Compile Data Set for Download or QSAR

Found 151 hits with Last Name = 'rigolio' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Substance-K receptor (Rattus norvegicus (Rat))	BDBM50291261 ((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...) Show SMILES CN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H41Cl2N3O2/c1-27(41)38(2)35(29-13-7-4-8-14-29)19-23-39(24-20-35)21-9-17-34(30-15-16-31(36)32(37)25-30)18-10-22-40(26-34)33(42)28-11-5-3-6-12-28/h3-8,11-16,25H,9-10,17-24,26H2,1-2H3/t34-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Ability to displace [125I]NKA from Tachykinin receptor 2 in rat deodenum membrane				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051293 ((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...) Show SMILES CC[C@H](NC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H22N2O2/c1-2-20(17-11-5-3-6-12-17)27-25(29)22-19-15-9-10-16-21(19)26-23(24(22)28)18-13-7-4-8-14-18/h3-16,20,28H,2H2,1H3,(H,27,29)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding Affinity of [125I]-MePhe7-NKB towards Tachykinin receptor 3-CHO cell membranes(n=3-8)				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50291261 ((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...) Show SMILES CN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H41Cl2N3O2/c1-27(41)38(2)35(29-13-7-4-8-14-29)19-23-39(24-20-35)21-9-17-34(30-15-16-31(36)32(37)25-30)18-10-22-40(26-34)33(42)28-11-5-3-6-12-28/h3-8,11-16,25H,9-10,17-24,26H2,1-2H3/t34-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50291261 ((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...) Show SMILES CN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H41Cl2N3O2/c1-27(41)38(2)35(29-13-7-4-8-14-29)19-23-39(24-20-35)21-9-17-34(30-15-16-31(36)32(37)25-30)18-10-22-40(26-34)33(42)28-11-5-3-6-12-28/h3-8,11-16,25H,9-10,17-24,26H2,1-2H3/t34-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding Affinity of [125I]-MePhe7-NKB towards Tachykinin receptor 3-CHO cell membranes(n=3-8)				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074789 (3-Amino-2-phenyl-quinoline-4-carboxylic acid ((R)-...) Show SMILES CC[C@@H](NC(=O)c1c(N)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H23N3O/c1-2-20(17-11-5-3-6-12-17)28-25(29)22-19-15-9-10-16-21(19)27-24(23(22)26)18-13-7-4-8-14-18/h3-16,20H,2,26H2,1H3,(H,28,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074791 (3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid ((R...) Show SMILES CC[C@@H](NC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H22N2O2/c1-2-20(17-11-5-3-6-12-17)27-25(29)22-19-15-9-10-16-21(19)26-23(24(22)28)18-13-7-4-8-14-18/h3-16,20,28H,2H2,1H3,(H,27,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074785 (3-(2-Hydroxy-ethoxy)-2-phenyl-quinoline-4-carboxyl...) Show SMILES CC[C@@H](NC(=O)c1c(OCCO)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H26N2O3/c1-2-22(19-11-5-3-6-12-19)29-27(31)24-21-15-9-10-16-23(21)28-25(26(24)32-18-17-30)20-13-7-4-8-14-20/h3-16,22,30H,2,17-18H2,1H3,(H,29,31)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408857 (CHEMBL2113673) Show SMILES CC[C@H](NC(=O)c1c(OC)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H24N2O2/c1-3-21(18-12-6-4-7-13-18)28-26(29)23-20-16-10-11-17-22(20)27-24(25(23)30-2)19-14-8-5-9-15-19/h4-17,21H,3H2,1-2H3,(H,28,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408858 (CHEMBL2113680) Show SMILES CCOC(=O)COc1c(nc2ccccc2c1C(=O)N[C@@H](CC)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C29H28N2O4/c1-3-23(20-13-7-5-8-14-20)31-29(33)26-22-17-11-12-18-24(22)30-27(21-15-9-6-10-16-21)28(26)35-19-25(32)34-4-2/h5-18,23H,3-4,19H2,1-2H3,(H,31,33)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074781 (3-Dimethylaminomethyl-2-phenyl-quinoline-4-carboxy...) Show SMILES CC[C@@H](NC(=O)c1c(CN(C)C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H29N3O/c1-4-24(20-13-7-5-8-14-20)30-28(32)26-22-17-11-12-18-25(22)29-27(23(26)19-31(2)3)21-15-9-6-10-16-21/h5-18,24H,4,19H2,1-3H3,(H,30,32)/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074779 (CHEMBL10303 | [2-Phenyl-4-((R)-1-phenyl-propylcarb...) Show SMILES CC[C@@H](NC(=O)c1c(OCC(O)=O)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H24N2O4/c1-2-21(18-11-5-3-6-12-18)29-27(32)24-20-15-9-10-16-22(20)28-25(19-13-7-4-8-14-19)26(24)33-17-23(30)31/h3-16,21H,2,17H2,1H3,(H,29,32)(H,30,31)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074819 (3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid (1-...) Show SMILES CCC(NC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H22N2O2/c1-2-20(17-11-5-3-6-12-17)27-25(29)22-19-15-9-10-16-21(19)26-23(24(22)28)18-13-7-4-8-14-18/h3-16,20,28H,2H2,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074794 (3-Dimethylcarbamoylmethoxy-2-phenyl-quinoline-4-ca...) Show SMILES CC[C@@H](NC(=O)c1c(OCC(=O)N(C)C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N3O3/c1-4-23(20-13-7-5-8-14-20)31-29(34)26-22-17-11-12-18-24(22)30-27(21-15-9-6-10-16-21)28(26)35-19-25(33)32(2)3/h5-18,23H,4,19H2,1-3H3,(H,31,34)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051295 ((S)-3-methyl-2-phenyl-N-(1-phenylpropyl)quinoline-...) Show SMILES CC[C@H](NC(=O)c1c(C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H24N2O/c1-3-22(19-12-6-4-7-13-19)28-26(29)24-18(2)25(20-14-8-5-9-15-20)27-23-17-11-10-16-21(23)24/h4-17,22H,3H2,1-2H3,(H,28,29)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding Affinity of [125I]-MePhe7-NKB towards Tachykinin receptor 3-CHO cell membranes(n=3-8)				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408861 (CHEMBL2113679) Show SMILES CC[C@H](NC(=O)c1c(OCCN)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H27N3O2/c1-2-22(19-11-5-3-6-12-19)30-27(31)24-21-15-9-10-16-23(21)29-25(26(24)32-18-17-28)20-13-7-4-8-14-20/h3-16,22H,2,17-18,28H2,1H3,(H,30,31)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074776 (3-Ethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-...) Show SMILES CC[C@@H](NC(=O)c1c(CC)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H26N2O/c1-3-21-25(27(30)29-23(4-2)19-13-7-5-8-14-19)22-17-11-12-18-24(22)28-26(21)20-15-9-6-10-16-20/h5-18,23H,3-4H2,1-2H3,(H,29,30)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074782 (3-Methyl-2-phenyl-quinoline-4-carboxylic acid ((R)...) Show SMILES CC[C@@H](NC(=O)c1c(C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H24N2O/c1-3-22(19-12-6-4-7-13-19)28-26(29)24-18(2)25(20-14-8-5-9-15-20)27-23-17-11-10-16-21(23)24/h4-17,22H,3H2,1-2H3,(H,28,29)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408862 (CHEMBL2113678) Show SMILES CC[C@H](NC(=O)c1c(OCCN(C)C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H31N3O2/c1-4-24(21-13-7-5-8-14-21)31-29(33)26-23-17-11-12-18-25(23)30-27(22-15-9-6-10-16-22)28(26)34-20-19-32(2)3/h5-18,24H,4,19-20H2,1-3H3,(H,31,33)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074814 (3-Methoxy-2-phenyl-quinoline-4-carboxylic acid (1-...) Show SMILES CCC(NC(=O)c1c(OC)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H24N2O2/c1-3-21(18-12-6-4-7-13-18)28-26(29)23-20-16-10-11-17-22(20)27-24(25(23)30-2)19-14-8-5-9-15-19/h4-17,21H,3H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408865 (CHEMBL2113677) Show SMILES CC[C@H](NC(=O)c1c(OCC(N)=O)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H25N3O3/c1-2-21(18-11-5-3-6-12-18)30-27(32)24-20-15-9-10-16-22(20)29-25(19-13-7-4-8-14-19)26(24)33-17-23(28)31/h3-16,21H,2,17H2,1H3,(H2,28,31)(H,30,32)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408859 (CHEMBL2113681) Show SMILES CC[C@H](NC(=O)c1c(OCCN2CCCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H33N3O2/c1-2-26(23-13-5-3-6-14-23)33-31(35)28-25-17-9-10-18-27(25)32-29(24-15-7-4-8-16-24)30(28)36-22-21-34-19-11-12-20-34/h3-10,13-18,26H,2,11-12,19-22H2,1H3,(H,33,35)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074805 (3-Ethyl-2-phenyl-quinoline-4-carboxylic acid (1-ph...) Show SMILES CCC(NC(=O)c1c(CC)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H26N2O/c1-3-21-25(27(30)29-23(4-2)19-13-7-5-8-14-19)22-17-11-12-18-24(22)28-26(21)20-15-9-6-10-16-20/h5-18,23H,3-4H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408864 (CHEMBL2113676) Show SMILES CC[C@H](NC(=O)c1c(OCCCN(C)C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H33N3O2/c1-4-25(22-14-7-5-8-15-22)32-30(34)27-24-18-11-12-19-26(24)31-28(23-16-9-6-10-17-23)29(27)35-21-13-20-33(2)3/h5-12,14-19,25H,4,13,20-21H2,1-3H3,(H,32,34)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074810 (3-Methyl-2-phenyl-quinoline-4-carboxylic acid (1-p...) Show SMILES CCC(NC(=O)c1c(C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H24N2O/c1-3-22(19-12-6-4-7-13-19)28-26(29)24-18(2)25(20-14-8-5-9-15-20)27-23-17-11-10-16-21(23)24/h4-17,22H,3H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408863 (CHEMBL2113682) Show SMILES CC[C@H](NC(=O)c1c(NC(=O)CN(C)C)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O2/c1-4-23(20-13-7-5-8-14-20)31-29(35)26-22-17-11-12-18-24(22)30-27(21-15-9-6-10-16-21)28(26)32-25(34)19-33(2)3/h5-18,23H,4,19H2,1-3H3,(H,31,35)(H,32,34)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051289 ((R)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]...) Show SMILES COC(=O)[C@H](NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051292 ((S)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]...) Show SMILES COC(=O)[C@@H](NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding Affinity of [125I]-MePhe7-NKB towards Tachykinin receptor 3-CHO cell membranes(n=3-8)				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051289 ((R)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]...) Show SMILES COC(=O)[C@H](NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074773 (2-Phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl...) Show SMILES CC[C@@H](NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-2-22(18-11-5-3-6-12-18)27-25(28)21-17-24(19-13-7-4-8-14-19)26-23-16-10-9-15-20(21)23/h3-17,22H,2H2,1H3,(H,27,28)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074792 (2-Phenyl-3-propyl-quinoline-4-carboxylic acid (1-p...) Show SMILES CCCc1c(nc2ccccc2c1C(=O)NC(CC)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O/c1-3-13-23-26(28(31)30-24(4-2)20-14-7-5-8-15-20)22-18-11-12-19-25(22)29-27(23)21-16-9-6-10-17-21/h5-12,14-19,24H,3-4,13H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074802 (3-Butyl-2-phenyl-quinoline-4-carboxylic acid (1-ph...) Show SMILES CCCCc1c(nc2ccccc2c1C(=O)NC(CC)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C29H30N2O/c1-3-5-18-24-27(29(32)31-25(4-2)21-14-8-6-9-15-21)23-19-12-13-20-26(23)30-28(24)22-16-10-7-11-17-22/h6-17,19-20,25H,3-5,18H2,1-2H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408866 (CHEMBL2113683) Show SMILES CC[C@H](NC(=O)c1c(NC(C)=O)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H25N3O2/c1-3-22(19-12-6-4-7-13-19)30-27(32)24-21-16-10-11-17-23(21)29-25(26(24)28-18(2)31)20-14-8-5-9-15-20/h4-17,22H,3H2,1-2H3,(H,28,31)(H,30,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051294 (2-Phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl...) Show SMILES CC[C@H](NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-2-22(18-11-5-3-6-12-18)27-25(28)21-17-24(19-13-7-4-8-14-19)26-23-16-10-9-15-20(21)23/h3-17,22H,2H2,1H3,(H,27,28)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding Affinity of [125I]-MePhe7-NKB towards Tachykinin receptor 3-CHO cell membranes(n=3-8)				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50058261 (CHEMBL53765 | Phenyl-[(2-thiophen-3-yl-quinoline-4...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccsc1)c1ccccc1 Show InChI InChI=1S/C23H18N2O3S/c1-28-23(27)21(15-7-3-2-4-8-15)25-22(26)18-13-20(16-11-12-29-14-16)24-19-10-6-5-9-17(18)19/h2-14,21H,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074806 (2-Phenyl-quinoline-4-carboxylic acid (2-oxo-1-phen...) Show SMILES CC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O2/c1-17(28)24(19-12-6-3-7-13-19)27-25(29)21-16-23(18-10-4-2-5-11-18)26-22-15-9-8-14-20(21)22/h2-16,24H,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074815 (3-Chloro-2-phenyl-quinoline-4-carboxylic acid ((R)...) Show SMILES CC[C@@H](NC(=O)c1c(Cl)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H21ClN2O/c1-2-20(17-11-5-3-6-12-17)28-25(29)22-19-15-9-10-16-21(19)27-24(23(22)26)18-13-7-4-8-14-18/h3-16,20H,2H2,1H3,(H,28,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074809 (3-Fluoro-2-phenyl-quinoline-4-carboxylic acid ((R)...) Show SMILES CC[C@@H](NC(=O)c1c(F)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H21FN2O/c1-2-20(17-11-5-3-6-12-17)28-25(29)22-19-15-9-10-16-21(19)27-24(23(22)26)18-13-7-4-8-14-18/h3-16,20H,2H2,1H3,(H,28,29)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051291 (CHEMBL429951 | Phenyl-[(2-phenyl-quinoline-4-carbo...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051291 (CHEMBL429951 | Phenyl-[(2-phenyl-quinoline-4-carbo...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051291 (CHEMBL429951 | Phenyl-[(2-phenyl-quinoline-4-carbo...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding Affinity of [125I]-MePhe7-NKB towards Tachykinin receptor 3-CHO cell membranes(n=3-8)				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074775 (2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-pro...) Show SMILES CCC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-2-22(18-11-5-3-6-12-18)27-25(28)21-17-24(19-13-7-4-8-14-19)26-23-16-10-9-15-20(21)23/h3-17,22H,2H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50408860 (CHEMBL2113684) Show SMILES CC[C@H](NC(=O)c1c(Br)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H21BrN2O/c1-2-20(17-11-5-3-6-12-17)28-25(29)22-19-15-9-10-16-21(19)27-24(23(22)26)18-13-7-4-8-14-18/h3-16,20H,2H2,1H3,(H,28,29)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50291261 ((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...) Show SMILES CN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)c1ccccc1 |r| Show InChI InChI=1S/C35H41Cl2N3O2/c1-27(41)38(2)35(29-13-7-4-8-14-29)19-23-39(24-20-35)21-9-17-34(30-15-16-31(36)32(37)25-30)18-10-22-40(26-34)33(42)28-11-5-3-6-12-28/h3-8,11-16,25H,9-10,17-24,26H2,1-2H3/t34-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding Affinity of [125I]NKA towards Tachykinin receptor 2-CHO cell membranes (n=3-8)				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074788 (2,3-Diphenyl-quinoline-4-carboxylic acid (1-phenyl...) Show SMILES CCC(NC(=O)c1c(-c2ccccc2)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26N2O/c1-2-26(22-14-6-3-7-15-22)33-31(34)29-25-20-12-13-21-27(25)32-30(24-18-10-5-11-19-24)28(29)23-16-8-4-9-17-23/h3-21,26H,2H2,1H3,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074797 (2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-but...) Show SMILES CCCC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H24N2O/c1-2-11-23(19-12-5-3-6-13-19)28-26(29)22-18-25(20-14-7-4-8-15-20)27-24-17-10-9-16-21(22)24/h3-10,12-18,23H,2,11H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50058271 (CHEMBL416309 | Phenyl-{[2-(1H-pyrrol-2-yl)-quinoli...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccc[nH]1)c1ccccc1 Show InChI InChI=1S/C23H19N3O3/c1-29-23(28)21(15-8-3-2-4-9-15)26-22(27)17-14-20(19-12-7-13-24-19)25-18-11-6-5-10-16(17)18/h2-14,21,24H,1H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074824 (3-Hexyl-2-phenyl-quinoline-4-carboxylic acid (1-ph...) Show SMILES CCCCCCc1c(nc2ccccc2c1C(=O)NC(CC)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C31H34N2O/c1-3-5-6-13-21-26-29(31(34)33-27(4-2)23-16-9-7-10-17-23)25-20-14-15-22-28(25)32-30(26)24-18-11-8-12-19-24/h7-12,14-20,22,27H,3-6,13,21H2,1-2H3,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50058268 (CHEMBL297736 | [(7-Methoxy-2-phenyl-quinoline-4-ca...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2cc(OC)ccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H22N2O4/c1-31-19-13-14-20-21(16-22(27-23(20)15-19)17-9-5-3-6-10-17)25(29)28-24(26(30)32-2)18-11-7-4-8-12-18/h3-16,24H,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50058276 (CHEMBL301564 | Phenyl-[(2-thiophen-2-yl-quinoline-...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1cccs1)c1ccccc1 Show InChI InChI=1S/C23H18N2O3S/c1-28-23(27)21(15-8-3-2-4-9-15)25-22(26)17-14-19(20-12-7-13-29-20)24-18-11-6-5-10-16(17)18/h2-14,21H,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074780 (2-Phenyl-quinoline-4-carboxylic acid (2-methyl-1-p...) Show SMILES CC(C)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H24N2O/c1-18(2)25(20-13-7-4-8-14-20)28-26(29)22-17-24(19-11-5-3-6-12-19)27-23-16-10-9-15-21(22)23/h3-18,25H,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair

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