C)C[C@H](C(O)=O)C(=O)N[C@H](CS)Cc1ccccc1 Show InChI InChI=1S/C16H23NO3S/c1-11(2)8-14(16(19)20)15(18)17-13(10-21)9-12-6-4-3-5-7-12/h3-7,11,13-14,21H,8-10H2,1-2H3,(H,17,18)(H,19,20)/t13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50002022 ((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H16N2O5/c16-11(15-20)7-10(13(19)14-8-12(17)18)6-9-4-2-1-3-5-9/h1-5,10,20H,6-8H2,(H,14,19)(H,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory potency against neutral endopeptidase				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50024099 ((R,S) 2-(1-Mercaptomethyl-2-phenyl-ethylcarbamoyl)...) Show SMILES CC(C)C[C@@H](C(O)=O)C(=O)N[C@H](CS)Cc1ccccc1 Show InChI InChI=1S/C16H23NO3S/c1-11(2)8-14(16(19)20)15(18)17-13(10-21)9-12-6-4-3-5-7-12/h3-7,11,13-14,21H,8-10H2,1-2H3,(H,17,18)(H,19,20)/t13-,14+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50024096 (((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...) Show SMILES OC(=O)CNC(=O)[C@H](CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50024102 (((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...) Show SMILES OC(=O)CNC(=O)[C@@H](CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neprilysin (Rattus norvegicus (Rat))	BDBM50024095 ((R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic ...) Show SMILES OC(=O)CC(=O)N[C@H](CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(7-12(15)16)13-10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,14)(H,15,16)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50406747 (CHEMBL2110347) Show SMILES CC(C)C[C@H](S)[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(O)=O Show InChI InChI=1S/C17H25NO3S/c1-11(2)9-15(22)14(10-13-7-5-4-6-8-13)16(19)18-12(3)17(20)21/h4-8,11-12,14-15,22H,9-10H2,1-3H3,(H,18,19)(H,20,21)/t12-,14+,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM21641 (2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...) Show SMILES OC(=O)CNC(=O)C(CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neprilysin (Homo sapiens (Human))	BDBM50002018 (2-(2-Mercaptomethyl-3-phenyl-propionylamino)-4-met...) Show SMILES CC(C)C[C@@H](NC(=O)C(CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H23NO3S/c1-11(2)8-14(16(19)20)17-15(18)13(10-21)9-12-6-4-3-5-7-12/h3-7,11,13-14,21H,8-10H2,1-2H3,(H,17,18)(H,19,20)/t13?,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory potency against neutral endopeptidase				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002031 (1-Mercaptomethyl-3-methylsulfanyl-propyl-ammonium) Show SMILES CSCCC([NH3+])CS Show InChI InChI=1S/C5H13NS2/c1-8-3-2-5(6)4-7/h5,7H,2-4,6H2,1H3/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50038623 (2-(2-Benzyl-3-mercapto-5-methyl-hexanoylamino)-pro...) Show SMILES CC(C)CC(S)C(Cc1ccccc1)C(=O)NC(C)C(O)=O Show InChI InChI=1S/C17H25NO3S/c1-11(2)9-15(22)14(10-13-7-5-4-6-8-13)16(19)18-12(3)17(20)21/h4-8,11-12,14-15,22H,9-10H2,1-3H3,(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50002035 ((2-Hydroxycarbamoyl-3-phenyl-propionylamino)-aceti...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C12H14N2O5/c15-10(16)7-13-11(17)9(12(18)14-19)6-8-4-2-1-3-5-8/h1-5,9,19H,6-7H2,(H,13,17)(H,14,18)(H,15,16)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory potency against neutral endopeptidase				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002026 (2-Mercapto-1-methylsulfanylmethyl-ethyl-ammonium) Show SMILES CSCC([NH3+])CS Show InChI InChI=1S/C4H11NS2/c1-7-3-4(5)2-6/h4,6H,2-3,5H2,1H3/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046267 ((RRS) 2-(2-Benzyl-3-mercapto-5-methyl-hexanoylamin...) Show SMILES CC(C)C[C@@H](S)[C@H](Cc1ccccc1)C(=O)N[C@@H](C)C(O)=O Show InChI InChI=1S/C17H25NO3S/c1-11(2)9-15(22)14(10-13-7-5-4-6-8-13)16(19)18-12(3)17(20)21/h4-8,11-12,14-15,22H,9-10H2,1-3H3,(H,18,19)(H,20,21)/t12-,14-,15+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50368599 (CHEMBL1159809) Show SMILES CS(=O)CCC(N)CS Show InChI InChI=1S/C5H13NOS2/c1-9(7)3-2-5(6)4-8/h5,8H,2-4,6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50368598 (CHEMBL1159810) Show SMILES CS(=O)CC(N)CS Show InChI InChI=1S/C4H11NOS2/c1-8(6)3-4(5)2-7/h4,7H,2-3,5H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002027 (1-Mercaptomethyl-3-methyl-butyl-ammonium) Show SMILES CC(C)CC([NH3+])CS Show InChI InChI=1S/C6H15NS/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002034 (2-Mercapto-1-phenyl-ethyl-ammonium) Show SMILES [NH3+]C(CS)c1ccccc1 Show InChI InChI=1S/C8H11NS/c9-8(6-10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrate				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046256 (2-(2-Benzyl-3-mercapto-5-methyl-hexanoylamino)-3-(...) Show SMILES CC(C)CC(S)C(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C23H29NO4S/c1-15(2)12-21(29)19(13-16-6-4-3-5-7-16)22(26)24-20(23(27)28)14-17-8-10-18(25)11-9-17/h3-11,15,19-21,25,29H,12-14H2,1-2H3,(H,24,26)(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50036828 (1-Mercaptomethyl-2-phenyl-ethyl-ammonium | 2-Amino...) Show SMILES NC(CS)Cc1ccccc1 Show InChI InChI=1S/C9H13NS/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrate				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50406748 (CHEMBL2110258) Show SMILES CC(C)C[C@H](S)[C@H](Cc1ccccc1)C(=O)N[C@@H](C)C(O)=O Show InChI InChI=1S/C17H25NO3S/c1-11(2)9-15(22)14(10-13-7-5-4-6-8-13)16(19)18-12(3)17(20)21/h4-8,11-12,14-15,22H,9-10H2,1-3H3,(H,18,19)(H,20,21)/t12-,14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046261 (2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...) Show SMILES CC(C)CC(S)CC(=O)NC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H23NO3S/c1-11(2)8-13(21)10-15(18)17-14(16(19)20)9-12-6-4-3-5-7-12/h3-7,11,13-14,21H,8-10H2,1-2H3,(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046264 ((RSS) 2-(2-Benzyl-3-mercapto-5-methyl-hexanoylamin...) Show SMILES CC(C)CC(S)[C@H](Cc1ccccc1)C(=O)N[C@@H](C)C(O)=O Show InChI InChI=1S/C17H25NO3S/c1-11(2)9-15(22)14(10-13-7-5-4-6-8-13)16(19)18-12(3)17(20)21/h4-8,11-12,14-15,22H,9-10H2,1-3H3,(H,18,19)(H,20,21)/t12-,14-,15?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002019 (2-tert-Butylsulfanyl-1-mercaptomethyl-ethyl-ammoni...) Show SMILES CC(C)(C)SCC([NH3+])CS Show InChI InChI=1S/C7H17NS2/c1-7(2,3)10-5-6(8)4-9/h6,9H,4-5,8H2,1-3H3/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50038615 (2-(2-Benzyl-3-mercapto-5-phenyl-pentanoylamino)-pr...) Show SMILES CC(NC(=O)C(Cc1ccccc1)C(S)CCc1ccccc1)C(O)=O Show InChI InChI=1S/C21H25NO3S/c1-15(21(24)25)22-20(23)18(14-17-10-6-3-7-11-17)19(26)13-12-16-8-4-2-5-9-16/h2-11,15,18-19,26H,12-14H2,1H3,(H,22,23)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002037 (2-(4-Hydroxy-phenyl)-1-mercaptomethyl-ethyl-ammoni...) Show SMILES [NH3+]C(CS)Cc1ccc(O)cc1 Show InChI InChI=1S/C9H13NOS/c10-8(6-12)5-7-1-3-9(11)4-2-7/h1-4,8,11-12H,5-6,10H2/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrate				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002030 (2-Cyclohexyl-1-mercaptomethyl-ethyl-ammonium) Show SMILES [NH3+]C(CS)CC1CCCCC1 Show InChI InChI=1S/C9H19NS/c10-9(7-11)6-8-4-2-1-3-5-8/h8-9,11H,1-7,10H2/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrate				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046258 (3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...) Show SMILES CC(C)CC(S)CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C25H32N2O5S/c1-16(2)12-20(33)15-23(29)26-21(13-17-6-4-3-5-7-17)24(30)27-22(25(31)32)14-18-8-10-19(28)11-9-18/h3-11,16,20-22,28,33H,12-15H2,1-2H3,(H,26,29)(H,27,30)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50002038 (2-(2-Mercapto-3-phenyl-propionylamino)-4-methyl-pe...) Show SMILES CC(C)C[C@@H](NC(=O)C(S)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C15H21NO3S/c1-10(2)8-12(15(18)19)16-14(17)13(20)9-11-6-4-3-5-7-11/h3-7,10,12-13,20H,8-9H2,1-2H3,(H,16,17)(H,18,19)/t12-,13?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory potency against neutral endopeptidase				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046260 ((2-Benzyl-3-mercapto-butyrylamino)-acetic acid | C...) Show SMILES CC(S)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H17NO3S/c1-9(18)11(13(17)14-8-12(15)16)7-10-5-3-2-4-6-10/h2-6,9,11,18H,7-8H2,1H3,(H,14,17)(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046257 (2-[2-(2-Benzyl-3-mercapto-butyrylamino)-hexanoylam...) Show SMILES CCCCC(NC(=O)C(Cc1ccccc1)C(C)S)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C26H34N2O5S/c1-3-4-10-22(27-24(30)21(17(2)34)15-18-8-6-5-7-9-18)25(31)28-23(26(32)33)16-19-11-13-20(29)14-12-19/h5-9,11-14,17,21-23,29,34H,3-4,10,15-16H2,1-2H3,(H,27,30)(H,28,31)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046262 (3-(4-Hydroxy-phenyl)-2-(2-isopropyl-3-mercapto-5-p...) Show SMILES CC(C)C(C(S)CCc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C23H29NO4S/c1-15(2)21(20(29)13-10-16-6-4-3-5-7-16)22(26)24-19(23(27)28)14-17-8-11-18(25)12-9-17/h3-9,11-12,15,19-21,25,29H,10,13-14H2,1-2H3,(H,24,26)(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002028 (1-Benzyloxymethyl-2-mercapto-ethyl-ammonium) Show SMILES [NH3+]C(CS)COCc1ccccc1 Show InChI InChI=1S/C10H15NOS/c11-10(8-13)7-12-6-9-4-2-1-3-5-9/h1-5,10,13H,6-8,11H2/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002020 (2-Benzylsulfanyl-1-mercaptomethyl-ethyl-ammonium) Show SMILES [NH3+]C(CS)CSCc1ccccc1 Show InChI InChI=1S/C10H15NS2/c11-10(6-12)8-13-7-9-4-2-1-3-5-9/h1-5,10,12H,6-8,11H2/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002017 (1-Mercaptomethyl-2-naphthalen-2-yl-ethyl-ammonium) Show SMILES [NH3+]C(CS)Cc1ccc2ccccc2c1 Show InChI InChI=1S/C13H15NS/c14-13(9-15)8-10-5-6-11-3-1-2-4-12(11)7-10/h1-7,13,15H,8-9,14H2/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidney				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM21641 (2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...) Show SMILES OC(=O)CNC(=O)C(CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Angiotensin I converting enzyme activity using 50 microM N-Cbz-Phe-His-Leu as substrate				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046265 (2-(2-Benzyl-3-mercapto-5-phenyl-pentanoylamino)-3-...) Show SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)C(S)CCc1ccccc1 Show InChI InChI=1S/C27H29NO4S/c29-22-14-11-21(12-15-22)18-24(27(31)32)28-26(30)23(17-20-9-5-2-6-10-20)25(33)16-13-19-7-3-1-4-8-19/h1-12,14-15,23-25,29,33H,13,16-18H2,(H,28,30)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50006115 ((R)-RETRO-THIORPHAN | (RETRO)N-(1-Mercaptomethyl-2...) Show SMILES OC(=O)CC(=O)N[C@@H](CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(7-12(15)16)13-10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,14)(H,15,16)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase				J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50046266 (2-[2-(2-Benzyl-3-mercapto-butyrylamino)-3-methyl-p...) Show SMILES CCC(C)C(NC(=O)C(Cc1ccccc1)C(C)S)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C26H34N2O5S/c1-4-16(2)23(28-24(30)21(17(3)34)14-18-8-6-5-7-9-18)25(31)27-22(26(32)33)15-19-10-12-20(29)13-11-19/h5-13,16-17,21-23,29,34H,4,14-15H2,1-3H3,(H,27,31)(H,28,30)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Angiotensin I converting enzyme activity using 50 microM N-Cbz-Phe-His-Leu as substrate				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046259 (2-[2-(2-Benzyl-3-mercapto-butyrylamino)-3-methyl-b...) Show SMILES CC(C)C(NC(=O)C(Cc1ccccc1)C(C)S)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C25H32N2O5S/c1-15(2)22(27-23(29)20(16(3)33)13-17-7-5-4-6-8-17)24(30)26-21(25(31)32)14-18-9-11-19(28)12-10-18/h4-12,15-16,20-22,28,33H,13-14H2,1-3H3,(H,26,30)(H,27,29)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50046266 (2-[2-(2-Benzyl-3-mercapto-butyrylamino)-3-methyl-p...) Show SMILES CCC(C)C(NC(=O)C(Cc1ccccc1)C(C)S)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C26H34N2O5S/c1-4-16(2)23(28-24(30)21(17(3)34)14-18-8-6-5-7-9-18)25(31)27-22(26(32)33)15-19-10-12-20(29)13-11-19/h5-13,16-17,21-23,29,34H,4,14-15H2,1-3H3,(H,27,31)(H,28,30)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Mus musculus)	BDBM50452141 (CHEMBL2372595) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NCC(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c1-9(14(20)21)16-13(19)11(15-8-12(17)18)7-10-5-3-2-4-6-10/h2-6,9,11,15H,7-8H2,1H3,(H,16,19)(H,17,18)(H,20,21)/t9-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description 50% Inhibitory potency against enkephalinase from mouse striatum.				J Med Chem 26: 60-5 (1983) BindingDB Entry DOI: 10.7270/Q2Q81DP6
					More data for this Ligand-Target Pair
Neprilysin (Mus musculus)	BDBM50027522 (2-(2-Carboxy-3-phenyl-propionylamino)-4-methyl-pen...) Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)C([O-])=O)C([O-])=O Show InChI InChI=1S/C16H21NO5/c1-10(2)8-13(16(21)22)17-14(18)12(15(19)20)9-11-6-4-3-5-7-11/h3-7,10,12-13H,8-9H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description 50% Inhibitory potency against enkephalinase from mouse striatum.				J Med Chem 26: 60-5 (1983) BindingDB Entry DOI: 10.7270/Q2Q81DP6
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50046256 (2-(2-Benzyl-3-mercapto-5-methyl-hexanoylamino)-3-(...) Show SMILES CC(C)CC(S)C(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C23H29NO4S/c1-15(2)12-21(29)19(13-16-6-4-3-5-7-16)22(26)24-20(23(27)28)14-17-8-10-18(25)11-9-17/h3-11,15,19-21,25,29H,12-14H2,1-2H3,(H,24,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated by inhibiting 50% of Angiotensin I Converting Enzyme activity using 50 microM N-Cbz-Phe-His-Leu as substrate				J Med Chem 36: 87-94 (1993) BindingDB Entry DOI: 10.7270/Q26972NK
					More data for this Ligand-Target Pair
Neprilysin (Mus musculus)	BDBM50027514 (2-(2-Carboxymethyl-3-phenyl-propionylamino)-4-meth...) Show SMILES CC(C)CC(NC(=O)C(CC([O-])=O)Cc1ccccc1)C([O-])=O Show InChI InChI=1S/C17H23NO5/c1-11(2)8-14(17(22)23)18-16(21)13(10-15(19)20)9-12-6-4-3-5-7-12/h3-7,11,13-14H,8-10H2,1-2H3,(H,18,21)(H,19,20)(H,22,23)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description 50% Inhibitory potency against enkephalinase from mouse striatum.				J Med Chem 26: 60-5 (1983) BindingDB Entry DOI: 10.7270/Q2Q81DP6
					More data for this Ligand-Target Pair
Neprilysin (Mus musculus)	BDBM50139892 ((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propio...) Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C12H16N2O3/c1-8(12(16)17)14-11(15)10(13)7-9-5-3-2-4-6-9/h2-6,8,10H,7,13H2,1H3,(H,14,15)(H,16,17)/t8-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description 50% Inhibitory potency against enkephalinase from mouse striatum.				J Med Chem 26: 60-5 (1983) BindingDB Entry DOI: 10.7270/Q2Q81DP6
					More data for this Ligand-Target Pair

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