Compile Data Set for Download or QSAR

Found 98 hits with Last Name = 'ogura' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042053 (CHEMBL3360172) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)C1(CC1)C#N Show InChI InChI=1S/C23H23FN6O2S/c1-2-30-20(31)19-18(28-22(30)27-17-5-8-26-10-16(17)24)15(12-33-19)14-4-3-9-29(11-14)21(32)23(13-25)6-7-23/h5,8,10,12,14H,2-4,6-7,9,11H2,1H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042036 (CHEMBL3360170) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)OC Show InChI InChI=1S/C20H22FN5O3S/c1-3-26-18(27)17-16(24-19(26)23-15-6-7-22-9-14(15)21)13(11-30-17)12-5-4-8-25(10-12)20(28)29-2/h6-7,9,11-12H,3-5,8,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042037 (CHEMBL3360169) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCN(CC1)C(=O)OC Show InChI InChI=1S/C20H22FN5O3S/c1-3-26-18(27)17-16(24-19(26)23-15-4-7-22-10-14(15)21)13(11-30-17)12-5-8-25(9-6-12)20(28)29-2/h4,7,10-12H,3,5-6,8-9H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042035 (CHEMBL3360171) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)C(C)(C)CO Show InChI InChI=1S/C23H28FN5O3S/c1-4-29-20(31)19-18(27-22(29)26-17-7-8-25-10-16(17)24)15(12-33-19)14-6-5-9-28(11-14)21(32)23(2,3)13-30/h7-8,10,12,14,30H,4-6,9,11,13H2,1-3H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50032540 (CHEMBL3354179) Show SMILES CCn1c(NC2CCCC2)nc2c(csc2c1=O)-c1cccnc1 Show InChI InChI=1S/C18H20N4OS/c1-2-22-17(23)16-15(21-18(22)20-13-7-3-4-8-13)14(11-24-16)12-6-5-9-19-10-12/h5-6,9-11,13H,2-4,7-8H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042039 (CHEMBL3360167) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C(C)(C)O Show InChI InChI=1S/C16H17FN4O2S/c1-4-21-14(22)13-12(9(8-24-13)16(2,3)23)20-15(21)19-11-5-6-18-7-10(11)17/h5-8,23H,4H2,1-3H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042038 (CHEMBL3360168) Show SMILES CCn1c(Nc2ccncc2F)nc2c(CCCO)csc2c1=O Show InChI InChI=1S/C16H17FN4O2S/c1-2-21-15(23)14-13(10(9-24-14)4-3-7-22)20-16(21)19-12-5-6-18-8-11(12)17/h5-6,8-9,22H,2-4,7H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042040 (CHEMBL3360166) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C(C)O Show InChI InChI=1S/C15H15FN4O2S/c1-3-20-14(22)13-12(9(7-23-13)8(2)21)19-15(20)18-11-4-5-17-6-10(11)16/h4-8,21H,3H2,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50042053 (CHEMBL3360172) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)C1(CC1)C#N Show InChI InChI=1S/C23H23FN6O2S/c1-2-30-20(31)19-18(28-22(30)27-17-5-8-26-10-16(17)24)15(12-33-19)14-4-3-9-29(11-14)21(32)23(13-25)6-7-23/h5,8,10,12,14H,2-4,6-7,9,11H2,1H3,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE3A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042053 (CHEMBL3360172) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)C1(CC1)C#N Show InChI InChI=1S/C23H23FN6O2S/c1-2-30-20(31)19-18(28-22(30)27-17-5-8-26-10-16(17)24)15(12-33-19)14-4-3-9-29(11-14)21(32)23(13-25)6-7-23/h5,8,10,12,14H,2-4,6-7,9,11H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042041 (CHEMBL3360165) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C#N Show InChI InChI=1S/C14H10FN5OS/c1-2-20-13(21)12-11(8(5-16)7-22-12)19-14(20)18-10-3-4-17-6-9(10)15/h3-4,6-7H,2H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50042036 (CHEMBL3360170) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)OC Show InChI InChI=1S/C20H22FN5O3S/c1-3-26-18(27)17-16(24-19(26)23-15-6-7-22-9-14(15)21)13(11-30-17)12-5-4-8-25(10-12)20(28)29-2/h6-7,9,11-12H,3-5,8,10H2,1-2H3,(H,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE3A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50042035 (CHEMBL3360171) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)C(C)(C)CO Show InChI InChI=1S/C23H28FN5O3S/c1-4-29-20(31)19-18(27-22(29)26-17-7-8-25-10-16(17)24)15(12-33-19)14-6-5-9-28(11-14)21(32)23(2,3)13-30/h7-8,10,12,14,30H,4-6,9,11,13H2,1-3H3,(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE3A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042045 (CHEMBL3360161) Show SMILES CCn1c(Nc2ccccc2Cl)nc2ccsc2c1=O Show InChI InChI=1S/C14H12ClN3OS/c1-2-18-13(19)12-11(7-8-20-12)17-14(18)16-10-6-4-3-5-9(10)15/h3-8H,2H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042039 (CHEMBL3360167) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C(C)(C)O Show InChI InChI=1S/C16H17FN4O2S/c1-4-21-14(22)13-12(9(8-24-13)16(2,3)23)20-15(21)19-11-5-6-18-7-10(11)17/h5-8,23H,4H2,1-3H3,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216518 (3-(2-(4-(pyridin-3-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccc(cc3)-c3cccnc3)C(=O)c2c1 Show InChI InChI=1S/C23H19N3O3/c27-22(25-29)10-6-16-3-9-20-15-26(23(28)21(20)12-16)14-17-4-7-18(8-5-17)19-2-1-11-24-13-19/h1-13,29H,14-15H2,(H,25,27)/b10-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042042 (CHEMBL3360164) Show SMILES CCn1c(Nc2ccncc2F)nc2ccsc2c1=O Show InChI InChI=1S/C13H11FN4OS/c1-2-18-12(19)11-10(4-6-20-11)17-13(18)16-9-3-5-15-7-8(9)14/h3-7H,2H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042046 (CHEMBL3360160) Show SMILES CCn1c(Nc2ccccc2F)nc2ccsc2c1=O Show InChI InChI=1S/C14H12FN3OS/c1-2-18-13(19)12-11(7-8-20-12)17-14(18)16-10-6-4-3-5-9(10)15/h3-8H,2H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042051 (CHEMBL3360155) Show SMILES CCn1c(Nc2ccccc2C)nc2ccsc2c1=O Show InChI InChI=1S/C15H15N3OS/c1-3-18-14(19)13-12(8-9-20-13)17-15(18)16-11-7-5-4-6-10(11)2/h4-9H,3H2,1-2H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216518 (3-(2-(4-(pyridin-3-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccc(cc3)-c3cccnc3)C(=O)c2c1 Show InChI InChI=1S/C23H19N3O3/c27-22(25-29)10-6-16-3-9-20-15-26(23(28)21(20)12-16)14-17-4-7-18(8-5-17)19-2-1-11-24-13-19/h1-13,29H,14-15H2,(H,25,27)/b10-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216517 (3-(2-biphenyl-4-ylmethyl-3-oxo-2,3-dihydro-1H-isoi...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccc(cc3)-c3ccccc3)C(=O)c2c1 Show InChI InChI=1S/C24H20N2O3/c27-23(25-29)13-9-17-6-12-21-16-26(24(28)22(21)14-17)15-18-7-10-20(11-8-18)19-4-2-1-3-5-19/h1-14,29H,15-16H2,(H,25,27)/b13-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50032569 (CHEMBL3354160) Show SMILES CCn1c(NC2CCCC2)nc2ccsc2c1=O Show InChI InChI=1S/C13H17N3OS/c1-2-16-12(17)11-10(7-8-18-11)15-13(16)14-9-5-3-4-6-9/h7-9H,2-6H2,1H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50032609 (CHEMBL3354155) Show SMILES CC(C)N1CCN(CC1)c1ccc(cc1)-c1cc2nc(NCC=C)n(C)c(=O)c2s1 Show InChI InChI=1S/C23H29N5OS/c1-5-10-24-23-25-19-15-20(30-21(19)22(29)26(23)4)17-6-8-18(9-7-17)28-13-11-27(12-14-28)16(2)3/h5-9,15-16H,1,10-14H2,2-4H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216519 (3-(2-(4-tert-butylbenzyl)-3-oxoisoindolin-5-yl)-N-...) Show SMILES CC(C)(C)c1ccc(CN2Cc3ccc(\C=C\C(=O)NO)cc3C2=O)cc1 Show InChI InChI=1S/C22H24N2O3/c1-22(2,3)18-9-5-16(6-10-18)13-24-14-17-8-4-15(7-11-20(25)23-27)12-19(17)21(24)26/h4-12,27H,13-14H2,1-3H3,(H,23,25)/b11-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042035 (CHEMBL3360171) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)C(C)(C)CO Show InChI InChI=1S/C23H28FN5O3S/c1-4-29-20(31)19-18(27-22(29)26-17-7-8-25-10-16(17)24)15(12-33-19)14-6-5-9-28(11-14)21(32)23(2,3)13-30/h7-8,10,12,14,30H,4-6,9,11,13H2,1-3H3,(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042038 (CHEMBL3360168) Show SMILES CCn1c(Nc2ccncc2F)nc2c(CCCO)csc2c1=O Show InChI InChI=1S/C16H17FN4O2S/c1-2-21-15(23)14-13(10(9-24-14)4-3-7-22)20-16(21)19-12-5-6-18-8-11(12)17/h5-6,8-9,22H,2-4,7H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216515 (3-(2-benzyl-3-oxoisoindolin-5-yl)-N-hydroxyacrylam...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccccc3)C(=O)c2c1 Show InChI InChI=1S/C18H16N2O3/c21-17(19-23)9-7-13-6-8-15-12-20(18(22)16(15)10-13)11-14-4-2-1-3-5-14/h1-10,23H,11-12H2,(H,19,21)/b9-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216517 (3-(2-biphenyl-4-ylmethyl-3-oxo-2,3-dihydro-1H-isoi...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccc(cc3)-c3ccccc3)C(=O)c2c1 Show InChI InChI=1S/C24H20N2O3/c27-23(25-29)13-9-17-6-12-21-16-26(24(28)22(21)14-17)15-18-7-10-20(11-8-18)19-4-2-1-3-5-19/h1-14,29H,15-16H2,(H,25,27)/b13-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216515 (3-(2-benzyl-3-oxoisoindolin-5-yl)-N-hydroxyacrylam...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccccc3)C(=O)c2c1 Show InChI InChI=1S/C18H16N2O3/c21-17(19-23)9-7-13-6-8-15-12-20(18(22)16(15)10-13)11-14-4-2-1-3-5-14/h1-10,23H,11-12H2,(H,19,21)/b9-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216519 (3-(2-(4-tert-butylbenzyl)-3-oxoisoindolin-5-yl)-N-...) Show SMILES CC(C)(C)c1ccc(CN2Cc3ccc(\C=C\C(=O)NO)cc3C2=O)cc1 Show InChI InChI=1S/C22H24N2O3/c1-22(2,3)18-9-5-16(6-10-18)13-24-14-17-8-4-15(7-11-20(25)23-27)12-19(17)21(24)26/h4-12,27H,13-14H2,1-3H3,(H,23,25)/b11-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216515 (3-(2-benzyl-3-oxoisoindolin-5-yl)-N-hydroxyacrylam...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccccc3)C(=O)c2c1 Show InChI InChI=1S/C18H16N2O3/c21-17(19-23)9-7-13-6-8-15-12-20(18(22)16(15)10-13)11-14-4-2-1-3-5-14/h1-10,23H,11-12H2,(H,19,21)/b9-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042036 (CHEMBL3360170) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)OC Show InChI InChI=1S/C20H22FN5O3S/c1-3-26-18(27)17-16(24-19(26)23-15-6-7-22-9-14(15)21)13(11-30-17)12-5-4-8-25(10-12)20(28)29-2/h6-7,9,11-12H,3-5,8,10H2,1-2H3,(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216518 (3-(2-(4-(pyridin-3-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccc(cc3)-c3cccnc3)C(=O)c2c1 Show InChI InChI=1S/C23H19N3O3/c27-22(25-29)10-6-16-3-9-20-15-26(23(28)21(20)12-16)14-17-4-7-18(8-5-17)19-2-1-11-24-13-19/h1-13,29H,14-15H2,(H,25,27)/b10-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042052 (CHEMBL3360154) Show SMILES CCn1c(Nc2ccccc2)nc2ccsc2c1=O Show InChI InChI=1S/C14H13N3OS/c1-2-17-13(18)12-11(8-9-19-12)16-14(17)15-10-6-4-3-5-7-10/h3-9H,2H2,1H3,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042037 (CHEMBL3360169) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCN(CC1)C(=O)OC Show InChI InChI=1S/C20H22FN5O3S/c1-3-26-18(27)17-16(24-19(26)23-15-4-7-22-10-14(15)21)13(11-30-17)12-5-8-25(9-6-12)20(28)29-2/h4,7,10-12H,3,5-6,8-9H2,1-2H3,(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50042036 (CHEMBL3360170) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C1CCCN(C1)C(=O)OC Show InChI InChI=1S/C20H22FN5O3S/c1-3-26-18(27)17-16(24-19(26)23-15-6-7-22-9-14(15)21)13(11-30-17)12-5-4-8-25(10-12)20(28)29-2/h6-7,9,11-12H,3-5,8,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE5A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042040 (CHEMBL3360166) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C(C)O Show InChI InChI=1S/C15H15FN4O2S/c1-3-20-14(22)13-12(9(7-23-13)8(2)21)19-15(20)18-11-4-5-17-6-10(11)16/h4-8,21H,3H2,1-2H3,(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042043 (CHEMBL3360163) Show SMILES CCn1c(Nc2ccncc2)nc2ccsc2c1=O Show InChI InChI=1S/C13H12N4OS/c1-2-17-12(18)11-10(5-8-19-11)16-13(17)15-9-3-6-14-7-4-9/h3-8H,2H2,1H3,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50042041 (CHEMBL3360165) Show SMILES CCn1c(Nc2ccncc2F)nc2c(csc2c1=O)C#N Show InChI InChI=1S/C14H10FN5OS/c1-2-20-13(21)12-11(8(5-16)7-22-12)19-14(20)18-10-3-4-17-6-9(10)15/h3-4,6-7H,2H2,1H3,(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216517 (3-(2-biphenyl-4-ylmethyl-3-oxo-2,3-dihydro-1H-isoi...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccc(cc3)-c3ccccc3)C(=O)c2c1 Show InChI InChI=1S/C24H20N2O3/c27-23(25-29)13-9-17-6-12-21-16-26(24(28)22(21)14-17)15-18-7-10-20(11-8-18)19-4-2-1-3-5-19/h1-14,29H,15-16H2,(H,25,27)/b13-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216519 (3-(2-(4-tert-butylbenzyl)-3-oxoisoindolin-5-yl)-N-...) Show SMILES CC(C)(C)c1ccc(CN2Cc3ccc(\C=C\C(=O)NO)cc3C2=O)cc1 Show InChI InChI=1S/C22H24N2O3/c1-22(2,3)18-9-5-16(6-10-18)13-24-14-17-8-4-15(7-11-20(25)23-27)12-19(17)21(24)26/h4-12,27H,13-14H2,1-3H3,(H,23,25)/b11-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042044 (CHEMBL3360162) Show SMILES CCn1c(Nc2cccnc2)nc2ccsc2c1=O Show InChI InChI=1S/C13H12N4OS/c1-2-17-12(18)11-10(5-7-19-11)16-13(17)15-9-4-3-6-14-8-9/h3-8H,2H2,1H3,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042048 (CHEMBL3360158) Show SMILES CCc1ccccc1Nc1nc2ccsc2c(=O)n1CC Show InChI InChI=1S/C16H17N3OS/c1-3-11-7-5-6-8-12(11)17-16-18-13-9-10-21-14(13)15(20)19(16)4-2/h5-10H,3-4H2,1-2H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042049 (CHEMBL3360157) Show SMILES CCn1c(Nc2ccc(C)cc2)nc2ccsc2c1=O Show InChI InChI=1S/C15H15N3OS/c1-3-18-14(19)13-12(8-9-20-13)17-15(18)16-11-6-4-10(2)5-7-11/h4-9H,3H2,1-2H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042050 (CHEMBL3360156) Show SMILES CCn1c(Nc2cccc(C)c2)nc2ccsc2c1=O Show InChI InChI=1S/C15H15N3OS/c1-3-18-14(19)13-12(7-8-20-13)17-15(18)16-11-6-4-5-10(2)9-11/h4-9H,3H2,1-2H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216516 (3-(2-(4-(pyridin-4-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc3ccc(cc3)-c3ccncc3)C(=O)c2c1 Show InChI InChI=1S/C23H19N3O3/c27-22(25-29)8-4-16-1-7-20-15-26(23(28)21(20)13-16)14-17-2-5-18(6-3-17)19-9-11-24-12-10-19/h1-13,29H,14-15H2,(H,25,27)/b8-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50042047 (CHEMBL3360159) Show SMILES CCn1c(Nc2ccccc2C#N)nc2ccsc2c1=O Show InChI InChI=1S/C15H12N4OS/c1-2-19-14(20)13-12(7-8-21-13)18-15(19)17-11-6-4-3-5-10(11)9-16/h3-8H,2H2,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair

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