Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186127 (CHEMBL378408 | N-[(R)-2-{4-[2-(acetyl-ethyl-amino)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186127 (CHEMBL378408 | N-[(R)-2-{4-[2-(acetyl-ethyl-amino)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494356 (CHEMBL3088070) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186127 (CHEMBL378408 | N-[(R)-2-{4-[2-(acetyl-ethyl-amino)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186131 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(1-cyclohexyl-2...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186121 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(1-cyclopentyl-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186125 (CHEMBL377825 | N-((R)-3-(4-chlorophenyl)-1-(4-(3-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186128 (CHEMBL209990 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186128 (CHEMBL209990 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186124 (CHEMBL410087 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186124 (CHEMBL410087 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186138 (CHEMBL425609 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088223 (CHEMBL61751 | E-2-Amino-4-(3-naphthalen-1-yl-allyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088197 (CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;... | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088197 (CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 5 (Homo sapiens (Human)) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Ability of the compound to bind to Ionotropic glutamate receptor kainate (kainate 2) was evaluated. | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Ability of the compound to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluated | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186122 (CHEMBL377313 | N-((R)-3-(4-chlorophenyl)-1-(4-(3-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088229 (2-Amino-4-prop-2-ynyl-pentanedioic acid | CHEMBL59...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 11.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186120 (CHEMBL380391 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186135 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(3-cyclohexyl-1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186119 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(1-cycloheptyl-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186133 (3,4-Dihydro-1H-isoquinoline-2-carboxylic acid ((R)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;... | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50139027 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptor | Bioorg Med Chem Lett 15: 4973-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.018 BindingDB Entry DOI: 10.7270/Q2HT2NWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50174056 (CHEMBL381015 | Diethyl-[(S)-2-(2-fluoro-phenyl)-2-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptor | Bioorg Med Chem Lett 15: 4973-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.018 BindingDB Entry DOI: 10.7270/Q2HT2NWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;... | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186132 (CHEMBL378411 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186132 (CHEMBL378411 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186126 (CHEMBL379051 | N-((R)-3-(4-chlorophenyl)-1-(4-(2,6...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50174055 (CHEMBL198379 | Diethyl-[2-(2-fluoro-phenyl)-2-(4-m...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptor | Bioorg Med Chem Lett 15: 4973-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.018 BindingDB Entry DOI: 10.7270/Q2HT2NWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50494356 (CHEMBL3088070) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]ATPA from human Gluk1 receptor | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50177561 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088212 (2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186134 (CHEMBL209559 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088228 (2-Amino-4-but-2-ynyl-pentanedioic acid | CHEMBL620...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 28.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088203 (CHEMBL301915 | E-2-Amino-4-[3-(4-bromo-phenyl)-all...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088216 (CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088216 (CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088235 (CHEMBL300368 | E-2-Amino-4-[3-(4-methylsulfanyl-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50091477 ((S)-2-Amino-4-cyclopentylidene-pentanedioic acid |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50186130 (CHEMBL211078 | N-((R)-3-(4-chlorophenyl)-1-(4-(dic...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells | Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human)) | BDBM50088224 (CHEMBL305346 | E-2-Amino-4-[3-(3-methoxy-phenyl)-a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50174062 (CHEMBL371896 | Diethyl-[2-(4-methyl-piperazin-1-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptor | Bioorg Med Chem Lett 15: 4973-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.018 BindingDB Entry DOI: 10.7270/Q2HT2NWT | |||||||||||
More data for this Ligand-Target Pair |
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