Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50107460 ((S)-1-((R)-3-Phenyl-2-phenylmethanesulfonylamino-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Competitive kinetic for thrombin inhibition Ki was determined | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449917 (BMS-180560 | CHEMBL2021417) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50366780 (BMS-189090 | CHEMBL138877) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro reversible inhibition of thrombin catalytic activity | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449914 (CHEMBL2079784) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449919 (CHEMBL2021415) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50366331 (CHEMBL1790055) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449910 (CHEMBL2079782) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107463 ((S)-1-((R)-2-Methanesulfonylamino-3-phenyl-propion...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Competitive kinetic for human alpha thrombin inhibition Ki was determined | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449912 (CHEMBL2079781) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449909 (CHEMBL2079769) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449918 (BMS-181688 | CHEMBL2021416) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449920 (CHEMBL2079768) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449911 (CHEMBL2079770) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50282240 (CHEMBL288691 | Lithium; 2-[4-(2-butyl-5-hydroxymet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449915 (CHEMBL2021419) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50282248 (CHEMBL287065 | Lithium; 2-[5-(2-butyl-5-hydroxymet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50449916 (CHEMBL2021418) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50282244 (2-Butyl-3-{1-[2-(2H-tetrazol-5-yl)-phenyl]-1H-indo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor B (RAT) | BDBM50282254 (CHEMBL36259 | Potassium; 2-[6-(2-butyl-4-chloro-5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (RAT) | BDBM50449917 (BMS-180560 | CHEMBL2021417) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity for Angiotensin II receptor, type 2 determined | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50281226 (CHEMBL328736 | N-[(S)-1-[(2R,3S)-4-((R)-Butylsulfa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | 7.0 | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against human renal renin at pH 7 | Bioorg Med Chem Lett 3: 2739-2744 (1993) Article DOI: 10.1016/S0960-894X(01)80755-1 BindingDB Entry DOI: 10.7270/Q2Q52PJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50281231 ((S)-4-Methyl-2-[(S)-2-(2-methyl-propane-2-sulfonyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.0 | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against human renal renin at pH 7 | Bioorg Med Chem Lett 3: 2739-2744 (1993) Article DOI: 10.1016/S0960-894X(01)80755-1 BindingDB Entry DOI: 10.7270/Q2Q52PJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107460 ((S)-1-((R)-3-Phenyl-2-phenylmethanesulfonylamino-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of human alpha thrombin | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107460 ((S)-1-((R)-3-Phenyl-2-phenylmethanesulfonylamino-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of thrombin was determined | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107461 ((S)-1-((R)-3-Phenyl-2-phenylmethanesulfonylamino-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of human alpha thrombin | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50281229 (1H-Indole-2-carboxylic acid [(S)-1-[4-((S,S,R)-but...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.0 | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against human renal renin at pH 7 | Bioorg Med Chem Lett 3: 2739-2744 (1993) Article DOI: 10.1016/S0960-894X(01)80755-1 BindingDB Entry DOI: 10.7270/Q2Q52PJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107445 ((S)-4-((S)-2-{[((S)-1-Carbamimidoyl-piperidine-3-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107455 (4-Carbamimidoyl-N-{(S)-1-[(S)-3-hydroxy-2-(naphtha...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50366780 (BMS-189090 | CHEMBL138877) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50366780 (BMS-189090 | CHEMBL138877) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50228863 ((S)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of human alpha thrombin | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50228863 ((S)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of thrombin catalytic activity using s-2238 substrate at 10 uM was measured at rt after 3 min incubation with compound | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107446 (1-Carbamimidoyl-piperidine-3-carboxylic acid {(S)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50038001 ((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of human alpha thrombin | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50038001 ((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of thrombin catalytic activity using s-2238 substrate at 10 uM was measured at rat after 3 min incubation with compound | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107463 ((S)-1-((R)-2-Methanesulfonylamino-3-phenyl-propion...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of human alpha thrombin | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107442 (6-Guanidino-hexanoic acid {(S)-1-[(S)-3-hydroxy-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50281234 ((S)-N-[(S)-4-((R,R)-Butylsulfamoyl)-1-cyclohexylme...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 64 | n/a | n/a | n/a | n/a | 7.0 | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against human renal renin at pH 7 | Bioorg Med Chem Lett 3: 2739-2744 (1993) Article DOI: 10.1016/S0960-894X(01)80755-1 BindingDB Entry DOI: 10.7270/Q2Q52PJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107473 ((S)-1-((R)-2-Methanesulfonylamino-3-phenyl-propion...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of human alpha thrombin | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107434 (1-Carbamimidoyl-piperidine-3-carboxylic acid {(S)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107453 (5-Guanidino-pentanoic acid {(S)-1-[(S)-3-hydroxy-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107449 (1-Carbamimidoyl-piperidine-4-carboxylic acid {(S)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107447 (2-(1-Carbamimidoyl-piperidin-4-yl)-N-{(S)-1-[(S)-3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50281242 ((S)-N-[(S)-4-((R,R)-Butylsulfamoyl)-1-cyclohexylme...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 240 | n/a | n/a | n/a | n/a | 7.0 | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against human renal renin at pH 7 | Bioorg Med Chem Lett 3: 2739-2744 (1993) Article DOI: 10.1016/S0960-894X(01)80755-1 BindingDB Entry DOI: 10.7270/Q2Q52PJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107439 (1-Carbamimidoyl-piperidine-3-carboxylic acid {(S)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107444 (4-Guanidino-N-{(S)-1-[(S)-3-hydroxy-2-(naphthalene...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50451350 (CHEMBL2111938) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of thrombin catalytic activity using s-2238 substrate at 10 uM was measured at rat after 3 min incubation with compound | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107450 ((R)-1-Carbamimidoyl-piperidine-3-carboxylic acid {...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50064652 ((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against hydrolysis of human alpha thrombin | Bioorg Med Chem Lett 12: 45-9 (2001) BindingDB Entry DOI: 10.7270/Q2GX4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50107441 ((2S,4S)-1-[(S)-3-Hydroxy-2-(naphthalene-2-sulfonyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation. | Bioorg Med Chem Lett 12: 41-4 (2001) BindingDB Entry DOI: 10.7270/Q2MP53T0 | |||||||||||
More data for this Ligand-Target Pair |
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