Compile Data Set for Download or QSAR

Found 206 hits with Last Name = 'roussi' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM21447 (4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...) Show SMILES CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1 |r| Show InChI InChI=1S/C42H45ClN6O5S2/c1-46(2)23-22-35(30-55-37-9-4-3-5-10-37)44-40-21-20-38(28-41(40)49(51)52)56(53,54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21,28,35,44H,22-27,29-30H2,1-2H3,(H,45,50)/t35-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie des Substances Naturelles (ICSN) Curated by ChEMBL					Assay Description Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assay				J Nat Prod 77: 1430-7 (2014) Article DOI: 10.1021/np500170v BindingDB Entry DOI: 10.7270/Q2R212XF
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314864 (CHEMBL4172927) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Oc4ccc(NC(=O)COc5ccc(C)cc5)cc4)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:37,t:55| Show InChI InChI=1S/C45H42ClNO9/c1-28-3-13-37(14-4-28)55-27-41(48)47-36-11-17-39(18-12-36)56-38-15-9-33(10-16-38)43(51)54-22-20-30-19-21-45(44(52)53)34(25-30)23-29(2)24-35(45)26-40(46)31-5-7-32(8-6-31)42(49)50/h3-19,21,24,26,30,34-35H,20,22-23,25,27H2,1-2H3,(H,47,48)(H,49,50)(H,52,53)/b40-26-/t30-,34-,35-,45-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314865 (CHEMBL4172616) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Oc4cccnc4)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:24,t:42| Show InChI InChI=1S/C35H32ClNO7/c1-22-17-27-19-23(13-16-43-33(40)26-8-10-29(11-9-26)44-30-3-2-15-37-21-30)12-14-35(27,34(41)42)28(18-22)20-31(36)24-4-6-25(7-5-24)32(38)39/h2-12,14-15,18,20-21,23,27-28H,13,16-17,19H2,1H3,(H,38,39)(H,41,42)/b31-20-/t23-,27-,28-,35-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50314865 (CHEMBL4172616) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Oc4cccnc4)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:24,t:42| Show InChI InChI=1S/C35H32ClNO7/c1-22-17-27-19-23(13-16-43-33(40)26-8-10-29(11-9-26)44-30-3-2-15-37-21-30)12-14-35(27,34(41)42)28(18-22)20-31(36)24-4-6-25(7-5-24)32(38)39/h2-12,14-15,18,20-21,23,27-28H,13,16-17,19H2,1H3,(H,38,39)(H,41,42)/b31-20-/t23-,27-,28-,35-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-AhxBak-OH binding to human 45-84/C37 Bcl-xL after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541325 (CHEMBL4644062) Show SMILES [#6]-[#8]-[#7](-[#6])-[#6](=O)-[#6@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-c1ccccc1 |r,t:8| Show InChI InChI=1S/C21H29NO2/c1-16(2)9-8-10-17-13-14-19(21(23)22(3)24-4)20(15-17)18-11-6-5-7-12-18/h5-7,9,11-13,19-20H,8,10,14-15H2,1-4H3/t19-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314860 (CHEMBL4161200) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3cccc(Br)c3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29BrClNO6/c1-18-13-22-15-19(10-12-39-29(38)33-25-4-2-3-24(31)17-25)9-11-30(22,28(36)37)23(14-18)16-26(32)20-5-7-21(8-6-20)27(34)35/h2-9,11,14,16-17,19,22-23H,10,12-13,15H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-16-/t19-,22-,23-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314860 (CHEMBL4161200) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3cccc(Br)c3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29BrClNO6/c1-18-13-22-15-19(10-12-39-29(38)33-25-4-2-3-24(31)17-25)9-11-30(22,28(36)37)23(14-18)16-26(32)20-5-7-21(8-6-20)27(34)35/h2-9,11,14,16-17,19,22-23H,10,12-13,15H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-16-/t19-,22-,23-,30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314863 (CHEMBL4162253) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:17,t:35| Show InChI InChI=1S/C30H28Cl2O6/c1-18-14-23-16-19(11-13-38-28(35)22-6-8-25(31)9-7-22)10-12-30(23,29(36)37)24(15-18)17-26(32)20-2-4-21(5-3-20)27(33)34/h2-10,12,15,17,19,23-24H,11,13-14,16H2,1H3,(H,33,34)(H,36,37)/b26-17-/t19-,23-,24-,30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314859 (CHEMBL4169123) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(Br)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29BrClNO6/c1-18-14-22-16-19(11-13-39-29(38)33-25-8-6-24(31)7-9-25)10-12-30(22,28(36)37)23(15-18)17-26(32)20-2-4-21(5-3-20)27(34)35/h2-10,12,15,17,19,22-23H,11,13-14,16H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-17-/t19-,22-,23-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314864 (CHEMBL4172927) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Oc4ccc(NC(=O)COc5ccc(C)cc5)cc4)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:37,t:55| Show InChI InChI=1S/C45H42ClNO9/c1-28-3-13-37(14-4-28)55-27-41(48)47-36-11-17-39(18-12-36)56-38-15-9-33(10-16-38)43(51)54-22-20-30-19-21-45(44(52)53)34(25-30)23-29(2)24-35(45)26-40(46)31-5-7-32(8-6-31)42(49)50/h3-19,21,24,26,30,34-35H,20,22-23,25,27H2,1-2H3,(H,47,48)(H,49,50)(H,52,53)/b40-26-/t30-,34-,35-,45-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314863 (CHEMBL4162253) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:17,t:35| Show InChI InChI=1S/C30H28Cl2O6/c1-18-14-23-16-19(11-13-38-28(35)22-6-8-25(31)9-7-22)10-12-30(23,29(36)37)24(15-18)17-26(32)20-2-4-21(5-3-20)27(33)34/h2-10,12,15,17,19,23-24H,11,13-14,16H2,1H3,(H,33,34)(H,36,37)/b26-17-/t19-,23-,24-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50314863 (CHEMBL4162253) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:17,t:35| Show InChI InChI=1S/C30H28Cl2O6/c1-18-14-23-16-19(11-13-38-28(35)22-6-8-25(31)9-7-22)10-12-30(23,29(36)37)24(15-18)17-26(32)20-2-4-21(5-3-20)27(33)34/h2-10,12,15,17,19,23-24H,11,13-14,16H2,1H3,(H,33,34)(H,36,37)/b26-17-/t19-,23-,24-,30-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-AhxBak-OH binding to human 45-84/C37 Bcl-xL after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50315690 (CHEMBL4177447) Show SMILES [H][C@]12C[C@H](CCn3cc(nn3)-c3ccccc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:19,t:37| Show InChI InChI=1S/C31H30ClN3O4/c1-20-15-25-17-21(12-14-35-19-28(33-34-35)23-5-3-2-4-6-23)11-13-31(25,30(38)39)26(16-20)18-27(32)22-7-9-24(10-8-22)29(36)37/h2-11,13,16,18-19,21,25-26H,12,14-15,17H2,1H3,(H,36,37)(H,38,39)/b27-18-/t21-,25-,26-,31-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541331 (CHEMBL4636501) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6@@H](-[#6@H](-[#6]-1)-c1ccccc1)-[#6](=O)-[#7]-[#8] |r,t:6| Show InChI InChI=1S/C19H25NO2/c1-14(2)7-6-8-15-11-12-17(19(21)20-22)18(13-15)16-9-4-3-5-10-16/h3-5,7,9-11,17-18,22H,6,8,12-13H2,1-2H3,(H,20,21)/t17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314873 (CHEMBL4174087) Show SMILES [H][C@]12C[C@H](CC(=O)NCc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(=O)OC |r,c:17,t:35| Show InChI InChI=1S/C31H31Cl2NO5/c1-19-13-24-15-21(16-28(35)34-18-20-3-9-26(32)10-4-20)11-12-31(24,30(38)39-2)25(14-19)17-27(33)22-5-7-23(8-6-22)29(36)37/h3-12,14,17,21,24-25H,13,15-16,18H2,1-2H3,(H,34,35)(H,36,37)/b27-17-/t21-,24+,25+,31+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Frog rectus Abdominis Muscle				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314874 (CHEMBL4176611) Show SMILES [H][C@]12C[C@H](CC(=O)Nc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(=O)OC |r,c:16,t:34| Show InChI InChI=1S/C30H29Cl2NO5/c1-18-13-22-15-19(16-27(34)33-25-9-7-24(31)8-10-25)11-12-30(22,29(37)38-2)23(14-18)17-26(32)20-3-5-21(6-4-20)28(35)36/h3-12,14,17,19,22-23H,13,15-16H2,1-2H3,(H,33,34)(H,35,36)/b26-17-/t19-,22+,23+,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541332 (CHEMBL4635324) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6@H](-[#6@@H](-[#6]-1)-c1ccccc1)-[#6](=O)-[#7]-[#8] |r,t:6| Show InChI InChI=1S/C19H25NO2/c1-14(2)7-6-8-15-11-12-17(19(21)20-22)18(13-15)16-9-4-3-5-10-16/h3-5,7,9-11,17-18,22H,6,8,12-13H2,1-2H3,(H,20,21)/t17-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314870 (CHEMBL4160019) Show SMILES [H][C@]12C[C@H](CC(=O)NCc3cccnc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(=O)OC)C=C(C)C2)C(=O)OC |r,c:16,t:35| Show InChI InChI=1S/C31H33ClN2O5/c1-20-13-25-15-21(16-28(35)34-19-22-5-4-12-33-18-22)10-11-31(25,30(37)39-3)26(14-20)17-27(32)23-6-8-24(9-7-23)29(36)38-2/h4-12,14,17-18,21,25-26H,13,15-16,19H2,1-3H3,(H,34,35)/b27-17-/t21-,25+,26+,31+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Frog rectus Abdominis Muscle				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314859 (CHEMBL4169123) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(Br)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29BrClNO6/c1-18-14-22-16-19(11-13-39-29(38)33-25-8-6-24(31)7-9-25)10-12-30(22,28(36)37)23(15-18)17-26(32)20-2-4-21(5-3-20)27(34)35/h2-10,12,15,17,19,22-23H,11,13-14,16H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-17-/t19-,22-,23-,30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50314860 (CHEMBL4161200) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3cccc(Br)c3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29BrClNO6/c1-18-13-22-15-19(10-12-39-29(38)33-25-4-2-3-24(31)17-25)9-11-30(22,28(36)37)23(14-18)16-26(32)20-5-7-21(8-6-20)27(34)35/h2-9,11,14,16-17,19,22-23H,10,12-13,15H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-16-/t19-,22-,23-,30-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-AhxBak-OH binding to human 45-84/C37 Bcl-xL after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50541325 (CHEMBL4644062) Show SMILES [#6]-[#8]-[#7](-[#6])-[#6](=O)-[#6@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-c1ccccc1 |r,t:8| Show InChI InChI=1S/C21H29NO2/c1-16(2)9-8-10-17-13-14-19(21(23)22(3)24-4)20(15-17)18-11-6-5-7-12-18/h5-7,9,11-13,19-20H,8,10,14-15H2,1-4H3/t19-,20+/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Mcl-1 (unknown origin)/Bid interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 m...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314874 (CHEMBL4176611) Show SMILES [H][C@]12C[C@H](CC(=O)Nc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(=O)OC |r,c:16,t:34| Show InChI InChI=1S/C30H29Cl2NO5/c1-18-13-22-15-19(16-27(34)33-25-9-7-24(31)8-10-25)11-12-30(22,29(37)38-2)23(14-18)17-26(32)20-3-5-21(6-4-20)28(35)36/h3-12,14,17,19,22-23H,13,15-16H2,1-2H3,(H,33,34)(H,35,36)/b26-17-/t19-,22+,23+,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314862 (CHEMBL4169534) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3cccc(Cl)c3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29Cl2NO6/c1-18-13-22-15-19(10-12-39-29(38)33-25-4-2-3-24(31)17-25)9-11-30(22,28(36)37)23(14-18)16-26(32)20-5-7-21(8-6-20)27(34)35/h2-9,11,14,16-17,19,22-23H,10,12-13,15H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-16-/t19-,22-,23-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314862 (CHEMBL4169534) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3cccc(Cl)c3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29Cl2NO6/c1-18-13-22-15-19(10-12-39-29(38)33-25-4-2-3-24(31)17-25)9-11-30(22,28(36)37)23(14-18)16-26(32)20-5-7-21(8-6-20)27(34)35/h2-9,11,14,16-17,19,22-23H,10,12-13,15H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-16-/t19-,22-,23-,30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314861 (CHEMBL4177395) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29Cl2NO6/c1-18-14-22-16-19(11-13-39-29(38)33-25-8-6-24(31)7-9-25)10-12-30(22,28(36)37)23(15-18)17-26(32)20-2-4-21(5-3-20)27(34)35/h2-10,12,15,17,19,22-23H,11,13-14,16H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-17-/t19-,22-,23-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314861 (CHEMBL4177395) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29Cl2NO6/c1-18-14-22-16-19(11-13-39-29(38)33-25-8-6-24(31)7-9-25)10-12-30(22,28(36)37)23(15-18)17-26(32)20-2-4-21(5-3-20)27(34)35/h2-10,12,15,17,19,22-23H,11,13-14,16H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-17-/t19-,22-,23-,30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50315549 (CHEMBL4175537) Show SMILES [H][C@]12C[C@H](CCN=[N+]=[N-])C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(=O)OCOC(C)=O)C=C(C)C2)C(=O)OCOC(C)=O |r,c:9,t:32| Show InChI InChI=1S/C29H32ClN3O8/c1-18-12-24-14-21(9-11-32-33-31)8-10-29(24,28(37)41-17-39-20(3)35)25(13-18)15-26(30)22-4-6-23(7-5-22)27(36)40-16-38-19(2)34/h4-8,10,13,15,21,24-25H,9,11-12,14,16-17H2,1-3H3/b26-15-/t21-,24-,25-,29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314866 (CHEMBL4161959) Show SMILES [H][C@@]1(C[C@]2([H])CC(C)=C[C@@H](\C=C(/C)[C@H]3CCC(CC3)C(O)=O)[C@@]2(C=C1)C(O)=O)[C@@H](C)CCC=C(C)C |r,wU:1.0,28.31,wD:3.3,9.9,13.12,22.27,c:7,25,(10.46,-2.76,;10.48,-4.31,;9.14,-3.52,;7.81,-4.3,;7.8,-2.76,;6.48,-3.51,;5.15,-4.3,;3.82,-3.53,;5.15,-5.84,;6.48,-6.59,;6.49,-8.13,;5.15,-8.91,;3.82,-8.14,;5.15,-10.45,;3.81,-11.21,;3.81,-12.74,;5.14,-13.52,;6.48,-12.75,;6.49,-11.2,;5.14,-15.06,;3.8,-15.82,;6.47,-15.83,;7.81,-5.84,;9.13,-6.6,;10.47,-5.85,;8.2,-7.31,;7.42,-8.64,;9.74,-7.31,;11.81,-3.54,;11.82,-2,;13.14,-4.32,;14.48,-3.55,;15.81,-4.33,;17.15,-3.57,;18.48,-4.35,;17.16,-2.03,)| Show InChI InChI=1S/C30H44O4/c1-19(2)7-6-8-21(4)25-13-14-30(29(33)34)26(15-20(3)16-27(30)18-25)17-22(5)23-9-11-24(12-10-23)28(31)32/h7,13-15,17,21,23-27H,6,8-12,16,18H2,1-5H3,(H,31,32)(H,33,34)/b22-17+/t21-,23-,24?,25+,26-,27-,30+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541353 (CHEMBL4640455) Show SMILES [H][C@@]1(C[C@]2([H])CC(C)=C[C@@H](\C=C(/C)[C@H]3CC[C@@H](CC3)C(O)=O)[C@@]2(C=C1)C(O)=O)[C@@H](C)CCC=C(C)C |r,wU:28.31,1.0,16.19,wD:3.3,22.27,9.9,13.12,c:7,25,(36.45,-22.49,;36.46,-24.04,;35.13,-23.25,;33.81,-24.03,;33.79,-22.49,;32.48,-23.24,;31.15,-24.03,;29.81,-23.26,;31.15,-25.57,;32.48,-26.32,;31.37,-27.42,;29.88,-27.01,;29.5,-25.52,;28.79,-28.09,;27.31,-27.67,;26.22,-28.75,;26.6,-30.24,;28.08,-30.65,;29.19,-29.57,;25.49,-31.32,;24.01,-30.9,;25.87,-32.82,;33.8,-25.57,;35.11,-26.33,;36.45,-25.58,;33.78,-27.1,;32.44,-27.85,;35.1,-27.88,;37.8,-23.27,;37.81,-21.73,;39.13,-24.05,;40.47,-23.28,;41.8,-24.07,;43.14,-23.3,;44.47,-24.08,;43.15,-21.76,)| Show InChI InChI=1S/C30H44O4/c1-19(2)7-6-8-21(4)25-13-14-30(29(33)34)26(15-20(3)16-27(30)18-25)17-22(5)23-9-11-24(12-10-23)28(31)32/h7,13-15,17,21,23-27H,6,8-12,16,18H2,1-5H3,(H,31,32)(H,33,34)/b22-17+/t21-,23-,24-,25+,26-,27-,30+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314855 (CHEMBL4176314) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(cc3)C(C)=O)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:20,t:38| Show InChI InChI=1S/C32H32ClNO7/c1-19-15-25-17-21(12-14-41-31(40)34-27-9-7-22(8-10-27)20(2)35)11-13-32(25,30(38)39)26(16-19)18-28(33)23-3-5-24(6-4-23)29(36)37/h3-11,13,16,18,21,25-26H,12,14-15,17H2,1-2H3,(H,34,40)(H,36,37)(H,38,39)/b28-18-/t21-,25-,26-,32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50315690 (CHEMBL4177447) Show SMILES [H][C@]12C[C@H](CCn3cc(nn3)-c3ccccc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:19,t:37| Show InChI InChI=1S/C31H30ClN3O4/c1-20-15-25-17-21(12-14-35-19-28(33-34-35)23-5-3-2-4-6-23)11-13-31(25,30(38)39)26(16-20)18-27(32)22-7-9-24(10-8-22)29(36)37/h2-11,13,16,18-19,21,25-26H,12,14-15,17H2,1H3,(H,36,37)(H,38,39)/b27-18-/t21-,25-,26-,31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314865 (CHEMBL4172616) Show SMILES [H][C@]12C[C@H](CCOC(=O)c3ccc(Oc4cccnc4)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:24,t:42| Show InChI InChI=1S/C35H32ClNO7/c1-22-17-27-19-23(13-16-43-33(40)26-8-10-29(11-9-26)44-30-3-2-15-37-21-30)12-14-35(27,34(41)42)28(18-22)20-31(36)24-4-6-25(7-5-24)32(38)39/h2-12,14-15,18,20-21,23,27-28H,13,16-17,19H2,1H3,(H,38,39)(H,41,42)/b31-20-/t23-,27-,28-,35-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314877 (CHEMBL4171691) Show SMILES [H][C@]12C[C@H](CC(O)=O)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(=O)OCOC(C)=O)C=C(C)C2)C(=O)OCOC(C)=O |r,c:8,t:31| Show InChI InChI=1S/C29H31ClO10/c1-17-10-23-12-20(13-26(33)34)8-9-29(23,28(36)40-16-38-19(3)32)24(11-17)14-25(30)21-4-6-22(7-5-21)27(35)39-15-37-18(2)31/h4-9,11,14,20,23-24H,10,12-13,15-16H2,1-3H3,(H,33,34)/b25-14-/t20-,23+,24+,29+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50314855 (CHEMBL4176314) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(cc3)C(C)=O)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:20,t:38| Show InChI InChI=1S/C32H32ClNO7/c1-19-15-25-17-21(12-14-41-31(40)34-27-9-7-22(8-10-27)20(2)35)11-13-32(25,30(38)39)26(16-19)18-28(33)23-3-5-24(6-4-23)29(36)37/h3-11,13,16,18,21,25-26H,12,14-15,17H2,1-2H3,(H,34,40)(H,36,37)(H,38,39)/b28-18-/t21-,25-,26-,32-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-AhxBak-OH binding to human 45-84/C37 Bcl-xL after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50315693 (CHEMBL4166826) Show SMILES [H][C@]12C[C@H](CCn3cc(Cc4ccccc4)nn3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:20,t:38| Show InChI InChI=1S/C32H32ClN3O4/c1-21-15-26-17-23(12-14-36-20-28(34-35-36)18-22-5-3-2-4-6-22)11-13-32(26,31(39)40)27(16-21)19-29(33)24-7-9-25(10-8-24)30(37)38/h2-11,13,16,19-20,23,26-27H,12,14-15,17-18H2,1H3,(H,37,38)(H,39,40)/b29-19-/t23-,26-,27-,32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541329 (CHEMBL4632968) Show SMILES [#6]-[#7](-[#8])-[#6](=O)-[#6@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-c1ccccc1 |r,t:7| Show InChI InChI=1S/C20H27NO2/c1-15(2)8-7-9-16-12-13-18(20(22)21(3)23)19(14-16)17-10-5-4-6-11-17/h4-6,8,10-12,18-19,23H,7,9,13-14H2,1-3H3/t18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50314859 (CHEMBL4169123) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(Br)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:18,t:36| Show InChI InChI=1S/C30H29BrClNO6/c1-18-14-22-16-19(11-13-39-29(38)33-25-8-6-24(31)7-9-25)10-12-30(22,28(36)37)23(15-18)17-26(32)20-2-4-21(5-3-20)27(34)35/h2-10,12,15,17,19,22-23H,11,13-14,16H2,1H3,(H,33,38)(H,34,35)(H,36,37)/b26-17-/t19-,22-,23-,30-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-AhxBak-OH binding to human 45-84/C37 Bcl-xL after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541346 (CHEMBL4648756) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6@H](-[#6@@H](-[#6]-1)-c1ccccc1)-[#6](=O)-[#7]-c1ccc(cc1)-[#6](-[#8])=O |r,t:6| Show InChI InChI=1S/C26H29NO3/c1-18(2)7-6-8-19-11-16-23(24(17-19)20-9-4-3-5-10-20)25(28)27-22-14-12-21(13-15-22)26(29)30/h3-5,7,9-15,23-24H,6,8,16-17H2,1-2H3,(H,27,28)(H,29,30)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50315693 (CHEMBL4166826) Show SMILES [H][C@]12C[C@H](CCn3cc(Cc4ccccc4)nn3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:20,t:38| Show InChI InChI=1S/C32H32ClN3O4/c1-21-15-26-17-23(12-14-36-20-28(34-35-36)18-22-5-3-2-4-6-22)11-13-32(26,31(39)40)27(16-21)19-29(33)24-7-9-25(10-8-24)30(37)38/h2-11,13,16,19-20,23,26-27H,12,14-15,17-18H2,1H3,(H,37,38)(H,39,40)/b29-19-/t23-,26-,27-,32-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50315549 (CHEMBL4175537) Show SMILES [H][C@]12C[C@H](CCN=[N+]=[N-])C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(=O)OCOC(C)=O)C=C(C)C2)C(=O)OCOC(C)=O |r,c:9,t:32| Show InChI InChI=1S/C29H32ClN3O8/c1-18-12-24-14-21(9-11-32-33-31)8-10-29(24,28(37)41-17-39-20(3)35)25(13-18)15-26(30)22-4-6-23(7-5-22)27(36)40-16-38-19(2)34/h4-8,10,13,15,21,24-25H,9,11-12,14,16-17H2,1-3H3/b26-15-/t21-,24-,25-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541330 (CHEMBL4646779) Show SMILES [#6]-[#7](-[#8])-[#6](=O)-[#6@@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@H]-1-c1ccccc1 |r,t:7| Show InChI InChI=1S/C20H27NO2/c1-15(2)8-7-9-16-12-13-18(20(22)21(3)23)19(14-16)17-10-5-4-6-11-17/h4-6,8,10-12,18-19,23H,7,9,13-14H2,1-3H3/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541327 (CHEMBL4640382) Show SMILES [#6]-[#8]-[#7]-[#6](=O)-[#6@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-c1ccccc1 |r,t:7| Show InChI InChI=1S/C20H27NO2/c1-15(2)8-7-9-16-12-13-18(20(22)21-23-3)19(14-16)17-10-5-4-6-11-17/h4-6,8,10-12,18-19H,7,9,13-14H2,1-3H3,(H,21,22)/t18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50315690 (CHEMBL4177447) Show SMILES [H][C@]12C[C@H](CCn3cc(nn3)-c3ccccc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:19,t:37| Show InChI InChI=1S/C31H30ClN3O4/c1-20-15-25-17-21(12-14-35-19-28(33-34-35)23-5-3-2-4-6-23)11-13-31(25,30(38)39)26(16-20)18-27(32)22-7-9-24(10-8-22)29(36)37/h2-11,13,16,18-19,21,25-26H,12,14-15,17H2,1H3,(H,36,37)(H,38,39)/b27-18-/t21-,25-,26-,31-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50315670 (CHEMBL4164915) Show SMILES [H][C@]12C[C@H](CCn3cc(nn3)-c3ccccc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(=O)OCOC(C)=O)C=C(C)C2)C(=O)OCOC(C)=O |r,c:19,t:42| Show InChI InChI=1S/C37H38ClN3O8/c1-24-17-31-19-27(14-16-41-21-34(39-40-41)29-7-5-4-6-8-29)13-15-37(31,36(45)49-23-47-26(3)43)32(18-24)20-33(38)28-9-11-30(12-10-28)35(44)48-22-46-25(2)42/h4-13,15,18,20-21,27,31-32H,14,16-17,19,22-23H2,1-3H3/b33-20-/t27-,31-,32-,37-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541328 (CHEMBL4646299) Show SMILES [#6]-[#8]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@H]-1-c1ccccc1 |r,t:7| Show InChI InChI=1S/C20H27NO2/c1-15(2)8-7-9-16-12-13-18(20(22)21-23-3)19(14-16)17-10-5-4-6-11-17/h4-6,8,10-12,18-19H,7,9,13-14H2,1-3H3,(H,21,22)/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50314873 (CHEMBL4174087) Show SMILES [H][C@]12C[C@H](CC(=O)NCc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(=O)OC |r,c:17,t:35| Show InChI InChI=1S/C31H31Cl2NO5/c1-19-13-24-15-21(16-28(35)34-18-20-3-9-26(32)10-4-20)11-12-31(24,30(38)39-2)25(14-19)17-27(33)22-5-7-23(8-6-22)29(36)37/h3-12,14,17,21,24-25H,13,15-16,18H2,1-2H3,(H,34,35)(H,36,37)/b27-17-/t21-,24+,25+,31+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Frog rectus Abdominis Muscle				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50314874 (CHEMBL4176611) Show SMILES [H][C@]12C[C@H](CC(=O)Nc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(=O)OC |r,c:16,t:34| Show InChI InChI=1S/C30H29Cl2NO5/c1-18-13-22-15-19(16-27(34)33-25-9-7-24(31)8-10-25)11-12-30(22,29(37)38-2)23(14-18)17-26(32)20-3-5-21(6-4-20)28(35)36/h3-12,14,17,19,22-23H,13,15-16H2,1-2H3,(H,33,34)(H,35,36)/b26-17-/t19-,22+,23+,30+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Frog rectus Abdominis Muscle				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50314855 (CHEMBL4176314) Show SMILES [H][C@]12C[C@H](CCOC(=O)Nc3ccc(cc3)C(C)=O)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(O)=O |r,c:20,t:38| Show InChI InChI=1S/C32H32ClNO7/c1-19-15-25-17-21(12-14-41-31(40)34-27-9-7-22(8-10-27)20(2)35)11-13-32(25,30(38)39)26(16-19)18-28(33)23-3-5-24(6-4-23)29(36)37/h3-11,13,16,18,21,25-26H,12,14-15,17H2,1-2H3,(H,34,40)(H,36,37)(H,38,39)/b28-18-/t21-,25-,26-,32-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assay				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541337 (CHEMBL4640677) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-[#6]-[#7]-[#6](=O)-[#6@H]-1-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-c1ccccc1 |r,t:11| Show InChI InChI=1S/C23H31NO3/c1-17(2)8-7-9-18-12-13-20(23(26)24-15-14-22(25)27-3)21(16-18)19-10-5-4-6-11-19/h4-6,8,10-12,20-21H,7,9,13-16H2,1-3H3,(H,24,26)/t20-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
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Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50314877 (CHEMBL4171691) Show SMILES [H][C@]12C[C@H](CC(O)=O)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(=O)OCOC(C)=O)C=C(C)C2)C(=O)OCOC(C)=O |r,c:8,t:31| Show InChI InChI=1S/C29H31ClO10/c1-17-10-23-12-20(13-26(33)34)8-9-29(23,28(36)40-16-38-19(3)32)24(11-17)14-25(30)21-4-6-22(7-5-21)27(35)39-15-37-18(2)31/h4-9,11,14,20,23-24H,10,12-13,15-16H2,1-3H3,(H,33,34)/b25-14-/t20-,23+,24+,29+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Antagonism of carbachol action on nAChR of isolated frog rectus abdominus.				Eur J Med Chem 148: 26-38 (2018) Article DOI: 10.1016/j.ejmech.2018.01.100 BindingDB Entry DOI: 10.7270/Q2DF6TRW
					More data for this Ligand-Target Pair

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