Compile Data Set for Download or QSAR

Found 37 hits with Last Name = 'salvador' and Initial = 'mk'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50085658 ((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12 |r| Show InChI InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	15.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 90 mins				J Med Chem 55: 7719-35 (2012) Article DOI: 10.1021/jm3007504 BindingDB Entry DOI: 10.7270/Q2H41SK5
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50080550 ((2-Amino-4,5-dimethyl-thiophen-3-yl)-(3-trifluorom...) Show SMILES Cc1sc(N)c(C(=O)c2cccc(c2)C(F)(F)F)c1C Show InChI InChI=1S/C14H12F3NOS/c1-7-8(2)20-13(18)11(7)12(19)9-4-3-5-10(6-9)14(15,16)17/h3-6H,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from A1 adenosine receptor in rat membranes				Bioorg Med Chem 20: 996-1007 (2012) Article DOI: 10.1016/j.bmc.2011.11.044 BindingDB Entry DOI: 10.7270/Q2028S19
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50080550 ((2-Amino-4,5-dimethyl-thiophen-3-yl)-(3-trifluorom...) Show SMILES Cc1sc(N)c(C(=O)c2cccc(c2)C(F)(F)F)c1C Show InChI InChI=1S/C14H12F3NOS/c1-7-8(2)20-13(18)11(7)12(19)9-4-3-5-10(6-9)14(15,16)17/h3-6H,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from adenosine A1 receptor in rat membrane				J Med Chem 55: 7719-35 (2012) Article DOI: 10.1021/jm3007504 BindingDB Entry DOI: 10.7270/Q2H41SK5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528631 (CHEMBL4526719) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]cc1-c1cc2ccccc2s1 Show InChI InChI=1S/C20H18N2O3S/c1-23-15-8-13(9-16(24-2)20(15)25-3)19-14(11-21-22-19)18-10-12-6-4-5-7-17(12)26-18/h4-11H,1-3H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528630 (CHEMBL4440494) Show SMILES COc1ccc(cc1)-c1n[nH]cc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C19H20N2O4/c1-22-14-7-5-12(6-8-14)18-15(11-20-21-18)13-9-16(23-2)19(25-4)17(10-13)24-3/h5-11H,1-4H3,(H,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528642 (CHEMBL4447541) Show SMILES CCOc1ccc(cc1)-c1n[nH]cc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H22N2O4/c1-5-26-15-8-6-13(7-9-15)19-16(12-21-22-19)14-10-17(23-2)20(25-4)18(11-14)24-3/h6-12H,5H2,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528635 (CHEMBL4473254) Show SMILES CCOc1ccc(cc1)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H22N2O4/c1-5-26-15-8-6-13(7-9-15)16-12-21-22-19(16)14-10-17(23-2)20(25-4)18(11-14)24-3/h6-12H,5H2,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528629 (CHEMBL4524533) Show SMILES COc1ccc(cc1)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C19H20N2O4/c1-22-14-7-5-12(6-8-14)15-11-20-21-18(15)13-9-16(23-2)19(25-4)17(10-13)24-3/h5-11H,1-4H3,(H,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528638 (CHEMBL4442113) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]cc1-c1ccc(C)cc1 Show InChI InChI=1S/C19H20N2O3/c1-12-5-7-13(8-6-12)15-11-20-21-18(15)14-9-16(22-2)19(24-4)17(10-14)23-3/h5-11H,1-4H3,(H,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528636 (CHEMBL4464909) Show SMILES CCOc1ccc(cc1Cl)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H21ClN2O4/c1-5-27-16-7-6-12(8-15(16)21)14-11-22-23-19(14)13-9-17(24-2)20(26-4)18(10-13)25-3/h6-11H,5H2,1-4H3,(H,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528641 (CHEMBL4436465) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]cc1-c1ccc2ccccc2c1 Show InChI InChI=1S/C22H20N2O3/c1-25-19-11-17(12-20(26-2)22(19)27-3)21-18(13-23-24-21)16-9-8-14-6-4-5-7-15(14)10-16/h4-13H,1-3H3,(H,23,24)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528633 (CHEMBL4522990) Show SMILES COc1ccc(cc1F)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C19H19FN2O4/c1-23-15-6-5-11(7-14(15)20)13-10-21-22-18(13)12-8-16(24-2)19(26-4)17(9-12)25-3/h5-10H,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528634 (CHEMBL4554434) Show SMILES COc1ccc(cc1C)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H22N2O4/c1-12-8-13(6-7-16(12)23-2)15-11-21-22-19(15)14-9-17(24-3)20(26-5)18(10-14)25-4/h6-11H,1-5H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528640 (CHEMBL4551856) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]cc1-c1ccc(C)c(F)c1 Show InChI InChI=1S/C19H19FN2O3/c1-11-5-6-12(7-15(11)20)14-10-21-22-18(14)13-8-16(23-2)19(25-4)17(9-13)24-3/h5-10H,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528644 (CHEMBL4449830) Show SMILES CCSc1ccc(cc1)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H22N2O3S/c1-5-26-15-8-6-13(7-9-15)16-12-21-22-19(16)14-10-17(23-2)20(25-4)18(11-14)24-3/h6-12H,5H2,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528645 (CHEMBL4451991) Show SMILES COc1ccc(cc1Cl)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C19H19ClN2O4/c1-23-15-6-5-11(7-14(15)20)13-10-21-22-18(13)12-8-16(24-2)19(26-4)17(9-12)25-3/h5-10H,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528639 (CHEMBL4525021) Show SMILES CCc1ccc(cc1)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H22N2O3/c1-5-13-6-8-14(9-7-13)16-12-21-22-19(16)15-10-17(23-2)20(25-4)18(11-15)24-3/h6-12H,5H2,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528643 (CHEMBL4533893) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]cc1-c1ccc(SC)cc1 Show InChI InChI=1S/C19H20N2O3S/c1-22-16-9-13(10-17(23-2)19(16)24-3)18-15(11-20-21-18)12-5-7-14(25-4)8-6-12/h5-11H,1-4H3,(H,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528637 (CHEMBL4541938) Show SMILES COc1cc(cc(OC)c1OC)-c1c[nH]nc1-c1ccc(C)cc1 Show InChI InChI=1S/C19H20N2O3/c1-12-5-7-13(8-6-12)18-15(11-20-21-18)14-9-16(22-2)19(24-4)17(10-14)23-3/h5-11H,1-4H3,(H,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50528632 (CHEMBL4459196) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]cc1-c1ccc(C)c(C)c1 Show InChI InChI=1S/C20H22N2O3/c1-12-6-7-14(8-13(12)2)16-11-21-22-19(16)15-9-17(23-3)20(25-5)18(10-15)24-4/h6-11H,1-5H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051065 (CHEMBL3318073) Show SMILES COc1cc(cc(OC)c1OC)C(=O)n1nc(Nc2ccc(C)cc2)nc1N Show InChI InChI=1S/C19H21N5O4/c1-11-5-7-13(8-6-11)21-19-22-18(20)24(23-19)17(25)12-9-14(26-2)16(28-4)15(10-12)27-3/h5-10H,1-4H3,(H3,20,21,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly after 20 mins incubation by spectrophotometric analysis				J Med Chem 58: 3209-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b00155 BindingDB Entry DOI: 10.7270/Q2QV3P6V
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50084938 (CHEMBL3427378) Show SMILES COC(=O)c1oc2cc(OC)ccc2c1Nc1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H21NO7/c1-23-12-6-7-13-14(10-12)28-19(20(22)27-5)17(13)21-11-8-15(24-2)18(26-4)16(9-11)25-3/h6-10,21H,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly after 20 mins incubation by spectrophotometric analysis				J Med Chem 58: 3209-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b00155 BindingDB Entry DOI: 10.7270/Q2QV3P6V
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051067 (CHEMBL3318075) Show SMILES COc1cc(cc(OC)c1OC)C(=O)n1nc(Nc2ccc(C)c(C)c2)nc1N Show InChI InChI=1S/C20H23N5O4/c1-11-6-7-14(8-12(11)2)22-20-23-19(21)25(24-20)18(26)13-9-15(27-3)17(29-5)16(10-13)28-4/h6-10H,1-5H3,(H3,21,22,23,24)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051068 (CHEMBL3318076) Show SMILES CCc1ccc(Nc2nc(N)n(n2)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1 Show InChI InChI=1S/C20H23N5O4/c1-5-12-6-8-14(9-7-12)22-20-23-19(21)25(24-20)18(26)13-10-15(27-2)17(29-4)16(11-13)28-3/h6-11H,5H2,1-4H3,(H3,21,22,23,24)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50084939 (CHEMBL3427379) Show SMILES CCOC(=O)c1oc2cc(OC)ccc2c1Nc1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C21H23NO7/c1-6-28-21(23)20-18(14-8-7-13(24-2)11-15(14)29-20)22-12-9-16(25-3)19(27-5)17(10-12)26-4/h7-11,22H,6H2,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly after 20 mins incubation by spectrophotometric analysis				J Med Chem 58: 3209-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b00155 BindingDB Entry DOI: 10.7270/Q2QV3P6V
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051066 (CHEMBL3318074) Show SMILES COc1cc(cc(OC)c1OC)C(=O)n1nc(Nc2cccc(C)c2)nc1N Show InChI InChI=1S/C19H21N5O4/c1-11-6-5-7-13(8-11)21-19-22-18(20)24(23-19)17(25)12-9-14(26-2)16(28-4)15(10-12)27-3/h5-10H,1-4H3,(H3,20,21,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051072 (CHEMBL3318084) Show SMILES COc1cc(cc(OC)c1OC)C(=O)n1nc(Nc2ccc3OCOc3c2)nc1N Show InChI InChI=1S/C19H19N5O6/c1-26-14-6-10(7-15(27-2)16(14)28-3)17(25)24-18(20)22-19(23-24)21-11-4-5-12-13(8-11)30-9-29-12/h4-8H,9H2,1-3H3,(H3,20,21,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051071 (CHEMBL3318080) Show SMILES COc1cccc(Nc2nc(N)n(n2)C(=O)c2cc(OC)c(OC)c(OC)c2)c1 Show InChI InChI=1S/C19H21N5O5/c1-26-13-7-5-6-12(10-13)21-19-22-18(20)24(23-19)17(25)11-8-14(27-2)16(29-4)15(9-11)28-3/h5-10H,1-4H3,(H3,20,21,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50215153 (CHEMBL108621) Show SMILES COc1ccc(cc1N)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C19H21N3O4/c1-23-15-6-5-11(7-14(15)20)13-10-21-22-18(13)12-8-16(24-2)19(26-4)17(9-12)25-3/h5-10H,20H2,1-4H3,(H,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization incubated for 15 mins followed by addition of GTP and measured for 20 mins by turbidimetric analysi...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111577 BindingDB Entry DOI: 10.7270/Q2HQ43C6
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051070 (CHEMBL3318079) Show SMILES COc1ccc(Nc2nc(N)n(n2)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1 Show InChI InChI=1S/C19H21N5O5/c1-26-13-7-5-12(6-8-13)21-19-22-18(20)24(23-19)17(25)11-9-14(27-2)16(29-4)15(10-11)28-3/h5-10H,1-4H3,(H3,20,21,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50084941 (CHEMBL3427381) Show SMILES CCOC(=O)c1oc2c(OC)cccc2c1Nc1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C21H23NO7/c1-6-28-21(23)20-17(13-8-7-9-14(24-2)18(13)29-20)22-12-10-15(25-3)19(27-5)16(11-12)26-4/h7-11,22H,6H2,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly after 20 mins incubation by spectrophotometric analysis				J Med Chem 58: 3209-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b00155 BindingDB Entry DOI: 10.7270/Q2QV3P6V
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50084937 (CHEMBL3427376) Show SMILES COC(=O)c1oc2ccc(OC)cc2c1Nc1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H21NO7/c1-23-12-6-7-14-13(10-12)17(19(28-14)20(22)27-5)21-11-8-15(24-2)18(26-4)16(9-11)25-3/h6-10,21H,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly after 20 mins incubation by spectrophotometric analysis				J Med Chem 58: 3209-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b00155 BindingDB Entry DOI: 10.7270/Q2QV3P6V
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50084940 (CHEMBL3427380) Show SMILES COC(=O)c1oc2c(OC)cccc2c1Nc1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H21NO7/c1-23-13-8-6-7-12-16(19(20(22)27-5)28-17(12)13)21-11-9-14(24-2)18(26-4)15(10-11)25-3/h6-10,21H,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin assembly after 20 mins incubation by spectrophotometric analysis				J Med Chem 58: 3209-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b00155 BindingDB Entry DOI: 10.7270/Q2QV3P6V
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50051069 (CHEMBL3318077) Show SMILES COc1cc(cc(OC)c1OC)C(=O)n1nc(Nc2ccc(cc2)C(C)C)nc1N Show InChI InChI=1S/C21H25N5O4/c1-12(2)13-6-8-15(9-7-13)23-21-24-20(22)26(25-21)19(27)14-10-16(28-3)18(30-5)17(11-14)29-4/h6-12H,1-5H3,(H3,22,23,24,25)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by turbidimetry				J Med Chem 57: 6795-808 (2014) Article DOI: 10.1021/jm5008193 BindingDB Entry DOI: 10.7270/Q26111Z5
					More data for this Ligand-Target Pair