Compile Data Set for Download or QSAR

Found 36 hits with Last Name = 'lynch' and Initial = 'ma'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) Show SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |r,c:27,t:23| Show InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316567 (1-(2-chloropyridin-4-yl)-2,2,2-trifluoro-1-(1-(4-f...) Show SMILES OC(c1ccnc(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4N3O/c21-18-10-14(7-8-26-18)19(29,20(23,24)25)13-1-6-17-12(9-13)11-27-28(17)16-4-2-15(22)3-5-16/h1-11,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316562 (2-chloro-4-(2,2,2-trifluoro-1-(1-(4-fluorophenyl)-...) Show SMILES OC(c1ccc(F)c(c1)C#N)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H12F5N3O/c23-17-3-5-18(6-4-17)30-20-8-2-16(10-14(20)12-29-30)21(31,22(25,26)27)15-1-7-19(24)13(9-15)11-28/h1-10,12,31H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316565 (1-(2-chlorophenyl)-2,2,2-trifluoro-1-(1-(4-fluorop...) Show SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C21H13ClF4N2O/c22-18-4-2-1-3-17(18)20(29,21(24,25)26)14-5-10-19-13(11-14)12-27-28(19)16-8-6-15(23)7-9-16/h1-12,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316558 (2,2,2-trifluoro-1-(1-(4-fluorophenyl)-1H-indazol-5...) Show SMILES Cc1cccc(c1)C(O)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H16F4N2O/c1-14-3-2-4-16(11-14)21(29,22(24,25)26)17-5-10-20-15(12-17)13-27-28(20)19-8-6-18(23)7-9-19/h2-13,29H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316562 (2-chloro-4-(2,2,2-trifluoro-1-(1-(4-fluorophenyl)-...) Show SMILES OC(c1ccc(F)c(c1)C#N)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H12F5N3O/c23-17-3-5-18(6-4-17)30-20-8-2-16(10-14(20)12-29-30)21(31,22(25,26)27)15-1-7-19(24)13(9-15)11-28/h1-10,12,31H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316564 (2,2,2-trifluoro-1-(2-fluorophenyl)-1-(1-(4-fluorop...) Show SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1ccccc1F)C(F)(F)F Show InChI InChI=1S/C21H13F5N2O/c22-15-6-8-16(9-7-15)28-19-10-5-14(11-13(19)12-27-28)20(29,21(24,25)26)17-3-1-2-4-18(17)23/h1-12,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316569 (2,2,2-trifluoro-1-(4-fluoro-3-methylphenyl)-1-(1-(...) Show SMILES Cc1cc(ccc1F)C(O)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H15F5N2O/c1-13-10-15(2-8-19(13)24)21(30,22(25,26)27)16-3-9-20-14(11-16)12-28-29(20)18-6-4-17(23)5-7-18/h2-12,30H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316559 (1-(3-chlorophenyl)-2,2,2-trifluoro-1-(1-(4-fluorop...) Show SMILES OC(c1cccc(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H13ClF4N2O/c22-16-3-1-2-14(11-16)20(29,21(24,25)26)15-4-9-19-13(10-15)12-27-28(19)18-7-5-17(23)6-8-18/h1-12,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316555 (2,2,2-trifluoro-1-(4-fluorophenyl)-1-(1-(4-fluorop...) Show SMILES OC(c1ccc(F)cc1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H13F5N2O/c22-16-4-1-14(2-5-16)20(29,21(24,25)26)15-3-10-19-13(11-15)12-27-28(19)18-8-6-17(23)7-9-18/h1-12,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316555 (2,2,2-trifluoro-1-(4-fluorophenyl)-1-(1-(4-fluorop...) Show SMILES OC(c1ccc(F)cc1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H13F5N2O/c22-16-4-1-14(2-5-16)20(29,21(24,25)26)15-3-10-19-13(11-15)12-27-28(19)18-8-6-17(23)7-9-18/h1-12,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316566 ((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...) Show SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1cccc(Cl)c1Cl)C(F)(F)F Show InChI InChI=1S/C21H12Cl2F4N2O/c22-17-3-1-2-16(19(17)23)20(30,21(25,26)27)13-4-9-18-12(10-13)11-28-29(18)15-7-5-14(24)6-8-15/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316566 ((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...) Show SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1cccc(Cl)c1Cl)C(F)(F)F Show InChI InChI=1S/C21H12Cl2F4N2O/c22-17-3-1-2-16(19(17)23)20(30,21(25,26)27)13-4-9-18-12(10-13)11-28-29(18)15-7-5-14(24)6-8-15/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316560 (3-(2,2,2-trifluoro-1-(1-(4-fluorophenyl)-1H-indazo...) Show SMILES OC(c1cccc(c1)C#N)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H13F4N3O/c23-18-5-7-19(8-6-18)29-20-9-4-17(11-15(20)13-28-29)21(30,22(24,25)26)16-3-1-2-14(10-16)12-27/h1-11,13,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316557 (1-(3,4-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4-flu...) Show SMILES OC(c1ccc(Cl)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12Cl2F4N2O/c22-17-7-1-14(10-18(17)23)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(24)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316563 (2,2,2-trifluoro-1-(1-(4-fluorophenyl)-1H-indazol-5...) Show SMILES Cc1ccccc1C(O)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H16F4N2O/c1-14-4-2-3-5-19(14)21(29,22(24,25)26)16-6-11-20-15(12-16)13-27-28(20)18-9-7-17(23)8-10-18/h2-13,29H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316556 (2,2,2-trifluoro-1-(1-(4-fluorophenyl)-1H-indazol-5...) Show SMILES Cc1ccc(cc1)C(O)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H16F4N2O/c1-14-2-4-16(5-3-14)21(29,22(24,25)26)17-6-11-20-15(12-17)13-27-28(20)19-9-7-18(23)8-10-19/h2-13,29H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316554 (1-(4-fluorophenyl)-1-(1-(4-fluorophenyl)-1H-indazo...) Show SMILES CC(O)(c1ccc(F)cc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H16F2N2O/c1-21(26,15-2-5-17(22)6-3-15)16-4-11-20-14(12-16)13-24-25(20)19-9-7-18(23)8-10-19/h2-13,26H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316555 (2,2,2-trifluoro-1-(4-fluorophenyl)-1-(1-(4-fluorop...) Show SMILES OC(c1ccc(F)cc1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H13F5N2O/c22-16-4-1-14(2-5-16)20(29,21(24,25)26)15-3-10-19-13(11-15)12-27-28(19)18-8-6-17(23)7-9-18/h1-12,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50316566 ((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...) Show SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1cccc(Cl)c1Cl)C(F)(F)F Show InChI InChI=1S/C21H12Cl2F4N2O/c22-17-3-1-2-16(19(17)23)20(30,21(25,26)27)13-4-9-18-12(10-13)11-28-29(18)15-7-5-14(24)6-8-15/h1-11,30H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp method				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316553 ((4-fluorophenyl)(1-(4-fluorophenyl)-1H-indazol-5-y...) Show SMILES OC(c1ccc(F)cc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H14F2N2O/c21-16-4-1-13(2-5-16)20(25)14-3-10-19-15(11-14)12-23-24(19)18-8-6-17(22)7-9-18/h1-12,20,25H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assay				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50316569 (2,2,2-trifluoro-1-(4-fluoro-3-methylphenyl)-1-(1-(...) Show SMILES Cc1cc(ccc1F)C(O)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H15F5N2O/c1-13-10-15(2-8-19(13)24)21(30,22(25,26)27)16-3-9-20-14(11-16)12-28-29(20)18-6-4-17(23)5-7-18/h2-12,30H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp method				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50316562 (2-chloro-4-(2,2,2-trifluoro-1-(1-(4-fluorophenyl)-...) Show SMILES OC(c1ccc(F)c(c1)C#N)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H12F5N3O/c23-17-3-5-18(6-4-17)30-20-8-2-16(10-14(20)12-29-30)21(31,22(25,26)27)15-1-7-19(24)13(9-15)11-28/h1-10,12,31H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp method				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp method				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50316567 (1-(2-chloropyridin-4-yl)-2,2,2-trifluoro-1-(1-(4-f...) Show SMILES OC(c1ccnc(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4N3O/c21-18-10-14(7-8-26-18)19(29,20(23,24)25)13-1-6-17-12(9-13)11-27-28(17)16-4-2-15(22)3-5-16/h1-11,29H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp method				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) Show SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |r,c:27,t:23| Show InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human MDA-kb2 cells transfected with MMTV-LUC assessed as induction of MMTV-LTR/promoter linked LUC ge...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316566 ((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...) Show SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1cccc(Cl)c1Cl)C(F)(F)F Show InChI InChI=1S/C21H12Cl2F4N2O/c22-17-3-1-2-16(19(17)23)20(30,21(25,26)27)13-4-9-18-12(10-13)11-28-29(18)15-7-5-14(24)6-8-15/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human MDA-kb2 cells transfected with MMTV-LUC assessed as induction of MMTV-LTR/promoter linked LUC ge...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) Show SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |r,c:27,t:23| Show InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human MDA-kb2 cells transfected with MMTV-LUC assessed as induction of MMTV-LTR/promoter linked LUC ge...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316561 (1-(2-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(...) Show SMILES OC(c1ccc(F)c(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2O/c22-17-10-14(1-7-18(17)24)20(30,21(25,26)27)13-2-8-19-12(9-13)11-28-29(19)16-5-3-15(23)4-6-16/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316569 (2,2,2-trifluoro-1-(4-fluoro-3-methylphenyl)-1-(1-(...) Show SMILES Cc1cc(ccc1F)C(O)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H15F5N2O/c1-13-10-15(2-8-19(13)24)21(30,22(25,26)27)16-3-9-20-14(11-16)12-28-29(20)18-6-4-17(23)5-7-18/h2-12,30H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316562 (2-chloro-4-(2,2,2-trifluoro-1-(1-(4-fluorophenyl)-...) Show SMILES OC(c1ccc(F)c(c1)C#N)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C22H12F5N3O/c23-17-3-5-18(6-4-17)30-20-8-2-16(10-14(20)12-29-30)21(31,22(25,26)27)15-1-7-19(24)13(9-15)11-28/h1-10,12,31H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316567 (1-(2-chloropyridin-4-yl)-2,2,2-trifluoro-1-(1-(4-f...) Show SMILES OC(c1ccnc(Cl)c1)(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4N3O/c21-18-10-14(7-8-26-18)19(29,20(23,24)25)13-1-6-17-12(9-13)11-27-28(17)16-4-2-15(22)3-5-16/h1-11,29H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	627	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50316566 ((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...) Show SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1cccc(Cl)c1Cl)C(F)(F)F Show InChI InChI=1S/C21H12Cl2F4N2O/c22-17-3-1-2-16(19(17)23)20(30,21(25,26)27)13-4-9-18-12(10-13)11-28-29(18)15-7-5-14(24)6-8-15/h1-11,30H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...				Bioorg Med Chem Lett 20: 3017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.012 BindingDB Entry DOI: 10.7270/Q23779P9
					More data for this Ligand-Target Pair