Compile Data Set for Download or QSAR

Found 65 hits with Last Name = 'rogelj' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470540 (CHEMBL4282642) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C22H30N2O6/c1-5-14(4)17-19(30-21(17)27)20(26)23-11-16(25)24-18(13(2)3)22(28)29-12-15-9-7-6-8-10-15/h6-10,13-14,17-19H,5,11-12H2,1-4H3,(H,23,26)(H,24,25)/t14-,17-,18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470557 (CHEMBL4290778) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](COCc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C30H38N2O7/c1-5-20(4)24-26(39-30(24)36)28(34)32-25(19(2)3)27(33)31-23(18-37-16-21-12-8-6-9-13-21)29(35)38-17-22-14-10-7-11-15-22/h6-15,19-20,23-26H,5,16-18H2,1-4H3,(H,31,33)(H,32,34)/t20-,23-,24-,25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470536 (CHEMBL4292798) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H37N3O5/c1-7-16(6)18-21(33-25(18)32)24(31)28-20(15(4)5)23(30)27-19(14(2)3)22(29)26-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,30)(H,28,31)/t16-,18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470555 (CHEMBL4293394) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C26H38N2O6/c1-7-17(6)20-22(34-25(20)31)24(30)27-19(13-15(2)3)23(29)28-21(16(4)5)26(32)33-14-18-11-9-8-10-12-18/h8-12,15-17,19-22H,7,13-14H2,1-6H3,(H,27,30)(H,28,29)/t17-,19-,20-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470553 (CHEMBL4282369) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C29H36N2O6/c1-5-19(4)23-25(37-29(23)35)27(33)31-24(18(2)3)26(32)30-22(16-20-12-8-6-9-13-20)28(34)36-17-21-14-10-7-11-15-21/h6-15,18-19,22-25H,5,16-17H2,1-4H3,(H,30,32)(H,31,33)/t19-,22-,23-,24-,25+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470547 (CHEMBL4287467) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCCC=C |r| Show InChI InChI=1S/C22H36N2O6/c1-8-10-11-29-22(28)17(13(5)6)24-19(25)16(12(3)4)23-20(26)18-15(14(7)9-2)21(27)30-18/h8,12-18H,1,9-11H2,2-7H3,(H,23,26)(H,24,25)/t14-,15-,16-,17-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470539 (CHEMBL4293877) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C25H36N2O6/c1-7-16(6)18-21(33-24(18)30)23(29)26-19(14(2)3)22(28)27-20(15(4)5)25(31)32-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,28)/t16-,18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470549 (CHEMBL4286462) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1OC(=O)[C@H]1C1CC1)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H32N2O6/c1-13(2)18(25-22(28)20-17(16-10-11-16)23(29)32-20)21(27)26-19(14(3)4)24(30)31-12-15-8-6-5-7-9-15/h5-9,13-14,16-20H,10-12H2,1-4H3,(H,25,28)(H,26,27)/t17-,18-,19-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470561 (CHEMBL4292698) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C26H38N2O6/c1-7-17(6)20-22(34-26(20)32)24(30)28-21(16(4)5)23(29)27-19(13-15(2)3)25(31)33-14-18-11-9-8-10-12-18/h8-12,15-17,19-22H,7,13-14H2,1-6H3,(H,27,29)(H,28,30)/t17-,19-,20-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470556 (CHEMBL4282576) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C30H38N2O7/c1-5-20(4)24-26(39-29(24)35)28(34)31-23(18-37-16-21-12-8-6-9-13-21)27(33)32-25(19(2)3)30(36)38-17-22-14-10-7-11-15-22/h6-15,19-20,23-26H,5,16-18H2,1-4H3,(H,31,34)(H,32,33)/t20-,23-,24-,25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470552 (CHEMBL4281941) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C29H36N2O6/c1-5-19(4)23-25(37-28(23)34)27(33)30-22(16-20-12-8-6-9-13-20)26(32)31-24(18(2)3)29(35)36-17-21-14-10-7-11-15-21/h6-15,18-19,22-25H,5,16-17H2,1-4H3,(H,30,33)(H,31,32)/t19-,22-,23-,24-,25+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470537 (CHEMBL4278729) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H35ClN2O6/c1-7-15(6)18-21(34-24(18)31)23(30)27-19(13(2)3)22(29)28-20(14(4)5)25(32)33-12-16-8-10-17(26)11-9-16/h8-11,13-15,18-21H,7,12H2,1-6H3,(H,27,30)(H,28,29)/t15-,18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470546 (CHEMBL4282198) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCC(C)C |r| Show InChI InChI=1S/C22H38N2O6/c1-9-14(8)15-18(30-21(15)27)20(26)23-16(12(4)5)19(25)24-17(13(6)7)22(28)29-10-11(2)3/h11-18H,9-10H2,1-8H3,(H,23,26)(H,24,25)/t14-,15-,16-,17-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50470557 (CHEMBL4290778) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](COCc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C30H38N2O7/c1-5-20(4)24-26(39-30(24)36)28(34)32-25(19(2)3)27(33)31-23(18-37-16-21-12-8-6-9-13-21)29(35)38-17-22-14-10-7-11-15-22/h6-15,19-20,23-26H,5,16-18H2,1-4H3,(H,31,33)(H,32,34)/t20-,23-,24-,25-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470559 (CHEMBL4285979) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCC=C |r| Show InChI InChI=1S/C21H34N2O6/c1-8-10-28-21(27)16(12(5)6)23-18(24)15(11(3)4)22-19(25)17-14(13(7)9-2)20(26)29-17/h8,11-17H,1,9-10H2,2-7H3,(H,22,25)(H,23,24)/t13-,14-,15-,16-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50277889 (CARFILZOMIB | CHEMBL451887) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470558 (CHEMBL4283227) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(=O)OCc1ccccc1)C(C)(C)C |r| Show InChI InChI=1S/C26H38N2O6/c1-8-16(4)18-20(34-24(18)31)23(30)27-19(15(2)3)22(29)28-21(26(5,6)7)25(32)33-14-17-12-10-9-11-13-17/h9-13,15-16,18-21H,8,14H2,1-7H3,(H,27,30)(H,28,29)/t16-,18-,19-,20+,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470560 (CHEMBL4276815) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccc(OC)cc1 |r| Show InChI InChI=1S/C26H38N2O7/c1-8-16(6)19-22(35-25(19)31)24(30)27-20(14(2)3)23(29)28-21(15(4)5)26(32)34-13-17-9-11-18(33-7)12-10-17/h9-12,14-16,19-22H,8,13H2,1-7H3,(H,27,30)(H,28,29)/t16-,19-,20-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470541 (CHEMBL4280626) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C33H36N2O6/c1-3-22(2)28-29(41-33(28)39)31(37)34-26(19-23-13-7-4-8-14-23)30(36)35-27(20-24-15-9-5-10-16-24)32(38)40-21-25-17-11-6-12-18-25/h4-18,22,26-29H,3,19-21H2,1-2H3,(H,34,37)(H,35,36)/t22-,26-,27-,28-,29+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470551 (CHEMBL4280675) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1OC(=O)[C@H]1C1CCCC1)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C26H36N2O6/c1-15(2)20(27-24(30)22-19(25(31)34-22)18-12-8-9-13-18)23(29)28-21(16(3)4)26(32)33-14-17-10-6-5-7-11-17/h5-7,10-11,15-16,18-22H,8-9,12-14H2,1-4H3,(H,27,30)(H,28,29)/t19-,20-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470550 (CHEMBL4288920) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1OC(=O)[C@H]1C1CCC1)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C25H34N2O6/c1-14(2)19(26-23(29)21-18(24(30)33-21)17-11-8-12-17)22(28)27-20(15(3)4)25(31)32-13-16-9-6-5-7-10-16/h5-7,9-10,14-15,17-21H,8,11-13H2,1-4H3,(H,26,29)(H,27,28)/t18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470548 (CHEMBL4292745) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OC |r| Show InChI InChI=1S/C19H32N2O6/c1-8-11(6)12-15(27-18(12)24)17(23)20-13(9(2)3)16(22)21-14(10(4)5)19(25)26-7/h9-15H,8H2,1-7H3,(H,20,23)(H,21,22)/t11-,12-,13-,14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470545 (CHEMBL4289394) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCC1CCCCC1 |r| Show InChI InChI=1S/C25H42N2O6/c1-7-16(6)18-21(33-24(18)30)23(29)26-19(14(2)3)22(28)27-20(15(4)5)25(31)32-13-17-11-9-8-10-12-17/h14-21H,7-13H2,1-6H3,(H,26,29)(H,27,28)/t16-,18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50470539 (CHEMBL4293877) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C25H36N2O6/c1-7-16(6)18-21(33-24(18)30)23(29)26-19(14(2)3)22(28)27-20(15(4)5)25(31)32-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,28)/t16-,18-,19-,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470538 (CHEMBL4294463) Show SMILES CC(C)C[C@H]1[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C25H36N2O6/c1-14(2)12-18-21(33-24(18)30)23(29)26-19(15(3)4)22(28)27-20(16(5)6)25(31)32-13-17-10-8-7-9-11-17/h7-11,14-16,18-21H,12-13H2,1-6H3,(H,26,29)(H,27,28)/t18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470554 (CHEMBL4278670) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@H](C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1)C(C)(C)C |r| Show InChI InChI=1S/C26H38N2O6/c1-8-16(4)18-20(34-24(18)31)22(29)28-21(26(5,6)7)23(30)27-19(15(2)3)25(32)33-14-17-12-10-9-11-13-17/h9-13,15-16,18-21H,8,14H2,1-7H3,(H,27,30)(H,28,29)/t16-,18-,19-,20+,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277889 (CARFILZOMIB | CHEMBL451887) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470542 (CHEMBL4293806) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)OCc1ccccc1)C(C)(C)C)C(C)(C)C |r| Show InChI InChI=1S/C27H40N2O6/c1-9-16(2)18-19(35-24(18)32)22(30)28-20(26(3,4)5)23(31)29-21(27(6,7)8)25(33)34-15-17-13-11-10-12-14-17/h10-14,16,18-21H,9,15H2,1-8H3,(H,28,30)(H,29,31)/t16-,18-,19+,20+,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50470559 (CHEMBL4285979) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCC=C |r| Show InChI InChI=1S/C21H34N2O6/c1-8-10-28-21(27)16(12(5)6)23-18(24)15(11(3)4)22-19(25)17-14(13(7)9-2)20(26)29-17/h8,11-17H,1,9-10H2,2-7H3,(H,22,25)(H,23,24)/t13-,14-,15-,16-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50470543 (CHEMBL4286154) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1OC(=O)[C@H]1C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H34N2O6/c1-13(2)17-20(32-23(17)29)22(28)25-18(14(3)4)21(27)26-19(15(5)6)24(30)31-12-16-10-8-7-9-11-16/h7-11,13-15,17-20H,12H2,1-6H3,(H,25,28)(H,26,27)/t17-,18-,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50277889 (CARFILZOMIB | CHEMBL451887) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50145077 (CHEMBL3764535) Show SMILES O=C(c1[nH]c2[nH]c(CCCC#C)nc(=O)c2c1-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H19N3O2/c1-2-3-6-15-18-25-23-20(24(29)26-18)19(16-11-7-4-8-12-16)21(27-23)22(28)17-13-9-5-10-14-17/h1,4-5,7-14H,3,6,15H2,(H2,25,26,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Texas State University Curated by ChEMBL					Assay Description Inhibition of bovine tubulin assembly after 15 mins by turbidimetric analysis				J Med Chem 59: 480-5 (2016) Article DOI: 10.1021/acs.jmedchem.5b01426 BindingDB Entry DOI: 10.7270/Q2PV6N7Q
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470540 (CHEMBL4282642) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C22H30N2O6/c1-5-14(4)17-19(30-21(17)27)20(26)23-11-16(25)24-18(13(2)3)22(28)29-12-15-9-7-6-8-10-15/h6-10,13-14,17-19H,5,11-12H2,1-4H3,(H,23,26)(H,24,25)/t14-,17-,18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	261	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Texas State University Curated by ChEMBL					Assay Description Inhibition of bovine tubulin assembly after 15 mins by turbidimetric analysis				J Med Chem 59: 480-5 (2016) Article DOI: 10.1021/acs.jmedchem.5b01426 BindingDB Entry DOI: 10.7270/Q2PV6N7Q
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50470544 (CHEMBL4282765) Show SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1OC(=O)[C@H]1C(C)C)C(C)C)C(O)=O |r| Show InChI InChI=1S/C17H28N2O6/c1-7(2)10-13(25-17(10)24)15(21)18-11(8(3)4)14(20)19-12(9(5)6)16(22)23/h7-13H,1-6H3,(H,18,21)(H,19,20)(H,22,23)/t10-,11-,12-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	681	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470556 (CHEMBL4282576) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C30H38N2O7/c1-5-20(4)24-26(39-29(24)35)28(34)31-23(18-37-16-21-12-8-6-9-13-21)27(33)32-25(19(2)3)30(36)38-17-22-14-10-7-11-15-22/h6-15,19-20,23-26H,5,16-18H2,1-4H3,(H,31,34)(H,32,33)/t20-,23-,24-,25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	759	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Homo sapiens)	BDBM50470559 (CHEMBL4285979) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCC=C |r| Show InChI InChI=1S/C21H34N2O6/c1-8-10-28-21(27)16(12(5)6)23-18(24)15(11(3)4)22-19(25)17-14(13(7)9-2)20(26)29-17/h8,11-17H,1,9-10H2,2-7H3,(H,22,25)(H,23,24)/t13-,14-,15-,16-,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	779	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470544 (CHEMBL4282765) Show SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1OC(=O)[C@H]1C(C)C)C(C)C)C(O)=O |r| Show InChI InChI=1S/C17H28N2O6/c1-7(2)10-13(25-17(10)24)15(21)18-11(8(3)4)14(20)19-12(9(5)6)16(22)23/h7-13H,1-6H3,(H,18,21)(H,19,20)(H,22,23)/t10-,11-,12-,13+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Homo sapiens)	BDBM50277889 (CARFILZOMIB | CHEMBL451887) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Homo sapiens)	BDBM50277889 (CARFILZOMIB | CHEMBL451887) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Homo sapiens)	BDBM50470536 (CHEMBL4292798) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H37N3O5/c1-7-16(6)18-21(33-25(18)32)24(31)28-20(15(4)5)23(30)27-19(14(2)3)22(29)26-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,30)(H,28,31)/t16-,18-,19-,20-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470539 (CHEMBL4293877) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C25H36N2O6/c1-7-16(6)18-21(33-24(18)30)23(29)26-19(14(2)3)22(28)27-20(15(4)5)25(31)32-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,28)/t16-,18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470561 (CHEMBL4292698) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C26H38N2O6/c1-7-17(6)20-22(34-26(20)32)24(30)28-21(16(4)5)23(29)27-19(13-15(2)3)25(31)33-14-18-11-9-8-10-12-18/h8-12,15-17,19-22H,7,13-14H2,1-6H3,(H,27,29)(H,28,30)/t17-,19-,20-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470557 (CHEMBL4290778) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](COCc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C30H38N2O7/c1-5-20(4)24-26(39-30(24)36)28(34)32-25(19(2)3)27(33)31-23(18-37-16-21-12-8-6-9-13-21)29(35)38-17-22-14-10-7-11-15-22/h6-15,19-20,23-26H,5,16-18H2,1-4H3,(H,31,33)(H,32,34)/t20-,23-,24-,25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470553 (CHEMBL4282369) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C29H36N2O6/c1-5-19(4)23-25(37-29(23)35)27(33)31-24(18(2)3)26(32)30-22(16-20-12-8-6-9-13-20)28(34)36-17-21-14-10-7-11-15-21/h6-15,18-19,22-25H,5,16-17H2,1-4H3,(H,30,32)(H,31,33)/t19-,22-,23-,24-,25+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Homo sapiens)	BDBM50470539 (CHEMBL4293877) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C25H36N2O6/c1-7-16(6)18-21(33-24(18)30)23(29)26-19(14(2)3)22(28)27-20(15(4)5)25(31)32-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,28)/t16-,18-,19-,20-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470541 (CHEMBL4280626) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C33H36N2O6/c1-3-22(2)28-29(41-33(28)39)31(37)34-26(19-23-13-7-4-8-14-23)30(36)35-27(20-24-15-9-5-10-16-24)32(38)40-21-25-17-11-6-12-18-25/h4-18,22,26-29H,3,19-21H2,1-2H3,(H,34,37)(H,35,36)/t22-,26-,27-,28-,29+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Homo sapiens)	BDBM50470536 (CHEMBL4292798) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H37N3O5/c1-7-16(6)18-21(33-25(18)32)24(31)28-20(15(4)5)23(30)27-19(14(2)3)22(29)26-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,30)(H,28,31)/t16-,18-,19-,20-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470555 (CHEMBL4293394) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C26H38N2O6/c1-7-17(6)20-22(34-25(20)31)24(30)27-19(13-15(2)3)23(29)28-21(16(4)5)26(32)33-14-18-11-9-8-10-12-18/h8-12,15-17,19-22H,7,13-14H2,1-6H3,(H,27,30)(H,28,29)/t17-,19-,20-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50470549 (CHEMBL4286462) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1OC(=O)[C@H]1C1CC1)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H32N2O6/c1-13(2)18(25-22(28)20-17(16-10-11-16)23(29)32-20)21(27)26-19(14(3)4)24(30)31-12-15-8-6-5-7-9-15/h5-9,13-14,16-20H,10-12H2,1-4H3,(H,25,28)(H,26,27)/t17-,18-,19-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair

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