Compile Data Set for Download or QSAR

Found 237 hits with Last Name = 'sanderson' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301772 ((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...) Show SMILES C[C@@H]1CNCCN1c1ccc(=O)n(CCOc2ccccc2C(F)(F)F)n1 |r| Show InChI InChI=1S/C18H21F3N4O2/c1-13-12-22-8-9-24(13)16-6-7-17(26)25(23-16)10-11-27-15-5-3-2-4-14(15)18(19,20)21/h2-7,13,22H,8-12H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA				Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50302145 ((R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpipera...) Show SMILES C[C@@H]1CNCCN1c1ccc(=O)n(CCOc2ccccc2Cl)n1 |r| Show InChI InChI=1S/C17H21ClN4O2/c1-13-12-19-8-9-21(13)16-6-7-17(23)22(20-16)10-11-24-15-5-3-2-4-14(15)18/h2-7,13,19H,8-12H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	325	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA				Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50302160 (6-(piperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenox...) Show SMILES FC(F)(F)c1ccccc1OCCn1nc(ccc1=O)N1CCNCC1 Show InChI InChI=1S/C17H19F3N4O2/c18-17(19,20)13-3-1-2-4-14(13)26-12-11-24-16(25)6-5-15(22-24)23-9-7-21-8-10-23/h1-6,21H,7-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	424	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA				Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50302151 ((S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazi...) Show SMILES C[C@@H](COc1ccccc1Cl)n1nc(ccc1=O)N1CCNCC1 |r| Show InChI InChI=1S/C17H21ClN4O2/c1-13(12-24-15-5-3-2-4-14(15)18)22-17(23)7-6-16(20-22)21-10-8-19-9-11-21/h2-7,13,19H,8-12H2,1H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	728	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA				Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50226008 ((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...) Show SMILES CCCN1CCO[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO2/c1-2-6-14-7-8-16-13(10-14)11-4-3-5-12(15)9-11/h3-5,9,13,15H,2,6-8,10H2,1H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Binding affinity to rat 5HT2A receptor				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50226008 ((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...) Show SMILES CCCN1CCO[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO2/c1-2-6-14-7-8-16-13(10-14)11-4-3-5-12(15)9-11/h3-5,9,13,15H,2,6-8,10H2,1H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Binding affinity to rat alpha1A adrenergic receptor				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50226008 ((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...) Show SMILES CCCN1CCO[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO2/c1-2-6-14-7-8-16-13(10-14)11-4-3-5-12(15)9-11/h3-5,9,13,15H,2,6-8,10H2,1H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Binding affinity to human alpha2A adrenergic receptor				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50226008 ((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...) Show SMILES CCCN1CCO[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO2/c1-2-6-14-7-8-16-13(10-14)11-4-3-5-12(15)9-11/h3-5,9,13,15H,2,6-8,10H2,1H3/t13-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M1 receptor				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50302141 (2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...) Show SMILES Clc1ccccc1OCCn1nc(ccc1=O)N1CCNCC1 Show InChI InChI=1S/C16H19ClN4O2/c17-13-3-1-2-4-14(13)23-12-11-21-16(22)6-5-15(19-21)20-9-7-18-8-10-20/h1-6,18H,7-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA				Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50226008 ((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...) Show SMILES CCCN1CCO[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO2/c1-2-6-14-7-8-16-13(10-14)11-4-3-5-12(15)9-11/h3-5,9,13,15H,2,6-8,10H2,1H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Binding affinity to human histamine H1 receptor				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50226008 ((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...) Show SMILES CCCN1CCO[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO2/c1-2-6-14-7-8-16-13(10-14)11-4-3-5-12(15)9-11/h3-5,9,13,15H,2,6-8,10H2,1H3/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Displacement of dofetilide from hERG				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50197517 ((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of rat NEP				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50197517 ((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of rabbit NEP				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197517 ((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.0	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197513 ((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O Show InChI InChI=1S/C22H31NO5/c1-28-11-8-18(19(25)26)12-21(9-4-5-10-21)20(27)23-22(15-24)13-16-6-2-3-7-17(16)14-22/h2-3,6-7,18,24H,4-5,8-15H2,1H3,(H,23,27)(H,25,26)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	7.0	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197519 ((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C21H30FNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.0	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197517 ((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant NEP				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197507 ((S)-4-methoxy-2-{1-[(1R,2S)-2-(4-methoxy-phenyl)-c...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)N[C@@H]1C[C@H]1c1ccc(OC)cc1)C(O)=O Show InChI InChI=1S/C22H31NO5/c1-27-12-9-16(20(24)25)14-22(10-3-4-11-22)21(26)23-19-13-18(19)15-5-7-17(28-2)8-6-15/h5-8,16,18-19H,3-4,9-14H2,1-2H3,(H,23,26)(H,24,25)/t16-,18+,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	7.0	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197513 ((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O Show InChI InChI=1S/C22H31NO5/c1-28-11-8-18(19(25)26)12-21(9-4-5-10-21)20(27)23-22(15-24)13-16-6-2-3-7-17(16)14-22/h2-3,6-7,18,24H,4-5,8-15H2,1H3,(H,23,27)(H,25,26)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7.4				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of rabbit NEP				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of rabbit NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197517 ((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.5	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7.4				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190771 ((R)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O Show InChI InChI=1S/C22H31NO4/c1-2-7-18(19(25)26)12-21(10-5-6-11-21)20(27)23-22(15-24)13-16-8-3-4-9-17(16)14-22/h3-4,8-9,18,24H,2,5-7,10-15H2,1H3,(H,23,27)(H,25,26)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197519 ((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C21H30FNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7.4				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50197507 ((S)-4-methoxy-2-{1-[(1R,2S)-2-(4-methoxy-phenyl)-c...) Show SMILES COCC[C@H](CC1(CCCC1)C(=O)N[C@@H]1C[C@H]1c1ccc(OC)cc1)C(O)=O Show InChI InChI=1S/C22H31NO5/c1-27-12-9-16(20(24)25)14-22(10-3-4-11-22)21(26)23-19-13-18(19)15-5-7-17(28-2)8-6-15/h5-8,16,18-19H,3-4,9-14H2,1-2H3,(H,23,26)(H,24,25)/t16-,18+,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.8	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7.4				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of rat NEP				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of rat NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18.9	n/a	n/a	n/a	n/a	7.0	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant NEP				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190753 (2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(Cc2ccccc2)s1)C(O)=O Show InChI InChI=1S/C21H27N3O3S/c1-2-8-16(18(25)26)14-21(11-6-7-12-21)19(27)22-20-24-23-17(28-20)13-15-9-4-3-5-10-15/h3-5,9-10,16H,2,6-8,11-14H2,1H3,(H,25,26)(H,22,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190746 ((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31.8	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human kidney NEP at pH 7.4				Bioorg Med Chem 15: 142-59 (2006) Article DOI: 10.1016/j.bmc.2006.10.002 BindingDB Entry DOI: 10.7270/Q2ZS2W4J
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190762 (2-((1-((5-(cyclopropylmethyl)-1,3,4-thiadiazol-2-y...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC2CC2)s1)C(O)=O Show InChI InChI=1S/C18H27N3O3S/c1-2-5-13(15(22)23)11-18(8-3-4-9-18)16(24)19-17-21-20-14(25-17)10-12-6-7-12/h12-13H,2-11H2,1H3,(H,22,23)(H,19,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190737 (2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...) Show SMILES CCc1nnc(NC(=O)C2(CC(CCc3ccccc3)C(O)=O)CCCC2)s1 Show InChI InChI=1S/C21H27N3O3S/c1-2-17-23-24-20(28-17)22-19(27)21(12-6-7-13-21)14-16(18(25)26)11-10-15-8-4-3-5-9-15/h3-5,8-9,16H,2,6-7,10-14H2,1H3,(H,25,26)(H,22,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190773 (2-[1-(5-ethyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-cyc...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190752 (2-((1-((1-ethyl-1H-1,2,3-triazol-4-yl)carbamoyl)cy...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1cn(CC)nn1)C(O)=O Show InChI InChI=1S/C16H26N4O3/c1-3-7-12(14(21)22)10-16(8-5-6-9-16)15(23)17-13-11-20(4-2)19-18-13/h11-12H,3-10H2,1-2H3,(H,17,23)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190764 (2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...) Show SMILES CCCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C17H27N3O3S/c1-3-5-8-12(14(21)22)11-17(9-6-7-10-17)15(23)18-16-20-19-13(4-2)24-16/h12H,3-11H2,1-2H3,(H,21,22)(H,18,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190750 (2-((1-((4-benzylpyridin-2-yl)carbamoyl)cyclopentyl...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1cc(Cc2ccccc2)ccn1)C(O)=O Show InChI InChI=1S/C24H30N2O3/c1-2-8-20(22(27)28)17-24(12-6-7-13-24)23(29)26-21-16-19(11-14-25-21)15-18-9-4-3-5-10-18/h3-5,9-11,14,16,20H,2,6-8,12-13,15,17H2,1H3,(H,27,28)(H,25,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190769 (CHEMBL377037 | rac-2-((1-((2-(hydroxymethyl)-2,3-d...) Show SMILES CCCC(CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O Show InChI InChI=1S/C22H31NO4/c1-2-7-18(19(25)26)12-21(10-5-6-11-21)20(27)23-22(15-24)13-16-8-3-4-9-17(16)14-22/h3-4,8-9,18,24H,2,5-7,10-15H2,1H3,(H,23,27)(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190739 ((R)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...) Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O Show InChI InChI=1S/C15H23N3O3S/c1-3-6-11(12(19)20)9-15(7-4-5-8-15)13(21)16-14-18-17-10(2)22-14/h11H,3-9H2,1-2H3,(H,19,20)(H,16,18,21)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190738 (2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...) Show SMILES CCc1nnc(NC(=O)C2(CC(CCC(C)C)C(O)=O)CCCC2)s1 Show InChI InChI=1S/C18H29N3O3S/c1-4-14-20-21-17(25-14)19-16(24)18(9-5-6-10-18)11-13(15(22)23)8-7-12(2)3/h12-13H,4-11H2,1-3H3,(H,22,23)(H,19,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190758 (2-((1-((5-isobutyl-1,3,4-thiadiazol-2-yl)carbamoyl...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC(C)C)s1)C(O)=O Show InChI InChI=1S/C18H29N3O3S/c1-4-7-13(15(22)23)11-18(8-5-6-9-18)16(24)19-17-21-20-14(25-17)10-12(2)3/h12-13H,4-11H2,1-3H3,(H,22,23)(H,19,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190757 (CHEMBL439508 | cis-2-((1-((4-carbamoylcyclohexyl)c...) Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(N)=O)C(O)=O |wU:13.13,16.20,(-5.69,-23.39,;-5.69,-24.93,;-4.36,-25.7,;-4.36,-27.24,;-3.03,-28.01,;-1.69,-27.24,;-2.94,-26.34,;-2.46,-24.87,;-.92,-24.87,;-.45,-26.34,;-.36,-28.01,;-.36,-29.55,;.97,-27.24,;2.31,-28.01,;3.63,-27.24,;4.97,-28.02,;4.96,-29.56,;3.62,-30.32,;2.3,-29.55,;6.29,-30.33,;7.63,-29.57,;6.29,-31.87,;-5.69,-28.01,;-7.03,-27.24,;-5.69,-29.55,)| Show InChI InChI=1S/C19H32N2O4/c1-2-5-14(17(23)24)12-19(10-3-4-11-19)18(25)21-15-8-6-13(7-9-15)16(20)22/h13-15H,2-12H2,1H3,(H2,20,22)(H,21,25)(H,23,24)/t13-,14?,15+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190761 (CHEMBL209493 | rac-2-((1-((5-methyl-1,3,4-thiadiaz...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O Show InChI InChI=1S/C15H23N3O3S/c1-3-6-11(12(19)20)9-15(7-4-5-8-15)13(21)16-14-18-17-10(2)22-14/h11H,3-9H2,1-2H3,(H,19,20)(H,16,18,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190780 (2-((1-((4-butylpyridin-2-yl)carbamoyl)cyclopentyl)...) Show SMILES CCCCc1ccnc(NC(=O)C2(CC(CCC)C(O)=O)CCCC2)c1 Show InChI InChI=1S/C21H32N2O3/c1-3-5-9-16-10-13-22-18(14-16)23-20(26)21(11-6-7-12-21)15-17(8-4-2)19(24)25/h10,13-14,17H,3-9,11-12,15H2,1-2H3,(H,24,25)(H,22,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190777 (2-((1-(((1R,2R)-2-benzylcyclohexyl)carbamoyl)cyclo...) Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@@H]1CCCC[C@@H]1Cc1ccccc1)C(O)=O Show InChI InChI=1S/C25H37NO3/c1-2-10-21(23(27)28)18-25(15-8-9-16-25)24(29)26-22-14-7-6-13-20(22)17-19-11-4-3-5-12-19/h3-5,11-12,20-22H,2,6-10,13-18H2,1H3,(H,26,29)(H,27,28)/t20-,21?,22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190743 ((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...) Show SMILES CCC[C@@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O Show InChI InChI=1S/C22H31NO4/c1-2-7-18(19(25)26)12-21(10-5-6-11-21)20(27)23-22(15-24)13-16-8-3-4-9-17(16)14-22/h3-4,8-9,18,24H,2,5-7,10-15H2,1H3,(H,23,27)(H,25,26)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190782 (2-((1-(((1R,3S)-3-carbamoylcyclopentyl)carbamoyl)c...) Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@@H]1CC[C@@H](C1)C(N)=O)C(O)=O Show InChI InChI=1S/C18H30N2O4/c1-2-5-13(16(22)23)11-18(8-3-4-9-18)17(24)20-14-7-6-12(10-14)15(19)21/h12-14H,2-11H2,1H3,(H2,19,21)(H,20,24)(H,22,23)/t12-,13?,14+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair

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