Found 12 hits with Last Name = 'passariello' and Initial = 'c' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50002747
(CHEMBL217546)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-6-4-10(5-7-11)12-9-14(21)18-15(17-12)23-8-2-1-3-13(20)19-22/h4-7,9,22H,1-3,8H2,(H,19,20)(H,17,18,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD1-A (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50002746
(CHEMBL217545)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-5-3-4-10(8-11)12-9-14(21)18-15(17-12)23-7-2-1-6-13(20)19-22/h3-5,8-9,22H,1-2,6-7H2,(H,19,20)(H,17,18,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.65 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD1-A (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase
(Zea mays) | BDBM50002746
(CHEMBL217545)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-5-3-4-10(8-11)12-9-14(21)18-15(17-12)23-7-2-1-6-13(20)19-22/h3-5,8-9,22H,1-2,6-7H2,(H,19,20)(H,17,18,21) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD1-B (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase
(Zea mays) | BDBM50002747
(CHEMBL217546)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-6-4-10(5-7-11)12-9-14(21)18-15(17-12)23-8-2-1-3-13(20)19-22/h4-7,9,22H,1-3,8H2,(H,19,20)(H,17,18,21) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD1-B (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase 2b
(Zea mays) | BDBM50002746
(CHEMBL217545)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-5-3-4-10(8-11)12-9-14(21)18-15(17-12)23-7-2-1-6-13(20)19-22/h3-5,8-9,22H,1-2,6-7H2,(H,19,20)(H,17,18,21) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD2 (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase 2b
(Zea mays) | BDBM50002747
(CHEMBL217546)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-6-4-10(5-7-11)12-9-14(21)18-15(17-12)23-8-2-1-3-13(20)19-22/h4-7,9,22H,1-3,8H2,(H,19,20)(H,17,18,21) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD2 (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase
(Zea mays) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 26.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD1-B (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Mus musculus (Mouse)) | BDBM50002746
(CHEMBL217545)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-5-3-4-10(8-11)12-9-14(21)18-15(17-12)23-7-2-1-6-13(20)19-22/h3-5,8-9,22H,1-2,6-7H2,(H,19,20)(H,17,18,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 36.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of mouse HDAC1 (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase 2b
(Zea mays) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 49.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD2 (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Mus musculus (Mouse)) | BDBM50002747
(CHEMBL217546)Show InChI InChI=1S/C15H16ClN3O3S/c16-11-6-4-10(5-7-11)12-9-14(21)18-15(17-12)23-8-2-1-3-13(20)19-22/h4-7,9,22H,1-3,8H2,(H,19,20)(H,17,18,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of mouse HDAC1 (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Mus musculus (Mouse)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of mouse HDAC1 (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza
Curated by ChEMBL
| Assay Description Inhibition of maize HD1-A (mean) |
Bioorg Med Chem Lett 17: 1221-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.028 BindingDB Entry DOI: 10.7270/Q29W0H0K |
More data for this Ligand-Target Pair | |