Found 82 hits with Last Name = 'pertusati' and Initial = 'f' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bifunctional glutamate/proline--tRNA ligase
(Homo sapiens (Human)) | CHEMBL1163086
| PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
UniChem
| | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Proline--tRNA ligase
(Escherichia coli (strain K12)) | CHEMBL1163086
| KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Bifunctional glutamate/proline--tRNA ligase
(Homo sapiens (Human)) | CHEMBL5279127
| PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Adenosine kinase
(Homo sapiens (Human)) | CHEMBL5283680
| PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 232 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Glutamine--tRNA ligase
(Escherichia coli) | CHEMBL5291357
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Proline--tRNA ligase
(Escherichia coli (strain K12)) | CHEMBL5279127
| KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Hypoxanthine-guanine phosphoribosyltransferase
(Homo sapiens (Human)) | CHEMBL5283919
| PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | CHEMBL5282738
| PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cholesterol side-chain cleavage enzyme, mitochondrial
(Rattus norvegicus) | CHEMBL5289236
| Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Methionine--tRNA ligase
(Escherichia coli (strain K12)) | CHEMBL5287030
| PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Staphylococcus aureus (strain MRSA252)) | CHEMBL5265940
| KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Bacillus subtilis) | CHEMBL5272467
| KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Staphylococcus aureus (strain MRSA252)) | CHEMBL5277590
| KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50529668
(Enobosarm | Gtx-024 | MK-2866 | Ostarine | US10806...)Show SMILES C[C@](O)(COc1ccc(cc1)C#N)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50516763
(CHEMBL3185021)Show SMILES CC(O)(COc1ccc(cc1)C#N)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University
Curated by ChEMBL
| Assay Description
Antagonist activity at GAL4-DBD fused rat androgen receptor expressed in UAS-bla 293 cells assessed as reduction in R1881-induced activation incubate... |
Eur J Med Chem 180: 1-14 (2019)
Article DOI: 10.1016/j.ejmech.2019.07.001
BindingDB Entry DOI: 10.7270/Q2474F79 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Bacillus subtilis) | CHEMBL5271984
| KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535824
(CHEMBL4575144)Show SMILES CC(O)(COc1ccc(C#N)c(F)c1)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H13F4N3O5/c1-17(27,9-30-12-4-2-10(8-23)14(19)7-12)16(26)24-11-3-5-15(25(28)29)13(6-11)18(20,21)22/h2-7,27H,9H2,1H3,(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | CHEMBL5278937
| PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535836
(CHEMBL4558169)Show SMILES [H][C@@]12C[C@]1([H])[C@]1(C)C3CC[C@@]4(C)[C@@]([H])(CC[C@]4(OC(C)=O)C(C)=O)[C@]3([H])C=C(Cl)C1=CC2=O |r,c:33,t:29| Show InChI InChI=1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17?,18-,22-,23-,24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535830
(CHEMBL4523011)Show SMILES CC(O)(COc1ccc(cc1C(F)(F)F)C#N)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C19H13F6N3O5/c1-17(30,9-33-15-5-2-10(8-26)6-13(15)19(23,24)25)16(29)27-11-3-4-14(28(31)32)12(7-11)18(20,21)22/h2-7,30H,9H2,1H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535839
(CHEMBL4577418)Show SMILES CC1(C)N(C(=O)N(C1=O)c1ccc(cc1)C(F)(F)F)c1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C19H13F6N3O4/c1-17(2)15(29)26(11-5-3-10(4-6-11)18(20,21)22)16(30)27(17)12-7-8-14(28(31)32)13(9-12)19(23,24)25/h3-9H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535835
(CHEMBL4547536)Show SMILES CC1(C)N(C(=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C19H13F6N3O4/c1-17(2)15(29)26(11-5-3-4-10(8-11)18(20,21)22)16(30)27(17)14-7-6-12(28(31)32)9-13(14)19(23,24)25/h3-9H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535841
(CHEMBL4529395)Show SMILES CC1(C)N(C(=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O2/c1-17(2)15(28)26(13-7-3-5-11(9-13)18(20,21)22)16(29)27(17)14-8-4-6-12(10-14)19(23,24)25/h3-10H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Alpha-1-antichymotrypsin
(Homo sapiens) | CHEMBL5291453
| KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535837
(CHEMBL4482919)Show SMILES CC(O)(COc1ccccc1C(F)(F)F)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H14F6N2O5/c1-16(28,9-31-14-5-3-2-4-11(14)17(19,20)21)15(27)25-10-6-7-13(26(29)30)12(8-10)18(22,23)24/h2-8,28H,9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 183 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535829
(CHEMBL4529026)Show SMILES CC(O)(COc1ccccc1OC(F)(F)F)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H14F6N2O6/c1-16(28,9-31-13-4-2-3-5-14(13)32-18(22,23)24)15(27)25-10-6-7-12(26(29)30)11(8-10)17(19,20)21/h2-8,28H,9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 198 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535825
(CHEMBL4572299)Show SMILES OC(CSc1ccccc1C(F)(F)F)(C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O)C(F)(F)F Show InChI InChI=1S/C18H11F9N2O4S/c19-16(20,21)10-3-1-2-4-13(10)34-8-15(31,18(25,26)27)14(30)28-9-5-6-12(29(32)33)11(7-9)17(22,23)24/h1-7,31H,8H2,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 245 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535834
(CHEMBL4532289)Show SMILES CC1(C)N(C(=O)N(C1=O)c1ccc(cc1)C(F)(F)F)c1ccc(cc1C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C19H13F6N3O4/c1-17(2)15(29)26(11-5-3-10(4-6-11)18(20,21)22)16(30)27(17)14-8-7-12(28(31)32)9-13(14)19(23,24)25/h3-9H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 265 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535826
(CHEMBL4581453)Show SMILES CC(O)(CSc1ccccc1C(F)(F)F)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H14F6N2O4S/c1-16(28,9-31-14-5-3-2-4-11(14)17(19,20)21)15(27)25-10-6-7-13(26(29)30)12(8-10)18(22,23)24/h2-8,28H,9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | CHEMBL5281271
| PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | CHEMBL5276993
| PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | CHEMBL5275061
| PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | CHEMBL5288850
| PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | CHEMBL5267618
| PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535827
(CHEMBL4580745)Show SMILES CC(O)(CSc1ccccc1C(F)(F)F)C(=O)Nc1ccc(cc1C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H14F6N2O4S/c1-16(28,9-31-14-5-3-2-4-11(14)17(19,20)21)15(27)25-13-7-6-10(26(29)30)8-12(13)18(22,23)24/h2-8,28H,9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 332 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50425732
(ENZALUTAMIDE | US10053433, FC 4.129 | US10806720, ...)Show SMILES CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
UniChem
Similars
| DrugBank
Article
PubMed
| n/a | n/a | 361 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University
Curated by ChEMBL
| Assay Description
Antagonist activity at GAL4 DBD-fused androgen receptor LBD (unknown origin) transfected in UAS-bla GripTite 293 cells assessed as inhibition of R188... |
Bioorg Med Chem Lett 26: 3636-40 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.001
BindingDB Entry DOI: 10.7270/Q2571DX1 |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50425732
(ENZALUTAMIDE | US10053433, FC 4.129 | US10806720, ...)Show SMILES CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 361 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535840
(CHEMBL4533483)Show SMILES CC1(C)N(C(=O)N(C1=O)c1ccc(cc1)C(F)(F)F)c1ccc(cc1C(F)(F)F)C#N Show InChI InChI=1S/C20H13F6N3O2/c1-18(2)16(30)28(13-6-4-12(5-7-13)19(21,22)23)17(31)29(18)15-8-3-11(10-27)9-14(15)20(24,25)26/h3-9H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 402 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535843
(CHEMBL4589154)Show SMILES CC(O)(COc1cccc(OC(F)(F)F)c1)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H14F6N2O6/c1-16(28,9-31-11-3-2-4-12(8-11)32-18(22,23)24)15(27)25-10-5-6-14(26(29)30)13(7-10)17(19,20)21/h2-8,28H,9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 407 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535823
(CHEMBL4483683)Show SMILES CC(O)(CSc1ccccc1C(F)(F)F)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O2S/c1-17(29,10-30-15-5-3-2-4-13(15)18(20,21)22)16(28)27-12-7-6-11(9-26)14(8-12)19(23,24)25/h2-8,29H,10H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 425 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM18678
((2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...)Show SMILES C[C@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)/t17-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University
Curated by ChEMBL
| Assay Description
Antagonist activity at GAL4 DBD-fused androgen receptor LBD (unknown origin) transfected in UAS-bla GripTite 293 cells assessed as inhibition of R188... |
Bioorg Med Chem Lett 26: 3636-40 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.001
BindingDB Entry DOI: 10.7270/Q2571DX1 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM18678
((2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...)Show SMILES C[C@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM18525
(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)Show SMILES CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University
Curated by ChEMBL
| Assay Description
Antagonist activity at GAL4-DBD fused rat androgen receptor expressed in UAS-bla 293 cells assessed as reduction in R1881-induced activation incubate... |
Eur J Med Chem 180: 1-14 (2019)
Article DOI: 10.1016/j.ejmech.2019.07.001
BindingDB Entry DOI: 10.7270/Q2474F79 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50516764
(CHEMBL4473164)Show SMILES CC(O)(COc1cccc(c1)S(F)(F)(F)(F)F)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C17H14F8N2O5S/c1-16(29,9-32-11-3-2-4-12(8-11)33(21,22,23,24)25)15(28)26-10-5-6-14(27(30)31)13(7-10)17(18,19)20/h2-8,29H,9H2,1H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University
Curated by ChEMBL
| Assay Description
Antagonist activity at GAL4-DBD fused rat androgen receptor expressed in UAS-bla 293 cells assessed as reduction in R1881-induced activation incubate... |
Eur J Med Chem 180: 1-14 (2019)
Article DOI: 10.1016/j.ejmech.2019.07.001
BindingDB Entry DOI: 10.7270/Q2474F79 |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535828
(CHEMBL4519421)Show SMILES CC(O)(COc1ccc(OC(F)(F)F)cc1)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H14F6N2O6/c1-16(28,9-31-11-3-5-12(6-4-11)32-18(22,23)24)15(27)25-10-2-7-14(26(29)30)13(8-10)17(19,20)21/h2-8,28H,9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535842
(CHEMBL4572778)Show SMILES CC(O)(CSc1cccc(c1)C(F)(F)F)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H14F6N2O4S/c1-16(28,9-31-12-4-2-3-10(7-12)17(19,20)21)15(27)25-11-5-6-14(26(29)30)13(8-11)18(22,23)24/h2-8,28H,9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50189312
(CHEMBL3828139)Show SMILES CC(O)(CSc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C19H13F9N2O4S/c1-16(32,8-35-12-5-9(17(20,21)22)4-10(6-12)18(23,24)25)15(31)29-11-2-3-14(30(33)34)13(7-11)19(26,27)28/h2-7,32H,8H2,1H3,(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University
Curated by ChEMBL
| Assay Description
Antagonist activity at GAL4 DBD-fused androgen receptor LBD (unknown origin) transfected in UAS-bla GripTite 293 cells assessed as inhibition of R188... |
Bioorg Med Chem Lett 26: 3636-40 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.001
BindingDB Entry DOI: 10.7270/Q2571DX1 |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535831
(CHEMBL4516292)Show SMILES CC(O)(COc1ccc(cc1C(F)(F)F)C#N)C(=O)Nc1ccc(cc1C(F)(F)F)C#N Show InChI InChI=1S/C20H13F6N3O3/c1-18(31,10-32-16-5-3-12(9-28)7-14(16)20(24,25)26)17(30)29-15-4-2-11(8-27)6-13(15)19(21,22)23/h2-7,31H,10H2,1H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 736 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535832
(CHEMBL4585541)Show SMILES C[C@](O)(CS(=O)(=O)c1ccc(cc1)C(F)(F)F)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H14F6N2O4S/c1-17(29,10-32(30,31)14-6-3-12(4-7-14)18(20,21)22)16(28)27-13-5-2-11(9-26)15(8-13)19(23,24)25/h2-8,29H,10H2,1H3,(H,27,28)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 775 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Rattus norvegicus (Rat)) | BDBM50535833
(CHEMBL4521612)Show SMILES C[C@](O)(CS(=O)(=O)c1ccc(OC(F)(F)F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H14F6N2O5S/c1-17(29,10-33(30,31)14-6-4-13(5-7-14)32-19(23,24)25)16(28)27-12-3-2-11(9-26)15(8-12)18(20,21)22/h2-8,29H,10H2,1H3,(H,27,28)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 777 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy and Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ... |
Eur J Med Chem 118: 230-43 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N |
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Ligand-Target Pair | |
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