Compile Data Set for Download or QSAR

Found 29 hits with Last Name = 'rasori' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50064858 ((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@H](Cc1ccncc1)c1ccccc1 |r| Show InChI InChI=1S/C25H27NO2/c1-27-24-12-11-21(18-25(24)28-22-9-5-6-10-22)23(20-7-3-2-4-8-20)17-19-13-15-26-16-14-19/h2-4,7-8,11-16,18,22-23H,5-6,9-10,17H2,1H3/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092632 (8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline ...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12 Show InChI InChI=1S/C21H15N3O2/c25-24(26)19-5-1-3-17(14-19)20-13-16(11-15-6-9-22-10-7-15)12-18-4-2-8-23-21(18)20/h1-10,12-14H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092630 (8-(3-Azido-phenyl)-6-pyridin-4-ylmethyl-quinoline ...) Show SMILES [N-]=[N+]=Nc1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12 Show InChI InChI=1S/C21H15N5/c22-26-25-19-5-1-3-17(14-19)20-13-16(11-15-6-9-23-10-7-15)12-18-4-2-8-24-21(18)20/h1-10,12-14H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092626 (8-(3-Azido-phenyl)-6-(4-iodo-imidazol-1-ylmethyl)-...) Show SMILES Ic1cn(Cc2cc(-c3cccc(c3)N=[N+]=[N-])c3ncccc3c2)cn1 Show InChI InChI=1S/C19H13IN6/c20-18-11-26(12-23-18)10-13-7-15-4-2-6-22-19(15)17(8-13)14-3-1-5-16(9-14)24-25-21/h1-9,11-12H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092623 (3-Benzyl-5-phenyl-3,5-dihydro-1,3,5,6-tetraaza-cyc...) Show SMILES O=c1n(-c2ccccc2)c2ncccc2c2ncn(Cc3ccccc3)c12 Show InChI InChI=1S/C22H16N4O/c27-22-20-19(24-15-25(20)14-16-8-3-1-4-9-16)18-12-7-13-23-21(18)26(22)17-10-5-2-6-11-17/h1-13,15H,14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092633 (8-(3-Azido-phenyl)-6-iodo-quinoline | CHEMBL127994) Show SMILES Ic1cc(-c2cccc(c2)N=[N+]=[N-])c2ncccc2c1 Show InChI InChI=1S/C15H9IN4/c16-12-7-11-4-2-6-18-15(11)14(9-12)10-3-1-5-13(8-10)19-20-17/h1-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092627 (8-(5-Azido-2-iodo-phenyl)-6-pyridin-4-ylmethyl-qui...) Show SMILES Ic1ccc(cc1-c1cc(Cc2ccncc2)cc2cccnc12)N=[N+]=[N-] Show InChI InChI=1S/C21H14IN5/c22-20-4-3-17(26-27-23)13-18(20)19-12-15(10-14-5-8-24-9-6-14)11-16-2-1-7-25-21(16)19/h1-9,11-13H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092624 (6-Imidazol-1-ylmethyl-8-phenyl-quinoline | CHEMBL4...) Show SMILES C(c1cc(-c2ccccc2)c2ncccc2c1)n1ccnc1 Show InChI InChI=1S/C19H15N3/c1-2-5-16(6-3-1)18-12-15(13-22-10-9-20-14-22)11-17-7-4-8-21-19(17)18/h1-12,14H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092629 (CHEMBL123576 | [8-(3-Iodo-phenyl)-quinolin-6-yl]-p...) Show SMILES Ic1cccc(c1)-c1cc(cc2cccnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C22H14INO/c23-19-10-4-8-16(13-19)20-14-18(12-17-9-5-11-24-21(17)20)22(25)15-6-2-1-3-7-15/h1-14H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074976 (2-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1ccc(o1)-c1ccccn1 Show InChI InChI=1S/C21H21NO3/c1-23-20-10-9-15(14-21(20)24-16-6-2-3-7-16)18-11-12-19(25-18)17-8-4-5-13-22-17/h4-5,8-14,16H,2-3,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092628 (6-Azido-8-(3-iodo-phenyl)-quinoline | CHEMBL124575) Show SMILES Ic1cccc(c1)-c1cc(cc2cccnc12)N=[N+]=[N-] Show InChI InChI=1S/C15H9IN4/c16-12-5-1-3-10(7-12)14-9-13(19-20-17)8-11-4-2-6-18-15(11)14/h1-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092631 (4-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-[3-iodo-5-...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CN(Cc2cc(I)cc(c2)C2(N=N2)C(F)(F)F)C(=O)C1 |c:29| Show InChI InChI=1S/C25H25F3IN3O3/c1-34-21-7-6-16(10-22(21)35-20-4-2-3-5-20)17-11-23(33)32(14-17)13-15-8-18(12-19(29)9-15)24(30-31-24)25(26,27)28/h6-10,12,17,20H,2-5,11,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074972 (2,5-Bis-(3-cyclopentyloxy-4-methoxy-phenyl)-furan ...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1ccc(o1)-c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C28H32O5/c1-29-25-13-11-19(17-27(25)31-21-7-3-4-8-21)23-15-16-24(33-23)20-12-14-26(30-2)28(18-20)32-22-9-5-6-10-22/h11-18,21-22H,3-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074965 (4-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1ccc(o1)-c1ccncc1 Show InChI InChI=1S/C21H21NO3/c1-23-20-7-6-16(14-21(20)24-17-4-2-3-5-17)19-9-8-18(25-19)15-10-12-22-13-11-15/h6-14,17H,2-5H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074974 (1-[2,5-Bis-(3,4-dimethoxy-phenyl)-furan-3-yl]-etha...) Show SMILES COc1ccc(cc1OC)-c1cc(C(C)=O)c(o1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H22O6/c1-13(23)16-12-19(14-6-8-17(24-2)20(10-14)26-4)28-22(16)15-7-9-18(25-3)21(11-15)27-5/h6-12H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074968 (2-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1ccc(o1)-c1ccc2ccccc2n1 Show InChI InChI=1S/C25H23NO3/c1-27-24-13-11-18(16-25(24)28-19-7-3-4-8-19)22-14-15-23(29-22)21-12-10-17-6-2-5-9-20(17)26-21/h2,5-6,9-16,19H,3-4,7-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092625 (3-[3-Iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)-b...) Show SMILES FC(F)(F)C1(N=N1)c1cc(I)cc(Cn2cnc3c2c(=O)n(-c2ccccc2)c2ncccc32)c1 |c:5| Show InChI InChI=1S/C24H14F3IN6O/c25-24(26,27)23(31-32-23)15-9-14(10-16(28)11-15)12-33-13-30-19-18-7-4-8-29-21(18)34(22(35)20(19)33)17-5-2-1-3-6-17/h1-11,13H,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074977 ((2,5-Diphenyl-furan-3-yl)-phenyl-methanone | CHEMB...) Show SMILES O=C(c1cc(oc1-c1ccccc1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H16O2/c24-22(18-12-6-2-7-13-18)20-16-21(17-10-4-1-5-11-17)25-23(20)19-14-8-3-9-15-19/h1-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074969 (3-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1ccc(o1)-c1cccnc1 Show InChI InChI=1S/C21H21NO3/c1-23-20-9-8-15(13-21(20)24-17-6-2-3-7-17)18-10-11-19(25-18)16-5-4-12-22-14-16/h4-5,8-14,17H,2-3,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074967 (2,5-Bis-(3,4-dimethoxy-phenyl)-furan | CHEMBL11093...) Show SMILES COc1ccc(cc1OC)-c1ccc(o1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C20H20O5/c1-21-17-7-5-13(11-19(17)23-3)15-9-10-16(25-15)14-6-8-18(22-2)20(12-14)24-4/h5-12H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074975 (CHEMBL325846 | [2-(3-Cyclopentyloxy-4-methoxy-phen...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1oc(cc1C(=O)c1ccccc1)-c1ccccn1 Show InChI InChI=1S/C28H25NO4/c1-31-24-15-14-20(17-26(24)32-21-11-5-6-12-21)28-22(27(30)19-9-3-2-4-10-19)18-25(33-28)23-13-7-8-16-29-23/h2-4,7-10,13-18,21H,5-6,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074973 (2-[3-Benzenesulfonyl-5-(3-cyclopentyloxy-4-methoxy...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1cc(c(o1)-c1ccccn1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H25NO5S/c1-31-23-15-14-19(17-25(23)32-20-9-5-6-10-20)24-18-26(27(33-24)22-13-7-8-16-28-22)34(29,30)21-11-3-2-4-12-21/h2-4,7-8,11-18,20H,5-6,9-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074970 (2-[4-Benzenesulfonyl-5-(3-cyclopentyloxy-4-methoxy...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1oc(cc1S(=O)(=O)c1ccccc1)-c1ccccn1 Show InChI InChI=1S/C27H25NO5S/c1-31-23-15-14-19(17-25(23)32-20-9-5-6-10-20)27-26(34(29,30)21-11-3-2-4-12-21)18-24(33-27)22-13-7-8-16-28-22/h2-4,7-8,11-18,20H,5-6,9-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074966 (4-(2,5-Diphenyl-furan-3-yl)-morpholine | CHEMBL323...) Show SMILES C1CN(CCO1)c1cc(oc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C20H19NO2/c1-3-7-16(8-4-1)19-15-18(21-11-13-22-14-12-21)20(23-19)17-9-5-2-6-10-17/h1-10,15H,11-14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50042058 ((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CNC(=O)C1 Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074971 (4-[(R)-2-(4-Cyclopentyloxy-3-methoxy-phenyl)-2-phe...) Show SMILES COc1cc(ccc1OC1CCCC1)[C@H](Cc1ccncc1)c1ccccc1 Show InChI InChI=1S/C25H27NO2/c1-27-25-18-21(11-12-24(25)28-22-9-5-6-10-22)23(20-7-3-2-4-8-20)17-19-13-15-26-16-14-19/h2-4,7-8,11-16,18,22-23H,5-6,9-10,17H2,1H3/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50064858 ((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@H](Cc1ccncc1)c1ccccc1 |r| Show InChI InChI=1S/C25H27NO2/c1-27-24-12-11-21(18-25(24)28-22-9-5-6-10-22)23(20-7-3-2-4-8-20)17-19-13-15-26-16-14-19/h2-4,7-8,11-16,18,22-23H,5-6,9-10,17H2,1H3/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074964 (2,5-diphenylfuran | CHEMBL109224 | PPF) Show SMILES c1cc(oc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C16H12O/c1-3-7-13(8-4-1)15-11-12-16(17-15)14-9-5-2-6-10-14/h1-12H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
					More data for this Ligand-Target Pair