Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM17636 (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 140 | -39.8 | n/a | n/a | n/a | n/a | n/a | 7.0 | 30 |
The University of Birmingham | Assay Description A fluorescence assay was used to determine the kinetic constants for the oxidation of 3alpha-androstanediol. The fluorescence emission of NADPH at 45... | Cancer Res 64: 1802-10 (2004) Article DOI: 10.1158/0008-5472.can-03-2847 BindingDB Entry DOI: 10.7270/Q2JS9NPR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 270 | -38.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 30 |
The University of Birmingham | Assay Description A fluorescence assay was used to determine the kinetic constants for the oxidation of 3alpha-androstanediol. The fluorescence emission of NADPH at 45... | Cancer Res 64: 1802-10 (2004) Article DOI: 10.1158/0008-5472.can-03-2847 BindingDB Entry DOI: 10.7270/Q2JS9NPR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.10E+3 | -33.0 | n/a | n/a | n/a | n/a | n/a | 7.0 | 30 |
The University of Birmingham | Assay Description Enzyme activity was measured in the reductive direction against varying concentrations of androsterone. Initial velocities were measured by observing... | Cancer Res 64: 1802-10 (2004) Article DOI: 10.1158/0008-5472.can-03-2847 BindingDB Entry DOI: 10.7270/Q2JS9NPR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM17636 (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 3.10E+3 | -32.0 | n/a | n/a | n/a | n/a | n/a | 7.0 | 30 |
The University of Birmingham | Assay Description Enzyme activity was measured in the reductive direction against varying concentrations of androsterone. Initial velocities were measured by observing... | Cancer Res 64: 1802-10 (2004) Article DOI: 10.1158/0008-5472.can-03-2847 BindingDB Entry DOI: 10.7270/Q2JS9NPR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50423645 (Albamycin | Cathomycin | NOVOBIOCIN) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM282 ((3R,4S,5R,6R)-5-hydroxy-6-[(2-hydroxy-3-{[4-hydrox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate... | Bioorg Med Chem 23: 2062-78 (2015) Article DOI: 10.1016/j.bmc.2015.03.004 BindingDB Entry DOI: 10.7270/Q2HT2R1V | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of 6-His-tagged Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 100 mins in presence of AT... | Bioorg Med Chem 22: 4924-34 (2014) Article DOI: 10.1016/j.bmc.2014.06.041 BindingDB Entry DOI: 10.7270/Q2J9685H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50423645 (Albamycin | Cathomycin | NOVOBIOCIN) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assay | Bioorg Med Chem 22: 6552-63 (2015) Article DOI: 10.1016/j.bmc.2014.10.016 BindingDB Entry DOI: 10.7270/Q2D50PJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50423645 (Albamycin | Cathomycin | NOVOBIOCIN) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) after 2 hrs | Eur J Med Chem 70: 143-53 (2013) Article DOI: 10.1016/j.ejmech.2013.09.025 BindingDB Entry DOI: 10.7270/Q2T72JWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50126842 (CHEMBL3628523) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066107 (CHEMBL3402951) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Secreted chorismate mutase (Mycobacterium tuberculosis H37Rv) | BDBM108084 (3-((5-nitrothiophen-2-yl)methylene)indolin-2-one (...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | 37 |
Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India | Assay Description The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ... | Chem Biol Drug Des 83: 498-506 (2014) Article DOI: 10.1111/cbdd.12265 BindingDB Entry DOI: 10.7270/Q2F76B65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50067153 (CHEMBL3403274) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate... | Bioorg Med Chem 23: 2062-78 (2015) Article DOI: 10.1016/j.bmc.2015.03.004 BindingDB Entry DOI: 10.7270/Q2HT2R1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50126797 (CHEMBL3628440) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50126828 (CHEMBL3628358) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Secreted chorismate mutase (Mycobacterium tuberculosis H37Rv) | BDBM22787 (1-acetyl-2,3-dihydro-1H-indole-2,3-dione | Acetyli...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | 37 |
Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India | Assay Description The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ... | Chem Biol Drug Des 83: 498-506 (2014) Article DOI: 10.1111/cbdd.12265 BindingDB Entry DOI: 10.7270/Q2F76B65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Secreted chorismate mutase (Mycobacterium tuberculosis H37Rv) | BDBM108083 (3-(4-nitrobenzylidene)indolin-2-one (Compound 24)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India | Assay Description The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ... | Chem Biol Drug Des 83: 498-506 (2014) Article DOI: 10.1111/cbdd.12265 BindingDB Entry DOI: 10.7270/Q2F76B65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Secreted chorismate mutase (Mycobacterium tuberculosis H37Rv) | BDBM50240433 (5-Isopropyl-2-methyl-phenol | CARVACROL | CHEMBL28...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Birla Institute of Technology & Science-Pilani | Assay Description Reaction volumes of 0.4 mL of chorismate (typically, 1 mM) in 50 mM Tris-HCl (pH 7.5), 0.5 mM EDTA, 0.1 mg/mL bovine serum albumin, and 10 mM β-... | J Enzyme Inhib Med Chem 29: 547-54 (2014) Article DOI: 10.3109/14756366.2013.823958 BindingDB Entry DOI: 10.7270/Q2MW2G15 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Secreted chorismate mutase (Mycobacterium tuberculosis H37Rv) | BDBM11022 (2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India | Assay Description The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ... | Chem Biol Drug Des 83: 498-506 (2014) Article DOI: 10.1111/cbdd.12265 BindingDB Entry DOI: 10.7270/Q2F76B65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50126391 (CHEMBL3628453) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50126177 (CHEMBL3628527) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066117 (CHEMBL3402957) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50037084 (CHEMBL3355797) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assay | Bioorg Med Chem 22: 6552-63 (2015) Article DOI: 10.1016/j.bmc.2014.10.016 BindingDB Entry DOI: 10.7270/Q2D50PJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066970 (CHEMBL3403255) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate... | Bioorg Med Chem 23: 2062-78 (2015) Article DOI: 10.1016/j.bmc.2015.03.004 BindingDB Entry DOI: 10.7270/Q2HT2R1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50037197 (CHEMBL3355806) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assay | Bioorg Med Chem 22: 6552-63 (2015) Article DOI: 10.1016/j.bmc.2014.10.016 BindingDB Entry DOI: 10.7270/Q2D50PJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066085 (CHEMBL3402933) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497758 (CHEMBL3309662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Secreted chorismate mutase (Mycobacterium tuberculosis H37Rv) | BDBM10304 (1-methyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL6...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India | Assay Description The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ... | Chem Biol Drug Des 83: 498-506 (2014) Article DOI: 10.1111/cbdd.12265 BindingDB Entry DOI: 10.7270/Q2F76B65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497761 (CHEMBL1487172) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50067151 (CHEMBL3403272) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate... | Bioorg Med Chem 23: 2062-78 (2015) Article DOI: 10.1016/j.bmc.2015.03.004 BindingDB Entry DOI: 10.7270/Q2HT2R1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50037202 (CHEMBL3355801) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assay | Bioorg Med Chem 22: 6552-63 (2015) Article DOI: 10.1016/j.bmc.2014.10.016 BindingDB Entry DOI: 10.7270/Q2D50PJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066096 (CHEMBL3402942) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50067154 (CHEMBL3403275) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate... | Bioorg Med Chem 23: 2062-78 (2015) Article DOI: 10.1016/j.bmc.2015.03.004 BindingDB Entry DOI: 10.7270/Q2HT2R1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497772 (CHEMBL1569394) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497750 (CHEMBL2098049 | GSK957094A | TCMDC-142444) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497767 (CHEMBL3310315) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50037194 (CHEMBL3355807) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assay | Bioorg Med Chem 22: 6552-63 (2015) Article DOI: 10.1016/j.bmc.2014.10.016 BindingDB Entry DOI: 10.7270/Q2D50PJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50126482 (CHEMBL3628449) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50037093 (CHEMBL3355788) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assay | Bioorg Med Chem 22: 6552-63 (2015) Article DOI: 10.1016/j.bmc.2014.10.016 BindingDB Entry DOI: 10.7270/Q2D50PJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50026388 (CHEMBL3331278) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science - Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli BL21 (DE3) using 2-trans-decenoyl substrate by spectrophotome... | Eur J Med Chem 86: 613-27 (2014) Article DOI: 10.1016/j.ejmech.2014.09.028 BindingDB Entry DOI: 10.7270/Q2SJ1N7N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50026396 (CHEMBL3331275) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science - Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli BL21 (DE3) using 2-trans-decenoyl substrate by spectrophotome... | Eur J Med Chem 86: 613-27 (2014) Article DOI: 10.1016/j.ejmech.2014.09.028 BindingDB Entry DOI: 10.7270/Q2SJ1N7N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066081 (CHEMBL3402930) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.14E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50100647 (CHEMBL3323168) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of 6-His-tagged Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 100 mins in presence of AT... | Bioorg Med Chem 22: 4924-34 (2014) Article DOI: 10.1016/j.bmc.2014.06.041 BindingDB Entry DOI: 10.7270/Q2J9685H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50126392 (CHEMBL3628452) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology&Science Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu... | Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497756 (CHEMBL3310302) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497759 (CHEMBL3309661) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066113 (CHEMBL3402954) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.57E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50067148 (CHEMBL3403269) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate... | Bioorg Med Chem 23: 2062-78 (2015) Article DOI: 10.1016/j.bmc.2015.03.004 BindingDB Entry DOI: 10.7270/Q2HT2R1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497775 (CHEMBL3207709) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair |
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