Compile Data Set for Download or QSAR

Found 29 hits with Last Name = 'placanica' and Initial = 'g'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM50133069 (3'-Ethylamino-[1,1';2',1'']terphenyl-4'-carbaldehy...) Show SMILES CCNc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C21H20N2O/c1-2-22-21-18(15-23-24)13-14-19(16-9-5-3-6-10-16)20(21)17-11-7-4-8-12-17/h3-14,22H,2,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50133070 (CHEMBL335465 | [1,1';2',1'']Terphenyl-4'-carbaldeh...) Show SMILES O=NCc1ccc(-c2ccccc2)c(c1)-c1ccccc1 Show InChI InChI=1S/C19H15NO/c21-20-14-15-11-12-18(16-7-3-1-4-8-16)19(13-15)17-9-5-2-6-10-17/h1-13H,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50133070 (CHEMBL335465 | [1,1';2',1'']Terphenyl-4'-carbaldeh...) Show SMILES O=NCc1ccc(-c2ccccc2)c(c1)-c1ccccc1 Show InChI InChI=1S/C19H15NO/c21-20-14-15-11-12-18(16-7-3-1-4-8-16)19(13-15)17-9-5-2-6-10-17/h1-13H,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50133069 (3'-Ethylamino-[1,1';2',1'']terphenyl-4'-carbaldehy...) Show SMILES CCNc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C21H20N2O/c1-2-22-21-18(15-23-24)13-14-19(16-9-5-3-6-10-16)20(21)17-11-7-4-8-12-17/h3-14,22H,2,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50133071 (3'-Hydroxy-[1,1';2',1'']terphenyl-4'-carbaldehyde ...) Show SMILES Oc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C19H15NO2/c21-19-16(13-20-22)11-12-17(14-7-3-1-4-8-14)18(19)15-9-5-2-6-10-15/h1-12,21H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50133071 (3'-Hydroxy-[1,1';2',1'']terphenyl-4'-carbaldehyde ...) Show SMILES Oc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C19H15NO2/c21-19-16(13-20-22)11-12-17(14-7-3-1-4-8-14)18(19)15-9-5-2-6-10-15/h1-12,21H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50133072 (3'-Amino-[1,1';2',1'']terphenyl-4'-carbaldehyde ox...) Show SMILES Nc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C19H16N2O/c20-19-16(13-21-22)11-12-17(14-7-3-1-4-8-14)18(19)15-9-5-2-6-10-15/h1-12H,13,20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50133072 (3'-Amino-[1,1';2',1'']terphenyl-4'-carbaldehyde ox...) Show SMILES Nc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C19H16N2O/c20-19-16(13-21-22)11-12-17(14-7-3-1-4-8-14)18(19)15-9-5-2-6-10-15/h1-12H,13,20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50133068 (3'-Methylamino-[1,1';2',1'']terphenyl-4'-carbaldeh...) Show SMILES CNc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C20H18N2O/c1-21-20-17(14-22-23)12-13-18(15-8-4-2-5-9-15)19(20)16-10-6-3-7-11-16/h2-13,21H,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50133068 (3'-Methylamino-[1,1';2',1'']terphenyl-4'-carbaldeh...) Show SMILES CNc1c(CN=O)ccc(-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C20H18N2O/c1-21-20-17(14-22-23)12-13-18(15-8-4-2-5-9-15)19(20)16-10-6-3-7-11-16/h2-13,21H,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity for human estrogen receptor alpha by displacement of [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50051832 (CHEMBL440280 | [((2E,6E,10E)-3,7,11,15-Tetramethyl...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#7]-[#6](=O)-[#6]P([#8])([#8])=O Show InChI InChI=1S/C22H38NO5P/c1-18(2)9-6-10-19(3)11-7-12-20(4)13-8-14-21(5)15-16-28-23-22(24)17-29(25,26)27/h9,11,13,15H,6-8,10,12,14,16-17H2,1-5H3,(H,23,24)(H2,25,26,27)/b19-11+,20-13+,21-15+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of Geranylgeranyl protein transferase I				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136457 (CHEMBL136472 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6](-[#6](=O)-[#7]-[#6]-[#6]=[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O |w:6.5| Show InChI InChI=1S/C23H40NO4P/c1-18(2)10-7-11-19(3)12-8-13-20(4)14-9-15-21(5)16-17-24-23(25)22(6)29(26,27)28/h10,12,14,16,22H,7-9,11,13,15,17H2,1-6H3,(H,24,25)(H2,26,27,28)/b19-12+,20-14+,21-16?	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of Geranylgeranyl protein transferase I				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136461 (CHEMBL139238 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6]-[#6](-[#6](=O)-[#7]-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O Show InChI InChI=1S/C24H42NO5P/c1-7-23(31(27,28)29)24(26)25-30-18-17-22(6)16-10-15-21(5)14-9-13-20(4)12-8-11-19(2)3/h11,13,15,17,23H,7-10,12,14,16,18H2,1-6H3,(H,25,26)(H2,27,28,29)/b20-13+,21-15+,22-17+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of Geranylgeranyl protein transferase I				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136459 (CHEMBL139377 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6](-[#6](=O)-[#7]-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O Show InChI InChI=1S/C23H40NO5P/c1-18(2)10-7-11-19(3)12-8-13-20(4)14-9-15-21(5)16-17-29-24-23(25)22(6)30(26,27)28/h10,12,14,16,22H,7-9,11,13,15,17H2,1-6H3,(H,24,25)(H2,26,27,28)/b19-12+,20-14+,21-16+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of Geranylgeranyl protein transferase I				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136460 (CHEMBL138033 | [((2E,6E,10E)-3,7,11,15-Tetramethyl...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#7]-[#6](=O)-[#6]P([#8])([#8])=O |w:18.18| Show InChI InChI=1S/C22H38NO4P/c1-18(2)9-6-10-19(3)11-7-12-20(4)13-8-14-21(5)15-16-23-22(24)17-28(25,26)27/h9,11,13,15H,6-8,10,12,14,16-17H2,1-5H3,(H,23,24)(H2,25,26,27)/b19-11+,20-13+,21-15?	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of Geranylgeranyl protein transferase I				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136458 (CHEMBL134682 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6]-[#6](-[#6](=O)-[#7]-[#6]-[#6]=[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O |w:7.6| Show InChI InChI=1S/C24H42NO4P/c1-7-23(30(27,28)29)24(26)25-18-17-22(6)16-10-15-21(5)14-9-13-20(4)12-8-11-19(2)3/h11,13,15,17,23H,7-10,12,14,16,18H2,1-6H3,(H,25,26)(H2,27,28,29)/b20-13+,21-15+,22-17?	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of Geranylgeranyl protein transferase I				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50051832 (CHEMBL440280 | [((2E,6E,10E)-3,7,11,15-Tetramethyl...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#7]-[#6](=O)-[#6]P([#8])([#8])=O Show InChI InChI=1S/C22H38NO5P/c1-18(2)9-6-10-19(3)11-7-12-20(4)13-8-14-21(5)15-16-28-23-22(24)17-29(25,26)27/h9,11,13,15H,6-8,10,12,14,16-17H2,1-5H3,(H,23,24)(H2,25,26,27)/b19-11+,20-13+,21-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl protein transferase				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136460 (CHEMBL138033 | [((2E,6E,10E)-3,7,11,15-Tetramethyl...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#7]-[#6](=O)-[#6]P([#8])([#8])=O |w:18.18| Show InChI InChI=1S/C22H38NO4P/c1-18(2)9-6-10-19(3)11-7-12-20(4)13-8-14-21(5)15-16-23-22(24)17-28(25,26)27/h9,11,13,15H,6-8,10,12,14,16-17H2,1-5H3,(H,23,24)(H2,25,26,27)/b19-11+,20-13+,21-15?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl protein transferase				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136461 (CHEMBL139238 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6]-[#6](-[#6](=O)-[#7]-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O Show InChI InChI=1S/C24H42NO5P/c1-7-23(31(27,28)29)24(26)25-30-18-17-22(6)16-10-15-21(5)14-9-13-20(4)12-8-11-19(2)3/h11,13,15,17,23H,7-10,12,14,16,18H2,1-6H3,(H,25,26)(H2,27,28,29)/b20-13+,21-15+,22-17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl protein transferase				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136458 (CHEMBL134682 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6]-[#6](-[#6](=O)-[#7]-[#6]-[#6]=[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O |w:7.6| Show InChI InChI=1S/C24H42NO4P/c1-7-23(30(27,28)29)24(26)25-18-17-22(6)16-10-15-21(5)14-9-13-20(4)12-8-11-19(2)3/h11,13,15,17,23H,7-10,12,14,16,18H2,1-6H3,(H,25,26)(H2,27,28,29)/b20-13+,21-15+,22-17?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl protein transferase				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136459 (CHEMBL139377 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6](-[#6](=O)-[#7]-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O Show InChI InChI=1S/C23H40NO5P/c1-18(2)10-7-11-19(3)12-8-13-20(4)14-9-15-21(5)16-17-29-24-23(25)22(6)30(26,27)28/h10,12,14,16,22H,7-9,11,13,15,17H2,1-6H3,(H,24,25)(H2,26,27,28)/b19-12+,20-14+,21-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl protein transferase				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50136457 (CHEMBL136472 | [1-((2E,6E,10E)-3,7,11,15-Tetrameth...) Show SMILES [#6]-[#6](-[#6](=O)-[#7]-[#6]-[#6]=[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])P([#8])([#8])=O |w:6.5| Show InChI InChI=1S/C23H40NO4P/c1-18(2)10-7-11-19(3)12-8-13-20(4)14-9-15-21(5)16-17-24-23(25)22(6)29(26,27)28/h10,12,14,16,22H,7-9,11,13,15,17H2,1-6H3,(H,24,25)(H2,26,27,28)/b19-12+,20-14+,21-16?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl protein transferase				Bioorg Med Chem Lett 13: 4405-8 (2003) BindingDB Entry DOI: 10.7270/Q2NG4Q10
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from human ERalpha				J Med Chem 49: 5001-12 (2006) Article DOI: 10.1021/jm060560u BindingDB Entry DOI: 10.7270/Q2ZG6RVQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from human ERbeta				J Med Chem 49: 5001-12 (2006) Article DOI: 10.1021/jm060560u BindingDB Entry DOI: 10.7270/Q2ZG6RVQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity for human estrogen receptor beta				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity for human estrogen receptor alpha				J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM50192460 (4-(4-hydroxyphenyl)-N-methyl-3-phenylanthranylaldo...) Show SMILES CNc1c(CN=O)ccc(-c2ccc(O)cc2)c1-c1ccccc1 Show InChI InChI=1S/C20H18N2O2/c1-21-20-16(13-22-24)9-12-18(14-7-10-17(23)11-8-14)19(20)15-5-3-2-4-6-15/h2-12,21,23H,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from human ERalpha				J Med Chem 49: 5001-12 (2006) Article DOI: 10.1021/jm060560u BindingDB Entry DOI: 10.7270/Q2ZG6RVQ
					More data for this Ligand-Target Pair