Compile Data Set for Download or QSAR

Found 18 hits with Last Name = 'rampillon' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280507 (6-Amino-2-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-benzo[d...) Show SMILES Nc1ccc2C(=O)N([C@H]3CN4CCC3CC4)C(=O)c3cccc1c23 |wD:8.7,(4.27,-3.19,;5.81,-3.2,;6.51,-1.84,;8.05,-1.76,;8.86,-3.03,;10.43,-2.92,;11.1,-1.55,;11.27,-4.23,;12.8,-4.15,;13.62,-5.45,;15.16,-5.37,;15.86,-3.99,;15.02,-2.7,;13.48,-2.77,;13.88,-4.27,;14.88,-3.8,;10.54,-5.63,;11.41,-6.91,;9,-5.71,;8.31,-7.06,;6.77,-7.14,;5.93,-5.85,;6.65,-4.46,;8.17,-4.41,)| Show InChI InChI=1S/C19H19N3O2/c20-15-5-4-14-17-12(15)2-1-3-13(17)18(23)22(19(14)24)16-10-21-8-6-11(16)7-9-21/h1-5,11,16H,6-10,20H2/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50056419 (4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1CN2CCC1CC2 |wD:13.13,TLB:12:13:17.16:19.20,(11.11,-14.18,;11.11,-12.63,;9.77,-11.88,;8.43,-12.66,;7.09,-11.89,;5.75,-12.66,;7.09,-10.33,;5.76,-9.57,;8.43,-9.56,;9.75,-10.36,;11.09,-9.59,;11.11,-8.04,;12.44,-10.36,;13.77,-9.59,;14.8,-8.58,;16.63,-8.19,;17.94,-9.45,;16.9,-10.39,;15.57,-9.1,;15.88,-7.77,;16.88,-7.14,)| Show InChI InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280498 (6-Amino-2-(1-aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]...) Show SMILES Nc1ccc2C(=O)N(C3CN4CCC3CC4)C(=O)c3cccc1c23 |(5.44,-5.69,;6.98,-5.6,;7.67,-4.24,;9.21,-4.16,;10.03,-5.43,;11.59,-5.32,;12.27,-3.95,;12.43,-6.63,;13.97,-6.55,;14.8,-7.85,;16.34,-7.77,;17.03,-6.39,;16.18,-5.1,;14.64,-5.17,;15.04,-6.66,;16.04,-6.2,;11.72,-8.02,;12.57,-9.31,;10.18,-8.11,;9.48,-9.46,;7.95,-9.54,;7.11,-8.25,;7.81,-6.86,;9.34,-6.8,)| Show InChI InChI=1S/C19H19N3O2/c20-15-5-4-14-17-12(15)2-1-3-13(17)18(23)22(19(14)24)16-10-21-8-6-11(16)7-9-21/h1-5,11,16H,6-10,20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280497 ((R)-2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]isoq...) Show SMILES O=C1N([C@H]2CN3CCC2CC3)C(=O)c2cccc3cccc1c23 |wD:3.2,(9.94,-6.84,;9.08,-5.56,;9.79,-4.16,;11.33,-4.09,;12.15,-5.37,;13.69,-5.3,;14.38,-3.93,;13.53,-2.64,;11.99,-2.71,;12.41,-4.2,;13.41,-3.73,;8.94,-2.87,;9.63,-1.49,;7.39,-2.96,;6.57,-1.7,;5.04,-1.78,;4.35,-3.15,;5.17,-4.41,;4.48,-5.79,;5.31,-7.08,;6.85,-7,;7.55,-5.65,;6.7,-4.34,)| Show InChI InChI=1S/C19H18N2O2/c22-18-14-5-1-3-13-4-2-6-15(17(13)14)19(23)21(18)16-11-20-9-7-12(16)8-10-20/h1-6,12,16H,7-11H2/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280499 ((S)-2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-2,3-dihydro-b...) Show SMILES O=C1N(Cc2cccc3cccc1c23)[C@@H]1CN2CCC1CC2 |wD:14.16,(9.78,-1.8,;8.99,-3.16,;9.76,-4.49,;8.99,-5.82,;7.44,-5.82,;6.67,-7.16,;5.13,-7.15,;4.36,-5.82,;5.13,-4.49,;4.36,-3.16,;5.13,-1.82,;6.67,-1.82,;7.44,-3.16,;6.67,-4.49,;11.3,-4.48,;11.3,-2.53,;12.98,-1.56,;14.66,-2.53,;14.66,-4.48,;12.98,-5.44,;13.65,-4.07,;13.65,-2.92,)| Show InChI InChI=1S/C19H20N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h1-6,13,17H,7-12H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280506 ((R)-2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-2,3-dihydro-b...) Show SMILES O=C1N(Cc2cccc3cccc1c23)[C@H]1CN2CCC1CC2 |wU:14.16,(9.78,-1.8,;8.99,-3.16,;9.76,-4.49,;8.99,-5.82,;7.44,-5.82,;6.67,-7.16,;5.13,-7.15,;4.36,-5.82,;5.13,-4.49,;4.36,-3.16,;5.13,-1.82,;6.67,-1.82,;7.44,-3.16,;6.67,-4.49,;11.3,-4.48,;11.3,-2.53,;12.98,-1.56,;14.66,-2.53,;14.66,-4.48,;12.98,-5.44,;13.65,-4.07,;13.65,-2.92,)| Show InChI InChI=1S/C19H20N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h1-6,13,17H,7-12H2/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50031475 (4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CN2CCC1CC2 |wU:13.13,TLB:12:13:17.16:19.20,(11.11,-14.18,;11.11,-12.63,;9.77,-11.88,;8.43,-12.66,;7.09,-11.89,;5.75,-12.66,;7.09,-10.33,;5.76,-9.57,;8.43,-9.56,;9.75,-10.36,;11.09,-9.59,;11.11,-8.04,;12.44,-10.36,;13.77,-9.59,;14.8,-8.58,;16.63,-8.19,;17.94,-9.45,;16.9,-10.39,;15.57,-9.1,;15.88,-7.77,;16.88,-7.14,)| Show InChI InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280497 ((R)-2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]isoq...) Show SMILES O=C1N([C@H]2CN3CCC2CC3)C(=O)c2cccc3cccc1c23 |wD:3.2,(9.94,-6.84,;9.08,-5.56,;9.79,-4.16,;11.33,-4.09,;12.15,-5.37,;13.69,-5.3,;14.38,-3.93,;13.53,-2.64,;11.99,-2.71,;12.41,-4.2,;13.41,-3.73,;8.94,-2.87,;9.63,-1.49,;7.39,-2.96,;6.57,-1.7,;5.04,-1.78,;4.35,-3.15,;5.17,-4.41,;4.48,-5.79,;5.31,-7.08,;6.85,-7,;7.55,-5.65,;6.7,-4.34,)| Show InChI InChI=1S/C19H18N2O2/c22-18-14-5-1-3-13-4-2-6-15(17(13)14)19(23)21(18)16-11-20-9-7-12(16)8-10-20/h1-6,12,16H,7-11H2/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280503 (2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-6-chloro-benzo[de...) Show SMILES Clc1ccc2C(=O)N(C3CN4CCC3CC4)C(=O)c3cccc1c23 |(4.64,-5.54,;6.18,-5.47,;6.87,-4.11,;8.4,-4.03,;9.22,-5.29,;10.78,-5.2,;11.46,-3.82,;11.62,-6.5,;13.16,-6.41,;13.99,-7.7,;15.52,-7.63,;16.22,-6.25,;15.36,-4.97,;13.83,-5.04,;14.24,-6.53,;15.23,-6.06,;10.91,-7.88,;11.76,-9.17,;9.38,-7.98,;8.66,-9.33,;7.13,-9.41,;6.3,-8.11,;7.01,-6.74,;8.53,-6.67,)| Show InChI InChI=1S/C19H17ClN2O2/c20-15-5-4-14-17-12(15)2-1-3-13(17)18(23)22(19(14)24)16-10-21-8-6-11(16)7-9-21/h1-5,11,16H,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280510 (2-(1-Methyl-piperidin-4-yl)-benzo[de]isoquinoline-...) Show SMILES CN1CCC(CC1)N1C(=O)c2cccc3cccc(C1=O)c23 Show InChI InChI=1S/C18H18N2O2/c1-19-10-8-13(9-11-19)20-17(21)14-6-2-4-12-5-3-7-15(16(12)14)18(20)22/h2-7,13H,8-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50161750 (CHEMBL290132 | N-(R)-1-Aza-bicyclo[2.2.2]oct-3-yl-...) Show SMILES COc1ccccc1C(=O)N[C@H]1CN2CCC1CC2 |wD:11.11,(-.72,-3.37,;.61,-4.13,;.63,-5.67,;-.7,-6.45,;-.7,-7.99,;.63,-8.76,;1.97,-7.99,;1.97,-6.44,;3.3,-5.67,;3.29,-4.13,;4.63,-6.42,;5.96,-5.65,;7.29,-6.42,;8.62,-5.65,;8.62,-4.11,;7.29,-3.34,;5.95,-4.11,;6.7,-5.44,;7.8,-4.35,)| Show InChI InChI=1S/C15H20N2O2/c1-19-14-5-3-2-4-12(14)15(18)16-13-10-17-8-6-11(13)7-9-17/h2-5,11,13H,6-10H2,1H3,(H,16,18)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280500 (6-Amino-2-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-benzo[d...) Show SMILES Nc1ccc2C(=O)N([C@@H]3CN4CCC3CC4)C(=O)c3cccc1c23 |wU:8.7,(4.27,-3.32,;5.81,-3.24,;6.5,-1.87,;8.04,-1.79,;8.86,-3.06,;10.42,-2.96,;11.1,-1.58,;11.26,-4.26,;12.79,-4.18,;13.62,-5.48,;15.16,-5.41,;15.86,-4.02,;15.01,-2.73,;13.47,-2.8,;13.87,-4.3,;14.88,-3.83,;10.54,-5.66,;11.4,-6.94,;9,-5.74,;8.3,-7.09,;6.77,-7.18,;5.93,-5.88,;6.64,-4.5,;8.16,-4.44,)| Show InChI InChI=1S/C19H19N3O2/c20-15-5-4-14-17-12(15)2-1-3-13(17)18(23)22(19(14)24)16-10-21-8-6-11(16)7-9-21/h1-5,11,16H,6-10,20H2/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280505 (3-(1-Aza-bicyclo[2.2.2]oct-3-yl)-6-chloro-1H-quina...) Show SMILES Clc1ccc2[nH]c(=O)n(C3CN4CCC3CC4)c(=O)c2c1 |(5.27,-4.99,;6.6,-5.75,;6.6,-7.3,;7.93,-8.07,;9.26,-7.3,;10.61,-8.06,;11.93,-7.3,;13.28,-8.06,;11.93,-5.75,;13.28,-4.97,;14.11,-6.27,;15.65,-6.19,;16.36,-4.82,;15.5,-3.53,;13.95,-3.61,;14.35,-5.08,;15.36,-4.6,;10.59,-4.97,;10.59,-3.44,;9.26,-5.75,;7.93,-4.99,)| Show InChI InChI=1S/C15H16ClN3O2/c16-10-1-2-12-11(7-10)14(20)19(15(21)17-12)13-8-18-5-3-9(13)4-6-18/h1-2,7,9,13H,3-6,8H2,(H,17,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280508 (2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-6-nitro-benzo[de]...) Show SMILES [O-][N+](=O)c1ccc2C(=O)N(C3CN4CCC3CC4)C(=O)c3cccc1c23 |(1.16,-2.48,;1.98,-3.77,;1.29,-5.13,;3.52,-3.7,;4.22,-2.33,;5.76,-2.26,;6.57,-3.51,;8.13,-3.42,;8.8,-2.04,;8.96,-4.71,;10.5,-4.64,;11.34,-5.93,;12.88,-5.85,;12.59,-4.28,;11.58,-4.75,;11.18,-3.26,;12.72,-3.19,;13.57,-4.48,;8.27,-6.11,;9.12,-7.38,;6.73,-6.18,;6.02,-7.54,;4.48,-7.63,;3.66,-6.32,;4.36,-4.94,;5.89,-4.89,)| Show InChI InChI=1S/C19H17N3O4/c23-18-13-3-1-2-12-15(22(25)26)5-4-14(17(12)13)19(24)21(18)16-10-20-8-6-11(16)7-9-20/h1-5,11,16H,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280501 (2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-6-bromo-benzo[de]...) Show SMILES Brc1ccc2C(=O)N(C3CN4CCC3CC4)C(=O)c3cccc1c23 |(4.93,-5.21,;6.47,-5.14,;7.18,-3.77,;8.7,-3.69,;9.52,-4.95,;11.09,-4.86,;11.76,-3.48,;11.92,-6.17,;13.47,-6.08,;14.31,-7.37,;15.84,-7.3,;16.54,-5.92,;15.67,-4.63,;14.15,-4.7,;14.55,-6.2,;15.56,-5.73,;11.23,-7.55,;12.09,-8.84,;9.69,-7.65,;8.98,-9,;7.44,-9.09,;6.61,-7.78,;7.32,-6.4,;8.84,-6.33,)| Show InChI InChI=1S/C19H17BrN2O2/c20-15-5-4-14-17-12(15)2-1-3-13(17)18(23)22(19(14)24)16-10-21-8-6-11(16)7-9-21/h1-5,11,16H,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280509 ((S)-2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]isoq...) Show SMILES O=C1N([C@@H]2CN3CCC2CC3)C(=O)c2cccc3cccc1c23 |wU:3.2,(2.36,-1.61,;1.51,-.33,;2.21,1.05,;3.75,1.14,;4.59,-.17,;6.13,-.08,;6.81,1.3,;5.97,2.58,;4.43,2.52,;4.83,1.02,;5.83,1.48,;1.38,2.36,;2.05,3.73,;-.18,2.26,;-.99,3.53,;-2.52,3.43,;-3.23,2.08,;-2.39,.82,;-3.1,-.56,;-2.26,-1.87,;-.73,-1.77,;-.02,-.42,;-.87,.89,)| Show InChI InChI=1S/C19H18N2O2/c22-18-14-5-1-3-13-4-2-6-15(17(13)14)19(23)21(18)16-11-20-9-7-12(16)8-10-20/h1-6,12,16H,7-11H2/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280504 (3-(1-Aza-bicyclo[2.2.2]oct-3-yl)-1H-quinazoline-2,...) Show SMILES O=c1[nH]c2ccccc2c(=O)n1C1CN2CCC1CC2 |(11.98,-8.01,;10.63,-7.23,;9.31,-8.01,;7.95,-7.25,;6.63,-8.02,;5.31,-7.25,;5.31,-5.7,;6.63,-4.93,;7.95,-5.7,;9.29,-4.92,;9.29,-3.38,;10.63,-5.69,;11.98,-4.92,;12.82,-6.22,;14.35,-6.14,;15.06,-4.76,;14.2,-3.47,;12.66,-3.54,;13.05,-5.02,;14.06,-4.55,)| Show InChI InChI=1S/C15H17N3O2/c19-14-11-3-1-2-4-12(11)16-15(20)18(14)13-9-17-7-5-10(13)6-8-17/h1-4,10,13H,5-9H2,(H,16,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50280502 (2-(8-Methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-benzo[de...) Show SMILES CN1C2CCC1CC(C2)N1C(=O)c2cccc3cccc(C1=O)c23 |THB:9:7:1:3.4| Show InChI InChI=1S/C20H20N2O2/c1-21-13-8-9-14(21)11-15(10-13)22-19(23)16-6-2-4-12-5-3-7-17(18(12)16)20(22)24/h2-7,13-15H,8-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	374	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)				Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814
					More data for this Ligand-Target Pair