Compile Data Set for Download or QSAR

Found 702 hits with Last Name = 'petrone' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002630 (CHEMBL377174) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1ccc(C)cc1 |c:21| Show InChI InChI=1S/C25H30N2O3/c1-19-6-8-20(9-7-19)22-12-15-27(25(22)28)21-10-11-23(29-2)24(18-21)30-17-16-26-13-4-3-5-14-26/h6-12,18H,3-5,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476485 (CHEMBL234739) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(F)cc(c2C1=O)C(F)(F)F Show InChI InChI=1S/C24H26F4N2O3/c1-15-5-7-29(8-6-15)9-10-33-21-13-18(3-4-20(21)32-2)30-14-16-11-17(25)12-19(24(26,27)28)22(16)23(30)31/h3-4,11-13,15H,5-10,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002616 (CHEMBL213839) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1cccc(F)c1 |c:21| Show InChI InChI=1S/C24H27FN2O3/c1-29-22-9-8-20(17-23(22)30-15-14-26-11-3-2-4-12-26)27-13-10-21(24(27)28)18-6-5-7-19(25)16-18/h5-10,16-17H,2-4,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002642 (CHEMBL213987) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1ccc(Cl)c(Cl)c1 |c:21| Show InChI InChI=1S/C24H26Cl2N2O3/c1-30-22-8-6-18(16-23(22)31-14-13-27-10-3-2-4-11-27)28-12-9-19(24(28)29)17-5-7-20(25)21(26)15-17/h5-9,15-16H,2-4,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411716 (CHEMBL429132) Show SMILES Cc1ccc2c(cccc2n1)-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(C)(C)C)n1C Show InChI InChI=1S/C31H36N6OS/c1-20-10-11-23-24(8-6-9-25(23)32-20)28-34-35-30(36(28)5)39-17-7-14-37-15-12-21-18-26-27(19-22(21)13-16-37)38-29(33-26)31(2,3)4/h6,8-11,18-19H,7,12-17H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476478 (CHEMBL234109) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(Br)c2C1=O Show InChI InChI=1S/C23H27BrN2O3/c1-16-8-10-25(11-9-16)12-13-29-21-14-18(6-7-20(21)28-2)26-15-17-4-3-5-19(24)22(17)23(26)27/h3-7,14,16H,8-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411713 (CHEMBL255620) Show SMILES CN(C)c1nc2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc2o1 Show InChI InChI=1S/C29H33N7OS/c1-19-9-10-22-23(7-5-8-24(22)30-19)27-32-33-29(35(27)4)38-16-6-13-36-14-11-20-17-25-26(18-21(20)12-15-36)37-28(31-25)34(2)3/h5,7-10,17-18H,6,11-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476492 (CHEMBL234533) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2ccc(Cl)c(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-15-7-9-26(10-8-15)11-12-30-20-13-17(4-6-19(20)29-2)27-14-16-3-5-18(24)22(25)21(16)23(27)28/h3-6,13,15H,7-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476486 (CHEMBL395298) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(Cl)c(C)c(Cl)c2C1=O Show InChI InChI=1S/C24H28Cl2N2O3/c1-15-6-8-27(9-7-15)10-11-31-21-13-18(4-5-20(21)30-3)28-14-17-12-19(25)16(2)23(26)22(17)24(28)29/h4-5,12-13,15H,6-11,14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002678 (CHEMBL210053) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1ccc(Br)cc1 |c:21| Show InChI InChI=1S/C24H27BrN2O3/c1-29-22-10-9-20(17-23(22)30-16-15-26-12-3-2-4-13-26)27-14-11-21(24(27)28)18-5-7-19(25)8-6-18/h5-11,17H,2-4,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476481 (CHEMBL395059) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1C(C)c2cccc(Cl)c2C1=O Show InChI InChI=1S/C24H29ClN2O3/c1-16-9-11-26(12-10-16)13-14-30-22-15-18(7-8-21(22)29-3)27-17(2)19-5-4-6-20(25)23(19)24(27)28/h4-8,15-17H,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411678 (CHEMBL273199) Show SMILES Cc1cc(-c2ccc3CCN(CCCSc4nnc(-c5cccc6cnc(C)cc56)n4C)CCc3c2)n(C)n1 Show InChI InChI=1S/C31H35N7S/c1-21-17-28-26(20-32-21)7-5-8-27(28)30-33-34-31(36(30)3)39-16-6-13-38-14-11-23-9-10-25(19-24(23)12-15-38)29-18-22(2)35-37(29)4/h5,7-10,17-20H,6,11-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002663 (CHEMBL386332) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1CC=C(C1=O)c1ccc(C)cc1 |c:22| Show InChI InChI=1S/C26H32N2O3/c1-19-4-6-21(7-5-19)23-12-15-28(26(23)29)22-8-9-24(30-3)25(18-22)31-17-16-27-13-10-20(2)11-14-27/h4-9,12,18,20H,10-11,13-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476504 (CHEMBL388882) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2sc3ccccc3c2C1=O Show InChI InChI=1S/C25H28N2O3S/c1-17-9-11-26(12-10-17)13-14-30-21-15-18(7-8-20(21)29-2)27-16-23-24(25(27)28)19-5-3-4-6-22(19)31-23/h3-8,15,17H,9-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476467 (CHEMBL396747) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(Cl)c2C1=O Show InChI InChI=1S/C23H27ClN2O3/c1-16-8-10-25(11-9-16)12-13-29-21-14-18(6-7-20(21)28-2)26-15-17-4-3-5-19(24)22(17)23(26)27/h3-7,14,16H,8-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476462 (CHEMBL396748) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(c2C1=O)C(F)(F)F Show InChI InChI=1S/C24H27F3N2O3/c1-16-8-10-28(11-9-16)12-13-32-21-14-18(6-7-20(21)31-2)29-15-17-4-3-5-19(24(25,26)27)22(17)23(29)30/h3-7,14,16H,8-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476474 (CHEMBL234532) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-15-5-7-26(8-6-15)9-10-30-21-13-18(3-4-20(21)29-2)27-14-16-11-17(24)12-19(25)22(16)23(27)28/h3-4,11-13,15H,5-10,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476479 (CHEMBL234494) Show SMILES COc1ccc(cc1OCCN1CCC(C)(C)CC1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C24H28Cl2N2O3/c1-24(2)6-8-27(9-7-24)10-11-31-21-14-18(4-5-20(21)30-3)28-15-16-12-17(25)13-19(26)22(16)23(28)29/h4-5,12-14H,6-11,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476488 (CHEMBL234531) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c(Cl)cc(F)c2F Show InChI InChI=1S/C23H25ClF2N2O3/c1-14-5-7-27(8-6-14)9-10-31-20-11-15(3-4-19(20)30-2)28-13-16-21(23(28)29)17(24)12-18(25)22(16)26/h3-4,11-12,14H,5-10,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476480 (CHEMBL234006) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cccc(C)c2C1=O Show InChI InChI=1S/C24H30N2O3/c1-17-9-11-25(12-10-17)13-14-29-22-15-20(7-8-21(22)28-3)26-16-19-6-4-5-18(2)23(19)24(26)27/h4-8,15,17H,9-14,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476464 (CHEMBL395072) Show SMILES COc1ccc(cc1OCCN1CCCCCC1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-29-20-7-6-18(14-21(20)30-11-10-26-8-4-2-3-5-9-26)27-15-16-12-17(24)13-19(25)22(16)23(27)28/h6-7,12-14H,2-5,8-11,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002664 (CHEMBL212270) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CC=C(C1=O)c1cccc(Cl)c1 |c:21| Show InChI InChI=1S/C24H27ClN2O3/c1-29-22-9-8-20(17-23(22)30-15-14-26-11-3-2-4-12-26)27-13-10-21(24(27)28)18-6-5-7-19(25)16-18/h5-10,16-17H,2-4,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476463 (CHEMBL234492) Show SMILES COc1ccc(cc1OCCN1CCCC(C)C1)N1Cc2cc(Cl)cc(Cl)c2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-15-4-3-7-26(13-15)8-9-30-21-12-18(5-6-20(21)29-2)27-14-16-10-17(24)11-19(25)22(16)23(27)28/h5-6,10-12,15H,3-4,7-9,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476499 (CHEMBL232254) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c1cc(F)ccc1n2C Show InChI InChI=1S/C26H30FN3O3/c1-17-8-10-29(11-9-17)12-13-33-24-15-19(5-7-23(24)32-3)30-16-22-25(26(30)31)20-14-18(27)4-6-21(20)28(22)2/h4-7,14-15,17H,8-13,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476503 (CHEMBL395098) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c1cccc(F)c1n2C Show InChI InChI=1S/C26H30FN3O3/c1-17-9-11-29(12-10-17)13-14-33-23-15-18(7-8-22(23)32-3)30-16-21-24(26(30)31)19-5-4-6-20(27)25(19)28(21)2/h4-8,15,17H,9-14,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476473 (CHEMBL234738) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(Cl)c(Cl)c(C)c2C1=O Show InChI InChI=1S/C24H28Cl2N2O3/c1-15-6-8-27(9-7-15)10-11-31-21-13-18(4-5-20(21)30-3)28-14-17-12-19(25)23(26)16(2)22(17)24(28)29/h4-5,12-13,15H,6-11,14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476494 (CHEMBL234948) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1Cc2c(C1=O)c1cc(Cl)ccc1n2C Show InChI InChI=1S/C25H28ClN3O3/c1-27-20-8-6-17(26)14-19(20)24-21(27)16-29(25(24)30)18-7-9-22(31-2)23(15-18)32-13-12-28-10-4-3-5-11-28/h6-9,14-15H,3-5,10-13,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411672 (CHEMBL256477) Show SMILES CCc1nn(C)c2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc12 Show InChI InChI=1S/C30H35N7S/c1-5-26-25-18-21-12-15-37(16-13-22(21)19-28(25)36(4)34-26)14-7-17-38-30-33-32-29(35(30)3)24-8-6-9-27-23(24)11-10-20(2)31-27/h6,8-11,18-19H,5,7,12-17H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411669 (CHEMBL271631) Show SMILES CCc1nc2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc2s1 Show InChI InChI=1S/C29H32N6S2/c1-4-27-31-25-17-20-11-14-35(15-12-21(20)18-26(25)37-27)13-6-16-36-29-33-32-28(34(29)3)23-7-5-8-24-22(23)10-9-19(2)30-24/h5,7-10,17-18H,4,6,11-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411712 (CHEMBL271083) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(F)(F)C(F)(F)F)n1C Show InChI InChI=1S/C23H23F5N6O2S/c1-13-18(35-12-29-13)19-31-32-21(33(19)2)37-9-3-6-34-7-4-14-10-16-17(11-15(14)5-8-34)36-20(30-16)22(24,25)23(26,27)28/h10-12H,3-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411702 (CHEMBL256015) Show SMILES CC(C)c1nc2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc2o1 Show InChI InChI=1S/C30H34N6OS/c1-19(2)29-32-26-17-21-11-14-36(15-12-22(21)18-27(26)37-29)13-6-16-38-30-34-33-28(35(30)4)24-7-5-8-25-23(24)10-9-20(3)31-25/h5,7-10,17-19H,6,11-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476506 (CHEMBL232046) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c1cc(Cl)ccc1n2C Show InChI InChI=1S/C26H30ClN3O3/c1-17-8-10-29(11-9-17)12-13-33-24-15-19(5-7-23(24)32-3)30-16-22-25(26(30)31)20-14-18(27)4-6-21(20)28(22)2/h4-7,14-15,17H,8-13,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476490 (CHEMBL396527) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(C)cc(C)c2C1=O Show InChI InChI=1S/C25H32N2O3/c1-17-7-9-26(10-8-17)11-12-30-23-15-21(5-6-22(23)29-4)27-16-20-14-18(2)13-19(3)24(20)25(27)28/h5-6,13-15,17H,7-12,16H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002689 (CHEMBL209573) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1CC=C(C1=O)c1ccc(Cl)c(Cl)c1 |c:22| Show InChI InChI=1S/C25H28Cl2N2O3/c1-17-7-10-28(11-8-17)13-14-32-24-16-19(4-6-23(24)31-2)29-12-9-20(25(29)30)18-3-5-21(26)22(27)15-18/h3-6,9,15-17H,7-8,10-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002668 (CHEMBL215864) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1CC=C(C1=O)c1ccc(F)cc1 |c:22| Show InChI InChI=1S/C25H29FN2O3/c1-18-9-12-27(13-10-18)15-16-31-24-17-21(7-8-23(24)30-2)28-14-11-22(25(28)29)19-3-5-20(26)6-4-19/h3-8,11,17-18H,9-10,12-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476505 (CHEMBL233442) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1Cc2sc3ccccc3c2C1=O Show InChI InChI=1S/C24H26N2O3S/c1-28-19-10-9-17(15-20(19)29-14-13-25-11-5-2-6-12-25)26-16-22-23(24(26)27)18-7-3-4-8-21(18)30-22/h3-4,7-10,15H,2,5-6,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411668 (CHEMBL255567) Show SMILES CCc1nc2cc3CCN(CCCSc4nnc(-c5ocnc5C)n4C)CCc3cc2s1 Show InChI InChI=1S/C23H28N6OS2/c1-4-20-25-18-12-16-6-9-29(10-7-17(16)13-19(18)32-20)8-5-11-31-23-27-26-22(28(23)3)21-15(2)24-14-30-21/h12-14H,4-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411692 (CHEMBL401728) Show SMILES Cc1cc(-c2nc3cc4CCN(CCCSc5nnc(-c6ocnc6C)n5C)CCc4cc3o2)n(C)n1 Show InChI InChI=1S/C26H30N8O2S/c1-16-12-21(33(4)31-16)25-28-20-13-18-6-9-34(10-7-19(18)14-22(20)36-25)8-5-11-37-26-30-29-24(32(26)3)23-17(2)27-15-35-23/h12-15H,5-11H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50411703 (CHEMBL402826) Show SMILES CCCc1nc2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc2o1 Show InChI InChI=1S/C30H34N6OS/c1-4-7-28-32-26-18-21-12-15-36(16-13-22(21)19-27(26)37-28)14-6-17-38-30-34-33-29(35(30)3)24-8-5-9-25-23(24)11-10-20(2)31-25/h5,8-11,18-19H,4,6-7,12-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50370572 (CHEMBL85606 | SB-277011) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCc3cc(ccc3C2)C#N)CC1)c1ccnc2ccccc12 |r,wU:3.2,wD:6.6,(-5.17,2.38,;-5.16,.84,;-3.83,.08,;-2.49,.85,;-2.5,2.39,;-1.16,3.16,;.18,2.39,;1.51,3.16,;2.84,2.39,;4.18,3.16,;4.17,4.69,;5.51,5.46,;6.84,4.68,;8.18,5.44,;9.51,4.67,;9.5,3.12,;8.16,2.36,;6.83,3.14,;5.51,2.38,;10.85,5.43,;12.18,6.19,;.17,.85,;-1.15,.08,;-6.49,.07,;-7.83,.83,;-9.16,.06,;-9.16,-1.48,;-7.83,-2.25,;-7.83,-3.79,;-6.49,-4.56,;-5.15,-3.79,;-5.16,-2.25,;-6.49,-1.48,)| Show InChI InChI=1S/C28H30N4O/c29-18-21-5-8-23-19-32(16-13-22(23)17-21)15-12-20-6-9-24(10-7-20)31-28(33)26-11-14-30-27-4-2-1-3-25(26)27/h1-5,8,11,14,17,20,24H,6-7,9-10,12-13,15-16,19H2,(H,31,33)/t20-,24-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay				Bioorg Med Chem Lett 18: 901-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.066 BindingDB Entry DOI: 10.7270/Q2MK6F32
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476495 (CHEMBL232045) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2c(C1=O)c1ccc(Cl)cc1n2C Show InChI InChI=1S/C26H30ClN3O3/c1-17-8-10-29(11-9-17)12-13-33-24-15-19(5-7-23(24)32-3)30-16-22-25(26(30)31)20-6-4-18(27)14-21(20)28(22)2/h4-7,14-15,17H,8-13,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476489 (CHEMBL396505) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1Cc2cccc(Cl)c2C1=O Show InChI InChI=1S/C22H25ClN2O3/c1-27-19-9-8-17(14-20(19)28-13-12-24-10-3-2-4-11-24)25-15-16-6-5-7-18(23)21(16)22(25)26/h5-9,14H,2-4,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002632 (CHEMBL376962) Show SMILES COc1ccc(cc1OCCN1CCC(C)(C)CC1)N1CC=C(C1=O)c1ccc(Cl)c(Cl)c1 |c:23| Show InChI InChI=1S/C26H30Cl2N2O3/c1-26(2)9-12-29(13-10-26)14-15-33-24-17-19(5-7-23(24)32-3)30-11-8-20(25(30)31)18-4-6-21(27)22(28)16-18/h4-8,16-17H,9-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002685 (CHEMBL211850) Show SMILES COc1ccc(cc1OCCN1CCCC1)N1CC=C(C1=O)c1ccc(Cl)c(Cl)c1 |c:20| Show InChI InChI=1S/C23H24Cl2N2O3/c1-29-21-7-5-17(15-22(21)30-13-12-26-9-2-3-10-26)27-11-8-18(23(27)28)16-4-6-19(24)20(25)14-16/h4-8,14-15H,2-3,9-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002625 (CHEMBL209432) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1CC=C(C1=O)c1ccc(Br)cc1 |c:22| Show InChI InChI=1S/C25H29BrN2O3/c1-18-9-12-27(13-10-18)15-16-31-24-17-21(7-8-23(24)30-2)28-14-11-22(25(28)29)19-3-5-20(26)6-4-19/h3-8,11,17-18H,9-10,12-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476502 (CHEMBL397259) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1Cc2c(C1=O)c1ccc(Cl)cc1n2C Show InChI InChI=1S/C25H28ClN3O3/c1-27-20-14-17(26)6-8-19(20)24-21(27)16-29(25(24)30)18-7-9-22(31-2)23(15-18)32-13-12-28-10-4-3-5-11-28/h6-9,14-15H,3-5,10-13,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002646 (CHEMBL210007) Show SMILES COc1ccc(cc1OCCN1CCCCC1)C1=CCN(C1=O)c1ccc(Cl)c(Cl)c1 |t:19| Show InChI InChI=1S/C24H26Cl2N2O3/c1-30-22-8-5-17(15-23(22)31-14-13-27-10-3-2-4-11-27)19-9-12-28(24(19)29)18-6-7-20(25)21(26)16-18/h5-9,15-16H,2-4,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50002687 (CHEMBL214398) Show SMILES COc1ccc(cc1OCCN1CCCCC1)N1CCC(C)(C1=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H30Cl2N2O3/c1-25(18-6-8-20(26)21(27)16-18)10-13-29(24(25)30)19-7-9-22(31-2)23(17-19)32-15-14-28-11-4-3-5-12-28/h6-9,16-17H,3-5,10-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Psychiatry Centre of Excellence for Drug Discovery Curated by ChEMBL					Assay Description Binding affinity to human 5HT2C receptor				Bioorg Med Chem Lett 16: 3906-12 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.05.034 BindingDB Entry DOI: 10.7270/Q2FN17PF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476483 (CHEMBL395297) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1Cc2cc(Cl)c(Cl)cc2C1=O Show InChI InChI=1S/C23H26Cl2N2O3/c1-15-5-7-26(8-6-15)9-10-30-22-12-17(3-4-21(22)29-2)27-14-16-11-19(24)20(25)13-18(16)23(27)28/h3-4,11-13,15H,5-10,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 428-33 (2007) Article DOI: 10.1016/j.bmcl.2006.10.029 BindingDB Entry DOI: 10.7270/Q2TX3J4X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50476500 (CHEMBL233440) Show SMILES COc1ccc(cc1OCCN1CCC(C)CC1)N1C(O)c2c(C1=O)c1ccccc1n2C Show InChI InChI=1S/C26H31N3O4/c1-17-10-12-28(13-11-17)14-15-33-22-16-18(8-9-21(22)32-3)29-25(30)23-19-6-4-5-7-20(19)27(2)24(23)26(29)31/h4-9,16-17,26,31H,10-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 424-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.034 BindingDB Entry DOI: 10.7270/Q2Q52SC2
					More data for this Ligand-Target Pair

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