BindingDB PrimarySearch

Found 1394 hits with Last Name = 'patel' and Initial = 'd'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410041 (CHEMBL178951) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410036 (CHEMBL179761) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0871	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410038 (CHEMBL179103) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410028 (CHEMBL359753) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410031 (CHEMBL362069) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263671 (2-(tert-butylamino)-N-(2-(4-((2,3-dihydrobenzo[b][...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263673 (6-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50326659 (3,10-dimethoxy-17-methyl-(10S)-17-azatetracyclo[7....) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity by its ability to displace [3H]DAMGO from mu receptor in homogenates of guinea pig brain				Bioorg Med Chem Lett 5: 1923-1926 (1995) Article DOI: 10.1016/0960-894X(95)00325-N BindingDB Entry DOI: 10.7270/Q2FX79XF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263621 (2-(3-cyanophenoxy)-N-(2-(4-((2,3-dihydrobenzo[b][1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263672 (2-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50285003 (3,10-dimethoxy-17-phenethyl-17-azatetracyclo[7.5.3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity by its ability to displace [3H]DAMGO from mu receptor in homogenates of guinea pig brain				Bioorg Med Chem Lett 5: 1923-1926 (1995) Article DOI: 10.1016/0960-894X(95)00325-N BindingDB Entry DOI: 10.7270/Q2FX79XF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM50084621 (BMN 673 \| Talazoparib) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of PARP2 (unknown origin) after 1 min in presence of NAD by top count analysis				Eur J Med Chem 165: 198-215 (2019) Article DOI: 10.1016/j.ejmech.2019.01.024 BindingDB Entry DOI: 10.7270/Q2Z03CPZ
Nirma University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263774 ((S)-N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmeth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002926 (CHEMBL244325) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50084621 (BMN 673 \| Talazoparib) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) after 1 min in presence of NAD by top count analysis				Eur J Med Chem 165: 198-215 (2019) Article DOI: 10.1016/j.ejmech.2019.01.024 BindingDB Entry DOI: 10.7270/Q2Z03CPZ
Nirma University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (GUINEA PIG)	BDBM50032527 (17-cyclopropylmethyl-10-ethoxy-4-hydroxy-3-methoxy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Binding affinity was evaluated by measuring the ability to displace [3H]DAMGO radioligand binding from Opioid receptor mu 1 in guinea pig brain membr...				J Med Chem 38: 3071-7 (1995) BindingDB Entry DOI: 10.7270/Q2QJ7HZ2
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50446130 (AG-014699 \| AG-14447 \| RUCAPARIB CAMSYLATE \| Rucap...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length PARP1 after 4 mins by [32P]NAD+ incorporation assay				Eur J Med Chem 165: 198-215 (2019) Article DOI: 10.1016/j.ejmech.2019.01.024 BindingDB Entry DOI: 10.7270/Q2Z03CPZ
Nirma University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002913 (CHEMBL389783) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410042 (CHEMBL366431) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50326659 (3,10-dimethoxy-17-methyl-(10S)-17-azatetracyclo[7....) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity by its ability to displace [3H]-U-69,593 from kappa receptor in homogenates of guinea pig brain				Bioorg Med Chem Lett 5: 1923-1926 (1995) Article DOI: 10.1016/0960-894X(95)00325-N BindingDB Entry DOI: 10.7270/Q2FX79XF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410032 (CHEMBL361980) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410045 (CHEMBL179250) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263725 (1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as inhibition of NE-induced calcium mobilizatio...				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002915 (CHEMBL389787) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263725 (1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263621 (2-(3-cyanophenoxy)-N-(2-(4-((2,3-dihydrobenzo[b][1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as inhibition of NE-induced calcium mobilizatio...				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263774 ((S)-N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmeth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as inhibition of NE-induced calcium mobilizatio...				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263724 (1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410027 (CHEMBL180816) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263620 (CHEMBL478026 \| N-(2-(4-((2,3-dihydrobenzo[b][1,4]d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50316226 ((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin)				Eur J Med Chem 165: 198-215 (2019) Article DOI: 10.1016/j.ejmech.2019.01.024 BindingDB Entry DOI: 10.7270/Q2Z03CPZ
Nirma University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002923 (CHEMBL243698) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263673 (6-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as inhibition of NE-induced calcium mobilizatio...				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002924 (CHEMBL242567) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM50316226 ((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of PARP2 (unknown origin)				Eur J Med Chem 165: 198-215 (2019) Article DOI: 10.1016/j.ejmech.2019.01.024 BindingDB Entry DOI: 10.7270/Q2Z03CPZ
Nirma University Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50032530 (17-cyclopropylmethyl-4-hydroxy-3,10-dimethoxy-17-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Binding affinity was evaluated by measuring the ability to displace [3H]U-69593 radioligand binding from Opioid receptor kappa 1 in guinea pig brain ...				J Med Chem 38: 3071-7 (1995) BindingDB Entry DOI: 10.7270/Q2QJ7HZ2
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263672 (2-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as inhibition of NE-induced calcium mobilizatio...				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410034 (CHEMBL181166) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263619 (CHEMBL477816 \| N-(2-(4-((2,3-dihydrobenzo[b][1,4]d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2C receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50263725 (1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adrenergic alpha2B receptor expressed in CHO cells assessed as inhibition of NE-induced calcium mobilization...				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50032527 (17-cyclopropylmethyl-10-ethoxy-4-hydroxy-3-methoxy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description In vivo binding affinity was evaluated by measuring the ability to displace [3H]U-69593 radioligand binding from Opioid receptor kappa 1 in guinea pi...				J Med Chem 38: 3071-7 (1995) BindingDB Entry DOI: 10.7270/Q2QJ7HZ2
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50032530 (17-cyclopropylmethyl-4-hydroxy-3,10-dimethoxy-17-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Binding affinity was evaluated by measuring the ability to displace [3H]DAMGO radioligand binding from Opioid receptor mu 1 in guinea pig brain membr...				J Med Chem 38: 3071-7 (1995) BindingDB Entry DOI: 10.7270/Q2QJ7HZ2
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002914 (CHEMBL244956) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50263724 (1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as inhibition of NE-induced calcium mobilizatio...				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002922 (CHEMBL224729) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002925 (CHEMBL244074) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50032526 (17-allyl-4-hydroxy-3,10-dimethoxy-17-azatetracyclo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Binding affinity was evaluated by measuring the ability to displace [3H]DAMGO radioligand binding from Opioid receptor mu 1 in guinea pig brain membr...				J Med Chem 38: 3071-7 (1995) BindingDB Entry DOI: 10.7270/Q2QJ7HZ2
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50410035 (CHEMBL181514) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clarkson University Curated by ChEMBL					Assay Description Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...				Bioorg Med Chem Lett 15: 3767-70 (2005) Article DOI: 10.1016/j.bmcl.2005.05.087 BindingDB Entry DOI: 10.7270/Q2SQ91KF
Clarkson University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50263620 (CHEMBL478026 \| N-(2-(4-((2,3-dihydrobenzo[b][1,4]d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human recombinant adrenergic alpha2B receptor expressed in CHO cells by radioligand binding assay				Bioorg Med Chem Lett 18: 5689-93 (2008) Article DOI: 10.1016/j.bmcl.2008.08.055 BindingDB Entry DOI: 10.7270/Q2N58M5Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50002912 (CHEMBL388911) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
James Black Foundation Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cells				J Med Chem 50: 4789-92 (2007) Checked by Author Article DOI: 10.1021/jm0707626 BindingDB Entry DOI: 10.7270/Q2Z039C3
James Black Foundation Curated by ChEMBL					More data for this Ligand-Target Pair

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