BindingDB PrimarySearch

Found 148 hits with Last Name = 'narayanan' and Initial = 'a'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103072 (1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole \| CHEM...) Show SMILES C(c1ccccc1)n1c(nc2ccccc12)N1CCNCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103070 (1-(4-Methoxy-benzyl)-2-piperazin-1-yl-1H-benzoimid...) Show SMILES COc1ccc(Cn2c(nc3ccccc23)N2CCNCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103076 (1-Naphthalen-2-ylmethyl-2-piperazin-1-yl-1H-benzoi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103075 (1-(4-Methyl-benzyl)-2-piperazin-1-yl-1H-benzoimida...) Show SMILES Cc1ccc(Cn2c(nc3ccccc23)N2CCNCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103069 (1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimida...) Show SMILES Fc1ccc(Cn2c(nc3ccccc23)N2CCNCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103073 (1-Phenethyl-2-piperazin-1-yl-1H-benzoimidazole \| C...) Show SMILES C(Cn1c(nc2ccccc12)N1CCNCC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103071 (1-(3-Phenyl-propyl)-2-piperazin-1-yl-1H-benzoimida...) Show SMILES C(Cc1ccccc1)Cn1c(nc2ccccc12)N1CCNCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50103077 (2-Piperazin-1-yl-1H-benzoimidazole \| CHEMBL292066) Show SMILES C1CN(CCN1)c1nc2ccccc2[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Louisiana at Monroe Curated by ChEMBL					Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor				Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG
The University of Louisiana at Monroe Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565931 (CHEMBL4787096) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565919 (CHEMBL4794362) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565920 (CHEMBL4784517) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565925 (CHEMBL4778780) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565921 (CHEMBL4781765) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565918 (CHEMBL4778108) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565917 (CHEMBL4783261) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565922 (CHEMBL4797664) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565929 (Pf-07059013) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	>3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565928 (CHEMBL4785484) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565927 (CHEMBL4779453) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565926 (CHEMBL4778770) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565923 (CHEMBL4762748) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565916 (CHEMBL4777878) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565924 (CHEMBL4795396) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565930 (CHEMBL4796436) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human ERG by dofetilide fluorescence polarization binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01518 BindingDB Entry DOI: 10.7270/Q2QC079V
TBA					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50232534 (5-((2-fluorophenoxy)methyl)quinazoline-2,4-diamine...) Show SMILES Nc1nc(N)c2c(COc3ccccc3F)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50232526 (5-((2,4-difluorophenoxy)methyl)quinazoline-2,4-dia...) Show SMILES Nc1nc(N)c2c(COc3ccc(F)cc3F)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50232538 (5-((1-(2-fluorobenzyl)piperidin-4-yl)methoxy)quina...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237216 (CHEMBL4080254) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237201 (CHEMBL4082618) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50232589 (5-((3-chlorophenoxy)methyl)quinazoline-2,4-diamine...) Show SMILES Nc1nc(N)c2c(COc3cccc(Cl)c3)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237200 (CHEMBL4072132) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0690	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM36530 (D157493) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity towards 5-HT3 receptor in rat was evaluated				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237203 (CHEMBL250072) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237199 (CHEMBL4077061) Show SMILES Nc1nc(N)c2c(COc3cc(F)cc(c3)C#N)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237205 (CHEMBL398675) Show SMILES Nc1nc(N)c2c(OCc3cc(F)cc(F)c3)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237209 (CHEMBL4062544) Show SMILES Nc1nc(N)c2c(COc3cccc(F)c3)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237211 (CHEMBL4061457) Show SMILES Cc1ncccc1OCc1cccc2nc(N)nc(N)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237210 (CHEMBL399673) Show SMILES Nc1nc(N)c2c(COc3ccccc3Cl)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM36534 (D156095) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237217 (CHEMBL342595) Show SMILES Nc1nc(N)c2c(OCc3ccccc3)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluated				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237202 (CHEMBL4103454) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237198 (CHEMBL4068466) Show SMILES Nc1nc(N)c2c(OCC3CCOCC3)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237218 (CHEMBL4072481) Show SMILES Nc1nc(N)c2c(COC3CCOCC3)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50232566 (5-(3-chlorobenzyloxy)quinazoline-2,4-diamine \| CHE...) Show SMILES Nc1nc(N)c2c(OCc3cccc(Cl)c3)cccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237204 (CHEMBL343543) Show SMILES COc1cccc2nc(N)nc(N)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237206 (CHEMBL4075292) Show SMILES CC1(COc2cccc3nc(N)nc(N)c23)COC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237212 (CHEMBL4100442) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237214 (CHEMBL4084161) Show SMILES COC[C@H](C)Oc1cccc2nc(N)nc(N)c12 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity towards 5-HT3 receptor in rat was evaluated				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237208 (CHEMBL4090641) Show SMILES COC[C@@H](C)Oc1cccc2nc(N)nc(N)c12 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50398093 (CHEMBL2182046 \| US9321738, 6) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 expressed in chem-1 cells assessed as inhibition of LPA-induced intracellular calcium mobilization incu...				J Med Chem 55: 7920-39 (2012) Article DOI: 10.1021/jm301022v BindingDB Entry DOI: 10.7270/Q26974Q9
Hoffmann-La Roche Curated by ChEMBL					More data for this Ligand-Target Pair

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