Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50135460 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-4'-fluoro-5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50135453 ((2E,4E,6Z)-7-[2-(2,2-Difluoro-ethoxy)-3-isopropyl-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133128 (5-{2-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against Rhizopus chinensis pepsin | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Rattus norvegicus) | BDBM50133119 (5-{2-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129723 (7-[2-(2-Fluoro-ethoxy)-3,5-diisopropyl-phenyl]-3-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50135462 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3'-fluoro-5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129719 (7-(3,5-Di-tert-butyl-2-methoxy-phenyl)-3-methyl-oc...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129717 (7-(3,5-Diisopropyl-2-methoxy-phenyl)-3-methyl-octa...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133119 (5-{2-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129720 ((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Rattus norvegicus) | BDBM50133118 (5-{3-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50146331 ((E)-3-{3-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace [3H]-9-cis-RA from Retinoid X receptor alpha in CV-1 cells | Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50146327 ((E)-3-[3-(3,5-Di-tert-butyl-2-propoxy-phenyl)-1H-i...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace [3H]-9-cis-RA from Retinoid X receptor alpha in CV-1 cells | Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133114 (5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-gamma (Rattus norvegicus) | BDBM50133128 (5-{2-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-gamma was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133116 ((2E,4E)-5-{3-[3,5-Di-tert-butyl-2-(3,3-difluoro-pr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro transcriptional activation in CV-1 cells expressing RXR-alpha | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129726 ((2E,4E,6Z)-7-(2-Ethoxy-3,5-diisopropyl-phenyl)-3-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace [3H]-9-cis-RA from Retinoid X receptor alpha in CV-1 cells | Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129731 (7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phenyl]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129726 ((2E,4E,6Z)-7-(2-Ethoxy-3,5-diisopropyl-phenyl)-3-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129722 (7-[3,5-Bis-(1,1-dimethyl-propyl)-2-ethoxy-phenyl]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129730 (7-[3,5-Bis-(1,1-dimethyl-propyl)-2-methoxy-phenyl]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133118 (5-{3-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50135450 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-2'-fluoro-5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Homo sapiens (Human)) | BDBM50135461 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3',5'-difluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Displacement of [3H]-9-cis-RA from RXR beta receptor in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Rattus norvegicus) | BDBM50133128 (5-{2-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-gamma (Rattus norvegicus) | BDBM50133118 (5-{3-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-gamma was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50135461 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3',5'-difluo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50146328 ((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(3-fluoro-propox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cells | Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129720 ((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of 3[H]-9-cis-retinoic acid binding to Retinoic acid receptor RXR-alpha expressed in CV-1 cells | Bioorg Med Chem Lett 13: 3191-5 (2003) BindingDB Entry DOI: 10.7270/Q2736Q9T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-gamma (Homo sapiens (Human)) | BDBM50135461 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3',5'-difluo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR gamma receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Rattus norvegicus) | BDBM50133127 (5-{3-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-gamma (Homo sapiens (Human)) | BDBM50135462 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3'-fluoro-5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR gamma receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50141599 ((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2,2-trifluoro-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50129720 ((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50141595 ((E)-3-{4-[3,5-Di-tert-butyl-2-(3-fluoro-propoxy)-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Antagonist activity for Retinoic X receptor alpha in CV1 cells | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129720 ((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50032671 (6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPH...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50135452 ((2E,4E,6Z)-7-[2-(2,2-Difluoro-ethoxy)-5-furan-2-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129724 (7-(3,5-Diisopropyl-2-propoxy-phenyl)-3-methyl-octa...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129733 (7-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-phen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133121 (5-{3-[3-tert-Butyl-2-(2,2-difluoro-ethoxy)-5-ethyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50146337 ((E)-3-[3-(2-Butoxy-3,5-di-tert-butyl-phenyl)-1H-in...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace [3H]-9-cis-RA from Retinoid X receptor alpha in CV-1 cells | Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (RAT) | BDBM50133127 (5-{3-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against R. chinensis pepsin | J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50132579 ((2E,4E,6Z)-7-(2-Butoxy-3,5-di-tert-butyl-phenyl)-3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Synergistic activation of BRL49653 mediated PPAR gamma and retinoid X receptor alpha expressed in CV-1 cell transcriptional activation assay | Bioorg Med Chem Lett 13: 3191-5 (2003) BindingDB Entry DOI: 10.7270/Q2736Q9T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Homo sapiens (Human)) | BDBM50135453 ((2E,4E,6Z)-7-[2-(2,2-Difluoro-ethoxy)-3-isopropyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Displacement of [3H]-9-cis-RA from RXR beta receptor in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Homo sapiens (Human)) | BDBM50135460 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-4'-fluoro-5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Displacement of [3H]-9-cis-RA from RXR beta receptor in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129725 ((2E,4E,6Z)-7-(2-Butoxy-3,5-diisopropyl-phenyl)-3-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cells | Bioorg Med Chem Lett 14: 2759-63 (2004) Article DOI: 10.1016/j.bmcl.2004.03.073 BindingDB Entry DOI: 10.7270/Q2513XNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50129725 ((2E,4E,6Z)-7-(2-Butoxy-3,5-diisopropyl-phenyl)-3-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligand | J Med Chem 46: 2683-96 (2003) Article DOI: 10.1021/jm020340q BindingDB Entry DOI: 10.7270/Q27H1HZ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-beta (Homo sapiens (Human)) | BDBM50129720 ((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Displacement of [3H]-9-cis-RA from RXR beta receptor in CV-1 cells | Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 1642 total ) | Next | Last >> |