Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294221 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of rabbit beta-glo... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294221 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of rabbit beta-glo... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294220 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of rabbit beta-glo... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110843 (CHEMBL3604542) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294223 (2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-{[({[(pho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110843 (CHEMBL3604542) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294223 (2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-{[({[(pho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294221 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110892 (CHEMBL3604537) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294221 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110895 (CHEMBL3604540) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110892 (CHEMBL3604537) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110844 (CHEMBL3604543) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294223 (2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-{[({[(pho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110844 (CHEMBL3604543) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294223 (2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-{[({[(pho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110895 (CHEMBL3604540) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294221 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50316302 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 2.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110894 (CHEMBL3604539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110896 (CHEMBL3604541) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365099 (CHEMBL1951197) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110893 (CHEMBL3604538) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110894 (CHEMBL3604539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110891 (CHEMBL3604536) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365100 (CHEMBL1951195) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365099 (CHEMBL1951197) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g... | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110896 (CHEMBL3604541) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365101 (CHEMBL1951193) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g... | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294221 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365101 (CHEMBL1951193) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110891 (CHEMBL3604536) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294222 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxido-9H-puri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of rabbit beta-glo... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110893 (CHEMBL3604538) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294222 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxido-9H-puri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365103 (CHEMBL1951189) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50316302 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 5.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365102 (CHEMBL1951191) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g... | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294222 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxido-9H-puri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294220 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c... | Bioorg Med Chem Lett 19: 1921-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.053 BindingDB Entry DOI: 10.7270/Q2NP24FN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294220 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110845 (CHEMBL3351000) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365102 (CHEMBL1951191) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365100 (CHEMBL1951195) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g... | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365103 (CHEMBL1951189) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g... | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50294220 (2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g... | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110845 (CHEMBL3351000) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) Article DOI: 10.1016/j.bmc.2015.07.052 BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair |