Found 147 hits with Last Name = 'moroni' and Initial = 'f' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407819
(CHEMBL2115152)Show SMILES N[C@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030627
((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15) | PDB
UniProtKB/SwissProt
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
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Similars
| PDB Article PubMed
| 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards mGluR1a was determined |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407823
(CHEMBL2114116)Show SMILES N[C@@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407827
(CHEMBL2115160)Show SMILES N[C@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407824
(CHEMBL2114115)Show SMILES N[C@@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407822
(CHEMBL2114112)Show SMILES N[C@@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407829
(CHEMBL2115153)Show SMILES N[C@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407830
(CHEMBL2115157)Show SMILES N[C@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407825
(CHEMBL2114110)Show SMILES N[C@H]([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407821
(CHEMBL2115151)Show SMILES N[C@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407825
(CHEMBL2114110)Show SMILES N[C@H]([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407831
(CHEMBL2115156)Show SMILES N[C@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407826
(CHEMBL2114105)Show SMILES N[C@@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407828
(CHEMBL2114106)Show SMILES N[C@@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407818
(CHEMBL2114109)Show SMILES N[C@@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407820
(CHEMBL2115159)Show SMILES N[C@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity towards metabotropic glutamate receptor mGluR1 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407822
(CHEMBL2114112)Show SMILES N[C@@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407824
(CHEMBL2114115)Show SMILES N[C@@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407828
(CHEMBL2114106)Show SMILES N[C@@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407823
(CHEMBL2114116)Show SMILES N[C@@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407820
(CHEMBL2115159)Show SMILES N[C@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m1/s1 | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407827
(CHEMBL2115160)Show SMILES N[C@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m0/s1 | PDB
UniProtKB/SwissProt
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| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407825
(CHEMBL2114110)Show SMILES N[C@H]([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407818
(CHEMBL2114109)Show SMILES N[C@@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407830
(CHEMBL2115157)Show SMILES N[C@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407831
(CHEMBL2115156)Show SMILES N[C@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407826
(CHEMBL2114105)Show SMILES N[C@@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407819
(CHEMBL2115152)Show SMILES N[C@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407829
(CHEMBL2115153)Show SMILES N[C@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407821
(CHEMBL2115151)Show SMILES N[C@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| >2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Kynurenine 3-monooxygenase
(Rattus norvegicus) | BDBM50083950
((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)Show SMILES N[C@@H](CC(=O)c1cccc(c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C10H10N2O5/c11-8(10(14)15)5-9(13)6-2-1-3-7(4-6)12(16)17/h1-4,8H,5,11H2,(H,14,15)/t8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested for inhibitory activity against kynurenine 3-hydroxylase |
Bioorg Med Chem Lett 5: 1451-1454 (1995)
Article DOI: 10.1016/0960-894X(95)00255-R BindingDB Entry DOI: 10.7270/Q2PR7VZZ |
More data for this Ligand-Target Pair | |
Kynurenine 3-monooxygenase
(Rattus norvegicus) | BDBM50061907
((+/-)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric aci...)Show InChI InChI=1S/C10H10N2O5/c11-8(10(14)15)5-9(13)6-2-1-3-7(4-6)12(16)17/h1-4,8H,5,11H2,(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit kynurenine-3-hydroxylase was determined in a competitive inhibition assay. |
J Med Chem 37: 647-55 (1994)
BindingDB Entry DOI: 10.7270/Q2VD703H |
More data for this Ligand-Target Pair | |
Kynurenine 3-monooxygenase
(Rattus norvegicus) | BDBM50061907
((+/-)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric aci...)Show InChI InChI=1S/C10H10N2O5/c11-8(10(14)15)5-9(13)6-2-1-3-7(4-6)12(16)17/h1-4,8H,5,11H2,(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested for inhibitory activity against Kynurenine 3-hydroxylase |
Bioorg Med Chem Lett 5: 1451-1454 (1995)
Article DOI: 10.1016/0960-894X(95)00255-R BindingDB Entry DOI: 10.7270/Q2PR7VZZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030630
((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M Concentration |
J Med Chem 38: 3717-9 (1995)
BindingDB Entry DOI: 10.7270/Q2V123TG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50076393
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030628
((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)Show InChI InChI=1S/C9H9NO5/c10-7(9(14)15)4-1-2-5(8(12)13)6(11)3-4/h1-3,7,11H,10H2,(H,12,13)(H,14,15) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M Concentration |
J Med Chem 38: 3717-9 (1995)
BindingDB Entry DOI: 10.7270/Q2V123TG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50030628
((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)Show InChI InChI=1S/C9H9NO5/c10-7(9(14)15)4-1-2-5(8(12)13)6(11)3-4/h1-3,7,11H,10H2,(H,12,13)(H,14,15) | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
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| PubMed
| n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M Concentration |
J Med Chem 38: 3717-9 (1995)
BindingDB Entry DOI: 10.7270/Q2V123TG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50030627
((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15) | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Antagonistic activity against mGluR2 was determined |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Kynureninase
(Rattus norvegicus) | BDBM50083950
((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)Show SMILES N[C@@H](CC(=O)c1cccc(c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C10H10N2O5/c11-8(10(14)15)5-9(13)6-2-1-3-7(4-6)12(16)17/h1-4,8H,5,11H2,(H,14,15)/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested for inhibitory activity against kynureninase from rat liver |
Bioorg Med Chem Lett 5: 1451-1454 (1995)
Article DOI: 10.1016/0960-894X(95)00255-R BindingDB Entry DOI: 10.7270/Q2PR7VZZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030629
((R,S)-4-Carboxy-3-hydroxyphenylglycine | (S)-4CPG ...)Show InChI InChI=1S/C9H9NO4/c10-7(9(13)14)5-1-3-6(4-2-5)8(11)12/h1-4,7H,10H2,(H,11,12)(H,13,14) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M Concentration |
J Med Chem 38: 3717-9 (1995)
BindingDB Entry DOI: 10.7270/Q2V123TG |
More data for this Ligand-Target Pair | |
Kynureninase
(Rattus norvegicus) | BDBM50061907
((+/-)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric aci...)Show InChI InChI=1S/C10H10N2O5/c11-8(10(14)15)5-9(13)6-2-1-3-7(4-6)12(16)17/h1-4,8H,5,11H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit kynureninase was determined in a competitive inhibition assay. |
J Med Chem 37: 647-55 (1994)
BindingDB Entry DOI: 10.7270/Q2VD703H |
More data for this Ligand-Target Pair | |
Kynureninase
(Rattus norvegicus) | BDBM50284766
((R)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)Show InChI InChI=1S/C10H10N2O5/c11-8(10(14)15)5-9(13)6-2-1-3-7(4-6)12(16)17/h1-4,8H,5,11H2,(H,14,15)/t8-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested for inhibitory activity against kynureninase from rat liver |
Bioorg Med Chem Lett 5: 1451-1454 (1995)
Article DOI: 10.1016/0960-894X(95)00255-R BindingDB Entry DOI: 10.7270/Q2PR7VZZ |
More data for this Ligand-Target Pair | |
Kynureninase
(Rattus norvegicus) | BDBM50040567
(CHEMBL158499 | ortho-nitrobenzoyl)alanine)Show SMILES [NH3+]C(CC(=O)c1ccccc1[N+]([O-])=O)C([O-])=O Show InChI InChI=1S/C10H10N2O5/c11-7(10(14)15)5-9(13)6-3-1-2-4-8(6)12(16)17/h1-4,7H,5,11H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit kynureninase was determined in a competitive inhibition assay. |
J Med Chem 37: 647-55 (1994)
BindingDB Entry DOI: 10.7270/Q2VD703H |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50407819
(CHEMBL2115152)Show SMILES N[C@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
(Homo sapiens (Human)) | BDBM50030627
((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Antagonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slices |
J Med Chem 42: 2716-20 (1999)
Article DOI: 10.1021/jm990128v BindingDB Entry DOI: 10.7270/Q2JD4W00 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50030627
((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15) | PDB
UniProtKB/SwissProt
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 1.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M Concentration |
J Med Chem 38: 3717-9 (1995)
BindingDB Entry DOI: 10.7270/Q2V123TG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407828
(CHEMBL2114106)Show SMILES N[C@@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50407824
(CHEMBL2114115)Show SMILES N[C@@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4 |
J Med Chem 39: 2259-69 (1996)
Article DOI: 10.1021/jm960059+ BindingDB Entry DOI: 10.7270/Q2Z60N5G |
More data for this Ligand-Target Pair | |