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Compile Data Set for Download or QSAR

Found 3 hits with Last Name = 'melody' and Initial = 'n'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50258529
PNG
(CHEMBL449158 | bryostatin 1)
Show SMILES CCC\C=C\C=C\C(=O)O[C@H]1\C(C[C@H]2C[C@@H](OC(=O)C[C@H](O)C[C@@H]3C[C@H](OC(C)=O)C(C)(C)[C@](O)(C[C@@H]4C\C(C[C@@H](O4)\C=C\C(C)(C)[C@]1(O)O2)=C\C(=O)OC)O3)[C@@H](C)O)=C\C(=O)OC |r,t:43|
Show InChI InChI=1S/C47H68O17/c1-10-11-12-13-14-15-39(51)62-43-31(22-41(53)58-9)21-34-25-37(28(2)48)61-42(54)24-32(50)23-35-26-38(59-29(3)49)45(6,7)46(55,63-35)27-36-19-30(20-40(52)57-8)18-33(60-36)16-17-44(4,5)47(43,56)64-34/h12-17,20,22,28,32-38,43,48,50,55-56H,10-11,18-19,21,23-27H2,1-9H3/b13-12+,15-14+,17-16+,30-20+,31-22+/t28-,32-,33+,34+,35-,36+,37-,38+,43+,46+,47-/m1/s1
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Article
PubMed
0.480n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assay


J Nat Prod 78: 896-900 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00094
BindingDB Entry DOI: 10.7270/Q2ZK5JD2
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50090080
PNG
(CHEMBL3581528)
Show SMILES [H][C@]12C[C@H](OC(C)=O)C(C)(C)[C@](O)(CCOC(=O)\C=C\C(C)(C)[C@]3(O)O[C@@]([H])(C\C(=C/C(=O)OC)[C@@H]3OC(=O)CCCCCCC)C[C@@H](O)[C@@H](C)OC(=O)C[C@H](O)C1)O2 |r,t:18|
Show InChI InChI=1S/C41H64O16/c1-9-10-11-12-13-14-34(46)55-37-27(20-35(47)51-8)19-29-23-31(44)25(2)53-36(48)22-28(43)21-30-24-32(54-26(3)42)39(6,7)40(49,56-30)17-18-52-33(45)15-16-38(4,5)41(37,50)57-29/h15-16,20,25,28-32,37,43-44,49-50H,9-14,17-19,21-24H2,1-8H3/b16-15+,27-20+/t25-,28-,29+,30-,31-,32+,37+,40+,41-/m1/s1
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14n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assay


J Nat Prod 78: 896-900 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00094
BindingDB Entry DOI: 10.7270/Q2ZK5JD2
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50090081
PNG
(CHEMBL3581527)
Show SMILES [H][C@@]12C[C@]3([H])CC(=O)O[C@@]3(O1)C(=O)C(C)(C)\C=C\[C@@]1([H])C\C(C[C@@]([H])(C[C@]3(O)O[C@@]([H])(C[C@H](OC(=O)C(C)(C)C)C3(C)C)C[C@@H](O)CC(=O)O[C@H](C)[C@H](O)C2)O1)=C/C(=O)OC |r,t:18|
Show InChI InChI=1S/C41H60O15/c1-22-30(43)19-27-15-24-16-34(46)56-41(24,55-27)35(47)38(5,6)11-10-26-12-23(14-32(44)50-9)13-29(52-26)21-40(49)39(7,8)31(53-36(48)37(2,3)4)20-28(54-40)17-25(42)18-33(45)51-22/h10-11,14,22,24-31,42-43,49H,12-13,15-21H2,1-9H3/b11-10+,23-14+/t22-,24-,25-,26+,27+,28-,29+,30-,31+,40+,41-/m1/s1
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21n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assay


J Nat Prod 78: 896-900 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00094
BindingDB Entry DOI: 10.7270/Q2ZK5JD2
More data for this
Ligand-Target Pair