Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Competitive inhibition of human KDM2A expressed in Escherichia coli using 2-oxoglutarate by enzyme kinetic assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Mixed type inhibition of human KDM2A expressed in Escherichia coli assessed inhibition constant for compound-enzyme-substrate complex using methyl ly... | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271950 (CHEMBL4127821) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271847 (CHEMBL4127736) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271833 (CHEMBL3792857) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271878 (CHEMBL4125829) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271834 (CHEMBL3234727) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271963 (CHEMBL1559342) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50395083 (CHEMBL2164246) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Aeromonas hydrophila) | BDBM50271833 (CHEMBL3792857) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Aeromonas hydrophila CphA using fluorogenic cephalosporin as substrate | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271893 (CHEMBL4128221) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents | PDB Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271889 (CHEMBL4129411) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395083 (CHEMBL2164246) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271952 (CHEMBL4126465) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50247639 (CHEMBL4068716) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395078 (CHEMBL2164245) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50129197 (4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50129197 (4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone lysine demethylase PHF8 (Homo sapiens (Human)) | BDBM50395083 (CHEMBL2164246) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5C (Homo sapiens (Human)) | BDBM50395083 (CHEMBL2164246) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone lysine demethylase PHF8 (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50197063 (4,6-dioxoheptanoic acid | CHEMBL222824 | succinyla...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271891 (CHEMBL4129450) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 1 min using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271835 (CHEMBL4095898) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271824 (CHEMBL4129233) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 10 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 15 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 20 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271798 (CHEMBL3221923) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271868 (CHEMBL4125695) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271867 (CHEMBL4128976) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 6B (Homo sapiens (Human)) | BDBM50129197 (4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM6B catalytic domain expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5C (Homo sapiens (Human)) | BDBM50395078 (CHEMBL2164245) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271836 (CHEMBL4126979) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM2A expressed in Escherichia coli by formaldehyde dehydrogenase coupled assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271876 (CHEMBL4125965) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone lysine demethylase PHF8 (Homo sapiens (Human)) | BDBM50129197 (4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5C (Homo sapiens (Human)) | BDBM50129197 (4-(Hydroxyamino)-4-oxobutanoic acid | CHEMBL51979 ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271800 (CHEMBL4129222) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Aeromonas hydrophila) | BDBM50271835 (CHEMBL4095898) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Aeromonas hydrophila CphA using fluorogenic cephalosporin as substrate | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 7A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human KDM7A catalytic domain expressed in Escherichia coli by MALDI assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM50028968 (CHEMBL3335712) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM50028971 (CHEMBL3335713) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone lysine demethylase PHF8 (Homo sapiens (Human)) | BDBM50197063 (4,6-dioxoheptanoic acid | CHEMBL222824 | succinyla...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase type 2 (Bacillus cereus) | BDBM50271915 (CHEMBL4129039) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assay | Bioorg Med Chem 26: 2928-2936 (2018) Article DOI: 10.1016/j.bmc.2018.02.043 BindingDB Entry DOI: 10.7270/Q2M61NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-butyrobetaine dioxygenase (Homo sapiens (Human)) | BDBM50028972 (Benzene Selenoic Acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Bioorg Med Chem Lett 24: 4954-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.035 BindingDB Entry DOI: 10.7270/Q2D2207X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50365099 (CHEMBL1951197) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay | Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1 | |||||||||||
More data for this Ligand-Target Pair |
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