Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F550C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R179C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F554C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R176C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T549C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T553C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T552C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K548C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T556C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K555C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F550C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R551C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T553C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T180C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R176C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T180C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K178C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,A177C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 4.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T556C] (Rattus norvegicus (Rat)) | BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 4.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F550C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.556 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T552C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.438 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.440 | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R176C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T180C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 1.11 | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F550C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 1.15 | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T553C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 1.02 | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T556C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T553C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.548 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K548C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.555 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F554C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.583 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.555 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K555C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.553 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T556C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.462 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.403 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R176C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.484 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,A177C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.521 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K178C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.499 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R179C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.493 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T180C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.751 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R551C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.524 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T549C] (Rattus norvegicus (Rat)) | BDBM214800 (N-methylscopolamine (NMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 0.564 | n/a | n/a | n/a | 7.4 | n/a |
National Institutes of Health | Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing... | J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C | |||||||||||
More data for this Ligand-Target Pair |