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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555110 (3-[(3-fluorophenyl)amino]-2-[3-(2-hydroxy-2-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.0720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555112 (3-[(3-fluorophenyl)amino]-2-[3-(2-methoxy-2-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.0720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555116 (3-[(3,5-difluorophenyl)amino]-2-[3-(2-methoxy-2-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.0720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555115 (3-[(3,5-difluorophenyl)amino]-2-[3-(2-methoxyethox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.0720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555118 (3-[(2-bromo-3-fluorophenyl)amino]-2-[3-(2-methoxye...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555136 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0970 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555137 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0990 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555123 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 0.113 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555124 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555110 (3-[(3-fluorophenyl)amino]-2-[3-(2-hydroxy-2-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.131 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555122 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.138 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555127 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.138 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555126 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.149 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555125 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.155 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555137 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.161 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555128 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.176 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555123 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 0.177 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555136 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.209 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555122 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.212 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555112 (3-[(3-fluorophenyl)amino]-2-[3-(2-methoxy-2-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.212 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555127 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.213 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555118 (3-[(2-bromo-3-fluorophenyl)amino]-2-[3-(2-methoxye...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.218 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555117 (3-{[2-(difluoromethoxy)phenyl]amino}-2-[3-(2-metho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555125 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.239 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555135 (3-[(3,4-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.246 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555129 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.259 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555132 (3-[(2-ethoxy-3-fluorophenyl)amino]-2-[3-(2-methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.268 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555103 (2-[3-(benzyloxy)pyridin-4-yl]-3-[(3-fluorophenyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555124 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555128 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.309 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555114 (3-[(3-fluorophenyl)amino]-2-(3-{[(2S)-1-methylpyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555126 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.322 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555129 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.342 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555121 (3-{[2-(2,2-difluoroethyl)phenyl]amino}-2-[3-(2-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.489 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555130 (3-[(3-fluoro-2-hydroxyphenyl)amino]-2-[3-(2-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.541 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555130 (3-[(3-fluoro-2-hydroxyphenyl)amino]-2-[3-(2-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.634 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555113 (3-[(3-fluorophenyl)amino]-2-{3-[2-methyl-2-(morpho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.718 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555134 (US11339157, Example 28) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.738 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555101 (2-[3-(2-methoxyethoxy)pyridin-4-yl]-3-(phenylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.779 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555132 (3-[(2-ethoxy-3-fluorophenyl)amino]-2-[3-(2-methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.943 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555131 (3-[(2-ethoxy-3-fluorophenyl)amino]-2-[3-(2-methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.09 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555121 (3-{[2-(2,2-difluoroethyl)phenyl]amino}-2-[3-(2-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555111 (2-{3-[2-(dimethylamino)ethoxy]pyridin-4-yl}-3-[(3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM459773 (3,3-dimethyl-2-{2-[(3R)-3-methylmorpholin-4-yl]-8-...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer AG Curated by ChEMBL | Assay Description Inhibition of 5'-TAMRA-labeled tracer 3',6'-bis(dimethylamino)-N-(4-{[2(1H-indol-4-yl)-6-(morpholin-4-yl)-pyrimidin-4-yl]amino}butyl)-3-oxo-3H-spiro[... | J Med Chem 63: 7293-7325 (2020) Article DOI: 10.1021/acs.jmedchem.0c00369 BindingDB Entry DOI: 10.7270/Q29C71ZT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555133 (US11339157, Example 27) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555120 (2-[3-(2-methoxyethoxy)pyridin-4-yl]-3-{[2-(trifluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.66 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM50427326 (CHEMBL2325697) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer AG Curated by ChEMBL | Assay Description Inhibition of 5'-TAMRA-labeled tracer 3',6'-bis(dimethylamino)-N-(4-{[2(1H-indol-4-yl)-6-(morpholin-4-yl)-pyrimidin-4-yl]amino}butyl)-3-oxo-3H-spiro[... | J Med Chem 63: 7293-7325 (2020) Article DOI: 10.1021/acs.jmedchem.0c00369 BindingDB Entry DOI: 10.7270/Q29C71ZT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human)) | BDBM555102 (2-[3-(3,3-dimethylbutoxy)pyridin-4-yl]-3-[(3-fluor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.99 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM268208 (US10772893, Example 241 | US11529356, Example 241 ...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.06 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo... | US Patent US9549932 (2017) BindingDB Entry DOI: 10.7270/Q27S7QSC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATR-interacting protein/Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM268208 (US10772893, Example 241 | US11529356, Example 241 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.06 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474FQK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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