Found 329 hits with Last Name = 'perrone' and Initial = 'mh' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080514
(3-[(R)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O Show InChI InChI=1S/C23H24N4O4S/c1-31-19-7-5-16-6-8-20(13-18(16)12-19)32(29,30)26-21-9-10-27(23(21)28)14-15-3-2-4-17(11-15)22(24)25/h2-8,11-13,21,26H,9-10,14H2,1H3,(H3,24,25)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.0470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | PDB
UniProtKB/SwissProt
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CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]prazosin from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226938
(CHEMBL38829)Show InChI InChI=1S/C12H15N3/c1-15-10-5-3-2-4-9(10)8-11(15)12-13-6-7-14-12/h2-5,11H,6-8H2,1H3,(H,13,14) | PDB
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| PubMed
| 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226949
(CHEMBL416072)Show InChI InChI=1S/C14H17N3/c1-2-9-17-12-6-4-3-5-11(12)10-13(17)14-15-7-8-16-14/h2-6,13H,1,7-10H2,(H,15,16) | PDB
UniProtKB/SwissProt
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| CHEMBL
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UniChem
| PubMed
| 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226962
(CHEMBL41224)Show InChI InChI=1S/C12H14ClN3/c1-16-10(12-14-5-6-15-12)7-8-3-2-4-9(13)11(8)16/h2-4,10H,5-7H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
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| 0.720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50019855
(2-(4,5-Dihydro-1H-imidazol-2-yl)-5-fluoro-1-methyl...)Show InChI InChI=1S/C12H14FN3/c1-16-10-3-2-9(13)6-8(10)7-11(16)12-14-4-5-15-12/h2-3,6,11H,4-5,7H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
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| 0.910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226939
(CHEMBL36616)Show InChI InChI=1S/C13H17N3/c1-2-16-11-6-4-3-5-10(11)9-12(16)13-14-7-8-15-13/h3-6,12H,2,7-9H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 0.910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226945
(CHEMBL38406)Show InChI InChI=1S/C13H17N3/c1-16-11-5-3-2-4-10(11)6-7-12(16)13-14-8-9-15-13/h2-5,12H,6-9H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
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| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50225285
(CHEBI:3757 | Catapres | Catapres-Tts-1 | Catapres-...)Show InChI InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14) | PDB
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| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226961
(CHEMBL38788)Show InChI InChI=1S/C14H19N3/c1-2-9-17-12-6-4-3-5-11(12)10-13(17)14-15-7-8-16-14/h3-6,13H,2,7-10H2,1H3,(H,15,16) | PDB
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| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226965
(CHEMBL39254)Show InChI InChI=1S/C12H14ClN3/c1-16-10-3-2-9(13)6-8(10)7-11(16)12-14-4-5-15-12/h2-3,6,11H,4-5,7H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
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| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226960
(CHEMBL41111)Show InChI InChI=1S/C11H13N3/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,10,14H,5-7H2,(H,12,13) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
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| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226937
(CHEMBL289153)Show InChI InChI=1S/C18H19N3/c1-2-6-14(7-3-1)13-21-16-9-5-4-8-15(16)12-17(21)18-19-10-11-20-18/h1-9,17H,10-13H2,(H,19,20) | PDB
UniProtKB/SwissProt
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| CHEMBL
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| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226943
(CHEMBL41171)Show InChI InChI=1S/C13H17N3/c1-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16(13)2/h3-6H,7-9H2,1-2H3,(H,14,15)/t13-/m0/s1 | PDB
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| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226947
(CHEMBL290853)Show InChI InChI=1S/C15H21N3/c1-2-3-10-18-13-7-5-4-6-12(13)11-14(18)15-16-8-9-17-15/h4-7,14H,2-3,8-11H2,1H3,(H,16,17) | PDB
UniProtKB/SwissProt
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| CHEMBL
PC cid
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| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226954
(CHEMBL38660)Show InChI InChI=1S/C11H15N3/c1-14(9-11-12-7-8-13-11)10-5-3-2-4-6-10/h2-6H,7-9H2,1H3,(H,12,13) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
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Similars
| PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226964
(CHEMBL41064)Show InChI InChI=1S/C17H17N3/c1-2-7-14(8-3-1)20-15-9-5-4-6-13(15)12-16(20)17-18-10-11-19-17/h1-9,16H,10-12H2,(H,18,19) | PDB
UniProtKB/SwissProt
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| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226940
(CHEMBL41456)Show InChI InChI=1S/C19H21N3/c1-2-6-15(7-3-1)10-13-22-17-9-5-4-8-16(17)14-18(22)19-20-11-12-21-19/h1-9,18H,10-14H2,(H,20,21) | PDB
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| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226932
(CHEMBL559829)Show InChI InChI=1S/C15H16N2/c1-11-13(10-15-16-8-9-17-15)7-6-12-4-2-3-5-14(11)12/h2-7H,8-10H2,1H3,(H,16,17) | PDB
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| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226949
(CHEMBL416072)Show InChI InChI=1S/C14H17N3/c1-2-9-17-12-6-4-3-5-11(12)10-13(17)14-15-7-8-16-14/h2-6,13H,1,7-10H2,(H,15,16) | PDB
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UniChem
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| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosin from rat brain cortical membranes; value rang... |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226924
(CHEMBL545647)Show InChI InChI=1S/C14H16N2/c1-10-12(9-14-15-6-7-16-14)8-11-4-2-3-5-13(10)11/h2-5H,6-9H2,1H3,(H,15,16) | PDB
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| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226942
(CHEMBL39286)Show SMILES [H][C@@]1(C)c2ccccc2N(C)[C@]1([H])C1=NCCN1 |t:15| Show InChI InChI=1S/C13H17N3/c1-9-10-5-3-4-6-11(10)16(2)12(9)13-14-7-8-15-13/h3-6,9,12H,7-8H2,1-2H3,(H,14,15)/t9-,12+/m1/s1 | PDB
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| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM13279
(4-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(C)[C@H]1CCN(Cc2csc(c2)C(N)=N)C1=O |r| Show InChI InChI=1S/C22H24N4O4S2/c1-25(19-7-8-26(22(19)27)12-14-9-20(21(23)24)31-13-14)32(28,29)18-6-4-15-3-5-17(30-2)10-16(15)11-18/h3-6,9-11,13,19H,7-8,12H2,1-2H3,(H3,23,24)/t19-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) | PDB
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TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) | PDB
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| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]-clonidine from alpha-1 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226938
(CHEMBL38829)Show InChI InChI=1S/C12H15N3/c1-15-10-5-3-2-4-9(10)8-11(15)12-13-6-7-14-12/h2-5,11H,6-8H2,1H3,(H,13,14) | PDB
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| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosin from rat brain cortical membranes; value rang... |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080482
(4-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2csc(c2)C(N)=N)C1=O Show InChI InChI=1S/C21H22N4O4S2/c1-29-16-4-2-14-3-5-17(10-15(14)9-16)31(27,28)24-18-6-7-25(21(18)26)11-13-8-19(20(22)23)30-12-13/h2-5,8-10,12,18,24H,6-7,11H2,1H3,(H3,22,23)/t18-/m0/s1 | PDB
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| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226956
(CHEMBL41861)Show InChI InChI=1S/C12H13Cl2N3/c1-17-10(12-15-2-3-16-12)5-7-4-8(13)6-9(14)11(7)17/h4,6,10H,2-3,5H2,1H3,(H,15,16) | PDB
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TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226929
(CHEMBL545646)Show InChI InChI=1S/C15H18N2/c1-11-13(10-15-16-8-9-17-15)7-6-12-4-2-3-5-14(11)12/h2-5H,6-10H2,1H3,(H,16,17) | PDB
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| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226929
(CHEMBL545646)Show InChI InChI=1S/C15H18N2/c1-11-13(10-15-16-8-9-17-15)7-6-12-4-2-3-5-14(11)12/h2-5H,6-10H2,1H3,(H,16,17) | PDB
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| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226944
(CHEMBL290324)Show InChI InChI=1S/C14H19N3S/c1-17-12-6-4-3-5-11(12)9-14(17,10-18-2)13-15-7-8-16-13/h3-6H,7-10H2,1-2H3,(H,15,16)/t14-/m1/s1 | PDB
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| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226955
(CHEMBL37352)Show InChI InChI=1S/C12H15N3/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12/h1-4,11,15H,5-8H2,(H,13,14) | PDB
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| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50019855
(2-(4,5-Dihydro-1H-imidazol-2-yl)-5-fluoro-1-methyl...)Show InChI InChI=1S/C12H14FN3/c1-16-10-3-2-9(13)6-8(10)7-11(16)12-14-4-5-15-12/h2-3,6,11H,4-5,7H2,1H3,(H,14,15) | PDB
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| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosin from rat brain cortical membranes; value rang... |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080498
(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiop...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(Cc1ccsc1)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O Show InChI InChI=1S/C28H28N4O4S2/c1-36-24-7-5-21-6-8-25(15-23(21)14-24)38(34,35)32(17-20-10-12-37-18-20)26-9-11-31(28(26)33)16-19-3-2-4-22(13-19)27(29)30/h2-8,10,12-15,18,26H,9,11,16-17H2,1H3,(H3,29,30)/t26-/m0/s1 | PDB
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| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080503
(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-(1H-p...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(Cc1ccn[nH]1)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O Show InChI InChI=1S/C27H28N6O4S/c1-37-23-7-5-19-6-8-24(15-21(19)14-23)38(35,36)33(17-22-9-11-30-31-22)25-10-12-32(27(25)34)16-18-3-2-4-20(13-18)26(28)29/h2-9,11,13-15,25H,10,12,16-17H2,1H3,(H3,28,29)(H,30,31)/t25-/m0/s1 | PDB
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| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM13282
(3-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(C)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O |r| Show InChI InChI=1S/C24H26N4O4S/c1-27(33(30,31)21-9-7-17-6-8-20(32-2)13-19(17)14-21)22-10-11-28(24(22)29)15-16-4-3-5-18(12-16)23(25)26/h3-9,12-14,22H,10-11,15H2,1-2H3,(H3,25,26)/t22-/m0/s1 | PDB
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| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50454831
(Napamezole)Show InChI InChI=1S/C14H16N2/c1-2-4-13-9-11(5-6-12(13)3-1)10-14-15-7-8-16-14/h1-4,9H,5-8,10H2,(H,15,16) | PDB
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| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50454831
(Napamezole)Show InChI InChI=1S/C14H16N2/c1-2-4-13-9-11(5-6-12(13)3-1)10-14-15-7-8-16-14/h1-4,9H,5-8,10H2,(H,15,16) | PDB
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| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226946
(CHEMBL288398)Show SMILES CC(C)N(C[C@]1(Cc2ccccc2N1C)C1=NCCN1)C(C)C |t:17| Show InChI InChI=1S/C19H30N4/c1-14(2)23(15(3)4)13-19(18-20-10-11-21-18)12-16-8-6-7-9-17(16)22(19)5/h6-9,14-15H,10-13H2,1-5H3,(H,20,21)/t19-/m1/s1 | PDB
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| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080475
(2-[[(S)-1-(3-Carbamimidoyl-benzyl)-2-oxo-pyrrolidi...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(CC(N)=O)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O Show InChI InChI=1S/C25H27N5O5S/c1-35-20-7-5-17-6-8-21(13-19(17)12-20)36(33,34)30(15-23(26)31)22-9-10-29(25(22)32)14-16-3-2-4-18(11-16)24(27)28/h2-8,11-13,22H,9-10,14-15H2,1H3,(H2,26,31)(H3,27,28)/t22-/m0/s1 | PDB
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| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226957
(CHEMBL43401)Show InChI InChI=1S/C15H21N3O/c1-2-19-10-9-18-13-6-4-3-5-12(13)11-14(18)15-16-7-8-17-15/h3-6,14H,2,7-11H2,1H3,(H,16,17) | PDB
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| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080500
(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-pyrid...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(Cc1ccccn1)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O Show InChI InChI=1S/C29H29N5O4S/c1-38-25-10-8-21-9-11-26(17-23(21)16-25)39(36,37)34(19-24-7-2-3-13-32-24)27-12-14-33(29(27)35)18-20-5-4-6-22(15-20)28(30)31/h2-11,13,15-17,27H,12,14,18-19H2,1H3,(H3,30,31)/t27-/m0/s1 | PDB
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| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226928
(CHEMBL553439)Show InChI InChI=1S/C15H18N2.ClH/c1-11(15-16-8-9-17-15)13-7-6-12-4-2-3-5-14(12)10-13;/h2-5,10-11H,6-9H2,1H3,(H,16,17);1H | PDB
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| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro |
J Med Chem 30: 1482-9 (1987)
BindingDB Entry DOI: 10.7270/Q2WS8WGP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080496
(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiop...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(Cc1cccs1)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O Show InChI InChI=1S/C28H28N4O4S2/c1-36-23-9-7-20-8-10-25(16-22(20)15-23)38(34,35)32(18-24-6-3-13-37-24)26-11-12-31(28(26)33)17-19-4-2-5-21(14-19)27(29)30/h2-10,13-16,26H,11-12,17-18H2,1H3,(H3,29,30)/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226958
(CHEMBL38579)Show InChI InChI=1S/C14H19N3O/c1-17-12-6-4-3-5-11(12)9-14(17,10-18-2)13-15-7-8-16-13/h3-6H,7-10H2,1-2H3,(H,15,16)/t14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080501
(3-{(S)-3-[Benzyl-(7-methoxy-naphthalene-2-sulfonyl...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(Cc1ccccc1)[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O Show InChI InChI=1S/C30H30N4O4S/c1-38-26-12-10-23-11-13-27(18-25(23)17-26)39(36,37)34(20-21-6-3-2-4-7-21)28-14-15-33(30(28)35)19-22-8-5-9-24(16-22)29(31)32/h2-13,16-18,28H,14-15,19-20H2,1H3,(H3,31,32)/t28-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50080510
(3-{(S)-3-[Ethyl-(7-methoxy-naphthalene-2-sulfonyl)...)Show SMILES CCN([C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O)S(=O)(=O)c1ccc2ccc(OC)cc2c1 Show InChI InChI=1S/C25H28N4O4S/c1-3-29(34(31,32)22-10-8-18-7-9-21(33-2)14-20(18)15-22)23-11-12-28(25(23)30)16-17-5-4-6-19(13-17)24(26)27/h4-10,13-15,23H,3,11-12,16H2,1-2H3,(H3,26,27)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226967
(CHEMBL41756)Show InChI InChI=1S/C13H15N3/c1-16-11(9-13-14-6-7-15-13)8-10-4-2-3-5-12(10)16/h2-5,8H,6-7,9H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes |
J Med Chem 30: 1555-62 (1987)
BindingDB Entry DOI: 10.7270/Q2NC63FN |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM13280
(3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-...)Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O |r| Show InChI InChI=1S/C23H24N4O4S/c1-31-19-7-5-16-6-8-20(13-18(16)12-19)32(29,30)26-21-9-10-27(23(21)28)14-15-3-2-4-17(11-15)22(24)25/h2-8,11-13,21,26H,9-10,14H2,1H3,(H3,24,25)/t21-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibition of human Coagulation factor Xa |
J Med Chem 42: 3557-71 (1999)
Article DOI: 10.1021/jm990040h
BindingDB Entry DOI: 10.7270/Q2M04640 |
More data for this
Ligand-Target Pair | |
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