Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aromatase (Homo sapiens (Human)) | BDBM10044 ((2S,15S)-15-methyl-2-[(methylsulfanyl)methyl]tetra...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Aromatase inhibitor potency as iron-binding-related type II difference spectrum | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of human placental microsome cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Competitive inhibition of human placental Cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Aromatase inhibitor potency as iron-binding-related type II difference spectrum | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50368174 (CHEMBL1203762) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50368173 (CHEMBL1203766) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50008725 (4-(6,7,8,9-Tetrahydro-5H-imidazo[1,5-a]azepin-5-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50008726 (CHEMBL348913 | [4-(5,6,7,8-Tetrahydro-imidazo[1,5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50008733 (1-(4-Cyanobenzyl)-1H-imidazole | 4-((1H-imidazol-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50008729 (1-(4-Cyanobenzyl)-5-methyl-1H-imidazole | 4-(5-Met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50368172 (CHEMBL1203757) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50368175 (CHEMBL1203760) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50348420 (CHEMBL1800951) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CYP1A2 | ACS Med Chem Lett 1: 472-477 (2010) Article DOI: 10.1021/ml100138q BindingDB Entry DOI: 10.7270/Q2VX0GW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50348418 (CHEMBL1800931) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CYP1A2 | ACS Med Chem Lett 1: 472-477 (2010) Article DOI: 10.1021/ml100138q BindingDB Entry DOI: 10.7270/Q2VX0GW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50008724 (4-(5,6,7,8-Tetrahydro-imidazo[1,5-a]pyridin-5-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM50008730 (4-(5,6,7,8-Tetrahydro-imidazo[1,5-a]pyridin-5-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus) | BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of ACTH-stimulated aldosterone production in rat adrenal tissue | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of human placental microsome cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50348421 (CHEMBL1800953) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CYP1A2 | ACS Med Chem Lett 1: 472-477 (2010) Article DOI: 10.1021/ml100138q BindingDB Entry DOI: 10.7270/Q2VX0GW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50348422 (CHEMBL1800954) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CYP1A2 | ACS Med Chem Lett 1: 472-477 (2010) Article DOI: 10.1021/ml100138q BindingDB Entry DOI: 10.7270/Q2VX0GW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50348423 (CHEMBL1800955) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CYP1A2 | ACS Med Chem Lett 1: 472-477 (2010) Article DOI: 10.1021/ml100138q BindingDB Entry DOI: 10.7270/Q2VX0GW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50348424 (CHEMBL1800952) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CYP1A2 | ACS Med Chem Lett 1: 472-477 (2010) Article DOI: 10.1021/ml100138q BindingDB Entry DOI: 10.7270/Q2VX0GW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50348419 (CHEMBL1800933) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CYP1A2 | ACS Med Chem Lett 1: 472-477 (2010) Article DOI: 10.1021/ml100138q BindingDB Entry DOI: 10.7270/Q2VX0GW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28356 ((3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28356 ((3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0....) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28347 (3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.18E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28346 (1-[(9S)-6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pent...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.91E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aromatase (Homo sapiens (Human)) | BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of cytochrome P450 19A1 | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28341 ((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.19E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28341 ((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.54E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28346 (1-[(9S)-6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pent...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28357 (ZINC00347760, 26 | {3-[(10S)-2,9-dithiatricyclo[9....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.67E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28357 (ZINC00347760, 26 | {3-[(10S)-2,9-dithiatricyclo[9....) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28359 (1-benzyl-4-[(E)-[(1-cyclohexyl-2,4,6-trioxo-1,3-di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.52E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28349 (N-methyl-N-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.69E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28347 (3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.43E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28349 (N-methyl-N-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.63E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28358 ((2R,7S)-18-chloro-3,3-dimethyl-14-thia-3-azatetrac...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28358 ((2R,7S)-18-chloro-3,3-dimethyl-14-thia-3-azatetrac...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.53E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28345 (1-[2-(2-chloro-10H-phenothiazin-10-yl)-2-oxoethyl]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.87E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholesterol side-chain cleavage enzyme, mitochondrial (Homo sapiens (Human)) | BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of progesterone production in hamster ovarian tissue | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma cruzi) | BDBM28354 (2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.44E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28355 ((2S)-2-benzenesulfonamido-N-[2-(phenylsulfanyl)phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28359 (1-benzyl-4-[(E)-[(1-cyclohexyl-2,4,6-trioxo-1,3-di...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28360 (4-[(4S)-4-[(3-chlorophenyl)carbamoyl]-6-oxo-1,4,5,...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus) | BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of ACTH-stimulated corticosterone production in rat adrenal tissue | J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Trypanosoma brucei brucei) | BDBM28354 (2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-y...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta | Assay Description Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA... | J Med Chem 52: 1670-80 (2009) Article DOI: 10.1021/jm801306g BindingDB Entry DOI: 10.7270/Q2K35S0B | |||||||||||
More data for this Ligand-Target Pair |
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