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Compile Data Set for Download or QSAR

Found 42 hits with Last Name = 'oishi' and Initial = 't'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
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n/an/a 0.820n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor beta


(Homo sapiens (Human))		BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
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n/an/a 1.60n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen-related receptor gamma


(Homo sapiens (Human))		BDBM29608
PNG
(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Show SMILES CC(C)(c1ccc(O)cc1)c1ccc(O)cc1
Show InChI InChI=1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3
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n/an/a 4.90n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Binding affinity to human ERRgamma

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen-related receptor gamma


(Homo sapiens (Human))		BDBM20607
PNG
((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
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n/an/a 62n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Binding affinity to human ERRgamma

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM20607
PNG
((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
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n/an/a 80n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50261553
PNG
(CHEMBL4087989)
Show SMILES Cl.Oc1ccc2cc3nc4ccccc4c(-c4ccccc4)c3cc2c1
Show InChI InChI=1S/C23H15NO/c25-18-11-10-16-14-22-20(13-17(16)12-18)23(15-6-2-1-3-7-15)19-8-4-5-9-21(19)24-22/h1-14,25H
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n/an/a 154n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261553
PNG
(CHEMBL4087989)
Show SMILES Cl.Oc1ccc2cc3nc4ccccc4c(-c4ccccc4)c3cc2c1
Show InChI InChI=1S/C23H15NO/c25-18-11-10-16-14-22-20(13-17(16)12-18)23(15-6-2-1-3-7-15)19-8-4-5-9-21(19)24-22/h1-14,25H
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n/an/a 169n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM20607
PNG
((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
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n/an/a 226n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261555
PNG
(CHEMBL4088694)
Show SMILES Cl.Oc1ccc2c(-c3ccccc3)c3cc4ccccc4cc3nc2c1
Show InChI InChI=1S/C23H15NO/c25-18-10-11-19-22(14-18)24-21-13-17-9-5-4-8-16(17)12-20(21)23(19)15-6-2-1-3-7-15/h1-14,25H
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n/an/a 294n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50261555
PNG
(CHEMBL4088694)
Show SMILES Cl.Oc1ccc2c(-c3ccccc3)c3cc4ccccc4cc3nc2c1
Show InChI InChI=1S/C23H15NO/c25-18-10-11-19-22(14-18)24-21-13-17-9-5-4-8-16(17)12-20(21)23(19)15-6-2-1-3-7-15/h1-14,25H
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n/an/a 306n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM20607
PNG
((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
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n/an/a 341n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261551
PNG
(CHEMBL4094003)
Show SMILES Cl.c1ccc(cc1)-c1c2ccccc2nc2cc3ccccc3cc12
Show InChI InChI=1S/C23H15N/c1-2-8-16(9-3-1)23-19-12-6-7-13-21(19)24-22-15-18-11-5-4-10-17(18)14-20(22)23/h1-15H
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n/an/a 915n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50261554
PNG
(CHEMBL4092300)
Show SMILES Cl.Oc1cccc2c(-c3ccccc3)c3cc4ccccc4cc3nc12
Show InChI InChI=1S/C23H15NO/c25-21-12-6-11-18-22(15-7-2-1-3-8-15)19-13-16-9-4-5-10-17(16)14-20(19)24-23(18)21/h1-14,25H
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n/an/a 939n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261554
PNG
(CHEMBL4092300)
Show SMILES Cl.Oc1cccc2c(-c3ccccc3)c3cc4ccccc4cc3nc12
Show InChI InChI=1S/C23H15NO/c25-21-12-6-11-18-22(15-7-2-1-3-8-15)19-13-16-9-4-5-10-17(16)14-20(19)24-23(18)21/h1-14,25H
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n/an/a 1.08E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM20607
PNG
((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
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n/an/a 1.53E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERbeta (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene ...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261556
PNG
(CHEMBL4105062)
Show SMILES Cl.Clc1ccc2c(-c3ccccc3)c3cc4ccccc4cc3nc2c1
Show InChI InChI=1S/C23H14ClN/c24-18-10-11-19-22(14-18)25-21-13-17-9-5-4-8-16(17)12-20(21)23(19)15-6-2-1-3-7-15/h1-14H
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n/an/a 1.65E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261557
PNG
(CHEMBL4071813)
Show SMILES Cl.Clc1c2ccccc2cc2c(-c3ccccc3)c3ccccc3nc12
Show InChI InChI=1S/C23H14ClN/c24-22-17-11-5-4-10-16(17)14-19-21(15-8-2-1-3-9-15)18-12-6-7-13-20(18)25-23(19)22/h1-14H
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n/an/a 1.68E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50261551
PNG
(CHEMBL4094003)
Show SMILES Cl.c1ccc(cc1)-c1c2ccccc2nc2cc3ccccc3cc12
Show InChI InChI=1S/C23H15N/c1-2-8-16(9-3-1)23-19-12-6-7-13-21(19)24-22-15-18-11-5-4-10-17(18)14-20(22)23/h1-15H
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n/an/a 1.69E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50261556
PNG
(CHEMBL4105062)
Show SMILES Cl.Clc1ccc2c(-c3ccccc3)c3cc4ccccc4cc3nc2c1
Show InChI InChI=1S/C23H14ClN/c24-18-10-11-19-22(14-18)25-21-13-17-9-5-4-8-16(17)12-20(21)23(19)15-6-2-1-3-7-15/h1-14H
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n/an/a 1.98E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50261557
PNG
(CHEMBL4071813)
Show SMILES Cl.Clc1c2ccccc2cc2c(-c3ccccc3)c3ccccc3nc12
Show InChI InChI=1S/C23H14ClN/c24-22-17-11-5-4-10-16(17)14-19-21(15-8-2-1-3-9-15)18-12-6-7-13-20(18)25-23(19)22/h1-14H
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n/an/a 2.53E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261558
PNG
(CHEMBL4071506)
Show SMILES Cl.FC(F)(F)c1cccc2c(-c3ccccc3)c3cc4ccccc4cc3nc12
Show InChI InChI=1S/C24H14F3N/c25-24(26,27)20-12-6-11-18-22(15-7-2-1-3-8-15)19-13-16-9-4-5-10-17(16)14-21(19)28-23(18)20/h1-14H
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n/an/a 2.65E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261552
PNG
(CHEMBL4066690)
Show SMILES Cl.FC(F)(F)c1ccc2cc3nc4ccccc4c(-c4ccccc4)c3cc2c1
Show InChI InChI=1S/C24H14F3N/c25-24(26,27)18-11-10-16-14-22-20(13-17(16)12-18)23(15-6-2-1-3-7-15)19-8-4-5-9-21(19)28-22/h1-14H
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n/an/a 3.51E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261552
PNG
(CHEMBL4066690)
Show SMILES Cl.FC(F)(F)c1ccc2cc3nc4ccccc4c(-c4ccccc4)c3cc2c1
Show InChI InChI=1S/C24H14F3N/c25-24(26,27)18-11-10-16-14-22-20(13-17(16)12-18)23(15-6-2-1-3-7-15)19-8-4-5-9-21(19)28-22/h1-14H
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n/an/a 5.34E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261551
PNG
(CHEMBL4094003)
Show SMILES Cl.c1ccc(cc1)-c1c2ccccc2nc2cc3ccccc3cc12
Show InChI InChI=1S/C23H15N/c1-2-8-16(9-3-1)23-19-12-6-7-13-21(19)24-22-15-18-11-5-4-10-17(18)14-20(22)23/h1-15H
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n/an/a 9.39E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261555
PNG
(CHEMBL4088694)
Show SMILES Cl.Oc1ccc2c(-c3ccccc3)c3cc4ccccc4cc3nc2c1
Show InChI InChI=1S/C23H15NO/c25-18-10-11-19-22(14-18)24-21-13-17-9-5-4-8-16(17)12-20(21)23(19)15-6-2-1-3-7-15/h1-14,25H
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n/an/an/an/a 7.40E+3n/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Ras-related protein Rap-1A


(Homo sapiens (Human))		BDBM50310364
PNG
(CHEMBL1077126 | YESSOTOXIN)
Show SMILES C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](OS([O-])(=O)=O)[C@@](C)(CCOS([O-])(=O)=O)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)C[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Show InChI InChI=1S/C55H82O20S2/c1-10-11-29(2)12-15-51(5,56)50-31(4)20-41-40(71-50)25-45-55(9,73-41)28-44-38(68-45)24-43-49(70-44)30(3)13-16-53(7)47(69-43)27-46-54(8,75-53)17-14-32-33(67-46)21-35-34(64-32)22-36-37(65-35)23-42-39(66-36)26-48(74-77(60,61)62)52(6,72-42)18-19-63-76(57,58)59/h10,12,15,30,32-50,56H,1-2,4,11,13-14,16-28H2,3,5-9H3,(H,57,58,59)(H,60,61,62)/p-2/b15-12+/t30-,32-,33+,34+,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47+,48-,49+,50-,51+,52+,53-,54+,55+/m0/s1
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n/an/an/a 4.00E+3n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to RAP1A in human RBC membrane by surface plasmon resonance analysis

Bioorg Med Chem Lett 20: 6443-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.080
BindingDB Entry DOI: 10.7270/Q2R212C8
More data for this
Ligand-Target Pair
Ras-related protein Rap-1A


(Homo sapiens (Human))		BDBM50310364
PNG
(CHEMBL1077126 | YESSOTOXIN)
Show SMILES C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](OS([O-])(=O)=O)[C@@](C)(CCOS([O-])(=O)=O)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)C[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Show InChI InChI=1S/C55H82O20S2/c1-10-11-29(2)12-15-51(5,56)50-31(4)20-41-40(71-50)25-45-55(9,73-41)28-44-38(68-45)24-43-49(70-44)30(3)13-16-53(7)47(69-43)27-46-54(8,75-53)17-14-32-33(67-46)21-35-34(64-32)22-36-37(65-35)23-42-39(66-36)26-48(74-77(60,61)62)52(6,72-42)18-19-63-76(57,58)59/h10,12,15,30,32-50,56H,1-2,4,11,13-14,16-28H2,3,5-9H3,(H,57,58,59)(H,60,61,62)/p-2/b15-12+/t30-,32-,33+,34+,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47+,48-,49+,50-,51+,52+,53-,54+,55+/m0/s1
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n/an/an/a 4.00E+3n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to RAP1A in human RBC membrane by western blot analysis

Bioorg Med Chem Lett 20: 6443-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.080
BindingDB Entry DOI: 10.7270/Q2R212C8
More data for this
Ligand-Target Pair
Ras-related protein Rap-1A


(Homo sapiens (Human))		BDBM50330178
PNG
(CHEMBL1269578 | desulfo-Yessotoxin)
Show SMILES C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](O)[C@@](C)(CCO)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)[C@H](O)[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Show InChI InChI=1S/C55H82O15/c1-10-11-28(2)12-15-51(5,59)50-30(4)20-39-38(66-50)26-46-55(9,69-39)49(58)48-42(65-46)24-41-47(67-48)29(3)13-16-53(7)45(64-41)27-44-54(8,70-53)17-14-31-32(63-44)21-34-33(60-31)22-35-36(61-34)23-40-37(62-35)25-43(57)52(6,68-40)18-19-56/h10,12,15,29,31-50,56-59H,1-2,4,11,13-14,16-27H2,3,5-9H3/b15-12+/t29-,31-,32+,33+,34-,35-,36+,37+,38+,39-,40-,41-,42+,43-,44-,45+,46-,47+,48+,49+,50-,51+,52+,53-,54+,55-/m0/s1
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n/an/an/a 500n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to RAP1A in human RBC membrane by surface plasmon resonance analysis with inverted configuration

Bioorg Med Chem Lett 20: 6443-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.080
BindingDB Entry DOI: 10.7270/Q2R212C8
More data for this
Ligand-Target Pair
Glycophorin-A


(Homo sapiens (Human))		BDBM50310365
PNG
(CHEMBL1077121 | desulfated yessotoxin)
Show SMILES C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](O)[C@@](C)(CCO)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)C[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Show InChI InChI=1S/C55H82O14/c1-10-11-29(2)12-15-51(5,58)50-31(4)20-41-40(66-50)26-46-55(9,68-41)28-44-38(63-46)24-43-49(65-44)30(3)13-16-53(7)48(64-43)27-47-54(8,69-53)17-14-32-33(62-47)21-35-34(59-32)22-36-37(60-35)23-42-39(61-36)25-45(57)52(6,67-42)18-19-56/h10,12,15,30,32-50,56-58H,1-2,4,11,13-14,16-28H2,3,5-9H3/b15-12+/t30-,32-,33+,34+,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47-,48+,49+,50-,51+,52+,53-,54+,55+/m0/s1
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n/an/an/a 2.70E+5n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to transmembrane alpha-helix of glycophorin A by surface plasmon resonance method

Bioorg Med Chem Lett 18: 6115-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.020
BindingDB Entry DOI: 10.7270/Q2P55PFJ
More data for this
Ligand-Target Pair
Glycophorin-A


(Homo sapiens (Human))		BDBM50246050
PNG
((2R,3S,5R,6S)-5-(benzyloxy)-6-(benzyloxymethyl)-2-...)
Show SMILES OC[C@H]1O[C@@H](COCc2ccccc2)[C@@H](C[C@@H]1O)OCc1ccccc1 |r|
Show InChI InChI=1S/C21H26O5/c22-12-20-18(23)11-19(25-14-17-9-5-2-6-10-17)21(26-20)15-24-13-16-7-3-1-4-8-16/h1-10,18-23H,11-15H2/t18-,19+,20+,21-/m0/s1
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n/an/an/a 2.40E+6n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to transmembrane alpha-helix of glycophorin A by surface plasmon resonance method

Bioorg Med Chem Lett 18: 6115-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.020
BindingDB Entry DOI: 10.7270/Q2P55PFJ
More data for this
Ligand-Target Pair
Glycophorin-A


(Homo sapiens (Human))		BDBM50246051
PNG
((2R,3S,4aR,5aS,6aR,8S,9R,10aS,11aR,13aS)-9-Benzylo...)
Show SMILES C[C@@]12CC[C@@H]3O[C@H](CO)[C@@H](O)C[C@H]3O[C@H]1C[C@H]1O[C@@H](COCc3ccccc3)[C@@H](C[C@@H]1O2)OCc1ccccc1 |r|
Show InChI InChI=1S/C32H42O8/c1-32-13-12-24-26(14-23(34)29(17-33)37-24)39-31(32)16-27-28(40-32)15-25(36-19-22-10-6-3-7-11-22)30(38-27)20-35-18-21-8-4-2-5-9-21/h2-11,23-31,33-34H,12-20H2,1H3/t23-,24-,25+,26+,27+,28-,29+,30-,31-,32+/m0/s1
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n/an/an/a 2.40E+5n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to transmembrane alpha-helix of glycophorin A by surface plasmon resonance method

Bioorg Med Chem Lett 18: 6115-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.020
BindingDB Entry DOI: 10.7270/Q2P55PFJ
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261553
PNG
(CHEMBL4087989)
Show SMILES Cl.Oc1ccc2cc3nc4ccccc4c(-c4ccccc4)c3cc2c1
Show InChI InChI=1S/C23H15NO/c25-18-11-10-16-14-22-20(13-17(16)12-18)23(15-6-2-1-3-7-15)19-8-4-5-9-21(19)24-22/h1-14,25H
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n/an/an/an/a 1.44E+3n/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Glycophorin-A


(Homo sapiens (Human))		BDBM50310364
PNG
(CHEMBL1077126 | YESSOTOXIN)
Show SMILES C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](OS([O-])(=O)=O)[C@@](C)(CCOS([O-])(=O)=O)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)C[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Show InChI InChI=1S/C55H82O20S2/c1-10-11-29(2)12-15-51(5,56)50-31(4)20-41-40(71-50)25-45-55(9,73-41)28-44-38(68-45)24-43-49(70-44)30(3)13-16-53(7)47(69-43)27-46-54(8,75-53)17-14-32-33(67-46)21-35-34(64-32)22-36-37(65-35)23-42-39(66-36)26-48(74-77(60,61)62)52(6,72-42)18-19-63-76(57,58)59/h10,12,15,30,32-50,56H,1-2,4,11,13-14,16-28H2,3,5-9H3,(H,57,58,59)(H,60,61,62)/p-2/b15-12+/t30-,32-,33+,34+,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47+,48-,49+,50-,51+,52+,53-,54+,55+/m0/s1
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n/an/an/a 1.20E+5n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to transmembrane alpha-helix of glycophorin A by surface plasmon resonance method

Bioorg Med Chem Lett 18: 6115-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.020
BindingDB Entry DOI: 10.7270/Q2P55PFJ
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50246052
PNG
((1S,3R,5S,7R,9S,10R,12S,14R,17S,19R,21S,23R,25S,26...)
Show SMILES C[C@@]12CC[C@@H]3O[C@@H]4C[C@@H]5O[C@@H]6C[C@H](O)[C@@H](CO)O[C@H]6CC[C@@]5(C)O[C@H]4C[C@H]3O[C@H]1C[C@H]1O[C@@H](CCOCc3ccccc3)[C@@H](C[C@@H]1O2)OCc1ccccc1 |r|
Show InChI InChI=1S/C44H60O11/c1-43-16-13-30-34(19-29(46)40(24-45)51-30)52-41(43)23-37-39(55-43)21-35-31(49-37)14-17-44(2)42(53-35)22-36-38(54-44)20-33(48-26-28-11-7-4-8-12-28)32(50-36)15-18-47-25-27-9-5-3-6-10-27/h3-12,29-42,45-46H,13-26H2,1-2H3/t29-,30-,31-,32-,33+,34+,35+,36+,37+,38-,39-,40+,41-,42-,43+,44+/m0/s1
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n/an/an/a 4.80E+3n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant PDE4D by surface plasmon resonance assay

Bioorg Med Chem Lett 19: 2824-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.103
BindingDB Entry DOI: 10.7270/Q2C53KZG
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50310369
PNG
((2R,3S,4aR,5aS,6aR,8S,9R,10aS,11aR,13aS)-9-Benzylo...)
Show SMILES C[C@@]12CC[C@@H]3O[C@H](CO)[C@@H](O)C[C@H]3O[C@H]1C[C@H]1O[C@@H](CCOCc3ccccc3)[C@@H](C[C@@H]1O2)OCc1ccccc1 |r|
Show InChI InChI=1S/C33H44O8/c1-33-14-12-25-28(16-24(35)31(19-34)39-25)40-32(33)18-29-30(41-33)17-27(37-21-23-10-6-3-7-11-23)26(38-29)13-15-36-20-22-8-4-2-5-9-22/h2-11,24-32,34-35H,12-21H2,1H3/t24-,25-,26-,27+,28+,29+,30-,31+,32-,33+/m0/s1
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n/an/an/a 1.10E+4n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant PDE4D by surface plasmon resonance assay

Bioorg Med Chem Lett 19: 2824-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.103
BindingDB Entry DOI: 10.7270/Q2C53KZG
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50310368
PNG
((2R,3S,4aR,5aS,6aR,8S,9R,10aS,11aR,13aS)-8-(2-Hydr...)
Show SMILES C[C@@]12CC[C@@H]3O[C@H](CO)[C@@H](O)C[C@H]3O[C@H]1C[C@H]1O[C@@H](CCO)[C@H](O)C[C@@H]1O2 |r|
Show InChI InChI=1S/C19H32O8/c1-19-4-2-13-14(6-11(23)17(9-21)25-13)26-18(19)8-15-16(27-19)7-10(22)12(24-15)3-5-20/h10-18,20-23H,2-9H2,1H3/t10-,11+,12+,13+,14-,15-,16+,17-,18+,19-/m1/s1
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n/an/an/a 2.90E+4n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant PDE4D by surface plasmon resonance assay

Bioorg Med Chem Lett 19: 2824-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.103
BindingDB Entry DOI: 10.7270/Q2C53KZG
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50310367
PNG
((2R,3S,5R,6S)-5-(benzyloxy)-6-(2-(benzyloxy)ethyl)...)
Show SMILES OC[C@H]1O[C@@H](CCOCc2ccccc2)[C@@H](C[C@@H]1O)OCc1ccccc1 |r|
Show InChI InChI=1S/C22H28O5/c23-14-22-19(24)13-21(26-16-18-9-5-2-6-10-18)20(27-22)11-12-25-15-17-7-3-1-4-8-17/h1-10,19-24H,11-16H2/t19-,20-,21+,22+/m0/s1
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n/an/an/a 8.00E+4n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant PDE4D by surface plasmon resonance assay

Bioorg Med Chem Lett 19: 2824-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.103
BindingDB Entry DOI: 10.7270/Q2C53KZG
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50310366
PNG
(Brevetoxin | CHEMBL1077122)
Show SMILES C[C@@H]1C[C@@H]2O[C@@H]3C[C@@H]4OC(=O)C=C(C)[C@H]4O[C@@]3(C)C[C@H]2O[C@H]2CC[C@@]3(C)O[C@@]4(C)C[C@H]5O[C@H]6C[C@H]7O[C@@]8(C)[C@@H](O)C[C@@H](CC(=C)C=O)O[C@@H]8C[C@@H]7O[C@@H]6\C=C/C[C@@H]5O[C@@H]4C[C@@H]3O[C@H]12 |r,c:59,t:11|
Show InChI InChI=1S/C49H68O14/c1-24(23-50)13-27-16-38(51)49(7)42(53-27)18-33-34(61-49)17-32-28(54-33)9-8-10-29-36(56-32)22-48(6)41(57-29)20-40-46(4,63-48)12-11-30-44(60-40)25(2)14-31-37(55-30)21-47(5)39(58-31)19-35-45(62-47)26(3)15-43(52)59-35/h8-9,15,23,25,27-42,44-45,51H,1,10-14,16-22H2,2-7H3/b9-8-/t25-,27-,28-,29+,30+,31+,32+,33+,34-,35+,36-,37-,38+,39-,40+,41-,42-,44-,45-,46-,47+,48+,49+/m1/s1
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n/an/an/a 3.80E+3n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant PDE4D by surface plasmon resonance assay

Bioorg Med Chem Lett 19: 2824-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.103
BindingDB Entry DOI: 10.7270/Q2C53KZG
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50310365
PNG
(CHEMBL1077121 | desulfated yessotoxin)
Show SMILES C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](O)[C@@](C)(CCO)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)C[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Show InChI InChI=1S/C55H82O14/c1-10-11-29(2)12-15-51(5,58)50-31(4)20-41-40(66-50)26-46-55(9,68-41)28-44-38(63-46)24-43-49(65-44)30(3)13-16-53(7)48(64-43)27-47-54(8,69-53)17-14-32-33(62-47)21-35-34(59-32)22-36-37(60-35)23-42-39(61-36)25-45(57)52(6,67-42)18-19-56/h10,12,15,30,32-50,56-58H,1-2,4,11,13-14,16-28H2,3,5-9H3/b15-12+/t30-,32-,33+,34+,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47-,48+,49+,50-,51+,52+,53-,54+,55+/m0/s1
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n/an/an/a 2.00E+3n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant PDE4D by surface plasmon resonance assay

Bioorg Med Chem Lett 19: 2824-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.103
BindingDB Entry DOI: 10.7270/Q2C53KZG
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50310364
PNG
(CHEMBL1077126 | YESSOTOXIN)
Show SMILES C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](OS([O-])(=O)=O)[C@@](C)(CCOS([O-])(=O)=O)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)C[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Show InChI InChI=1S/C55H82O20S2/c1-10-11-29(2)12-15-51(5,56)50-31(4)20-41-40(71-50)25-45-55(9,73-41)28-44-38(68-45)24-43-49(70-44)30(3)13-16-53(7)47(69-43)27-46-54(8,75-53)17-14-32-33(67-46)21-35-34(64-32)22-36-37(65-35)23-42-39(66-36)26-48(74-77(60,61)62)52(6,72-42)18-19-63-76(57,58)59/h10,12,15,30,32-50,56H,1-2,4,11,13-14,16-28H2,3,5-9H3,(H,57,58,59)(H,60,61,62)/p-2/b15-12+/t30-,32-,33+,34+,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47+,48-,49+,50-,51+,52+,53-,54+,55+/m0/s1
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n/an/an/a 1.00E+3n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant PDE4D by surface plasmon resonance assay

Bioorg Med Chem Lett 19: 2824-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.103
BindingDB Entry DOI: 10.7270/Q2C53KZG
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50261554
PNG
(CHEMBL4092300)
Show SMILES Cl.Oc1cccc2c(-c3ccccc3)c3cc4ccccc4cc3nc12
Show InChI InChI=1S/C23H15NO/c25-21-12-6-11-18-22(15-7-2-1-3-8-15)19-13-16-9-4-5-10-17(16)14-20(19)24-23(18)21/h1-14,25H
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n/an/an/an/a 1.33E+3n/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...

Bioorg Med Chem 25: 5216-5237 (2017)


Article DOI: 10.1016/j.bmc.2017.07.067
BindingDB Entry DOI: 10.7270/Q26H4KVD
More data for this
Ligand-Target Pair
Glycophorin-A


(Homo sapiens (Human))		BDBM50246052
PNG
((1S,3R,5S,7R,9S,10R,12S,14R,17S,19R,21S,23R,25S,26...)
Show SMILES C[C@@]12CC[C@@H]3O[C@@H]4C[C@@H]5O[C@@H]6C[C@H](O)[C@@H](CO)O[C@H]6CC[C@@]5(C)O[C@H]4C[C@H]3O[C@H]1C[C@H]1O[C@@H](CCOCc3ccccc3)[C@@H](C[C@@H]1O2)OCc1ccccc1 |r|
Show InChI InChI=1S/C44H60O11/c1-43-16-13-30-34(19-29(46)40(24-45)51-30)52-41(43)23-37-39(55-43)21-35-31(49-37)14-17-44(2)42(53-35)22-36-38(54-44)20-33(48-26-28-11-7-4-8-12-28)32(50-36)15-18-47-25-27-9-5-3-6-10-27/h3-12,29-42,45-46H,13-26H2,1-2H3/t29-,30-,31-,32-,33+,34+,35+,36+,37+,38-,39-,40+,41-,42-,43+,44+/m0/s1
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n/an/an/a 4.80E+4n/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Binding affinity to transmembrane alpha-helix of glycophorin A by surface plasmon resonance method

Bioorg Med Chem Lett 18: 6115-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.020
BindingDB Entry DOI: 10.7270/Q2P55PFJ
More data for this
Ligand-Target Pair