Compile Data Set for Download or QSAR

Found 353 hits with Last Name = 'mackinnon' and Initial = 'ac'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228318 (CHEMBL279807) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H26N2O3S/c1-23-15-5-6-16-13(10-15)7-9-19-12-14-4-3-8-20(24(2,21)22)17(14)11-18(16)19/h5-6,10,14,17-18H,3-4,7-9,11-12H2,1-2H3/t14-,17-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description In vitro inhibition of rat liver dihydrofolate reductase.				J Med Chem 32: 2034-6 (1989) BindingDB Entry DOI: 10.7270/Q2WH2S78
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228318 (CHEMBL279807) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H26N2O3S/c1-23-15-5-6-16-13(10-15)7-9-19-12-14-4-3-8-20(24(2,21)22)17(14)11-18(16)19/h5-6,10,14,17-18H,3-4,7-9,11-12H2,1-2H3/t14-,17-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229080 (CHEMBL349665) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C23H28N2O3S/c1-28-19-8-10-20(11-9-19)29(26,27)25-13-4-6-18-16-24-14-12-17-5-2-3-7-21(17)23(24)15-22(18)25/h2-3,5,7-11,18,22-23H,4,6,12-16H2,1H3/t18-,22+,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.457	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229162 (CHEMBL349747) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)CCOC Show InChI InChI=1S/C20H30N2O4S/c1-25-10-11-27(23,24)22-8-3-4-16-14-21-9-7-15-12-17(26-2)5-6-18(15)20(21)13-19(16)22/h5-6,12,16,19-20H,3-4,7-11,13-14H2,1-2H3/t16-,19+,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.603	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229147 (CHEMBL348793) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc4OCOc4cc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H24N2O4S/c1-25(21,22)20-5-2-3-13-10-19-6-4-12-7-17-18(24-11-23-17)8-14(12)16(19)9-15(13)20/h7-8,13,15-16H,2-6,9-11H2,1H3/t13-,15-,16+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.646	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229143 (CHEMBL162971) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc4OCOc4cc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H24N2O4S/c1-25(21,22)20-5-2-3-13-10-19-6-4-12-7-17-18(24-11-23-17)8-14(12)16(19)9-15(13)20/h7-8,13,15-16H,2-6,9-11H2,1H3/t13-,15+,16+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228316 (CHEMBL62912) Show SMILES COc1ccc2C3CC4C(CCCN4S(C)(=O)=O)CN3CCc2c1 Show InChI InChI=1S/C18H26N2O3S/c1-23-15-5-6-16-13(10-15)7-9-19-12-14-4-3-8-20(24(2,21)22)17(14)11-18(16)19/h5-6,10,14,17-18H,3-4,7-9,11-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	0.661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description In vitro inhibition of Escherichia coli dihydrofolate reductase.				J Med Chem 32: 2034-6 (1989) BindingDB Entry DOI: 10.7270/Q2WH2S78
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229179 (Delequamine) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H26N2O3S/c1-23-15-5-6-16-13(10-15)7-9-19-12-14-4-3-8-20(24(2,21)22)17(14)11-18(16)19/h5-6,10,14,17-18H,3-4,7-9,11-12H2,1-2H3/t14-,17+,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229152 (CHEMBL349004) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(C)ccc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H26N2O2S/c1-13-5-6-16-14(10-13)7-9-19-12-15-4-3-8-20(23(2,21)22)17(15)11-18(16)19/h5-6,10,15,17-18H,3-4,7-9,11-12H2,1-2H3/t15-,17+,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.708	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229155 (CHEMBL164420) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)N(C)C Show InChI InChI=1S/C19H29N3O3S/c1-20(2)26(23,24)22-9-4-5-15-13-21-10-8-14-11-16(25-3)6-7-17(14)19(21)12-18(15)22/h6-7,11,15,18-19H,4-5,8-10,12-13H2,1-3H3/t15-,18-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229074 (CHEMBL163570) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)CCl Show InChI InChI=1S/C18H25ClN2O3S/c1-24-15-4-5-16-13(9-15)6-8-20-11-14-3-2-7-21(25(22,23)12-19)17(14)10-18(16)20/h4-5,9,14,17-18H,2-3,6-8,10-12H2,1H3/t14-,17-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229171 (CHEMBL411954) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)CCCC Show InChI InChI=1S/C20H30N2O2S/c1-2-3-13-25(23,24)22-11-6-8-17-15-21-12-10-16-7-4-5-9-18(16)20(21)14-19(17)22/h4-5,7,9,17,19-20H,2-3,6,8,10-15H2,1H3/t17-,19+,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229149 (CHEMBL159919) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C22H26N2O2S/c25-27(26,19-9-2-1-3-10-19)24-13-6-8-18-16-23-14-12-17-7-4-5-11-20(17)22(23)15-21(18)24/h1-5,7,9-11,18,21-22H,6,8,12-16H2/t18-,21+,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229178 (CHEMBL161278) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)c1cccs1 Show InChI InChI=1S/C21H26N2O3S2/c1-26-17-6-7-18-15(12-17)8-10-22-14-16-4-2-9-23(19(16)13-20(18)22)28(24,25)21-5-3-11-27-21/h3,5-7,11-12,16,19-20H,2,4,8-10,13-14H2,1H3/t16-,19-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229170 (CHEMBL348831) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C24H30N2O3S/c1-29-21-9-10-22-19(14-21)11-13-25-16-20-8-5-12-26(23(20)15-24(22)25)30(27,28)17-18-6-3-2-4-7-18/h2-4,6-7,9-10,14,20,23-24H,5,8,11-13,15-17H2,1H3/t20-,23-,24+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229141 (CHEMBL162965) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)C=C Show InChI InChI=1S/C19H26N2O3S/c1-3-25(22,23)21-9-4-5-15-13-20-10-8-14-11-16(24-2)6-7-17(14)19(20)12-18(15)21/h3,6-7,11,15,18-19H,1,4-5,8-10,12-13H2,2H3/t15-,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229146 (CHEMBL163290) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)CC Show InChI InChI=1S/C18H26N2O2S/c1-2-23(21,22)20-10-5-7-15-13-19-11-9-14-6-3-4-8-16(14)18(19)12-17(15)20/h3-4,6,8,15,17-18H,2,5,7,9-13H2,1H3/t15-,17+,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229077 (CHEMBL348726) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc4OCCOc4cc13)C2)S(C)(=O)=O Show InChI InChI=1S/C19H26N2O4S/c1-26(22,23)21-5-2-3-14-12-20-6-4-13-9-18-19(25-8-7-24-18)10-15(13)17(20)11-16(14)21/h9-10,14,16-17H,2-8,11-12H2,1H3/t14-,16+,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229079 (CHEMBL352278) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)CC(C)C Show InChI InChI=1S/C20H30N2O2S/c1-15(2)14-25(23,24)22-10-5-7-17-13-21-11-9-16-6-3-4-8-18(16)20(21)12-19(17)22/h3-4,6,8,15,17,19-20H,5,7,9-14H2,1-2H3/t17-,19+,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229148 (CHEMBL350388) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)CC(C)C Show InChI InChI=1S/C21H32N2O3S/c1-15(2)14-27(24,25)23-9-4-5-17-13-22-10-8-16-11-18(26-3)6-7-19(16)21(22)12-20(17)23/h6-7,11,15,17,20-21H,4-5,8-10,12-14H2,1-3H3/t17-,20+,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229072 (CHEMBL162841) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(C)(=O)=O Show InChI InChI=1S/C17H24N2O2S/c1-22(20,21)19-9-4-6-14-12-18-10-8-13-5-2-3-7-15(13)17(18)11-16(14)19/h2-3,5,7,14,16-17H,4,6,8-12H2,1H3/t14-,16+,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229134 (CHEMBL262446) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)N(C)C Show InChI InChI=1S/C18H27N3O2S/c1-19(2)24(22,23)21-10-5-7-15-13-20-11-9-14-6-3-4-8-16(14)18(20)12-17(15)21/h3-4,6,8,15,17-18H,5,7,9-13H2,1-2H3/t15-,17+,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229160 (CHEMBL355140) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)CCC Show InChI InChI=1S/C19H28N2O2S/c1-2-12-24(22,23)21-10-5-7-16-14-20-11-9-15-6-3-4-8-17(15)19(20)13-18(16)21/h3-4,6,8,16,18-19H,2,5,7,9-14H2,1H3/t16-,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229137 (CHEMBL350168) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H25FN2O2S/c23-18-7-9-19(10-8-18)28(26,27)25-12-3-5-17-15-24-13-11-16-4-1-2-6-20(16)22(24)14-21(17)25/h1-2,4,6-10,17,21-22H,3,5,11-15H2/t17-,21+,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229138 (CHEMBL162024) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C22H27N3O2S/c23-18-7-9-19(10-8-18)28(26,27)25-12-3-5-17-15-24-13-11-16-4-1-2-6-20(16)22(24)14-21(17)25/h1-2,4,6-10,17,21-22H,3,5,11-15,23H2/t17-,21+,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229150 (CHEMBL350393) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(=O)(=O)N(C)C Show InChI InChI=1S/C19H29N3O3S/c1-20(2)26(23,24)22-9-4-5-15-13-21-10-8-14-11-16(25-3)6-7-17(14)19(21)12-18(15)22/h6-7,11,15,18-19H,4-5,8-10,12-13H2,1-3H3/t15-,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229081 (CHEMBL162109) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cccc(OC)c13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H26N2O3S/c1-23-17-7-3-5-13-8-10-19-12-14-6-4-9-20(24(2,21)22)15(14)11-16(19)18(13)17/h3,5,7,14-16H,4,6,8-12H2,1-2H3/t14-,15+,16+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229139 (CHEMBL349777) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)CCOC Show InChI InChI=1S/C19H28N2O3S/c1-24-11-12-25(22,23)21-9-4-6-16-14-20-10-8-15-5-2-3-7-17(15)19(20)13-18(16)21/h2-3,5,7,16,18-19H,4,6,8-14H2,1H3/t16-,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229161 (CHEMBL443554) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)ccc13)C2)S(N)(=O)=O Show InChI InChI=1S/C17H25N3O3S/c1-23-14-4-5-15-12(9-14)6-8-19-11-13-3-2-7-20(24(18,21)22)16(13)10-17(15)19/h4-5,9,13,16-17H,2-3,6-8,10-11H2,1H3,(H2,18,21,22)/t13-,16+,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228640 (CHEMBL1203556) Show SMILES Cl.Cl.Fc1cccc2CN(CC3=NCCN3)CCc12 |t:9| Show InChI InChI=1S/C13H16FN3/c14-12-3-1-2-10-8-17(7-4-11(10)12)9-13-15-5-6-16-13/h1-3H,4-9H2,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to the alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]idazoxan as radioligand				J Med Chem 33: 596-600 (1990) BindingDB Entry DOI: 10.7270/Q2BK1FKZ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228625 (CHEMBL2448022) Show SMILES Cl.Cl.Clc1cccc2CN(CC3=NCCN3)Cc12 |t:9| Show InChI InChI=1S/C12H14ClN3/c13-11-3-1-2-9-6-16(7-10(9)11)8-12-14-4-5-15-12/h1-3H,4-8H2,(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to the alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]idazoxan as radioligand				J Med Chem 33: 596-600 (1990) BindingDB Entry DOI: 10.7270/Q2BK1FKZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50228703 (CHEMBL155823) Show SMILES Clc1cccc2CCN(CCCCN3C(=O)CC4(CCCC4)CC3=O)CCc12 Show InChI InChI=1S/C23H31ClN2O2/c24-20-7-5-6-18-8-14-25(15-9-19(18)20)12-3-4-13-26-21(27)16-23(17-22(26)28)10-1-2-11-23/h5-7H,1-4,8-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor in rat cerebral cortical membrane using [3H]-8-OH-DPAT as radioligand.				J Med Chem 33: 633-41 (1990) BindingDB Entry DOI: 10.7270/Q26T0PV7
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229163 (CHEMBL350144) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3cc(OC)c(Br)cc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H25BrN2O3S/c1-24-18-8-12-5-7-20-11-13-4-3-6-21(25(2,22)23)16(13)10-17(20)14(12)9-15(18)19/h8-9,13,16-17H,3-7,10-11H2,1-2H3/t13-,16-,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229144 (CHEMBL161070) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H25ClN2O2S/c23-18-7-9-19(10-8-18)28(26,27)25-12-3-5-17-15-24-13-11-16-4-1-2-6-20(16)22(24)14-21(17)25/h1-2,4,6-10,17,21-22H,3,5,11-15H2/t17-,21+,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229157 (CHEMBL346462) Show SMILES [H][C@]12CCCN([C@]1([H])C[C@]1([H])N(CCc3c(Br)c(OC)ccc13)C2)S(C)(=O)=O Show InChI InChI=1S/C18H25BrN2O3S/c1-24-17-6-5-13-14(18(17)19)7-9-20-11-12-4-3-8-21(25(2,22)23)15(12)10-16(13)20/h5-6,12,15-16H,3-4,7-11H2,1-2H3/t12-,15-,16+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228639 (CHEMBL1203560) Show SMILES Cl.Cl.Fc1cccc2CCN(CC3=NCCN3)Cc12 |t:10| Show InChI InChI=1S/C13H16FN3/c14-12-3-1-2-10-4-7-17(8-11(10)12)9-13-15-5-6-16-13/h1-3H,4-9H2,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to the alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]idazoxan as radioligand				J Med Chem 33: 596-600 (1990) BindingDB Entry DOI: 10.7270/Q2BK1FKZ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228635 (CHEMBL2448029) Show SMILES Cl.Cl.Clc1cccc2CCN(CC3=NCCN3)Cc12 |t:10| Show InChI InChI=1S/C13H16ClN3/c14-12-3-1-2-10-4-7-17(8-11(10)12)9-13-15-5-6-16-13/h1-3H,4-9H2,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity was determined against alpha-2 adrenergic receptor of rat cerebral cortex using [3H]idazoxan as radioligand				J Med Chem 33: 596-600 (1990) BindingDB Entry DOI: 10.7270/Q2BK1FKZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50228680 (CHEMBL345810) Show SMILES [H][C@@]12CCCc3ccc(Cl)c(CCN(C)C1)c23 Show InChI InChI=1S/C14H18ClN/c1-16-8-7-12-13(15)6-5-10-3-2-4-11(9-16)14(10)12/h5-6,11H,2-4,7-9H2,1H3/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor in rat cerebral cortical membrane using [3H]-8-OH-DPAT as radioligand.				J Med Chem 33: 633-41 (1990) BindingDB Entry DOI: 10.7270/Q26T0PV7
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229168 (CHEMBL350105) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(O)ccc13)C2)S(C)(=O)=O Show InChI InChI=1S/C17H24N2O3S/c1-23(21,22)19-7-2-3-13-11-18-8-6-12-9-14(20)4-5-15(12)17(18)10-16(13)19/h4-5,9,13,16-17,20H,2-3,6-8,10-11H2,1H3/t13-,16+,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229070 (CHEMBL159802) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc4OCOc4cc13)C2)S(=O)(=O)CC(C)C Show InChI InChI=1S/C21H30N2O4S/c1-14(2)12-28(24,25)23-6-3-4-16-11-22-7-5-15-8-20-21(27-13-26-20)9-17(15)19(22)10-18(16)23/h8-9,14,16,18-19H,3-7,10-13H2,1-2H3/t16-,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229166 (CHEMBL435057) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(=O)(=O)CCO Show InChI InChI=1S/C18H26N2O3S/c21-10-11-24(22,23)20-8-3-5-15-13-19-9-7-14-4-1-2-6-16(14)18(19)12-17(15)20/h1-2,4,6,15,17-18,21H,3,5,7-13H2/t15-,17+,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50026636 (17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic...) Show SMILES COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]yohimbine as radioligand				J Med Chem 33: 596-600 (1990) BindingDB Entry DOI: 10.7270/Q2BK1FKZ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50026636 (17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic...) Show SMILES COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50019848 (2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...) Show SMILES C1CN=C(N1)C1COc2ccccc2O1 |c:2| Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to the alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]idazoxan as radioligand				J Med Chem 33: 596-600 (1990) BindingDB Entry DOI: 10.7270/Q2BK1FKZ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228638 (CHEMBL2448025) Show SMILES Cl.Cl.Clc1ccc(Cl)c2CN(CC3=NCCN3)CCc12 |t:10| Show InChI InChI=1S/C13H15Cl2N3/c14-11-1-2-12(15)10-7-18(6-3-9(10)11)8-13-16-4-5-17-13/h1-2H,3-8H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to the alpha-2 adrenergic receptor of rat cerebral cortex assayed using [3H]idazoxan as radioligand				J Med Chem 33: 596-600 (1990) BindingDB Entry DOI: 10.7270/Q2BK1FKZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50228679 (CHEMBL160918) Show SMILES Clc1ccc2CCCC3CN(CCCCN4C(=O)CC5(CCCC5)CC4=O)CCc1c23 Show InChI InChI=1S/C26H35ClN2O2/c27-22-9-8-19-6-5-7-20-18-28(15-10-21(22)25(19)20)13-3-4-14-29-23(30)16-26(17-24(29)31)11-1-2-12-26/h8-9,20H,1-7,10-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor in rat cerebral cortical membrane using [3H]-8-OH-DPAT as radioligand.				J Med Chem 33: 633-41 (1990) BindingDB Entry DOI: 10.7270/Q26T0PV7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50228695 (CHEMBL156585) Show SMILES Clc1ccc2CCCC3CN(CC=C)CCc1c23 Show InChI InChI=1S/C16H20ClN/c1-2-9-18-10-8-14-15(17)7-6-12-4-3-5-13(11-18)16(12)14/h2,6-7,13H,1,3-5,8-11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor in rat cerebral cortical membrane using [3H]-8-OH-DPAT as radioligand.				J Med Chem 33: 633-41 (1990) BindingDB Entry DOI: 10.7270/Q26T0PV7
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM66983 (6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazep...) Show SMILES CN1CCc2cccc(Cl)c2CC1 Show InChI InChI=1S/C11H14ClN/c1-13-7-5-9-3-2-4-11(12)10(9)6-8-13/h2-4H,5-8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor in rat cerebral cortical membrane using [3H]yohimbine as radioligand.				J Med Chem 33: 633-41 (1990) BindingDB Entry DOI: 10.7270/Q26T0PV7
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229164 (CHEMBL161531) Show SMILES [H][C@]12CCCN([C@@]1([H])C[C@]1([H])N(CCc3cc(OC)c(OC)cc13)C2)S(=O)(=O)CC(C)C Show InChI InChI=1S/C22H34N2O4S/c1-15(2)14-29(25,26)24-8-5-6-17-13-23-9-7-16-10-21(27-3)22(28-4)11-18(16)20(23)12-19(17)24/h10-11,15,17,19-20H,5-9,12-14H2,1-4H3/t17-,19+,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane				J Med Chem 34: 705-17 (1991) BindingDB Entry DOI: 10.7270/Q2MW2KBF
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50228685 (CHEMBL1202289) Show SMILES Br.CN1CCc2c3C(CCc3ccc2Cl)C1 Show InChI InChI=1S/C13H16ClN.BrH/c1-15-7-6-11-12(14)5-4-9-2-3-10(8-15)13(9)11;/h4-5,10H,2-3,6-8H2,1H3;1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor in rat cerebral cortical membrane using [3H]yohimbine as radioligand.				J Med Chem 33: 633-41 (1990) BindingDB Entry DOI: 10.7270/Q26T0PV7
					More data for this Ligand-Target Pair

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