Compile Data Set for Download or QSAR

Found 134 hits with Last Name = 'rossetti' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326858 (CHEMBL1254556 | N-((3R,4R,5S,6R)-2,4-bis(4-chlorob...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@H](-[#7]-[#6](=O)-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C26H34Cl2N4O6/c1-35-15-20-23(34)24(36-13-16-4-8-18(27)9-5-16)22(32-21(33)3-2-12-31-26(29)30)25(38-20)37-14-17-6-10-19(28)11-7-17/h4-11,20,22-25,34H,2-3,12-15H2,1H3,(H,32,33)(H4,29,30,31)/t20-,22-,23-,24-,25?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326859 (CHEMBL1254630 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@H](-[#7]-[#6](=O)-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C30H37ClN4O6/c1-38-18-24-27(37)28(39-16-19-9-12-23(31)13-10-19)26(35-25(36)7-4-14-34-30(32)33)29(41-24)40-17-20-8-11-21-5-2-3-6-22(21)15-20/h2-3,5-6,8-13,15,24,26-29,37H,4,7,14,16-18H2,1H3,(H,35,36)(H4,32,33,34)/t24-,26-,27-,28-,29?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326860 (CHEMBL1254711 | N-((3R,4R,5S,6R)-2-(4-chlorobenzyl...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@H](-[#7]-[#6](=O)-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C30H37ClN4O6/c1-38-18-24-27(37)28(39-17-20-8-11-21-5-2-3-6-22(21)15-20)26(35-25(36)7-4-14-34-30(32)33)29(41-24)40-16-19-9-12-23(31)13-10-19/h2-3,5-6,8-13,15,24,26-29,37H,4,7,14,16-18H2,1H3,(H,35,36)(H4,32,33,34)/t24-,26-,27-,28-,29?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326861 (CHEMBL1254796 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6](-[#8]-[#6]-[#6]-c2ccccc2)-[#6@H](-[#7]-[#6](=O)-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C27H37ClN4O6/c1-35-17-21-24(34)25(37-16-19-9-11-20(28)12-10-19)23(32-22(33)8-5-14-31-27(29)30)26(38-21)36-15-13-18-6-3-2-4-7-18/h2-4,6-7,9-12,21,23-26,34H,5,8,13-17H2,1H3,(H,32,33)(H4,29,30,31)/t21-,23-,24-,25-,26?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326862 (4-(diaminomethyleneamino)-N-((3R,4R,5S,6R)-5-hydro...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@H](-[#7]-[#6](=O)-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C34H40N4O6/c1-41-21-28-31(40)32(42-19-22-12-14-24-7-2-4-9-26(24)17-22)30(38-29(39)11-6-16-37-34(35)36)33(44-28)43-20-23-13-15-25-8-3-5-10-27(25)18-23/h2-5,7-10,12-15,17-18,28,30-33,40H,6,11,16,19-21H2,1H3,(H,38,39)(H4,35,36,37)/t28-,30-,31-,32-,33?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326863 (3-(diaminomethyleneamino)-N-((3R,4R,5S,6R)-5-hydro...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@H](-[#7]-[#6](=O)-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C33H38N4O6/c1-40-20-27-30(39)31(41-18-21-10-12-23-6-2-4-8-25(23)16-21)29(37-28(38)14-15-36-33(34)35)32(43-27)42-19-22-11-13-24-7-3-5-9-26(24)17-22/h2-13,16-17,27,29-32,39H,14-15,18-20H2,1H3,(H,37,38)(H4,34,35,36)/t27-,29-,30-,31-,32?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326864 (CHEMBL1254883 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6](-[#8]-[#6]-c2ccc3ccccc3c2)-[#6@H](-[#7]-[#6](=O)-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C28H33ClN4O6/c1-36-16-22-25(35)26(37-14-17-7-10-21(29)11-8-17)24(33-23(34)13-32-28(30)31)27(39-22)38-15-18-6-9-19-4-2-3-5-20(19)12-18/h2-12,22,24-27,35H,13-16H2,1H3,(H,33,34)(H4,30,31,32)/t22-,24-,25-,26-,27?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607682 (CHEMBL5220685) Show SMILES COC(=O)[C@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607676 (CHEMBL5218698) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607678 (CHEMBL5218878) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCNC(=O)C1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607681 (CHEMBL5218552) Show SMILES COC(=O)[C@@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607679 (CHEMBL5218615) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCS(=O)(=O)CC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607682 (CHEMBL5220685) Show SMILES COC(=O)[C@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607683 (CHEMBL5219579) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607686 (CHEMBL5219830) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607676 (CHEMBL5218698) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607680 (CHEMBL5218702) Show SMILES CC1(O)CCN(CCOc2ccccc2Cc2cn(nc2-c2cc(Cl)nc(N)n2)C(F)F)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607685 (CHEMBL5220647) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607686 (CHEMBL5219830) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607678 (CHEMBL5218878) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCNC(=O)C1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607684 (CHEMBL5219443) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607673 (CHEMBL5220895) Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3CC(C2)O3)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607674 (CHEMBL5220347) Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3(COC3)C2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607685 (CHEMBL5220647) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607672 (CHEMBL5220723) Show SMILES Cn1cc(Cc2ccccc2OCCN2CCOCC2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607679 (CHEMBL5218615) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCS(=O)(=O)CC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607675 (CHEMBL5219922) Show SMILES Cn1cc(Cc2ccccc2OCCN2CCNC(=O)C2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607680 (CHEMBL5218702) Show SMILES CC1(O)CCN(CCOc2ccccc2Cc2cn(nc2-c2cc(Cl)nc(N)n2)C(F)F)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607681 (CHEMBL5218552) Show SMILES COC(=O)[C@@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607667 (CHEMBL5219530) Show SMILES COC(=O)c1ccccc1Cc1cn(C)nc1-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607684 (CHEMBL5219443) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607677 (CHEMBL5220632) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCC(=O)N1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577248 (CHEMBL4878379) Show SMILES COC(=O)c1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607683 (CHEMBL5219579) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607677 (CHEMBL5220632) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCC(=O)N1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50326854 ((Naphth-2-yl)methyl-2-(4'-Aminobutyrylamido)-3-O-(...) Show SMILES COC[C@H]1O[C@@H](OCc2ccc3ccccc3c2)[C@H](NC(=O)CCCN)[C@@H](OCc2ccc(Cl)cc2)[C@@H]1O |r| Show InChI InChI=1S/C29H35ClN2O6/c1-35-18-24-27(34)28(36-16-19-9-12-23(30)13-10-19)26(32-25(33)7-4-14-31)29(38-24)37-17-20-8-11-21-5-2-3-6-22(21)15-20/h2-3,5-6,8-13,15,24,26-29,34H,4,7,14,16-18,31H2,1H3,(H,32,33)/t24-,26-,27-,28-,29-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cells				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607660 (CHEMBL5221008) Show SMILES Cn1cc(Cc2ccccc2Cl)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607666 (CHEMBL5220075) Show SMILES COc1ccccc1Cc1cn(C)nc1-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50326878 ((2R,3S,5R)-5-(3-aminopropylamino)-4-(4-chlorobenzy...) Show SMILES COC[C@H]1OC(OCc2ccc3ccccc3c2)[C@H](NCCCN)C(OCc2ccc(Cl)cc2)[C@@H]1O |r| Show InChI InChI=1S/C28H35ClN2O5/c1-33-18-24-26(32)27(34-16-19-8-11-23(29)12-9-19)25(31-14-4-13-30)28(36-24)35-17-20-7-10-21-5-2-3-6-22(21)15-20/h2-3,5-12,15,24-28,31-32H,4,13-14,16-18,30H2,1H3/t24-,25-,26-,27?,28?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cells				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50326872 (CHEMBL1254140 | Naphth-2-yl)methyl-2-(4'-Aminobuty...) Show SMILES COC[C@H]1O[C@H](OCc2ccc3ccccc3c2)[C@H](NC(=O)CCCN)[C@H](OCc2ccc(Cl)cc2)[C@@H]1O |r| Show InChI InChI=1S/C29H35ClN2O6/c1-35-18-24-27(34)28(36-16-19-9-12-23(30)13-10-19)26(32-25(33)7-4-14-31)29(38-24)37-17-20-8-11-21-5-2-3-6-22(21)15-20/h2-3,5-6,8-13,15,24,26-29,34H,4,7,14,16-18,31H2,1H3,(H,32,33)/t24-,26-,27-,28+,29+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cells				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607671 (CHEMBL5221093) Show SMILES Cn1cc(Cc2ccccc2Oc2ccccc2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50326879 ((2R,3S,5R)-5-(2-aminoethylamino)-2-(methoxymethyl)...) Show SMILES COC[C@H]1OC(OCc2ccc3ccccc3c2)[C@H](NCCN)C(OCc2cccc3ccccc23)[C@@H]1O |r| Show InChI InChI=1S/C31H36N2O5/c1-35-20-27-29(34)30(36-19-25-11-6-10-23-8-4-5-12-26(23)25)28(33-16-15-32)31(38-27)37-18-21-13-14-22-7-2-3-9-24(22)17-21/h2-14,17,27-31,33-34H,15-16,18-20,32H2,1H3/t27-,28-,29-,30?,31?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cells				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577243 (CHEMBL4868801) Show SMILES Cc1c(Cc2cccc(Cl)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607662 (CHEMBL5219193) Show SMILES Nc1nc(Cl)cc(n1)-c1nn2ccccc2c1Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50326865 ((4'-Chlorobenzyl)3-O-(4'-Chlorobenzyl)-2-deoxy-2-(...) Show SMILES [#6]-[#8]-[#6]-[#6@H]-1-[#8]-[#6@H](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@H](-[#7]-[#6](=O)-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8]-[#6]-c2ccc(Cl)cc2)-[#6@@H]-1-[#8] |r| Show InChI InChI=1S/C26H34Cl2N4O6/c1-35-15-20-23(34)24(36-13-16-4-8-18(27)9-5-16)22(32-21(33)3-2-12-31-26(29)30)25(38-20)37-14-17-6-10-19(28)11-7-17/h4-11,20,22-25,34H,2-3,12-15H2,1H3,(H,32,33)(H4,29,30,31)/t20-,22-,23-,24-,25+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Alchemia Ltd Curated by ChEMBL					Assay Description Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 5576-86 (2010) Article DOI: 10.1021/jm1002777 BindingDB Entry DOI: 10.7270/Q2QC03QK
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577244 (CHEMBL4864668) Show SMILES Cc1c(Cc2cccc(F)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577236 (CHEMBL4857305) Show SMILES Cn1cc(Cc2ccccc2F)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 134 total )  |  Next  |  Last  >>

Jump to: