BindingDB PrimarySearch

Found 18 hits with Last Name = 'marzec' and Initial = 'u'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor VII (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	0.350	-53.4	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180400 (2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM14898 (2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-5-(...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180405 (2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180403 (2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180404 (2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-(2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180401 (2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180406 (2-[5'-aminomethyl-5-(5-carbamimidoyl-1H-benzoimida...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180407 (2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50180402 (2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to F7a/TF complex				Bioorg Med Chem Lett 16: 2037-41 (2006) Article DOI: 10.1016/j.bmcl.2005.12.059 BindingDB Entry DOI: 10.7270/Q2639PBP
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	87	-39.9	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	114	-39.2	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	1.20E+3	-33.5	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	>3.40E+3	>-30.9	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	>3.50E+3	>-30.8	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	3.60E+3	-30.8	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	>3.90E+3	>-30.6	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair
Serine protease 1 (Bos taurus (bovine))	BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	4.00E+3	-30.5	n/a	n/a	n/a	n/a	n/a	7.8	22
Genentech					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3
Genentech					More data for this Ligand-Target Pair