Compile Data Set for Download or QSAR

Found 1737 hits with Last Name = 'patel' and Initial = 'mv'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139889 (US8895592, 19) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OCCO)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C21H27F3N2O3S/c1-13(2)11-26-12-17(20(3,4)5)30-19(26)25-18(28)15-10-14(21(22,23)24)6-7-16(15)29-9-8-27/h6-7,10,12-13,27H,8-9,11H2,1-5H3/b25-19-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139889 (US8895592, 19) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OCCO)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C21H27F3N2O3S/c1-13(2)11-26-12-17(20(3,4)5)30-19(26)25-18(28)15-10-14(21(22,23)24)6-7-16(15)29-9-8-27/h6-7,10,12-13,27H,8-9,11H2,1-5H3/b25-19-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139900 (US8895592, 30) Show SMILES CC(C)(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1CCC#C)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C23H28F3N3O2S/c1-8-9-12-29-14-18(21(2,3)4)32-20(29)27-19(30)16-13-15(23(24,25)26)10-11-17(16)31-28-22(5,6)7/h1,10-11,13-14,28H,9,12H2,2-7H3/b27-20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139906 (US8895592, 37) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1NNC(=O)c1cccnc1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C25H28F3N5O2S/c1-5-6-12-33-15-20(24(2,3)4)36-23(33)30-22(35)18-13-17(25(26,27)28)9-10-19(18)31-32-21(34)16-8-7-11-29-14-16/h7-11,13-15,31H,5-6,12H2,1-4H3,(H,32,34)/b30-23-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139902 (US8895592, 32) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1OCC(C)(C)O)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C23H31F3N2O3S/c1-7-8-11-28-13-18(21(2,3)4)32-20(28)27-19(29)16-12-15(23(24,25)26)9-10-17(16)31-14-22(5,6)30/h9-10,12-13,30H,7-8,11,14H2,1-6H3/b27-20-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139893 (US8895592, 23) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1ONC(C)(C)C)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C23H32F3N3O2S/c1-8-9-12-29-14-18(21(2,3)4)32-20(29)27-19(30)16-13-15(23(24,25)26)10-11-17(16)31-28-22(5,6)7/h10-11,13-14,28H,8-9,12H2,1-7H3/b27-20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139907 (US8895592, 38) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1NNC(=O)c1ccncc1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C25H28F3N5O2S/c1-5-6-13-33-15-20(24(2,3)4)36-23(33)30-22(35)18-14-17(25(26,27)28)7-8-19(18)31-32-21(34)16-9-11-29-12-10-16/h7-12,14-15,31H,5-6,13H2,1-4H3,(H,32,34)/b30-23-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139887 (US8895592, 17) Show SMILES CC(C)(C)c1cn(CCC(F)(F)F)\c(=N\C(=O)c2cc(ccc2OC2CCC2)C#N)s1 Show InChI InChI=1S/C22H24F3N3O2S/c1-21(2,3)18-13-28(10-9-22(23,24)25)20(31-18)27-19(29)16-11-14(12-26)7-8-17(16)30-15-5-4-6-15/h7-8,11,13,15H,4-6,9-10H2,1-3H3/b27-20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139885 (US8895592, 15) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(Cl)ccc1OC1CC1)C(C)(C)C Show InChI InChI=1S/C21H27ClN2O2S/c1-13(2)11-24-12-18(21(3,4)5)27-20(24)23-19(25)16-10-14(22)6-9-17(16)26-15-7-8-15/h6,9-10,12-13,15H,7-8,11H2,1-5H3/b23-20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139872 (US8895592, 2) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(Cl)ccc1OCC(N)=O)C(C)(C)C Show InChI InChI=1S/C20H26ClN3O3S/c1-5-6-9-24-11-16(20(2,3)4)28-19(24)23-18(26)14-10-13(21)7-8-15(14)27-12-17(22)25/h7-8,10-11H,5-6,9,12H2,1-4H3,(H2,22,25)/b23-19-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139902 (US8895592, 32) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1OCC(C)(C)O)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C23H31F3N2O3S/c1-7-8-11-28-13-18(21(2,3)4)32-20(28)27-19(29)16-12-15(23(24,25)26)9-10-17(16)31-14-22(5,6)30/h9-10,12-13,30H,7-8,11,14H2,1-6H3/b27-20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50200028 (2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipy...) Show SMILES COc1ccccc1C1CCN(CNC(=O)c2cccc(C)c2)CC1 Show InChI InChI=1S/C21H26N2O2/c1-16-6-5-7-18(14-16)21(24)22-15-23-12-10-17(11-13-23)19-8-3-4-9-20(19)25-2/h3-9,14,17H,10-13,15H2,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 7450-65 (2006) Article DOI: 10.1021/jm060662k BindingDB Entry DOI: 10.7270/Q25X28MM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139905 (US8895592, 36) Show SMILES CCCCn1c2cccnc2sc1=NC(=O)c1cc(ccc1OC[C@H](C)O)C(F)(F)F |w:13.15| Show InChI InChI=1S/C21H22F3N3O3S/c1-3-4-10-27-16-6-5-9-25-19(16)31-20(27)26-18(29)15-11-14(21(22,23)24)7-8-17(15)30-12-13(2)28/h5-9,11,13,28H,3-4,10,12H2,1-2H3/b26-20-/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139888 (US8895592, 18) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OCCOC(C)=O)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C23H29F3N2O4S/c1-14(2)12-28-13-19(22(4,5)6)33-21(28)27-20(30)17-11-16(23(24,25)26)7-8-18(17)32-10-9-31-15(3)29/h7-8,11,13-14H,9-10,12H2,1-6H3/b27-21-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139895 (US8895592, 25) Show SMILES CCCCn1c2cnccc2s\c1=N/C(=O)c1cc(ccc1OCCNC(C)=O)C(F)(F)F Show InChI InChI=1S/C22H23F3N4O3S/c1-3-4-10-29-17-13-26-8-7-19(17)33-21(29)28-20(31)16-12-15(22(23,24)25)5-6-18(16)32-11-9-27-14(2)30/h5-8,12-13H,3-4,9-11H2,1-2H3,(H,27,30)/b28-21-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139906 (US8895592, 37) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1NNC(=O)c1cccnc1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C25H28F3N5O2S/c1-5-6-12-33-15-20(24(2,3)4)36-23(33)30-22(35)18-13-17(25(26,27)28)9-10-19(18)31-32-21(34)16-8-7-11-29-14-16/h7-11,13-15,31H,5-6,12H2,1-4H3,(H,32,34)/b30-23-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139901 (US8895592, 31) Show SMILES CC(C)(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1CC=C=C)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C23H28F3N3O2S/c1-8-9-12-29-14-18(21(2,3)4)32-20(29)27-19(30)16-13-15(23(24,25)26)10-11-17(16)31-28-22(5,6)7/h9-11,13-14,28H,1,12H2,2-7H3/b27-20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139899 (US8895592, 29) Show SMILES CCCCn1c2cnccc2s\c1=N/C(=O)c1cc(ccc1OC[C@H](C)O)C(F)(F)F Show InChI InChI=1S/C21H22F3N3O3S/c1-3-4-9-27-16-11-25-8-7-18(16)31-20(27)26-19(29)15-10-14(21(22,23)24)5-6-17(15)30-12-13(2)28/h5-8,10-11,13,28H,3-4,9,12H2,1-2H3/b26-20-/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139905 (US8895592, 36) Show SMILES CCCCn1c2cccnc2sc1=NC(=O)c1cc(ccc1OC[C@H](C)O)C(F)(F)F |w:13.15| Show InChI InChI=1S/C21H22F3N3O3S/c1-3-4-10-27-16-6-5-9-25-19(16)31-20(27)26-18(29)15-11-14(21(22,23)24)7-8-17(15)30-12-13(2)28/h5-9,11,13,28H,3-4,10,12H2,1-2H3/b26-20-/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139907 (US8895592, 38) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1NNC(=O)c1ccncc1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C25H28F3N5O2S/c1-5-6-13-33-15-20(24(2,3)4)36-23(33)30-22(35)18-14-17(25(26,27)28)7-8-19(18)31-32-21(34)16-9-11-29-12-10-16/h7-12,14-15,31H,5-6,13H2,1-4H3,(H,32,34)/b30-23-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139878 (US8895592, 8) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OCC1CCOC1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C24H31F3N2O3S/c1-15(2)11-29-12-20(23(3,4)5)33-22(29)28-21(30)18-10-17(24(25,26)27)6-7-19(18)32-14-16-8-9-31-13-16/h6-7,10,12,15-16H,8-9,11,13-14H2,1-5H3/b28-22-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139899 (US8895592, 29) Show SMILES CCCCn1c2cnccc2s\c1=N/C(=O)c1cc(ccc1OC[C@H](C)O)C(F)(F)F Show InChI InChI=1S/C21H22F3N3O3S/c1-3-4-9-27-16-11-25-8-7-18(16)31-20(27)26-19(29)15-10-14(21(22,23)24)5-6-17(15)30-12-13(2)28/h5-8,10-11,13,28H,3-4,9,12H2,1-2H3/b26-20-/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139896 (US8895592, 26) Show SMILES CC(C)(O)COc1ccc(cc1C(=O)\N=c1/sc2ccncc2n1CC1CCC1)C(F)(F)F Show InChI InChI=1S/C23H24F3N3O3S/c1-22(2,31)13-32-18-7-6-15(23(24,25)26)10-16(18)20(30)28-21-29(12-14-4-3-5-14)17-11-27-9-8-19(17)33-21/h6-11,14,31H,3-5,12-13H2,1-2H3/b28-21-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139872 (US8895592, 2) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(Cl)ccc1OCC(N)=O)C(C)(C)C Show InChI InChI=1S/C20H26ClN3O3S/c1-5-6-9-24-11-16(20(2,3)4)28-19(24)23-18(26)14-10-13(21)7-8-15(14)27-12-17(22)25/h7-8,10-11H,5-6,9,12H2,1-4H3,(H2,22,25)/b23-19-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membrane				J Med Chem 49: 7450-65 (2006) Article DOI: 10.1021/jm060662k BindingDB Entry DOI: 10.7270/Q25X28MM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139895 (US8895592, 25) Show SMILES CCCCn1c2cnccc2s\c1=N/C(=O)c1cc(ccc1OCCNC(C)=O)C(F)(F)F Show InChI InChI=1S/C22H23F3N4O3S/c1-3-4-10-29-17-13-26-8-7-19(17)33-21(29)28-20(31)16-12-15(22(23,24)25)5-6-18(16)32-11-9-27-14(2)30/h5-8,12-13H,3-4,9-11H2,1-2H3,(H,27,30)/b28-21-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (NEONATAL RAT)	BDBM50471340 (CHEMBL317912) Show SMILES Oc1cccc2C(CCCc12)c1c[nH]cn1 Show InChI InChI=1S/C13H14N2O/c16-13-6-2-3-9-10(4-1-5-11(9)13)12-7-14-8-15-12/h2-3,6-8,10,16H,1,4-5H2,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-2B adrenergic receptor of rat neonatal lung in radioligand binding assay				J Med Chem 47: 3220-35 (2004) Article DOI: 10.1021/jm030551a BindingDB Entry DOI: 10.7270/Q2HD7ZD1
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139878 (US8895592, 8) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OCC1CCOC1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C24H31F3N2O3S/c1-15(2)11-29-12-20(23(3,4)5)33-22(29)28-21(30)18-10-17(24(25,26)27)6-7-19(18)32-14-16-8-9-31-13-16/h6-7,10,12,15-16H,8-9,11,13-14H2,1-5H3/b28-22-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139874 (US8895592, 4) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(Cl)ccc1OCC1CCO1)C(C)(C)C Show InChI InChI=1S/C22H29ClN2O3S/c1-14(2)11-25-12-19(22(3,4)5)29-21(25)24-20(26)17-10-15(23)6-7-18(17)28-13-16-8-9-27-16/h6-7,10,12,14,16H,8-9,11,13H2,1-5H3/b24-21-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139886 (US8895592, 16) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OC1CCC1)C#N)C(C)(C)C Show InChI InChI=1S/C23H29N3O2S/c1-15(2)13-26-14-20(23(3,4)5)29-22(26)25-21(27)18-11-16(12-24)9-10-19(18)28-17-7-6-8-17/h9-11,14-15,17H,6-8,13H2,1-5H3/b25-22-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139891 (US8895592, 21) Show SMILES CCCCn1c2cnccc2s\c1=N/C(=O)c1cc(ccc1OCC(C)(C)O)C(F)(F)F Show InChI InChI=1S/C22H24F3N3O3S/c1-4-5-10-28-16-12-26-9-8-18(16)32-20(28)27-19(29)15-11-14(22(23,24)25)6-7-17(15)31-13-21(2,3)30/h6-9,11-12,30H,4-5,10,13H2,1-3H3/b27-20-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50193321 ((Z)-1-(3,5-difluorophenyl)-3-(4-pyridin-2-ylpipera...) Show SMILES CO\N=C(\CCN1CCN(CC1)c1ccccn1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C19H22F2N4O/c1-26-23-18(15-12-16(20)14-17(21)13-15)5-7-24-8-10-25(11-9-24)19-4-2-3-6-22-19/h2-4,6,12-14H,5,7-11H2,1H3/b23-18-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50193331 ((E)-1-(3,4-dichlorophenyl)-3-(4-pyridin-2-ylpipera...) Show SMILES CO\N=C(/CCN1CCN(CC1)c1ccccn1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H22Cl2N4O/c1-26-23-18(15-5-6-16(20)17(21)14-15)7-9-24-10-12-25(13-11-24)19-4-2-3-8-22-19/h2-6,8,14H,7,9-13H2,1H3/b23-18+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50193296 ((Z)-1-(3-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-...) Show SMILES CO\N=C(\CCN1CCN(CC1)c1ccccn1)c1cccc(F)c1 Show InChI InChI=1S/C19H23FN4O/c1-25-22-18(16-5-4-6-17(20)15-16)8-10-23-11-13-24(14-12-23)19-7-2-3-9-21-19/h2-7,9,15H,8,10-14H2,1H3/b22-18-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139893 (US8895592, 23) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1ONC(C)(C)C)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C23H32F3N3O2S/c1-8-9-12-29-14-18(21(2,3)4)32-20(29)27-19(30)16-13-15(23(24,25)26)10-11-17(16)31-28-22(5,6)7/h10-11,13-14,28H,8-9,12H2,1-7H3/b27-20-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139896 (US8895592, 26) Show SMILES CC(C)(O)COc1ccc(cc1C(=O)\N=c1/sc2ccncc2n1CC1CCC1)C(F)(F)F Show InChI InChI=1S/C23H24F3N3O3S/c1-22(2,31)13-32-18-7-6-15(23(24,25)26)10-16(18)20(30)28-21-29(12-14-4-3-5-14)17-11-27-9-8-19(17)33-21/h6-11,14,31H,3-5,12-13H2,1-2H3/b28-21-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139873 (US8895592, 3) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OCc1ccco1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C24H27F3N2O3S/c1-15(2)12-29-13-20(23(3,4)5)33-22(29)28-21(30)18-11-16(24(25,26)27)8-9-19(18)32-14-17-7-6-10-31-17/h6-11,13,15H,12,14H2,1-5H3/b28-22-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139879 (US8895592, 9) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1OC[C@@H]1CCCN1C)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C25H34F3N3O2S/c1-6-7-13-31-15-21(24(2,3)4)34-23(31)29-22(32)19-14-17(25(26,27)28)10-11-20(19)33-16-18-9-8-12-30(18)5/h10-11,14-15,18H,6-9,12-13,16H2,1-5H3/b29-23-/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50193330 ((E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)pr...) Show SMILES CO\N=C(/CCN1CCN(CC1)c1ccccn1)c1cccc(C)c1 Show InChI InChI=1S/C20H26N4O/c1-17-6-5-7-18(16-17)19(22-25-2)9-11-23-12-14-24(15-13-23)20-8-3-4-10-21-20/h3-8,10,16H,9,11-15H2,1-2H3/b22-19+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50200037 (2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1...) Show SMILES Cc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1 Show InChI InChI=1S/C19H23N3O/c1-15-5-4-6-17(13-15)21-19(23)14-22-11-8-16(9-12-22)18-7-2-3-10-20-18/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 7450-65 (2006) Article DOI: 10.1021/jm060662k BindingDB Entry DOI: 10.7270/Q25X28MM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139897 (US8895592, 27) Show SMILES CC(C)(O)COc1ccc(cc1C(=O)\N=c1/sc2ccncc2n1CCCC(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H21F6N3O3S/c1-20(2,33)12-34-16-5-4-13(22(26,27)28)10-14(16)18(32)30-19-31(9-3-7-21(23,24)25)15-11-29-8-6-17(15)35-19/h4-6,8,10-11,33H,3,7,9,12H2,1-2H3/b30-19-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139873 (US8895592, 3) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(ccc1OCc1ccco1)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C24H27F3N2O3S/c1-15(2)12-29-13-20(23(3,4)5)33-22(29)28-21(30)18-11-16(24(25,26)27)8-9-19(18)32-14-17-7-6-10-31-17/h6-11,13,15H,12,14H2,1-5H3/b28-22-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50471340 (CHEMBL317912) Show SMILES Oc1cccc2C(CCCc12)c1c[nH]cn1 Show InChI InChI=1S/C13H14N2O/c16-13-6-2-3-9-10(4-1-5-11(9)13)12-7-14-8-15-12/h2-3,6-8,10,16H,1,4-5H2,(H,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-2A adrenergic receptor of human clone in radioligand binding assay				J Med Chem 47: 3220-35 (2004) Article DOI: 10.1021/jm030551a BindingDB Entry DOI: 10.7270/Q2HD7ZD1
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 7450-65 (2006) Article DOI: 10.1021/jm060662k BindingDB Entry DOI: 10.7270/Q25X28MM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139874 (US8895592, 4) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(Cl)ccc1OCC1CCO1)C(C)(C)C Show InChI InChI=1S/C22H29ClN2O3S/c1-14(2)11-25-12-19(22(3,4)5)29-21(25)24-20(26)17-10-15(23)6-7-18(17)28-13-16-8-9-27-16/h6-7,10,12,14,16H,8-9,11,13H2,1-5H3/b24-21-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139879 (US8895592, 9) Show SMILES CCCCn1cc(s\c1=N/C(=O)c1cc(ccc1OC[C@@H]1CCCN1C)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C25H34F3N3O2S/c1-6-7-13-31-15-21(24(2,3)4)34-23(31)29-22(32)19-14-17(25(26,27)28)10-11-20(19)33-16-18-9-8-12-30(18)5/h10-11,14-15,18H,6-9,12-13,16H2,1-5H3/b29-23-/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139891 (US8895592, 21) Show SMILES CCCCn1c2cnccc2s\c1=N/C(=O)c1cc(ccc1OCC(C)(C)O)C(F)(F)F Show InChI InChI=1S/C22H24F3N3O3S/c1-4-5-10-28-16-12-26-9-8-18(16)32-20(28)27-19(29)15-11-14(22(23,24)25)6-7-17(15)31-13-21(2,3)30/h6-9,11-12,30H,4-5,10,13H2,1-3H3/b27-20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM139885 (US8895592, 15) Show SMILES CC(C)Cn1cc(s\c1=N/C(=O)c1cc(Cl)ccc1OC1CC1)C(C)(C)C Show InChI InChI=1S/C21H27ClN2O2S/c1-13(2)11-24-12-18(21(3,4)5)27-20(24)23-19(25)16-10-14(22)6-9-17(16)26-15-7-8-15/h6,9-10,12-13,15H,7-8,11H2,1-5H3/b23-20-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM139897 (US8895592, 27) Show SMILES CC(C)(O)COc1ccc(cc1C(=O)\N=c1/sc2ccncc2n1CCCC(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H21F6N3O3S/c1-20(2,33)12-34-16-5-4-13(22(26,27)28)10-14(16)18(32)30-19-31(9-3-7-21(23,24)25)15-11-29-8-6-17(15)35-19/h4-6,8,10-11,33H,3,7,9,12H2,1-2H3/b30-19-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The CB1 and CB2 radioligand binding assays described herein are utilized to ascertain the selectivity of compounds of the present application for bin...				US Patent US8895592 (2014) BindingDB Entry DOI: 10.7270/Q2CV4GDB
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50193290 ((E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)pr...) Show SMILES CO\N=C(/CCN1CCN(CC1)c1ccccn1)c1ccccc1C Show InChI InChI=1S/C20H26N4O/c1-17-7-3-4-8-18(17)19(22-25-2)10-12-23-13-15-24(16-14-23)20-9-5-6-11-21-20/h3-9,11H,10,12-16H2,1-2H3/b22-19+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membrane				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair

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