BindingDB PrimarySearch

Found 32 hits with Last Name = 'olesiak' and Initial = 'm'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM19264 ((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM19267 (CHEMBL392204 \| Mycophenolic Adenine Dinucleotide (...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50192467 (CHEMBL384114 \| P1-[7-hydroxy-6-(ethyl-2-yl)-5-meth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH1				J Med Chem 49: 5018-22 (2006) Article DOI: 10.1021/jm060479r BindingDB Entry DOI: 10.7270/Q2PZ58GZ
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50192467 (CHEMBL384114 \| P1-[7-hydroxy-6-(ethyl-2-yl)-5-meth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH2				J Med Chem 49: 5018-22 (2006) Article DOI: 10.1021/jm060479r BindingDB Entry DOI: 10.7270/Q2PZ58GZ
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM19264 ((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM19267 (CHEMBL392204 \| Mycophenolic Adenine Dinucleotide (...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50192469 (CHEMBL215311 \| P1-(adenosin-5'-yl)methylenephospho...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH2				J Med Chem 49: 5018-22 (2006) Article DOI: 10.1021/jm060479r BindingDB Entry DOI: 10.7270/Q2PZ58GZ
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM19266 (CHEMBL410745 \| Mycophenolic Adenine Dinucleotide (...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50192469 (CHEMBL215311 \| P1-(adenosin-5'-yl)methylenephospho...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH1				J Med Chem 49: 5018-22 (2006) Article DOI: 10.1021/jm060479r BindingDB Entry DOI: 10.7270/Q2PZ58GZ
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM19266 (CHEMBL410745 \| Mycophenolic Adenine Dinucleotide (...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263243 (CHEMBL446927 \| N-(((2R,3S,4R,5R)-5-(6-amino-9H-pur...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263245 (CHEMBL389392 \| N-(((2R,3S,4R,5R)-5-(6-amino-2-ethy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM19265 (C2-Mycophenolic Adenine Dinucleotide (C2-MDA) \| CH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263244 (CHEMBL510826 \| N-(((2R,3S,4R,5R)-5-(6-amino-2-phen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM19265 (C2-Mycophenolic Adenine Dinucleotide (C2-MDA) \| CH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263243 (CHEMBL446927 \| N-(((2R,3S,4R,5R)-5-(6-amino-9H-pur...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263246 (CHEMBL444916 \| N-(((2R,3S,4R,5R)-5-(6-amino-2-ethy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263245 (CHEMBL389392 \| N-(((2R,3S,4R,5R)-5-(6-amino-2-ethy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263244 (CHEMBL510826 \| N-(((2R,3S,4R,5R)-5-(6-amino-2-phen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263246 (CHEMBL444916 \| N-(((2R,3S,4R,5R)-5-(6-amino-2-ethy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263248 (7-hydroxy-6-(2-hydroxyethyl)-5-methoxy-4-methyliso...) Show SMILES COc1c(C)c2COC(=O)c2c(O)c1CCO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263247 (CHEMBL476562 \| Mycophenolic bis(sulfonamide)) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263248 (7-hydroxy-6-(2-hydroxyethyl)-5-methoxy-4-methyliso...) Show SMILES COc1c(C)c2COC(=O)c2c(O)c1CCO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263247 (CHEMBL476562 \| Mycophenolic bis(sulfonamide)) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263249 (Adenosine 5'-methylenebis(sulfonamide) \| CHEMBL476...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263249 (Adenosine 5'-methylenebis(sulfonamide) \| CHEMBL476...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50370476 (Combivir \| ZIDOVUDINE TRIPHOSPHATE) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Tested against HIV-1 reverse transcriptase (HIV-1 RT) with poly(rA)/(dT)12-18 as template and [methyl-3H]-dTTP as competing substrate				J Med Chem 37: 3850-4 (1994) BindingDB Entry DOI: 10.7270/Q2PV6M05
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50030274 (1-[4-azido-5'-O-(1,1-Dithiotriphosphate)-methyl-(2...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Tested against HIV-1 reverse transcriptase (HIV-1 RT) with poly(rA)/(dT)12-18 as template and [methyl-3H]-dTTP as competing substrate				J Med Chem 37: 3850-4 (1994) BindingDB Entry DOI: 10.7270/Q2PV6M05
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50263242 (2-{(2R,3R,4S,5R)-5-[({[(2R,3S,4R,5R)-5-(6-Amino-pu...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 2				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50263242 (2-{(2R,3R,4S,5R)-5-[({[(2R,3S,4R,5R)-5-(6-Amino-pu...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMP dehydrogenase 1				Bioorg Med Chem 16: 7462-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.003 BindingDB Entry DOI: 10.7270/Q25D8RPD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair