Found 104 hits with Last Name = 'pawlowski' and Initial = 'g' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hrh3 protein
(RAT) | BDBM50070214
(4-(7,7-Dimethyl-oct-3-ynyl)-1H-imidazole | CHEMBL2...)Show InChI InChI=1S/C13H20N2/c1-13(2,3)9-7-5-4-6-8-12-10-14-11-15-12/h10-11H,6-9H2,1-3H3,(H,14,15) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 0.830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM50070220
(4-(6-Cyclopentyl-hex-3-ynyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C14H20N2/c1(3-7-13-8-5-6-9-13)2-4-10-14-11-15-12-16-14/h11-13H,3-10H2,(H,15,16) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85407
(GT 2231)Show SMILES N[C@@H](CC1CCCCC1)C=CCCc1cnc[nH]1 |r,w:10.11| Show InChI InChI=1S/C15H25N3/c16-14(10-13-6-2-1-3-7-13)8-4-5-9-15-11-17-12-18-15/h4,8,11-14H,1-3,5-7,9-10,16H2,(H,17,18)/b8-4+/t14-/m1/s1 | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM22914
(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech, Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 275: 598-604 (1995)
BindingDB Entry DOI: 10.7270/Q21G0JSP |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM50070211
(4-(6-Cyclohexyl-hex-3-ynyl)-1H-imidazole | CHEMBL1...)Show InChI InChI=1S/C15H22N2/c1(2-7-11-15-12-16-13-17-15)4-8-14-9-5-3-6-10-14/h12-14H,3-11H2,(H,16,17) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM85405
(GT 2227 | GT 2228)Show InChI InChI=1S/C15H24N2/c1(2-7-11-15-12-16-13-17-15)4-8-14-9-5-3-6-10-14/h1-2,12-14H,3-11H2,(H,16,17)/b2-1- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85412
(GT 2287)Show InChI InChI=1S/C16H24N2/c1(3-8-12-16-13-17-14-18-16)2-5-9-15-10-6-4-7-11-15/h13-15H,2,4-12H2,(H,17,18) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85405
(GT 2227 | GT 2228)Show InChI InChI=1S/C15H24N2/c1(2-7-11-15-12-16-13-17-15)4-8-14-9-5-3-6-10-14/h1-2,12-14H,3-11H2,(H,16,17)/b2-1- | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85402
(GT 2327)Show InChI InChI=1S/C15H18N2/c1(2-7-11-15-12-16-13-17-15)4-8-14-9-5-3-6-10-14/h1-3,5-6,9-10,12-13H,4,7-8,11H2,(H,16,17)/b2-1- | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319488
(CHEMBL1084901 | rac-{5-Chloro-3-[2-(3,5-dimethyl-i...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccc(Cl)cc12 Show InChI InChI=1S/C24H22ClN3O5S/c1-13-19(15(3)33-26-13)11-28-24(17-6-4-5-7-21(17)34(28,31)32)23-14(2)27(12-22(29)30)20-9-8-16(25)10-18(20)23/h4-10,24H,11-12H2,1-3H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85399
(GT 2148)Show InChI InChI=1S/C15H20N4O/c16-14(7-6-12-4-2-1-3-5-12)15(20)18-9-8-13-10-17-11-19-13/h1-5,10-11,14H,6-9,16H2,(H,17,19)(H,18,20)/t14-/m0/s1 | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319486
(CHEMBL1084893 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C24H23N3O5S/c1-14-19(16(3)32-25-14)12-27-24(18-9-5-7-11-21(18)33(27,30)31)23-15(2)26(13-22(28)29)20-10-6-4-8-17(20)23/h4-11,24H,12-13H2,1-3H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162903
(CHEMBL359855 | [6-(4-Fluoro-benzenesulfonylamino)-...)Show SMILES CC1CCc2c(C1)c1cc(NS(=O)(=O)c3ccc(F)cc3)ccc1n2CC(O)=O Show InChI InChI=1S/C21H21FN2O4S/c1-13-2-8-19-17(10-13)18-11-15(5-9-20(18)24(19)12-21(25)26)23-29(27,28)16-6-3-14(22)4-7-16/h3-7,9,11,13,23H,2,8,10,12H2,1H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319487
(CHEMBL1084894 | rac-{2-Methyl-3-[2-(3-methyl-5-phe...)Show SMILES Cc1noc(c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C29H25N3O5S/c1-18-23(29(37-30-18)20-10-4-3-5-11-20)16-32-28(22-13-7-9-15-25(22)38(32,35)36)27-19(2)31(17-26(33)34)24-14-8-6-12-21(24)27/h3-15,28H,16-17H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85405
(GT 2227 | GT 2228)Show InChI InChI=1S/C15H24N2/c1(2-7-11-15-12-16-13-17-15)4-8-14-9-5-3-6-10-14/h1-2,12-14H,3-11H2,(H,16,17)/b2-1- | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 15.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85411
(GT 2174)Show InChI InChI=1S/C15H25N3O/c19-15(17-10-9-14-11-16-12-18-14)8-4-7-13-5-2-1-3-6-13/h11-13H,1-10H2,(H,16,18)(H,17,19) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50161746
((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for binding of PGD-2 in hTP binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319482
(CHEMBL1082939 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1cn(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C23H21N3O5S/c1-14-18(15(2)31-24-14)12-26-23(17-8-4-6-10-21(17)32(26,29)30)19-11-25(13-22(27)28)20-9-5-3-7-16(19)20/h3-11,23H,12-13H2,1-2H3,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162894
(CHEMBL361972 | [2-(4-Fluoro-benzenesulfonylamino)-...)Show SMILES OC(=O)CN1C2CCCCCC2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H23FN2O4S/c22-14-6-9-16(10-7-14)29(27,28)23-15-8-11-20-18(12-15)17-4-2-1-3-5-19(17)24(20)13-21(25)26/h6-12,17,19,23H,1-5,13H2,(H,25,26) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319495
(CHEMBL1082610 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(CCS1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C20H23N3O5S/c1-12-16(14(3)28-21-12)10-23-18(8-9-29(23,26)27)20-13(2)22(11-19(24)25)17-7-5-4-6-15(17)20/h4-7,18H,8-11H2,1-3H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319486
(CHEMBL1084893 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C24H23N3O5S/c1-14-19(16(3)32-25-14)12-27-24(18-9-5-7-11-21(18)33(27,30)31)23-15(2)26(13-22(28)29)20-10-6-4-8-17(20)23/h4-11,24H,12-13H2,1-3H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human prostaglandin D2 receptor assessed as inhibition of PGD2-induced receptor activation by cell based FLIPR assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319490
(CHEMBL1084903 | rac-{3-[1,1-Dioxo-2-(2-phenoxy-eth...)Show SMILES Cc1c(C2N(CCOc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H24N2O5S/c1-18-25(20-11-5-7-13-22(20)27(18)17-24(29)30)26-21-12-6-8-14-23(21)34(31,32)28(26)15-16-33-19-9-3-2-4-10-19/h2-14,26H,15-17H2,1H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162917
(CHEMBL360288 | [6-(4-Fluoro-benzenesulfonylamino)-...)Show SMILES OC(=O)Cn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C20H19FN2O4S/c21-13-5-8-15(9-6-13)28(26,27)22-14-7-10-19-17(11-14)16-3-1-2-4-18(16)23(19)12-20(24)25/h5-11,22H,1-4,12H2,(H,24,25) | PDB
Reactome pathway
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| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85401
(GT 2140)Show InChI InChI=1S/C14H24N4O/c15-13(8-11-4-2-1-3-5-11)14(19)17-7-6-12-9-16-10-18-12/h9-11,13H,1-8,15H2,(H,16,18)(H,17,19)/t13-/m0/s1 | KEGG
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| PC cid
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| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319491
(CHEMBL1083446 | rac-(3-{2-[2-(4-Chloro-phenoxy)-et...)Show SMILES Cc1c(C2N(CCOc3ccc(Cl)cc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H23ClN2O5S/c1-17-25(20-6-2-4-8-22(20)28(17)16-24(30)31)26-21-7-3-5-9-23(21)35(32,33)29(26)14-15-34-19-12-10-18(27)11-13-19/h2-13,26H,14-16H2,1H3,(H,30,31) | PDB
Reactome pathway
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| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319494
(CHEMBL1085069 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(C)(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C25H25N3O5S/c1-15-19(17(3)33-26-15)13-28-25(4,20-10-6-8-12-22(20)34(28,31)32)24-16(2)27(14-23(29)30)21-11-7-5-9-18(21)24/h5-12H,13-14H2,1-4H3,(H,29,30) | PDB
Reactome pathway
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| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162891
(CHEMBL179980 | [6-(4-Fluoro-benzenesulfonylamino)-...)Show SMILES OC(=O)Cn1c2CCC(Cc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12)c1ccccc1 Show InChI InChI=1S/C26H23FN2O4S/c27-19-7-10-21(11-8-19)34(32,33)28-20-9-13-25-23(15-20)22-14-18(17-4-2-1-3-5-17)6-12-24(22)29(25)16-26(30)31/h1-5,7-11,13,15,18,28H,6,12,14,16H2,(H,30,31) | PDB
Reactome pathway
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| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85406
(GT 2321)Show InChI InChI=1S/C15H26N2/c1(2-7-11-15-12-16-13-17-15)4-8-14-9-5-3-6-10-14/h12-14H,1-11H2,(H,16,17) | KEGG
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| 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85403
(GT 2130)Show InChI InChI=1S/C14H18N4O/c15-13(8-11-4-2-1-3-5-11)14(19)17-7-6-12-9-16-10-18-12/h1-5,9-10,13H,6-8,15H2,(H,16,18)(H,17,19)/t13-/m0/s1 | KEGG
UniProtKB/TrEMBL
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| 104 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162896
(CHEMBL369330 | [3-tert-Butyl-6-(4-fluoro-benzenesu...)Show SMILES CC(C)(C)C1CCc2c(C1)c1cc(NS(=O)(=O)c3ccc(F)cc3)ccc1n2CC(O)=O Show InChI InChI=1S/C24H27FN2O4S/c1-24(2,3)15-4-10-21-19(12-15)20-13-17(7-11-22(20)27(21)14-23(28)29)26-32(30,31)18-8-5-16(25)6-9-18/h5-9,11,13,15,26H,4,10,12,14H2,1-3H3,(H,28,29) | PDB
Reactome pathway
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| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162901
(CHEMBL180733 | [5-(4-Fluoro-benzenesulfonylamino)-...)Show SMILES OC(=O)Cn1c2CCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C19H17FN2O4S/c20-12-4-7-14(8-5-12)27(25,26)21-13-6-9-18-16(10-13)15-2-1-3-17(15)22(18)11-19(23)24/h4-10,21H,1-3,11H2,(H,23,24) | PDB
Reactome pathway
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| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319489
(CHEMBL1084902 | rac-[3-(1,1-Dioxo-2-phenethyl-2,3-...)Show SMILES Cc1c(C2N(CCc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H24N2O4S/c1-18-25(20-11-5-7-13-22(20)27(18)17-24(29)30)26-21-12-6-8-14-23(21)33(31,32)28(26)16-15-19-9-3-2-4-10-19/h2-14,26H,15-17H2,1H3,(H,29,30) | PDB
Reactome pathway
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| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162897
(3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26) | PDB
Reactome pathway
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| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound against CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162897
(3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26) | PDB
Reactome pathway
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| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50161746
((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1 | PDB
Reactome pathway
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PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50161746
((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1 | PDB
Reactome pathway
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| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50161746
((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1 | PDB
Reactome pathway
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| 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory concentration of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319477
(CHEMBL1086341 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...)Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2cc(F)ccc2n1CC(O)=O Show InChI InChI=1S/C18H15FN2O4S/c1-10-17(18-12-4-2-3-5-15(12)26(24,25)20-18)13-8-11(19)6-7-14(13)21(10)9-16(22)23/h2-8,18,20H,9H2,1H3,(H,22,23) | PDB
Reactome pathway
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| 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319485
(CHEMBL1085645 | rac-[3-(1,1-Dioxo-2-phenyl-2,3-dih...)Show SMILES Cc1c(C2N(c3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C24H20N2O4S/c1-16-23(18-11-5-7-13-20(18)25(16)15-22(27)28)24-19-12-6-8-14-21(19)31(29,30)26(24)17-9-3-2-4-10-17/h2-14,24H,15H2,1H3,(H,27,28) | PDB
Reactome pathway
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| 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319483
(CHEMBL1085640 | rac-{2-Methyl-3-[2-(3-methyl-butyl...)Show SMILES CC(C)CCN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C23H26N2O4S/c1-15(2)12-13-25-23(18-9-5-7-11-20(18)30(25,28)29)22-16(3)24(14-21(26)27)19-10-6-4-8-17(19)22/h4-11,15,23H,12-14H2,1-3H3,(H,26,27) | PDB
Reactome pathway
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| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85404
(GT 2146)Show InChI InChI=1S/C13H16N4O/c14-12(10-4-2-1-3-5-10)13(18)16-7-6-11-8-15-9-17-11/h1-5,8-9,12H,6-7,14H2,(H,15,17)(H,16,18)/t12-/m0/s1 | KEGG
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| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319481
(CHEMBL1085639 | rac-[3-(1,1-Dioxo-2-phenethyl-2,3-...)Show SMILES OC(=O)Cn1cc(C2N(CCc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C25H22N2O4S/c28-24(29)17-26-16-21(19-10-4-6-12-22(19)26)25-20-11-5-7-13-23(20)32(30,31)27(25)15-14-18-8-2-1-3-9-18/h1-13,16,25H,14-15,17H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319476
(CHEMBL1083158 | rac-[5-Chloro-3-(1,1-dioxo-2,3-dih...)Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2cc(Cl)ccc2n1CC(O)=O Show InChI InChI=1S/C18H15ClN2O4S/c1-10-17(18-12-4-2-3-5-15(12)26(24,25)20-18)13-8-11(19)6-7-14(13)21(10)9-16(22)23/h2-8,18,20H,9H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319484
(CHEMBL1085644 | rac-[3-(2-Isopropyl-1,1-dioxo-2,3-...)Show SMILES CC(C)N1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C21H22N2O4S/c1-13(2)23-21(16-9-5-7-11-18(16)28(23,26)27)20-14(3)22(12-19(24)25)17-10-6-4-8-15(17)20/h4-11,13,21H,12H2,1-3H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162925
(3-[6-(2-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccccc3F)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-17-6-2-4-8-20(17)29(27,28)23-14-9-10-19-16(13-14)15-5-1-3-7-18(15)24(19)12-11-21(25)26/h2,4,6,8-10,13,23H,1,3,5,7,11-12H2,(H,25,26) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Hrh3 protein
(RAT) | BDBM85408
(GT 2288)Show InChI InChI=1S/C14H20N2/c1-3-7-13(8-4-1)9-5-2-6-10-14-11-15-12-16-14/h11-13H,1-5,7-9H2,(H,15,16) | KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| PubMed
| 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gliatech Inc.
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 289: 1151-9 (1999)
BindingDB Entry DOI: 10.7270/Q2BZ64KX |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319480
(CHEMBL1086343 | rac-[3-(2-Benzyl-1,1-dioxo-2,3-dih...)Show SMILES OC(=O)Cn1cc(C2N(Cc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C24H20N2O4S/c27-23(28)16-25-15-20(18-10-4-6-12-21(18)25)24-19-11-5-7-13-22(19)31(29,30)26(24)14-17-8-2-1-3-9-17/h1-13,15,24H,14,16H2,(H,27,28) | PDB
Reactome pathway
KEGG
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162902
(3-(6-Benzenesulfonylamino-1,2,3,4-tetrahydro-carba...)Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C21H22N2O4S/c24-21(25)12-13-23-19-9-5-4-8-17(19)18-14-15(10-11-20(18)23)22-28(26,27)16-6-2-1-3-7-16/h1-3,6-7,10-11,14,22H,4-5,8-9,12-13H2,(H,24,25) | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50162892
(3-[6-(3-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...)Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3cccc(F)c3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-4-3-5-16(12-14)29(27,28)23-15-8-9-20-18(13-15)17-6-1-2-7-19(17)24(20)11-10-21(25)26/h3-5,8-9,12-13,23H,1-2,6-7,10-11H2,(H,25,26) | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes |
Bioorg Med Chem Lett 15: 1749-53 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.055
BindingDB Entry DOI: 10.7270/Q20P0ZHT |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319493
(CHEMBL1086537 | rac-{3-[2-(2-Hydroxy-ethyl)-1,1-di...)Show SMILES Cc1c(C2N(CCO)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C20H20N2O5S/c1-13-19(14-6-2-4-8-16(14)21(13)12-18(24)25)20-15-7-3-5-9-17(15)28(26,27)22(20)10-11-23/h2-9,20,23H,10-12H2,1H3,(H,24,25) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
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