Found 349 hits with Last Name = 'luker' and Initial = 'tj' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604064
(US11660293, Example 171 | US11660293, Example 173)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;7.71,-2.82,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | 0.437 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM603987
(US11660293, Example 61)Show SMILES Cc1nc(C(=O)N2C3CC(C3)CC2CNc2nc3ccc(F)cc3s2)c(s1)-c1ccccc1 |(-8.47,-.61,;-6.93,-.61,;-5.9,.53,;-4.49,-.1,;-3.16,.67,;-1.82,-.1,;-3.16,2.21,;-4.49,2.98,;-4.49,4.52,;-3.16,5.29,;-3.16,3.75,;-1.82,4.52,;-1.82,2.98,;-.49,2.21,;.85,2.98,;2.18,2.21,;2.34,.68,;3.85,.36,;4.62,-.97,;6.16,-.97,;6.93,.36,;8.47,.36,;6.16,1.7,;4.62,1.7,;3.59,2.84,;-4.65,-1.63,;-6.16,-1.95,;-3.56,-2.72,;-3.96,-4.2,;-2.87,-5.29,;-1.38,-4.89,;-.98,-3.41,;-2.07,-2.32,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 0.759 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604048
(US11660293, Example 152 | US11660293, Example 154)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(-.48,4.78,;-1.81,4.01,;-3.14,4.78,;-4.48,4.01,;-4.48,2.47,;-3.14,3.24,;-3.14,1.7,;-1.81,2.47,;-.48,1.7,;.86,2.47,;2.19,1.7,;2.35,.16,;3.86,-.16,;4.63,-1.49,;6.17,-1.49,;6.94,-.16,;8.48,-.16,;6.17,1.18,;4.63,1.18,;3.6,2.32,;-3.14,.16,;-1.81,-.61,;-4.48,-.61,;-5.81,.16,;-7.14,-.61,;-8.48,.16,;-7.14,-2.15,;-5.81,-2.92,;-4.48,-2.15,;-3.14,-2.92,;-2.98,-4.46,;-1.48,-4.78,;-.71,-3.44,;-1.74,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 0.871 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604115
(US11660293, Example 234 | US11660293, Example 236)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2cccnc2s1)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.02 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604067
(US11660293, Example 175 | US11660293, Example 177)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1cc(ccc1-n1nccn1)C#N |r,wU:1.0,(.96,4.78,;-.37,4.01,;-1.71,4.78,;-3.04,4.01,;-3.04,2.47,;-1.71,3.24,;-1.71,1.7,;-.37,2.47,;.96,1.7,;2.29,2.47,;3.63,1.7,;5.03,2.32,;6.07,1.18,;7.61,1.18,;8.38,-.16,;7.61,-1.49,;8.38,-2.82,;6.07,-1.49,;5.3,-.16,;3.79,.16,;-1.71,.16,;-.37,-.61,;-3.04,-.61,;-4.37,.16,;-5.71,-.61,;-5.71,-2.15,;-4.37,-2.92,;-3.04,-2.15,;-1.71,-2.92,;-1.55,-4.46,;-.04,-4.78,;.73,-3.44,;-.3,-2.3,;-7.04,.16,;-8.38,.93,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604057
(US11660293, Example 162 | US11660293, Example 164)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1nc(C)sc1-c1ncccn1 |r,wU:1.0,(.26,5.29,;-1.08,4.52,;-2.41,5.29,;-3.75,4.52,;-3.75,2.98,;-2.41,3.75,;-2.41,2.21,;-1.08,2.98,;.26,2.21,;1.59,2.98,;2.92,2.21,;4.33,2.84,;5.36,1.7,;6.9,1.7,;7.67,.36,;6.9,-.97,;7.67,-2.31,;5.36,-.97,;4.59,.36,;3.08,.68,;-2.41,.67,;-1.08,-.1,;-3.75,-.1,;-5.15,.53,;-6.18,-.61,;-7.67,-.22,;-5.41,-1.95,;-3.91,-1.63,;-2.82,-2.72,;-3.22,-4.2,;-2.13,-5.29,;-.64,-4.89,;-.24,-3.41,;-1.33,-2.32,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604092
(US11660293, Example 210 | US11660293, Example 211)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1ccc(cn1)C(F)(F)F)C(=O)c1nn(C)cc1-c1ccccc1 |r,wU:1.0,(-.01,5.26,;-1.34,4.49,;-2.68,5.26,;-4.01,4.49,;-4.01,2.95,;-2.68,3.72,;-2.68,2.18,;-1.34,2.95,;-.01,2.18,;1.32,2.95,;2.66,2.18,;2.66,.64,;3.99,-.13,;5.32,.64,;5.32,2.18,;3.99,2.95,;6.66,-.13,;7.99,.64,;6.66,-1.67,;7.99,-.9,;-2.68,.64,;-1.34,-.13,;-4.01,-.13,;-5.26,.78,;-6.5,-.13,;-7.99,.27,;-6.03,-1.59,;-4.49,-1.59,;-3.4,-2.68,;-1.91,-2.28,;-.82,-3.37,;-1.22,-4.86,;-2.71,-5.26,;-3.8,-4.17,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604064
(US11660293, Example 171 | US11660293, Example 173)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;7.71,-2.82,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM603991
(US11660293, Example 89)Show SMILES C[C@H]1C2CC(C2)N([C@H]1COc1cc2ccccc2cn1)C(=O)c1nc(C)sc1-c1ccccc1 |r,wD:7.9,1.0,(-.04,5.29,;-1.37,4.52,;-2.71,5.29,;-4.04,4.52,;-4.04,2.98,;-2.71,3.75,;-2.71,2.21,;-1.37,2.98,;-.04,2.21,;1.3,2.98,;2.63,2.21,;3.96,2.98,;5.3,2.21,;6.63,2.98,;7.96,2.21,;7.96,.67,;6.63,-.1,;5.3,.67,;3.96,-.1,;2.63,.67,;-2.71,.67,;-1.37,-.1,;-4.04,-.1,;-5.45,.53,;-6.48,-.61,;-7.96,-.22,;-5.71,-1.95,;-4.2,-1.63,;-3.11,-2.72,;-1.62,-2.32,;-.53,-3.41,;-.93,-4.89,;-2.42,-5.29,;-3.51,-4.2,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604062
(US11660293, Example 168 | US11660293, Example 170)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1cc(F)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;7.71,-2.82,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604057
(US11660293, Example 162 | US11660293, Example 164)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1nc(C)sc1-c1ncccn1 |r,wU:1.0,(.26,5.29,;-1.08,4.52,;-2.41,5.29,;-3.75,4.52,;-3.75,2.98,;-2.41,3.75,;-2.41,2.21,;-1.08,2.98,;.26,2.21,;1.59,2.98,;2.92,2.21,;4.33,2.84,;5.36,1.7,;6.9,1.7,;7.67,.36,;6.9,-.97,;7.67,-2.31,;5.36,-.97,;4.59,.36,;3.08,.68,;-2.41,.67,;-1.08,-.1,;-3.75,-.1,;-5.15,.53,;-6.18,-.61,;-7.67,-.22,;-5.41,-1.95,;-3.91,-1.63,;-2.82,-2.72,;-3.22,-4.2,;-2.13,-5.29,;-.64,-4.89,;-.24,-3.41,;-1.33,-2.32,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604066
(US11660293, Example 174)Show SMILES CCOc1ccc(C)nc1C(=O)N1C2CC(C2)[C@@H](C)C1CNc1nc2ccc(F)cc2s1 |r,wU:17.19,(-1.04,-5,;-2.37,-4.23,;-2.37,-2.69,;-3.71,-1.93,;-5.04,-2.69,;-6.37,-1.93,;-6.37,-.38,;-7.71,.38,;-5.04,.38,;-3.71,-.38,;-2.37,.38,;-1.04,-.38,;-2.37,1.93,;-3.71,2.69,;-3.71,4.23,;-2.37,5,;-2.37,3.47,;-1.04,4.23,;.29,5,;-1.04,2.69,;.29,1.93,;1.63,2.69,;2.96,1.93,;4.37,2.55,;5.4,1.41,;6.94,1.41,;7.71,.07,;6.94,-1.26,;7.71,-2.59,;5.4,-1.26,;4.63,.07,;3.12,.39,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604069
(US11660293, Example 178 | US11660293, Example 180)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccccc2s1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604132
(US11660293, Example 254 | US11660293, Example 256)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc(cn1)C(F)(F)F)C(=O)c1cc(C)ccc1-n1nccn1 |r,wU:1.0,(-.1,4.78,;-1.44,4.01,;-2.77,4.78,;-4.1,4.01,;-4.1,2.47,;-2.77,3.24,;-2.77,1.7,;-1.44,2.47,;-.1,1.7,;1.23,2.47,;2.56,1.7,;2.56,.16,;3.9,-.61,;5.28,.13,;5.23,1.7,;3.9,2.47,;6.61,-.64,;7.95,-1.41,;5.84,-1.98,;7.38,.69,;-2.77,.16,;-1.44,-.61,;-4.1,-.61,;-5.44,.16,;-6.77,-.61,;-8.11,.16,;-6.77,-2.15,;-5.44,-2.92,;-4.1,-2.15,;-2.77,-2.92,;-2.61,-4.46,;-1.1,-4.78,;-.33,-3.44,;-1.36,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604090
(US11660293, Example 207 | US11660293, Example 209)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc2cc(F)ccc2n1)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(-.67,4.78,;-2,4.01,;-3.33,4.78,;-4.67,4.01,;-4.67,2.47,;-3.33,3.24,;-3.33,1.7,;-2,2.47,;-.67,1.7,;.67,2.47,;2,1.7,;2,.16,;3.33,-.61,;4.67,.16,;6,-.61,;7.34,.16,;8.67,-.61,;7.34,1.7,;6,2.47,;4.67,1.7,;3.33,2.47,;-3.33,.16,;-2,-.61,;-4.67,-.61,;-6,.16,;-7.34,-.61,;-8.67,.16,;-7.34,-2.15,;-6,-2.92,;-4.67,-2.15,;-3.33,-2.92,;-3.17,-4.46,;-1.67,-4.78,;-.9,-3.44,;-1.93,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM603993
(US11660293, Example 93)Show SMILES C[C@@H]1C2CC(C2)N([C@H]1COc1ccc(F)cc1)C(=O)c1nc(C)ccc1-c1ncccn1 |r,wU:1.0,wD:7.9,(.67,5,;-.67,4.23,;-2,5,;-3.33,4.23,;-3.33,2.69,;-2,3.47,;-2,1.93,;-.67,2.69,;.67,1.93,;2,2.69,;3.33,1.93,;4.67,2.69,;6,1.93,;6,.39,;7.34,-.38,;4.67,-.38,;3.33,.38,;-2,.38,;-.67,-.38,;-3.33,-.38,;-4.67,.38,;-6,-.38,;-7.34,.38,;-6,-1.93,;-4.67,-2.69,;-3.33,-1.93,;-2,-2.69,;-.67,-1.92,;.67,-2.69,;.67,-4.23,;-.67,-5,;-2,-4.23,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604098
(US11660293, Example 218 | US11660293, Example 219)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2o1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;7.71,-2.82,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 1.95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604092
(US11660293, Example 210 | US11660293, Example 211)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1ccc(cn1)C(F)(F)F)C(=O)c1nn(C)cc1-c1ccccc1 |r,wU:1.0,(-.01,5.26,;-1.34,4.49,;-2.68,5.26,;-4.01,4.49,;-4.01,2.95,;-2.68,3.72,;-2.68,2.18,;-1.34,2.95,;-.01,2.18,;1.32,2.95,;2.66,2.18,;2.66,.64,;3.99,-.13,;5.32,.64,;5.32,2.18,;3.99,2.95,;6.66,-.13,;7.99,.64,;6.66,-1.67,;7.99,-.9,;-2.68,.64,;-1.34,-.13,;-4.01,-.13,;-5.26,.78,;-6.5,-.13,;-7.99,.27,;-6.03,-1.59,;-4.49,-1.59,;-3.4,-2.68,;-1.91,-2.28,;-.82,-3.37,;-1.22,-4.86,;-2.71,-5.26,;-3.8,-4.17,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 2.04 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604048
(US11660293, Example 152 | US11660293, Example 154)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(-.48,4.78,;-1.81,4.01,;-3.14,4.78,;-4.48,4.01,;-4.48,2.47,;-3.14,3.24,;-3.14,1.7,;-1.81,2.47,;-.48,1.7,;.86,2.47,;2.19,1.7,;2.35,.16,;3.86,-.16,;4.63,-1.49,;6.17,-1.49,;6.94,-.16,;8.48,-.16,;6.17,1.18,;4.63,1.18,;3.6,2.32,;-3.14,.16,;-1.81,-.61,;-4.48,-.61,;-5.81,.16,;-7.14,-.61,;-8.48,.16,;-7.14,-2.15,;-5.81,-2.92,;-4.48,-2.15,;-3.14,-2.92,;-2.98,-4.46,;-1.48,-4.78,;-.71,-3.44,;-1.74,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 2.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604053
(US11660293, Example 158 | US11660293, Example 159 ...)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc2ccccc2n1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(,4.78,;-1.33,4.01,;-2.67,4.78,;-4,4.01,;-4,2.47,;-2.67,3.24,;-2.67,1.7,;-1.33,2.47,;,1.7,;1.33,2.47,;2.67,1.7,;2.67,.16,;4,-.61,;5.33,.16,;6.67,-.61,;8,.16,;8,1.7,;6.67,2.47,;5.33,1.7,;4,2.47,;-2.67,.16,;-1.33,-.61,;-4,-.61,;-5.33,.16,;-6.67,-.61,;-8,.16,;-6.67,-2.15,;-5.33,-2.92,;-4,-2.15,;-2.67,-2.92,;-2.51,-4.46,;-1,-4.78,;-.23,-3.44,;-1.26,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 2.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604087
(US11660293, Example 203 | US11660293, Example 205)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc(cn1)C(F)(F)F)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(,4.78,;-1.33,4.01,;-2.67,4.78,;-4,4.01,;-4,2.47,;-2.67,3.24,;-2.67,1.7,;-1.33,2.47,;,1.7,;1.33,2.47,;2.67,1.7,;2.67,.16,;4,-.61,;5.33,.16,;5.33,1.7,;4,2.47,;6.67,-.61,;8,.16,;6.67,-2.15,;8,-1.38,;-2.67,.16,;-1.33,-.61,;-4,-.61,;-5.33,.16,;-6.67,-.61,;-8,.16,;-6.67,-2.15,;-5.33,-2.92,;-4,-2.15,;-2.67,-2.92,;-2.51,-4.46,;-1,-4.78,;-.23,-3.44,;-1.26,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 2.57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604069
(US11660293, Example 178 | US11660293, Example 180)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccccc2s1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.02 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604075
(US11660293, Example 187 | US11660293, Example 189)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc2ccccc2n1)C(=O)c1cc(F)ccc1-n1nccn1 |r,wU:1.0,(.67,4.78,;-.67,4.01,;-2,4.78,;-3.33,4.01,;-3.33,2.47,;-2,3.24,;-2,1.7,;-.67,2.47,;.67,1.7,;2,2.47,;3.33,1.7,;4.67,2.47,;6,1.7,;6,.16,;7.34,-.61,;7.34,-2.15,;6,-2.92,;4.67,-2.15,;4.67,-.61,;3.33,.16,;-2,.16,;-.67,-.61,;-3.33,-.61,;-4.67,.16,;-6,-.61,;-7.34,.16,;-6,-2.15,;-4.67,-2.92,;-3.33,-2.15,;-2,-2.92,;-1.84,-4.46,;-.33,-4.78,;.44,-3.44,;-.59,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604011
(US11660293, Example 113 | US11660293, Example 115)Show SMILES C[C@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1nc(C)sc1-c1ncccn1 |r,wD:1.0,TLB:0:1:3:5,THB:17:6:3:5,(.63,5.29,;-.7,4.52,;-2.04,5.29,;-3.37,4.52,;-3.37,2.98,;-2.04,3.75,;-2.04,2.21,;-.7,2.98,;.63,2.21,;1.96,2.98,;3.3,2.21,;4.63,2.98,;5.96,2.21,;5.96,.67,;7.3,-.1,;4.63,-.1,;3.3,.67,;-2.04,.67,;-.7,-.1,;-3.37,-.1,;-4.78,.53,;-5.81,-.61,;-7.3,-.22,;-5.04,-1.95,;-3.53,-1.63,;-2.44,-2.72,;-.96,-2.32,;.13,-3.41,;-.27,-4.89,;-1.75,-5.29,;-2.84,-4.2,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604005
(US11660293, Example 106 | US11660293, Example 108)Show SMILES C[C@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1nc(C)ccc1-c1nccs1 |r,wD:1.0,(.67,4.78,;-.67,4.01,;-2,4.78,;-3.33,4.01,;-3.33,2.47,;-2,3.24,;-2,1.7,;-.67,2.47,;.67,1.7,;2,2.47,;3.33,1.7,;4.67,2.47,;6,1.7,;6,.16,;7.34,-.61,;4.67,-.61,;3.33,.16,;-2,.16,;-.67,-.61,;-3.33,-.61,;-4.67,.16,;-6,-.61,;-7.34,.16,;-6,-2.15,;-4.67,-2.92,;-3.33,-2.15,;-2,-2.92,;-.59,-2.3,;.44,-3.44,;-.33,-4.78,;-1.84,-4.46,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604062
(US11660293, Example 168 | US11660293, Example 170)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1cc(F)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;7.71,-2.82,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604111
(US11660293, Example 228 | US11660293, Example 230)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2cccnc2s1)C(=O)c1cc(F)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM603992
(US11660293, Example 91)Show SMILES C[C@H]1C2CC(C2)N([C@H]1COc1ccc(F)cc1)C(=O)c1nc(C)ccc1-c1ncccn1 |r,wD:7.9,1.0,(.67,5,;-.67,4.23,;-2,5,;-3.33,4.23,;-3.33,2.69,;-2,3.47,;-2,1.93,;-.67,2.69,;.67,1.93,;2,2.69,;3.33,1.93,;4.67,2.69,;6,1.93,;6,.39,;7.34,-.38,;4.67,-.38,;3.33,.38,;-2,.38,;-.67,-.38,;-3.33,-.38,;-4.67,.38,;-6,-.38,;-7.34,.38,;-6,-1.93,;-4.67,-2.69,;-3.33,-1.93,;-2,-2.69,;-.67,-1.92,;.67,-2.69,;.67,-4.23,;-.67,-5,;-2,-4.23,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604103
(US11660293, Example 225 | US11660293, Example 226 ...)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccccc2o1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604090
(US11660293, Example 207 | US11660293, Example 209)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc2cc(F)ccc2n1)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(-.67,4.78,;-2,4.01,;-3.33,4.78,;-4.67,4.01,;-4.67,2.47,;-3.33,3.24,;-3.33,1.7,;-2,2.47,;-.67,1.7,;.67,2.47,;2,1.7,;2,.16,;3.33,-.61,;4.67,.16,;6,-.61,;7.34,.16,;8.67,-.61,;7.34,1.7,;6,2.47,;4.67,1.7,;3.33,2.47,;-3.33,.16,;-2,-.61,;-4.67,-.61,;-6,.16,;-7.34,-.61,;-8.67,.16,;-7.34,-2.15,;-6,-2.92,;-4.67,-2.15,;-3.33,-2.92,;-3.17,-4.46,;-1.67,-4.78,;-.9,-3.44,;-1.93,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604115
(US11660293, Example 234 | US11660293, Example 236)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2cccnc2s1)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604020
(US11660293, Example 123 | US11660293, Example 124)Show SMILES C[C@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1nc(C)sc1-c1ccccn1 |r,wD:1.0,TLB:0:1:3:5,THB:17:6:3:5,(.63,5.29,;-.7,4.52,;-2.04,5.29,;-3.37,4.52,;-3.37,2.98,;-2.04,3.75,;-2.04,2.21,;-.7,2.98,;.63,2.21,;1.96,2.98,;3.3,2.21,;3.3,.67,;4.63,-.1,;5.96,.67,;7.3,-.1,;5.96,2.21,;4.63,2.98,;-2.04,.67,;-.7,-.1,;-3.37,-.1,;-4.78,.53,;-5.81,-.61,;-7.3,-.22,;-5.04,-1.95,;-3.53,-1.63,;-2.44,-2.72,;-2.84,-4.2,;-1.75,-5.29,;-.27,-4.89,;.13,-3.41,;-.96,-2.32,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604073
(US11660293, Example 184 | US11660293, Example 186)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2cccnc2s1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604067
(US11660293, Example 175 | US11660293, Example 177)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1cc(ccc1-n1nccn1)C#N |r,wU:1.0,(.96,4.78,;-.37,4.01,;-1.71,4.78,;-3.04,4.01,;-3.04,2.47,;-1.71,3.24,;-1.71,1.7,;-.37,2.47,;.96,1.7,;2.29,2.47,;3.63,1.7,;5.03,2.32,;6.07,1.18,;7.61,1.18,;8.38,-.16,;7.61,-1.49,;8.38,-2.82,;6.07,-1.49,;5.3,-.16,;3.79,.16,;-1.71,.16,;-.37,-.61,;-3.04,-.61,;-4.37,.16,;-5.71,-.61,;-5.71,-2.15,;-4.37,-2.92,;-3.04,-2.15,;-1.71,-2.92,;-1.55,-4.46,;-.04,-4.78,;.73,-3.44,;-.3,-2.3,;-7.04,.16,;-8.38,.93,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604113
(US11660293, Example 231 | US11660293, Example 233)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2cccnc2s1)C(=O)c1cc(ccc1-n1nccn1)C#N |r,wU:1.0,(.96,4.78,;-.37,4.01,;-1.71,4.78,;-3.04,4.01,;-3.04,2.47,;-1.71,3.24,;-1.71,1.7,;-.37,2.47,;.96,1.7,;2.29,2.47,;3.63,1.7,;5.03,2.32,;6.07,1.18,;7.61,1.18,;8.38,-.16,;7.61,-1.49,;6.07,-1.49,;5.3,-.16,;3.79,.16,;-1.71,.16,;-.37,-.61,;-3.04,-.61,;-4.37,.16,;-5.71,-.61,;-5.71,-2.15,;-4.37,-2.92,;-3.04,-2.15,;-1.71,-2.92,;-1.55,-4.46,;-.04,-4.78,;.73,-3.44,;-.3,-2.3,;-7.04,.16,;-8.38,.93,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604053
(US11660293, Example 158 | US11660293, Example 159 ...)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc2ccccc2n1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(,4.78,;-1.33,4.01,;-2.67,4.78,;-4,4.01,;-4,2.47,;-2.67,3.24,;-2.67,1.7,;-1.33,2.47,;,1.7,;1.33,2.47,;2.67,1.7,;2.67,.16,;4,-.61,;5.33,.16,;6.67,-.61,;8,.16,;8,1.7,;6.67,2.47,;5.33,1.7,;4,2.47,;-2.67,.16,;-1.33,-.61,;-4,-.61,;-5.33,.16,;-6.67,-.61,;-8,.16,;-6.67,-2.15,;-5.33,-2.92,;-4,-2.15,;-2.67,-2.92,;-2.51,-4.46,;-1,-4.78,;-.23,-3.44,;-1.26,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604132
(US11660293, Example 254 | US11660293, Example 256)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc(cn1)C(F)(F)F)C(=O)c1cc(C)ccc1-n1nccn1 |r,wU:1.0,(-.1,4.78,;-1.44,4.01,;-2.77,4.78,;-4.1,4.01,;-4.1,2.47,;-2.77,3.24,;-2.77,1.7,;-1.44,2.47,;-.1,1.7,;1.23,2.47,;2.56,1.7,;2.56,.16,;3.9,-.61,;5.28,.13,;5.23,1.7,;3.9,2.47,;6.61,-.64,;7.95,-1.41,;5.84,-1.98,;7.38,.69,;-2.77,.16,;-1.44,-.61,;-4.1,-.61,;-5.44,.16,;-6.77,-.61,;-8.11,.16,;-6.77,-2.15,;-5.44,-2.92,;-4.1,-2.15,;-2.77,-2.92,;-2.61,-4.46,;-1.1,-4.78,;-.33,-3.44,;-1.36,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 4.27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604098
(US11660293, Example 218 | US11660293, Example 219)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2o1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;7.71,-2.82,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 4.68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604103
(US11660293, Example 225 | US11660293, Example 226 ...)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccccc2o1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 4.79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604071
(US11660293, Example 181 | US11660293, Example 183)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1ccc(cn1)C(F)(F)F)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(,4.78,;-1.33,4.01,;-2.67,4.78,;-4,4.01,;-4,2.47,;-2.67,3.24,;-2.67,1.7,;-1.33,2.47,;,1.7,;1.33,2.47,;2.67,1.7,;2.67,.16,;4,-.61,;5.38,.13,;5.33,1.7,;4,2.47,;6.72,-.64,;8.05,-1.41,;5.95,-1.98,;7.49,.69,;-2.67,.16,;-1.33,-.61,;-4,-.61,;-5.33,.16,;-6.67,-.61,;-8,.16,;-6.67,-2.15,;-5.33,-2.92,;-4,-2.15,;-2.67,-2.92,;-2.51,-4.46,;-1,-4.78,;-.23,-3.44,;-1.26,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604119
(US11660293, Example 239 | US11660293, Example 241)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1ncc(cn1)C(F)(F)F)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(,4.78,;-1.33,4.01,;-2.67,4.78,;-4,4.01,;-4,2.47,;-2.67,3.24,;-2.67,1.7,;-1.33,2.47,;,1.7,;1.33,2.47,;2.67,1.7,;4,2.47,;5.33,1.7,;5.33,.16,;4,-.61,;2.67,.16,;6.67,-.61,;8,.16,;6.67,-2.15,;8,-1.38,;-2.67,.16,;-1.33,-.61,;-4,-.61,;-5.33,.16,;-6.67,-.61,;-8,.16,;-6.67,-2.15,;-5.33,-2.92,;-4,-2.15,;-2.67,-2.92,;-2.51,-4.46,;-1,-4.78,;-.23,-3.44,;-1.26,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 5.37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM603986
(US11660293, Example 60)Show SMILES Cc1nc(C(=O)N2C3CC(C3)CC2CNc2ccc3ccccc3n2)c(s1)-c1ccccc1 |(-7.96,-.22,;-6.48,-.61,;-5.45,.53,;-4.04,-.1,;-2.71,.67,;-1.37,-.1,;-2.71,2.21,;-4.04,2.98,;-4.04,4.52,;-2.71,5.29,;-2.71,3.75,;-1.37,4.52,;-1.37,2.98,;-.04,2.21,;1.3,2.98,;2.63,2.21,;2.63,.67,;3.96,-.1,;5.3,.67,;6.63,-.1,;7.96,.67,;7.96,2.21,;6.63,2.98,;5.3,2.21,;3.96,2.98,;-4.2,-1.63,;-5.71,-1.95,;-3.11,-2.72,;-1.62,-2.32,;-.53,-3.41,;-.93,-4.89,;-2.42,-5.29,;-3.51,-4.2,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 5.37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604121
(US11660293, Example 242 | US11660293, Example 244)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2cccnc2o1)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(.29,4.78,;-1.04,4.01,;-2.37,4.78,;-3.71,4.01,;-3.71,2.47,;-2.37,3.24,;-2.37,1.7,;-1.04,2.47,;.29,1.7,;1.63,2.47,;2.96,1.7,;4.37,2.32,;5.4,1.18,;6.94,1.18,;7.71,-.16,;6.94,-1.49,;5.4,-1.49,;4.63,-.16,;3.12,.16,;-2.37,.16,;-1.04,-.61,;-3.71,-.61,;-5.04,.16,;-6.37,-.61,;-7.71,.16,;-6.37,-2.15,;-5.04,-2.92,;-3.71,-2.15,;-2.37,-2.92,;-2.21,-4.46,;-.71,-4.78,;.06,-3.44,;-.97,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 5.62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604083
(US11660293, Example 198 | US11660293, Example 200)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc2cc(F)ccc2n1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wU:1.0,(-.67,4.78,;-2,4.01,;-3.33,4.78,;-4.67,4.01,;-4.67,2.47,;-3.33,3.24,;-3.33,1.7,;-2,2.47,;-.67,1.7,;.67,2.47,;2,1.7,;2,.16,;3.33,-.61,;4.67,.16,;6,-.61,;7.34,.16,;8.67,-.61,;7.34,1.7,;6,2.47,;4.67,1.7,;3.33,2.47,;-3.33,.16,;-2,-.61,;-4.67,-.61,;-6,.16,;-7.34,-.61,;-8.67,.16,;-7.34,-2.15,;-6,-2.92,;-4.67,-2.15,;-3.33,-2.92,;-3.17,-4.46,;-1.67,-4.78,;-.9,-3.44,;-1.93,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 5.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604011
(US11660293, Example 113 | US11660293, Example 115)Show SMILES C[C@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1nc(C)sc1-c1ncccn1 |r,wD:1.0,TLB:0:1:3:5,THB:17:6:3:5,(.63,5.29,;-.7,4.52,;-2.04,5.29,;-3.37,4.52,;-3.37,2.98,;-2.04,3.75,;-2.04,2.21,;-.7,2.98,;.63,2.21,;1.96,2.98,;3.3,2.21,;4.63,2.98,;5.96,2.21,;5.96,.67,;7.3,-.1,;4.63,-.1,;3.3,.67,;-2.04,.67,;-.7,-.1,;-3.37,-.1,;-4.78,.53,;-5.81,-.61,;-7.3,-.22,;-5.04,-1.95,;-3.53,-1.63,;-2.44,-2.72,;-.96,-2.32,;.13,-3.41,;-.27,-4.89,;-1.75,-5.29,;-2.84,-4.2,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 6.17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604113
(US11660293, Example 231 | US11660293, Example 233)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2cccnc2s1)C(=O)c1cc(ccc1-n1nccn1)C#N |r,wU:1.0,(.96,4.78,;-.37,4.01,;-1.71,4.78,;-3.04,4.01,;-3.04,2.47,;-1.71,3.24,;-1.71,1.7,;-.37,2.47,;.96,1.7,;2.29,2.47,;3.63,1.7,;5.03,2.32,;6.07,1.18,;7.61,1.18,;8.38,-.16,;7.61,-1.49,;6.07,-1.49,;5.3,-.16,;3.79,.16,;-1.71,.16,;-.37,-.61,;-3.04,-.61,;-4.37,.16,;-5.71,-.61,;-5.71,-2.15,;-4.37,-2.92,;-3.04,-2.15,;-1.71,-2.92,;-1.55,-4.46,;-.04,-4.78,;.73,-3.44,;-.3,-2.3,;-7.04,.16,;-8.38,.93,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604003
(US11660293, Example 103 | US11660293, Example 105)Show SMILES C[C@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1nc(C)ccc1-n1nccn1 |r,wD:1.0,(.67,4.78,;-.67,4.01,;-2,4.78,;-3.33,4.01,;-3.33,2.47,;-2,3.24,;-2,1.7,;-.67,2.47,;.67,1.7,;2,2.47,;3.33,1.7,;4.67,2.47,;6,1.7,;6,.16,;7.34,-.61,;4.67,-.61,;3.33,.16,;-2,.16,;-.67,-.61,;-3.33,-.61,;-4.67,.16,;-6,-.61,;-7.34,.16,;-6,-2.15,;-4.67,-2.92,;-3.33,-2.15,;-2,-2.92,;-1.84,-4.46,;-.33,-4.78,;.44,-3.44,;-.59,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604075
(US11660293, Example 187 | US11660293, Example 189)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc2ccccc2n1)C(=O)c1cc(F)ccc1-n1nccn1 |r,wU:1.0,(.67,4.78,;-.67,4.01,;-2,4.78,;-3.33,4.01,;-3.33,2.47,;-2,3.24,;-2,1.7,;-.67,2.47,;.67,1.7,;2,2.47,;3.33,1.7,;4.67,2.47,;6,1.7,;6,.16,;7.34,-.61,;7.34,-2.15,;6,-2.92,;4.67,-2.15,;4.67,-.61,;3.33,.16,;-2,.16,;-.67,-.61,;-3.33,-.61,;-4.67,.16,;-6,-.61,;-7.34,.16,;-6,-2.15,;-4.67,-2.92,;-3.33,-2.15,;-2,-2.92,;-1.84,-4.46,;-.33,-4.78,;.44,-3.44,;-.59,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 6.46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM603996
(US11660293, Example 96)Show SMILES C[C@@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1nc(C)ccc1-c1nccs1 |r,wU:1.0,(.67,4.78,;-.67,4.01,;-2,4.78,;-3.33,4.01,;-3.33,2.47,;-2,3.24,;-2,1.7,;-.67,2.47,;.67,1.7,;2,2.47,;3.33,1.7,;3.33,.16,;4.67,-.61,;6,.16,;7.34,-.61,;6,1.7,;4.67,2.47,;-2,.16,;-.67,-.61,;-3.33,-.61,;-4.67,.16,;-6,-.61,;-7.34,.16,;-6,-2.15,;-4.67,-2.92,;-3.33,-2.15,;-2,-2.92,;-.59,-2.3,;.44,-3.44,;-.33,-4.78,;-1.84,-4.46,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 6.61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM604087
(US11660293, Example 203 | US11660293, Example 205)Show SMILES C[C@@H]1C2CC(C2)N(C1CNc1cnc(cn1)C(F)(F)F)C(=O)c1cc(Cl)ccc1-n1nccn1 |r,wU:1.0,(,4.78,;-1.33,4.01,;-2.67,4.78,;-4,4.01,;-4,2.47,;-2.67,3.24,;-2.67,1.7,;-1.33,2.47,;,1.7,;1.33,2.47,;2.67,1.7,;2.67,.16,;4,-.61,;5.33,.16,;5.33,1.7,;4,2.47,;6.67,-.61,;8,.16,;6.67,-2.15,;8,-1.38,;-2.67,.16,;-1.33,-.61,;-4,-.61,;-5.33,.16,;-6.67,-.61,;-8,.16,;-6.67,-2.15,;-5.33,-2.92,;-4,-2.15,;-2.67,-2.92,;-2.51,-4.46,;-1,-4.78,;-.23,-3.44,;-1.26,-2.3,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 6.76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2280CJQ |
More data for this
Ligand-Target Pair | |
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