Found 463 hits with Last Name = 'nourrisson' and Initial = 'mr' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM100152
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM100152
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50568546
(CHEMBL4853288) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50443934
(CHEMBL3091797)Show InChI InChI=1S/C15H8Cl2N4O/c16-8-1-2-9(10(17)4-8)7-3-11-12(19-5-7)13-14(22-11)15(18)21-6-20-13/h1-6H,(H2,18,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070528
(CHEMBL3408804)Show InChI InChI=1S/C16H11FN4OS/c1-22-9-2-3-10(12(17)5-9)8-4-11-13-14(15(18)21-7-20-13)23-16(11)19-6-8/h2-7H,1H3,(H2,18,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM100152
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of DYRK1A (unknown origin) |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070560
(CHEMBL3408799)Show InChI InChI=1S/C15H8Cl2N4S/c16-8-1-2-9(11(17)4-8)7-3-10-12-13(14(18)21-6-20-12)22-15(10)19-5-7/h1-6H,(H2,18,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070504
(CHEMBL3408810)Show InChI InChI=1S/C15H8Cl2N4S/c16-7-1-2-8(10(17)5-7)11-4-3-9-12-13(22-15(9)21-11)14(18)20-6-19-12/h1-6H,(H2,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070547
(CHEMBL3408802)Show InChI InChI=1S/C15H8ClFN4S/c16-8-1-2-9(11(17)4-8)7-3-10-12-13(14(18)21-6-20-12)22-15(10)19-5-7/h1-6H,(H2,18,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070553
(CHEMBL3408801)Show InChI InChI=1S/C15H8F2N4S/c16-8-1-2-9(11(17)4-8)7-3-10-12-13(14(18)21-6-20-12)22-15(10)19-5-7/h1-6H,(H2,18,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50568544
(CHEMBL4870529)Show SMILES CN(C)c1nccn2c(c(nc12)-c1ccc(F)cc1)-c1ccnc(N)n1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrate |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50568545
(CHEMBL4877608)Show SMILES CSc1nccc(n1)-c1c(nc2c(N)nccn12)-c1ccc(F)cc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50568545
(CHEMBL4877608)Show SMILES CSc1nccc(n1)-c1c(nc2c(N)nccn12)-c1ccc(F)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrate |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070506
(CHEMBL3408808)Show InChI InChI=1S/C13H8N4S2/c14-12-11-10(16-6-17-12)8-4-7(5-15-13(8)19-11)9-2-1-3-18-9/h1-6H,(H2,14,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM27437
(12-phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,...)Show InChI InChI=1S/C15H10N4S/c16-14-13-12(18-8-19-14)11-6-10(7-17-15(11)20-13)9-4-2-1-3-5-9/h1-8H,(H2,16,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070529
(CHEMBL3408803)Show InChI InChI=1S/C15H8ClFN4S/c16-11-4-8(17)1-2-9(11)7-3-10-12-13(14(18)21-6-20-12)22-15(10)19-5-7/h1-6H,(H2,18,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50568546
(CHEMBL4853288) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrate |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50568544
(CHEMBL4870529)Show SMILES CN(C)c1nccn2c(c(nc12)-c1ccc(F)cc1)-c1ccnc(N)n1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070578
(CHEMBL3408795)Show InChI InChI=1S/C16H12N4OS/c1-21-11-4-2-9(3-5-11)10-6-12-13-14(15(17)20-8-19-13)22-16(12)18-7-10/h2-8H,1H3,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50443933
(CHEMBL3091798)Show InChI InChI=1S/C16H10N4O3/c17-16-15-14(19-6-20-16)13-12(23-15)4-9(5-18-13)8-1-2-10-11(3-8)22-7-21-10/h1-6H,7H2,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50070529
(CHEMBL3408803)Show InChI InChI=1S/C15H8ClFN4S/c16-11-4-8(17)1-2-9(11)7-3-10-12-13(14(18)21-6-20-12)22-15(10)19-5-7/h1-6H,(H2,18,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti... |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50424711
(CHEMBL2314163)Show InChI InChI=1S/C11H9N3O2/c1-15-6-2-3-7-8(4-6)16-10-9(7)13-5-14-11(10)12/h2-5H,1H3,(H2,12,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424676
(CHEMBL2313912)Show InChI InChI=1S/C19H15N3O3S/c1-23-12-3-4-13-16(9-12)26-18-17(13)20-10-21-19(18)22-11-2-5-14-15(8-11)25-7-6-24-14/h2-5,8-10H,6-7H2,1H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50568546
(CHEMBL4853288) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant CDK9/CyclinT expressed in baculovirus infected Sf9 cells using YSPTSPSYSPTSPSYSPTSPSKKK as substrate in presence of [... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070508
(CHEMBL3408806)Show SMILES Nc1ncnc2c1sc1ncc(cc21)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H9N5O2S/c16-14-13-12(18-7-19-14)11-5-9(6-17-15(11)23-13)8-1-3-10(4-2-8)20(21)22/h1-7H,(H2,16,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070507
(CHEMBL3408807)Show InChI InChI=1S/C16H10N4O2S/c17-15-14-13(19-6-20-15)10-3-9(5-18-16(10)23-14)8-1-2-11-12(4-8)22-7-21-11/h1-6H,7H2,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50070560
(CHEMBL3408799)Show InChI InChI=1S/C15H8Cl2N4S/c16-8-1-2-9(11(17)4-8)7-3-10-12-13(14(18)21-6-20-12)22-15(10)19-5-7/h1-6H,(H2,18,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti... |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50568541
(CHEMBL4860872)Show SMILES CN(C)c1nccn2c(c(nc12)-c1ccccc1)-c1ccnc(N)n1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50443934
(CHEMBL3091797)Show InChI InChI=1S/C15H8Cl2N4O/c16-8-1-2-9(10(17)4-8)7-3-11-12(19-5-7)13-14(22-11)15(18)21-6-20-13/h1-6H,(H2,18,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti... |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50443938
(CHEMBL3091818)Show InChI InChI=1S/C16H12N4O/c1-9-2-4-10(5-3-9)11-6-12-13(18-7-11)14-15(21-12)16(17)20-8-19-14/h2-8H,1H3,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424671
(CHEMBL2313917)Show InChI InChI=1S/C17H12ClN3OS/c1-22-10-6-7-11-14(8-10)23-16-15(11)19-9-20-17(16)21-13-5-3-2-4-12(13)18/h2-9H,1H3,(H,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424660
(CHEMBL2313884)Show InChI InChI=1S/C19H18N4OS/c1-23(2)13-6-4-12(5-7-13)22-19-18-17(20-11-21-19)15-9-8-14(24-3)10-16(15)25-18/h4-11H,1-3H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50424676
(CHEMBL2313912)Show InChI InChI=1S/C19H15N3O3S/c1-23-12-3-4-13-16(9-12)26-18-17(13)20-10-21-19(18)22-11-2-5-14-15(8-11)25-7-6-24-14/h2-5,8-10H,6-7H2,1H3,(H,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM27439
(8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca...)Show InChI InChI=1S/C9H6N4S/c10-8-7-6(12-4-13-8)5-2-1-3-11-9(5)14-7/h1-4H,(H2,10,12,13) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin... |
Eur J Med Chem 58: 171-83 (2012)
Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50443939
(CHEMBL3091817)Show InChI InChI=1S/C15H10N4O/c16-15-14-13(18-8-19-15)12-11(20-14)6-10(7-17-12)9-4-2-1-3-5-9/h1-8H,(H2,16,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070562
(CHEMBL3408797)Show InChI InChI=1S/C15H9ClN4S/c16-10-3-1-2-8(4-10)9-5-11-12-13(14(17)20-7-19-12)21-15(11)18-6-9/h1-7H,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424663
(CHEMBL2313925)Show InChI InChI=1S/C18H14FN3O2S/c1-23-10-4-6-14(13(19)7-10)22-18-17-16(20-9-21-18)12-5-3-11(24-2)8-15(12)25-17/h3-9H,1-2H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424664
(CHEMBL2313924)Show InChI InChI=1S/C17H11BrFN3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50424660
(CHEMBL2313884)Show InChI InChI=1S/C19H18N4OS/c1-23(2)13-6-4-12(5-7-13)22-19-18-17(20-11-21-19)15-9-8-14(24-3)10-16(15)25-18/h4-11H,1-3H3,(H,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50568546
(CHEMBL4853288) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human CDK2/ cyclinA using histone H1 as substrate in presence of [gamma-33P]ATP by radiometric assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 3
(Homo sapiens (Human)) | BDBM100152
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of DYRK3 (unknown origin) |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424707
(CHEMBL2314167)Show InChI InChI=1S/C18H15N3O3/c1-22-12-5-3-11(4-6-12)21-18-17-16(19-10-20-18)14-8-7-13(23-2)9-15(14)24-17/h3-10H,1-2H3,(H,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50392636
(CHEMBL2153529)Show InChI InChI=1S/C15H8BrFN4S/c16-8-3-4-11(10(17)6-8)21-14-13-12(19-7-20-14)9-2-1-5-18-15(9)22-13/h1-7H,(H,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc... |
Eur J Med Chem 58: 171-83 (2012)
Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50568540
(CHEMBL4872681)Show SMILES CSc1nccc(n1)-c1c(nc2c(nccn12)N(C)C)-c1ccccc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM100152
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3 | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of DYRK2 (unknown origin) |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070527
(CHEMBL3408805)Show InChI InChI=1S/C15H9BrN4S/c16-10-3-1-8(2-4-10)9-5-11-12-13(14(17)20-7-19-12)21-15(11)18-6-9/h1-7H,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50568538
(CHEMBL3634367)Show SMILES CN(C)c1nccn2c(c(nc12)-c1ccc(F)cc1)-c1ccncc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrate |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112956 BindingDB Entry DOI: 10.7270/Q2125XD2 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424680
(CHEMBL2313908)Show InChI InChI=1S/C19H17N3O3S/c1-23-12-5-6-13-16(9-12)26-18-17(13)20-10-21-19(18)22-11-4-7-14(24-2)15(8-11)25-3/h4-10H,1-3H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424665
(CHEMBL2313923)Show InChI InChI=1S/C17H11F2N3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070505
(CHEMBL3408809)Show InChI InChI=1S/C13H8N6S/c14-12-11-10(18-6-19-12)9-1-7(4-17-13(9)20-11)8-2-15-5-16-3-8/h1-6H,(H2,14,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |