Compile Data Set for Download or QSAR

Found 18186 hits with Last Name = 'moreno' and Initial = 'da'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret [G810S] (Homo sapiens (Human))	BDBM576988 (US11472802, Example 8) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM576988 (US11472802, Example 8) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM576988 (US11472802, Example 8) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [V804M] (Homo sapiens (Human))	BDBM576988 (US11472802, Example 8) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [G810R] (Homo sapiens (Human))	BDBM576988 (US11472802, Example 8) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577053 (US11472802, Example 58) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2c[nH]cn2)c2c(N)nccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577053 (US11472802, Example 58) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2c[nH]cn2)c2c(N)nccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577046 (7-chloro-3-(5-cyclopropyl- 4-(1H-pyrazol-3- yl)iso...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc[nH]n2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577046 (7-chloro-3-(5-cyclopropyl- 4-(1H-pyrazol-3- yl)iso...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc[nH]n2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577063 (1-(3-(4-amino-7-chloro-1- isopropyl-1H-pyrazolo[4,...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2N2CCN(C)C2=O)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577049 (US11472802, Example 55) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577050 (7-chloro-3-(5- cyclopropyl-4-(1H- imidazol-4- yl)i...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2c[nH]cn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577049 (US11472802, Example 55) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577045 (US11472802, Example 51) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)[nH]n2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [V804M] (Homo sapiens (Human))	BDBM577049 (US11472802, Example 55) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577050 (7-chloro-3-(5- cyclopropyl-4-(1H- imidazol-4- yl)i...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2c[nH]cn2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM597662 (US11603374, Example 17) Show SMILES Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z323KZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM576996 (US11472802, Example 11) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(F)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM576996 (US11472802, Example 11) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(F)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577026 (7-chloro-3-(5-cyclopropyl-4-(4- methylpyridin-2-yl...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)ccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577061 (US11472802, Example 65) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2N2CCC2=O)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577063 (1-(3-(4-amino-7-chloro-1- isopropyl-1H-pyrazolo[4,...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2N2CCN(C)C2=O)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577064 (US11472802, Example 68) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(F)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577064 (US11472802, Example 68) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(F)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577066 (3-(5-cyclopropyl- 4-(1H-pyrazol-3- yl)isoxazol-3- ...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc[nH]n2)c2c(N)ncc(F)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577025 (7-chloro-3-(5-cyclopropyl-4- (pyrazin-2-yl)isoxazo...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cnccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577061 (US11472802, Example 65) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2N2CCC2=O)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM565148 (US11414404, Ex. # 25 | US11634409, Example 25) Show SMILES Cc1c(Nc2c(F)ccc(NS(=O)(=O)c3cc(F)ccc3F)c2Cl)ccc2ncn(C)c(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged “tracer” bound to B-Raf via TR-FRET from...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JD511G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM565148 (US11414404, Ex. # 25 | US11634409, Example 25) Show SMILES Cc1c(Nc2c(F)ccc(NS(=O)(=O)c3cc(F)ccc3F)c2Cl)ccc2ncn(C)c(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2FT8R02
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577045 (US11472802, Example 51) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)[nH]n2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577067 (3-(5-cyclopropyl- 4-(5-methyl-1H- pyrazol-3-yl) is...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)[nH]n2)c2c(N)ncc(F)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM597647 (US11603374, Example 2) Show SMILES CC(C)n1cc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncnc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z323KZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM597647 (US11603374, Example 2) Show SMILES CC(C)n1cc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncnc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z323KZ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human))	BDBM193676 (US9670208, Example 295 4-(3-(cyclopropylmethyl)-[1...) Show SMILES Cn1nccc1Nc1cc(ccn1)-c1ccn2c(CC3CC3)nnc2c1 Show InChI InChI=1S/C19H19N7/c1-25-17(5-8-21-25)22-16-11-14(4-7-20-16)15-6-9-26-18(10-13-2-3-13)23-24-19(26)12-15/h4-9,11-13H,2-3,10H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.3	n/a
Array BioPharma Inc.; Genentech, Inc. US Patent					Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...				US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577029 (7-chloro-3-(5-cyclopropyl-4-(5- methylpyridin-2-yl...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(C)cn2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577062 (1-(3-(4-amino-7-chloro-1- isopropyl-1H-pyrazolo[4,...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2N2CCCC2=O)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [V804M] (Homo sapiens (Human))	BDBM577063 (1-(3-(4-amino-7-chloro-1- isopropyl-1H-pyrazolo[4,...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2N2CCN(C)C2=O)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577066 (3-(5-cyclopropyl- 4-(1H-pyrazol-3- yl)isoxazol-3- ...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc[nH]n2)c2c(N)ncc(F)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577025 (7-chloro-3-(5-cyclopropyl-4- (pyrazin-2-yl)isoxazo...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cnccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577026 (7-chloro-3-(5-cyclopropyl-4-(4- methylpyridin-2-yl...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)ccn2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [V804M] (Homo sapiens (Human))	BDBM576996 (US11472802, Example 11) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(F)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM565192 (US11414404, Ex. # 69 | US11634409, Example 69) Show SMILES CCCS(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn(C)c(=O)c3c2C)c1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged “tracer” bound to B-Raf via TR-FRET from...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JD511G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM565192 (US11414404, Ex. # 69 | US11634409, Example 69) Show SMILES CCCS(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn(C)c(=O)c3c2C)c1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2FT8R02
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577047 (7-chloro-3-(5-cyclopropyl- 4-(1-methyl-1H-pyrazol-...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccn(C)n2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM577047 (7-chloro-3-(5-cyclopropyl- 4-(1-methyl-1H-pyrazol-...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccn(C)n2)c2c(N)ncc(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577048 (7-chloro-3-(5-cyclopropyl- 4-(1-ethyl-1H-pyrazol-3...) Show SMILES CCn1ccc(n1)-c1c(noc1C1CC1)-c1nn(C(C)C)c2c(Cl)cnc(N)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM597673 (US11603374, Example 28) Show SMILES Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)[C@@H]1C[C@H](CO)C1 |r,wU:18.21,20.24,(-2.78,4.69,;-3.17,3.2,;-4.68,2.88,;-5.16,1.42,;-4.13,.27,;-2.62,.59,;-1.37,-.31,;-.13,.59,;-.6,2.06,;.17,3.39,;1.71,3.39,;2.18,4.85,;.94,5.76,;-.31,4.85,;3.67,5.25,;5.16,4.85,;4.76,6.34,;-2.14,2.06,;-1.37,-1.85,;-2.46,-2.94,;-1.37,-4.03,;-1.37,-5.57,;-.04,-6.34,;-.29,-2.94,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z323KZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM597673 (US11603374, Example 28) Show SMILES Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)[C@@H]1C[C@H](CO)C1 |r,wU:18.21,20.24,(-2.78,4.69,;-3.17,3.2,;-4.68,2.88,;-5.16,1.42,;-4.13,.27,;-2.62,.59,;-1.37,-.31,;-.13,.59,;-.6,2.06,;.17,3.39,;1.71,3.39,;2.18,4.85,;.94,5.76,;-.31,4.85,;3.67,5.25,;5.16,4.85,;4.76,6.34,;-2.14,2.06,;-1.37,-1.85,;-2.46,-2.94,;-1.37,-4.03,;-1.37,-5.57,;-.04,-6.34,;-.29,-2.94,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z323KZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [M918T] (Homo sapiens (Human))	BDBM597674 (US11603374, Example 29) Show SMILES Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)[C@H]1C[C@H](CO)C1 |r,wU:18.21,wD:20.24,(-2.78,4.69,;-3.17,3.2,;-4.68,2.88,;-5.16,1.42,;-4.13,.27,;-2.62,.59,;-1.37,-.31,;-.13,.59,;-.6,2.06,;.17,3.39,;1.71,3.39,;2.18,4.85,;.94,5.76,;-.31,4.85,;3.67,5.25,;5.16,4.85,;4.76,6.34,;-2.14,2.06,;-1.37,-1.85,;-.29,-2.94,;-1.37,-4.03,;-1.37,-5.57,;-.04,-6.34,;-2.46,-2.94,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z323KZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM577029 (7-chloro-3-(5-cyclopropyl-4-(5- methylpyridin-2-yl...) Show SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(C)cn2)c2c(N)ncc(Cl)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q22N55HG
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 18186 total )  |  Next  |  Last  >>

Jump to: