Compile Data Set for Download or QSAR

Found 225 hits with Last Name = 'muth' and Initial = 'ea'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM82071 (CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM82071 (CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM82071 (CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM82071 (CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM82071 (CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367721 (CHEMBL1202512) Show SMILES O=C1C2C(C3CCC2C2CCC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C24H33N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3,8-9,16-21H,1-2,4-7,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367437 (CHEMBL1743956) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCCCc3ccnc4ccccc34)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C30H27F2N3/c31-22-8-11-24(12-9-22)35-29-13-10-23(32)19-26(29)27-20-34(18-15-30(27)35)17-4-3-5-21-14-16-33-28-7-2-1-6-25(21)28/h1-2,6-14,16,19H,3-5,15,17-18,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367438 (CHEMBL1743957) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCc3ccc4ccccc4n3)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C28H23F2N3/c29-20-6-10-23(11-7-20)33-27-12-8-21(30)17-24(27)25-18-32(16-14-28(25)33)15-13-22-9-5-19-3-1-2-4-26(19)31-22/h1-12,17H,13-16,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367726 (CHEMBL1202507) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)C2=O)CC1 |c:23,THB:26:27:23.22:19.20,26:25:23.22:19.20,28:20:23.22:27.25| Show InChI InChI=1S/C26H33N3O3/c1-32-22-7-3-2-6-21(22)28-14-12-27(13-15-28)10-4-5-11-29-25(30)23-17-8-9-18(20-16-19(17)20)24(23)26(29)31/h2-3,6-9,17-20,23-24H,4-5,10-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367719 (CHEMBL1202513) Show SMILES O=C1C2C(C3C=CC2C2CCC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |c:5| Show InChI InChI=1S/C24H31N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3,6-9,16-21H,1-2,4-5,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367735 (CHEMBL1204093) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3C=CC43)C2=O)CC1 |c:23,28| Show InChI InChI=1S/C27H33N3O3/c1-33-23-7-3-2-6-22(23)29-16-14-28(15-17-29)12-4-5-13-30-26(31)24-20-10-11-21(25(24)27(30)32)19-9-8-18(19)20/h2-3,6-11,18-21,24-25H,4-5,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound; value may ra...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM82071 (CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM82071 (CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	3.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50367417 (CHEMBL1743943) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCc3ccccn3)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C24H21F2N3/c25-17-4-7-20(8-5-17)29-23-9-6-18(26)15-21(23)22-16-28(14-11-24(22)29)13-10-19-3-1-2-12-27-19/h1-9,12,15H,10-11,13-14,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]spiperone as the radioligand in rat cortical tissue; value may range from 2.4 to 5.3				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity for dopamine receptor D2 of rat nucleus accumbens labeled with [3H]-spiperone				J Med Chem 30: 1100-5 (1987) BindingDB Entry DOI: 10.7270/Q2K35SNV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]-Spiperone as the radioligand in rat limbic system at 1 uM concentration of compound				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367419 (CHEMBL1743958) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCc3cnccn3)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C23H20F2N4/c24-16-1-4-19(5-2-16)29-22-6-3-17(25)13-20(22)21-15-28(12-8-23(21)29)11-7-18-14-26-9-10-27-18/h1-6,9-10,13-14H,7-8,11-12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367733 (CHEMBL1202527) Show SMILES O=C1C2C(C3CCC2CCC3)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |TLB:11:3:8.9.10:5.6,THB:1:2:8.9.10:5.6| Show InChI InChI=1S/C23H33N5O2/c29-21-19-17-5-3-6-18(8-7-17)20(19)22(30)28(21)12-2-1-11-26-13-15-27(16-14-26)23-24-9-4-10-25-23/h4,9-10,17-20H,1-3,5-8,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367736 (CHEMBL1202530) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)C(=O)C23C4CCC(C4)C12C1CCC3C1 |THB:1:27:23.24:26,1:27:29.30:32,19:21:23.24:26,19:21:29.30:32,(-1.53,1.64,;-2.57,.98,;-3.71,1.52,;-4.21,2.97,;-3.19,4.13,;-3.69,5.59,;-2.68,6.75,;-3.17,8.21,;-2.16,9.37,;-2.66,10.83,;-4.17,11.12,;-5.18,9.96,;-4.68,8.51,;-4.67,12.58,;-3.66,13.74,;-4.16,15.2,;-5.68,15.49,;-6.69,14.33,;-6.18,12.87,;-4.37,.07,;-5.4,-.01,;-3.27,-1.59,;-1.93,-1.23,;-.57,-1.59,;.11,-.39,;-1.23,,;-1.64,1,;-2.57,-.39,;-4.3,-.86,;-4.27,-2.5,;-4.96,-3.71,;-5,-2.02,;-5.66,-.5,)| Show InChI InChI=1S/C26H35N5O2/c32-22-25-18-4-5-19(16-18)26(25,21-7-6-20(25)17-21)23(33)31(22)11-2-1-10-29-12-14-30(15-13-29)24-27-8-3-9-28-24/h3,8-9,18-21H,1-2,4-7,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367433 (CHEMBL1743945) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCCCc3ccncc3)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C26H25F2N3/c27-20-4-7-22(8-5-20)31-25-9-6-21(28)17-23(25)24-18-30(16-12-26(24)31)15-2-1-3-19-10-13-29-14-11-19/h4-11,13-14,17H,1-3,12,15-16,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]-Spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may ...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367417 (CHEMBL1743943) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCc3ccccn3)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C24H21F2N3/c25-17-4-7-20(8-5-17)29-23-9-6-18(26)15-21(23)22-16-28(14-11-24(22)29)13-10-19-3-1-2-12-27-19/h1-9,12,15H,10-11,13-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020115 (4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4-az...) Show SMILES O=C1C2C3CCC(C3)C2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001888 ((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...) Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity for dopamine receptor D2 of rat nucleus accumbens labeled with [3H]-spiperone				J Med Chem 30: 1100-5 (1987) BindingDB Entry DOI: 10.7270/Q2K35SNV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]-Spiperone as the radioligand in rat cortical tissue.				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50005127 (1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367731 (CHEMBL1202506) Show SMILES O=C1C2C(C3CCCC2C=C3)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |c:10,TLB:1:2:7.6.5:10.9,THB:11:3:7.6.5:10.9| Show InChI InChI=1S/C23H31N5O2/c29-21-19-17-5-3-6-18(8-7-17)20(19)22(30)28(21)12-2-1-11-26-13-15-27(16-14-26)23-24-9-4-10-25-23/h4,7-10,17-20H,1-3,5-6,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367432 (CHEMBL1743937) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCc3ccncc3)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C24H21F2N3/c25-18-1-4-20(5-2-18)29-23-6-3-19(26)15-21(23)22-16-28(14-10-24(22)29)13-9-17-7-11-27-12-8-17/h1-8,11-12,15H,9-10,13-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367723 (CHEMBL1202494) Show SMILES O=C1C2C(C3CCC2C2CC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |THB:1:2:6.5:10.8,9:10:6.5:2.3,9:8:6.5:2.3| Show InChI InChI=1S/C23H31N5O2/c29-21-19-15-4-5-16(18-14-17(15)18)20(19)22(30)28(21)9-2-1-8-26-10-12-27(13-11-26)23-24-6-3-7-25-23/h3,6-7,15-20H,1-2,4-5,8-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020142 (4-{4-[4-(3-chlorophenyl)hexahydro-1-pyrazinyl]buty...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)C2=O)CC1 |c:22,(21.6,-11.25,;20.27,-12.02,;20.27,-13.58,;18.94,-14.33,;17.62,-13.56,;17.63,-12.02,;18.94,-11.25,;16.28,-11.25,;14.96,-12.02,;13.62,-11.25,;13.64,-9.72,;12.31,-8.95,;10.99,-9.72,;9.65,-8.95,;8.33,-9.72,;6.99,-8.95,;5.57,-9.58,;5.26,-11.06,;4.55,-8.43,;5.33,-7.09,;4.56,-5.77,;3.23,-6.58,;4.32,-7.67,;2.99,-8.46,;2.22,-7.11,;1.45,-5.77,;2.99,-5.77,;6.82,-7.43,;7.95,-6.38,;14.97,-8.95,;16.3,-9.72,)| Show InChI InChI=1S/C25H30ClN3O2/c26-16-4-3-5-17(14-16)28-12-10-27(11-13-28)8-1-2-9-29-24(30)22-18-6-7-19(21-15-20(18)21)23(22)25(29)31/h3-7,14,18-23H,1-2,8-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367725 (CHEMBL1202520) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)C(=O)C23C4CC(C=C4)C12C1CC3C=C1 |c:27,37,TLB:1:27:23:25.26,1:27:29:31.32,19:21:23:25.26,19:21:29:31.32,(-1.53,1.64,;-2.57,.98,;-3.71,1.52,;-4.21,2.97,;-3.19,4.13,;-3.69,5.59,;-2.68,6.75,;-3.17,8.21,;-2.16,9.37,;-2.66,10.83,;-4.17,11.12,;-5.18,9.96,;-4.68,8.51,;-4.67,12.58,;-3.66,13.74,;-4.16,15.2,;-5.68,15.49,;-6.69,14.33,;-6.18,12.87,;-4.37,.07,;-5.4,-.01,;-3.27,-1.59,;-1.93,-1.23,;-1.64,1,;-1.23,,;.11,-.39,;-.57,-1.59,;-2.57,-.39,;-4.3,-.86,;-5.66,-.5,;-5,-2.02,;-4.96,-3.71,;-4.27,-2.5,)| Show InChI InChI=1S/C26H31N5O2/c32-22-25-18-4-5-19(16-18)26(25,21-7-6-20(25)17-21)23(33)31(22)11-2-1-10-29-12-14-30(15-13-29)24-27-8-3-9-28-24/h3-9,18-21H,1-2,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367726 (CHEMBL1202507) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)C2=O)CC1 |c:23,THB:26:27:23.22:19.20,26:25:23.22:19.20,28:20:23.22:27.25| Show InChI InChI=1S/C26H33N3O3/c1-32-22-7-3-2-6-21(22)28-14-12-27(13-15-28)10-4-5-11-29-25(30)23-17-8-9-18(20-16-19(17)20)24(23)26(29)31/h2-3,6-9,17-20,23-24H,4-5,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat brain limbic tissue				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367734 (CHEMBL1202523) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)C3C(C4CCC3CCC4)C2=O)CC1 |TLB:19:21:27.28.29:24.25,THB:30:22:27.28.29:24.25| Show InChI InChI=1S/C26H34F3N3O2/c27-26(28,29)20-7-4-8-21(17-20)31-15-13-30(14-16-31)11-1-2-12-32-24(33)22-18-5-3-6-19(10-9-18)23(22)25(32)34/h4,7-8,17-19,22-23H,1-3,5-6,9-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367729 (CHEMBL1204094) Show SMILES O=C1C2C(C3C=CC2C2C=CC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |c:5,10| Show InChI InChI=1S/C24H29N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3-9,16-21H,1-2,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367425 (CHEMBL1743955) Show SMILES Fc1ccc(cc1)C(CCCN1CCc2[nH]c3ccc(F)cc3c2C1)c1ccc(F)cc1 Show InChI InChI=1S/C27H25F3N2/c28-20-7-3-18(4-8-20)23(19-5-9-21(29)10-6-19)2-1-14-32-15-13-27-25(17-32)24-16-22(30)11-12-26(24)31-27/h3-12,16,23,31H,1-2,13-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020126 (4-{4-[4-(3-chlorophenyl)hexahydro-1-pyrazinyl]buty...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CCC43)C2=O)CC1 |c:22,(26.79,-15.91,;25.45,-16.69,;25.45,-18.23,;24.13,-19,;22.79,-18.23,;22.81,-16.69,;24.14,-15.92,;21.47,-15.91,;20.13,-16.68,;18.81,-15.91,;18.81,-14.37,;17.5,-13.6,;16.15,-14.37,;14.82,-13.6,;13.49,-14.37,;12.16,-13.6,;11.98,-12.07,;13.13,-11.05,;10.49,-11.75,;9.7,-13.1,;8.16,-13.1,;9.48,-12.33,;8.38,-11.24,;9.72,-10.41,;8.16,-10.43,;6.81,-9.66,;6.04,-10.98,;7.39,-11.75,;10.73,-14.22,;10.43,-15.73,;20.15,-13.6,;21.47,-14.37,)| Show InChI InChI=1S/C26H32ClN3O2/c27-17-4-3-5-18(16-17)29-14-12-28(13-15-29)10-1-2-11-30-25(31)23-21-8-9-22(24(23)26(30)32)20-7-6-19(20)21/h3-5,8-9,16,19-24H,1-2,6-7,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367732 (CHEMBL1202493) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)C3C(C4CCC3C3CC43)C2=O)CC1 |THB:28:29:25.24:21.22,28:27:25.24:21.22,30:22:25.24:29.27| Show InChI InChI=1S/C26H32F3N3O2/c27-26(28,29)16-4-3-5-17(14-16)31-12-10-30(11-13-31)8-1-2-9-32-24(33)22-18-6-7-19(21-15-20(18)21)23(22)25(32)34/h3-5,14,18-23H,1-2,6-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories, Inc. Curated by PDSP Ki Database									Biochem Pharmacol 35: 4493-7 (1986) Article DOI: 10.1016/0006-2952(86)90769-0 BindingDB Entry DOI: 10.7270/Q22J69CP
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50367419 (CHEMBL1743958) Show SMILES Fc1ccc(cc1)-n1c2CCN(CCc3cnccn3)Cc2c2cc(F)ccc12 Show InChI InChI=1S/C23H20F2N4/c24-16-1-4-19(5-2-16)29-22-6-3-17(25)13-20(22)21-15-28(12-8-23(21)29)11-7-18-14-26-9-10-27-18/h1-6,9-10,13-14H,7-8,11-12,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]spiperone as the radioligand in rat cortical tissue; value may range from 6 to 75				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367728 (CHEMBL1202515) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3C=CC43)C2=O)CC1 |c:25,30| Show InChI InChI=1S/C27H30F3N3O2/c28-27(29,30)17-4-3-5-18(16-17)32-14-12-31(13-15-32)10-1-2-11-33-25(34)23-21-8-9-22(24(23)26(33)35)20-7-6-19(20)21/h3-9,16,19-24H,1-2,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367422 (CHEMBL1743935) Show SMILES Fc1ccc2[nH]c3CCN(CCc4ccccn4)Cc3c2c1 Show InChI InChI=1S/C18H18FN3/c19-13-4-5-17-15(11-13)16-12-22(10-7-18(16)21-17)9-6-14-3-1-2-8-20-14/h1-5,8,11,21H,6-7,9-10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50367730 (CHEMBL1202508) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)C2=O)CC1 |c:25,THB:28:29:25.24:21.22,28:27:25.24:21.22,30:22:25.24:29.27| Show InChI InChI=1S/C26H30F3N3O2/c27-26(28,29)16-4-3-5-17(14-16)31-12-10-30(11-13-31)8-1-2-9-32-24(33)22-18-6-7-19(21-15-20(18)21)23(22)25(32)34/h3-7,14,18-23H,1-2,8-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020145 (4-{4-[4-(3-chloro-2-pyrazinyl)hexahydro-1-pyraziny...) Show SMILES Clc1nccnc1N1CCN(CCCCN2C(=O)C3C(C4CCC3C3CC43)C2=O)CC1 Show InChI InChI=1S/C23H30ClN5O2/c24-20-21(26-6-5-25-20)28-11-9-27(10-12-28)7-1-2-8-29-22(30)18-14-3-4-15(17-13-16(14)17)19(18)23(29)31/h5-6,14-19H,1-4,7-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound; value may ra...				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50367435 (CHEMBL1743938) Show SMILES Clc1ccc2[nH]c3CCN(CCCc4cccnc4)Cc3c2c1 Show InChI InChI=1S/C19H20ClN3/c20-15-5-6-18-16(11-15)17-13-23(10-7-19(17)22-18)9-2-4-14-3-1-8-21-12-14/h1,3,5-6,8,11-12,22H,2,4,7,9-10,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]-Spiperone as the radioligand in rat cortical tissue; value may range from 12 to 66				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity for dopamine receptor D2 of rat nucleus accumbens labeled with [3H]-spiperone				J Med Chem 30: 1100-5 (1987) BindingDB Entry DOI: 10.7270/Q2K35SNV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description In vitro Dopamine receptor D2 affinity by using [3H]-Spiperone as the radioligand in rat limbic system at 1 uM concentration of compound				J Med Chem 30: 1818-23 (1987) BindingDB Entry DOI: 10.7270/Q2NS0VG2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020121 (4-[4-(3'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazin...) Show SMILES Clc1nccnc1N1CCN(CCCCN2C(=O)C3C4CC(C=C4)C3C2=O)CC1 |c:23| Show InChI InChI=1S/C21H26ClN5O2/c22-18-19(24-6-5-23-18)26-11-9-25(10-12-26)7-1-2-8-27-20(28)16-14-3-4-15(13-14)17(16)21(27)29/h3-6,14-17H,1-2,7-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.				J Med Chem 31: 1382-92 (1988) BindingDB Entry DOI: 10.7270/Q2PC32Z4
					More data for this Ligand-Target Pair

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