BindingDB PrimarySearch

Found 24 hits with Last Name = 'negi' and Initial = 'as'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM19461 (α-CA inhibitor, 5 \| 5,7-dihydroxy-2-(4-hydrox...) Show SMILES Oc1ccc(cc1)C1CC(=O)c2c(O)cc(O)cc2O1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.00110	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92556 (Neoflavonoid, 8) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.00182	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92555 (Neoflavonoid, 7) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.00216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92557 (Neoflavonoid, 9) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.00256	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92559 (Neoflavonoid, 11) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.00425	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92560 (Neoflavonoid, 19) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.00597	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92558 (Neoflavonoid, 10) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.00838	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92561 (Neoflavonoid, 20) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.0118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Institute of Medicinal and Aromatic Plants					Assay Description Inhibition assay using aromatase enzyme.				Chem Biol Drug Des 80: 616-624 (2012) Article DOI: 10.1111/j.1747-0285.2012.01439.x BindingDB Entry DOI: 10.7270/Q24X56CG
Central Institute of Medicinal and Aromatic Plants					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM912 ((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189981 (2-[1-(3,4,5-trimethoxybenzoyl)naphthalen-2-yloxy]e...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189983 (CHEMBL214974 \| N-butyl-4-(1-(3,4,5-trimethoxybenzo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189976 (CHEMBL212492 \| N-(4-methoxyphenyl)-4-(1-(3,4,5-tri...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189980 (CHEMBL213373 \| N-octyl-2-(1-(3,4,5-trimethoxybenzo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189985 (4-[1-(3,4,5-trimethoxybenzoyl)naphthalen-2-yloxy]-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM21690 (1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 as substrate after 30 mins by agarose gel electrophore...				Bioorg Med Chem 26: 4551-4559 (2018) Article DOI: 10.1016/j.bmc.2018.07.049 BindingDB Entry DOI: 10.7270/Q2XD14C3
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50463548 (CHEMBL4239753) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 as substrate after 30 mins by agarose gel electrophore...				Bioorg Med Chem 26: 4551-4559 (2018) Article DOI: 10.1016/j.bmc.2018.07.049 BindingDB Entry DOI: 10.7270/Q2XD14C3
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189984 (CHEMBL378015 \| N-phenyl-2-(1-(3,4,5-trimethoxybenz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50463549 (CHEMBL4237298) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 as substrate after 30 mins by agarose gel electrophore...				Bioorg Med Chem 26: 4551-4559 (2018) Article DOI: 10.1016/j.bmc.2018.07.049 BindingDB Entry DOI: 10.7270/Q2XD14C3
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50463550 (CHEMBL4251156) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 as substrate after 30 mins by agarose gel electrophore...				Bioorg Med Chem 26: 4551-4559 (2018) Article DOI: 10.1016/j.bmc.2018.07.049 BindingDB Entry DOI: 10.7270/Q2XD14C3
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50463551 (CHEMBL4243541) Show SMILES COc1ccc2[nH]c(nc2c1)-c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 as substrate after 30 mins by agarose gel electrophore...				Bioorg Med Chem 26: 4551-4559 (2018) Article DOI: 10.1016/j.bmc.2018.07.049 BindingDB Entry DOI: 10.7270/Q2XD14C3
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189979 (CHEMBL378329 \| N-phenyl-4-(1-(3,4,5-trimethoxybenz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189978 (CHEMBL377142 \| N-(4-methoxyphenyl)-2-(1-(3,4,5-tri...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189977 (4-(1-(3,4,5-trimethoxybenzoyl)naphthalen-2-yloxy)b...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50189982 (2-[1-(3,4,5-trimethoxybenzoyl)naphthalene-2-yloxy]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of human cathepsin D				Bioorg Med Chem Lett 16: 4603-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.010 BindingDB Entry DOI: 10.7270/Q2FB53QN
					More data for this Ligand-Target Pair