Compile Data Set for Download or QSAR

Found 899 hits with Last Name = 'sarafianos' and Initial = 'sg'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468807 (CHEMBL4276679) Show SMILES COc1ccc(cc1OC)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C18H16N2O5S/c1-24-14-8-5-12(9-15(14)25-2)11-3-6-13(7-4-11)26-16-10-17(21)20(23)18(22)19-16/h3-10,23H,1-2H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468795 (CHEMBL4292982) Show SMILES Oc1ccc(cc1)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H12N2O4S/c19-12-5-1-10(2-6-12)11-3-7-13(8-4-11)23-14-9-15(20)18(22)16(21)17-14/h1-9,19,22H,(H,17,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468812 (CHEMBL4278348) Show SMILES COc1ccc(cc1F)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H13FN2O4S/c1-24-14-7-4-11(8-13(14)18)10-2-5-12(6-3-10)25-15-9-16(21)20(23)17(22)19-15/h2-9,23H,1H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468798 (CHEMBL4288585) Show SMILES On1c(=O)cc(Sc2cccc(c2)-c2ccc(F)c(Cl)c2)[nH]c1=O Show InChI InChI=1S/C16H10ClFN2O3S/c17-12-7-10(4-5-13(12)18)9-2-1-3-11(6-9)24-14-8-15(21)20(23)16(22)19-14/h1-8,23H,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468766 (CHEMBL4277935) Show SMILES On1c(=O)cc(Sc2cccc(c2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H11ClN2O3S/c17-12-6-4-10(5-7-12)11-2-1-3-13(8-11)23-14-9-15(20)19(22)16(21)18-14/h1-9,22H,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468774 (CHEMBL4286262) Show SMILES Cc1cc(ccc1F)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H13FN2O3S/c1-10-8-12(4-7-14(10)18)11-2-5-13(6-3-11)24-15-9-16(21)20(23)17(22)19-15/h2-9,23H,1H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468788 (CHEMBL4289601) Show SMILES On1c(=O)cc(Sc2ccc(cc2)-c2cccc(F)c2)[nH]c1=O Show InChI InChI=1S/C16H11FN2O3S/c17-12-3-1-2-11(8-12)10-4-6-13(7-5-10)23-14-9-15(20)19(22)16(21)18-14/h1-9,22H,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468793 (CHEMBL4293068) Show SMILES On1c(=O)cc(Sc2cccc(c2)-c2ccc(F)cc2)[nH]c1=O Show InChI InChI=1S/C16H11FN2O3S/c17-12-6-4-10(5-7-12)11-2-1-3-13(8-11)23-14-9-15(20)19(22)16(21)18-14/h1-9,22H,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468767 (CHEMBL4277847) Show SMILES COc1cccc(c1)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H14N2O4S/c1-23-13-4-2-3-12(9-13)11-5-7-14(8-6-11)24-15-10-16(20)19(22)17(21)18-15/h2-10,22H,1H3,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468808 (CHEMBL4293481) Show SMILES COc1cc(OC)cc(c1)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C18H16N2O5S/c1-24-13-7-12(8-14(9-13)25-2)11-3-5-15(6-4-11)26-16-10-17(21)20(23)18(22)19-16/h3-10,23H,1-2H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468809 (CHEMBL4285242) Show SMILES On1c(=O)cc(Sc2cccc(c2)-c2cccc(F)c2)[nH]c1=O Show InChI InChI=1S/C16H11FN2O3S/c17-12-5-1-3-10(7-12)11-4-2-6-13(8-11)23-14-9-15(20)19(22)16(21)18-14/h1-9,22H,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468805 (CHEMBL4282781) Show SMILES Cc1ccc(cc1)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H14N2O3S/c1-11-2-4-12(5-3-11)13-6-8-14(9-7-13)23-15-10-16(20)19(22)17(21)18-15/h2-10,22H,1H3,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468791 (CHEMBL4278928) Show SMILES On1c(=O)cc(Sc2ccc(cc2)-c2ccc(F)cc2)[nH]c1=O Show InChI InChI=1S/C16H11FN2O3S/c17-12-5-1-10(2-6-12)11-3-7-13(8-4-11)23-14-9-15(20)19(22)16(21)18-14/h1-9,22H,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468781 (CHEMBL4285791) Show SMILES COc1ccc(cc1)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H14N2O4S/c1-23-13-6-2-11(3-7-13)12-4-8-14(9-5-12)24-15-10-16(20)19(22)17(21)18-15/h2-10,22H,1H3,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468782 (CHEMBL4289681) Show SMILES On1c(=O)cc(Sc2cccc(c2)-c2ccc(cc2)C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C17H11F3N2O3S/c18-17(19,20)12-6-4-10(5-7-12)11-2-1-3-13(8-11)26-14-9-15(23)22(25)16(24)21-14/h1-9,25H,(H,21,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468773 (CHEMBL4282386) Show SMILES On1c(=O)cc(Sc2ccc(cc2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H11ClN2O3S/c17-12-5-1-10(2-6-12)11-3-7-13(8-4-11)23-14-9-15(20)19(22)16(21)18-14/h1-9,22H,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468775 (CHEMBL4281804) Show SMILES On1c(=O)cc(Sc2cccc(c2)-c2cccc(c2)C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C17H11F3N2O3S/c18-17(19,20)12-5-1-3-10(7-12)11-4-2-6-13(8-11)26-14-9-15(23)22(25)16(24)21-14/h1-9,25H,(H,21,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468772 (CHEMBL4294846) Show SMILES On1c(=O)cc(Sc2cccc3ccccc23)[nH]c1=O Show InChI InChI=1S/C14H10N2O3S/c17-13-8-12(15-14(18)16(13)19)20-11-7-3-5-9-4-1-2-6-10(9)11/h1-8,19H,(H,15,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468821 (CHEMBL4285516) Show SMILES COc1ccc(cc1F)-c1ccc(Cc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C18H15FN2O4/c1-25-16-7-6-13(9-15(16)19)12-4-2-11(3-5-12)8-14-10-17(22)21(24)18(23)20-14/h2-7,9-10,24H,8H2,1H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468815 (CHEMBL4283283) Show SMILES COc1ccc(cc1F)-c1cccc(Cc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H15FN2O4/c1-25-16-6-5-13(9-15(16)19)12-4-2-3-11(7-12)8-14-10-17(22)21(24)18(23)20-14/h2-7,9-10,24H,8H2,1H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468778 (CHEMBL4277795) Show SMILES On1c(=O)cc(Sc2ccccc2Br)[nH]c1=O Show InChI InChI=1S/C10H7BrN2O3S/c11-6-3-1-2-4-7(6)17-8-5-9(14)13(16)10(15)12-8/h1-5,16H,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468780 (CHEMBL4286171) Show SMILES On1c(=O)cc(Sc2ccc(cc2)-c2cccc(c2)C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C17H11F3N2O3S/c18-17(19,20)12-3-1-2-11(8-12)10-4-6-13(7-5-10)26-14-9-15(23)22(25)16(24)21-14/h1-9,25H,(H,21,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468842 (CHEMBL4291139) Show SMILES Cc1cc(ccc1F)-c1cccc(Cc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H15FN2O3/c1-11-7-14(5-6-16(11)19)13-4-2-3-12(8-13)9-15-10-17(22)21(24)18(23)20-15/h2-8,10,24H,9H2,1H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468817 (CHEMBL4294172) Show SMILES On1c(=O)cc(Cc2ccc(cc2)-c2ccc(Cl)cc2Cl)[nH]c1=O Show InChI InChI=1S/C17H12Cl2N2O3/c18-12-5-6-14(15(19)8-12)11-3-1-10(2-4-11)7-13-9-16(22)21(24)17(23)20-13/h1-6,8-9,24H,7H2,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468844 (CHEMBL4280134) Show SMILES On1c(=O)cc(Cc2ccc(cc2)-c2ccc(Cl)c(F)c2)[nH]c1=O Show InChI InChI=1S/C17H12ClFN2O3/c18-14-6-5-12(8-15(14)19)11-3-1-10(2-4-11)7-13-9-16(22)21(24)17(23)20-13/h1-6,8-9,24H,7H2,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50536063 (CHEMBL4580966) Show SMILES CCNc1[nH]c(=O)n(O)c(=O)c1C(=O)NCc1ccc(F)cc1F Show InChI InChI=1S/C14H14F2N4O4/c1-2-17-11-10(13(22)20(24)14(23)19-11)12(21)18-6-7-3-4-8(15)5-9(7)16/h3-5,17,24H,2,6H2,1H3,(H,18,21)(H,19,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length HIV1 reverse transcriptase using RNA-DNA duplex HTS-1 substrate				J Med Chem 59: 6136-48 (2016) Article DOI: 10.1021/acs.jmedchem.6b00040 BindingDB Entry DOI: 10.7270/Q24T6NVG
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468789 (CHEMBL4288722) Show SMILES CCc1ccccc1Sc1cc(=O)n(O)c(=O)[nH]1 Show InChI InChI=1S/C12H12N2O3S/c1-2-8-5-3-4-6-9(8)18-10-7-11(15)14(17)12(16)13-10/h3-7,17H,2H2,1H3,(H,13,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468801 (CHEMBL4284247) Show SMILES CCc1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C12H12N2O3S/c1-2-8-3-5-9(6-4-8)18-10-7-11(15)14(17)12(16)13-10/h3-7,17H,2H2,1H3,(H,13,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468784 (CHEMBL4281242) Show SMILES On1c(=O)cc(Sc2ccc(Br)cc2)[nH]c1=O Show InChI InChI=1S/C10H7BrN2O3S/c11-6-1-3-7(4-2-6)17-8-5-9(14)13(16)10(15)12-8/h1-5,16H,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50536079 (CHEMBL4560700) Show SMILES CCNc1[nH]c(=O)n(O)c(=O)c1C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C14H15FN4O4/c1-2-16-11-10(13(21)19(23)14(22)18-11)12(20)17-7-8-3-5-9(15)6-4-8/h3-6,16,23H,2,7H2,1H3,(H,17,20)(H,18,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length HIV1 reverse transcriptase using RNA-DNA duplex HTS-1 substrate				J Med Chem 59: 6136-48 (2016) Article DOI: 10.1021/acs.jmedchem.6b00040 BindingDB Entry DOI: 10.7270/Q24T6NVG
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468834 (CHEMBL4277572) Show SMILES Cc1cc(ccc1F)-c1ccc(Cc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C18H15FN2O3/c1-11-8-14(6-7-16(11)19)13-4-2-12(3-5-13)9-15-10-17(22)21(24)18(23)20-15/h2-8,10,24H,9H2,1H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468803 (CHEMBL4288444) Show SMILES On1c(=O)cc(Sc2cccc(Br)c2)[nH]c1=O Show InChI InChI=1S/C10H7BrN2O3S/c11-6-2-1-3-7(4-6)17-8-5-9(14)13(16)10(15)12-8/h1-5,16H,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468771 (CHEMBL4288035) Show SMILES Oc1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C10H8N2O4S/c13-6-1-3-7(4-2-6)17-8-5-9(14)12(16)10(15)11-8/h1-5,13,16H,(H,11,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468797 (CHEMBL4291865) Show SMILES On1c(=O)cc(Sc2cccc(Cl)c2)[nH]c1=O Show InChI InChI=1S/C10H7ClN2O3S/c11-6-2-1-3-7(4-6)17-8-5-9(14)13(16)10(15)12-8/h1-5,16H,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468838 (CHEMBL4277884) Show SMILES On1c(=O)cc(Cc2ccc(Br)cc2)[nH]c1=O Show InChI InChI=1S/C11H9BrN2O3/c12-8-3-1-7(2-4-8)5-9-6-10(15)14(17)11(16)13-9/h1-4,6,17H,5H2,(H,13,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468799 (CHEMBL4281980) Show SMILES On1c(=O)cc(Sc2ccccc2-c2ccc(F)cc2)[nH]c1=O Show InChI InChI=1S/C16H11FN2O3S/c17-11-7-5-10(6-8-11)12-3-1-2-4-13(12)23-14-9-15(20)19(22)16(21)18-14/h1-9,22H,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468843 (CHEMBL4284329) Show SMILES On1c(=O)cc(Cc2cccc(c2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C17H13ClN2O3/c18-14-6-4-12(5-7-14)13-3-1-2-11(8-13)9-15-10-16(21)20(23)17(22)19-15/h1-8,10,23H,9H2,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468811 (CHEMBL4280139) Show SMILES On1c(=O)cc(Sc2ccc(cc2)[N+]([O-])=O)[nH]c1=O Show InChI InChI=1S/C10H7N3O5S/c14-9-5-8(11-10(15)12(9)16)19-7-3-1-6(2-4-7)13(17)18/h1-5,16H,(H,11,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468786 (CHEMBL4277423) Show SMILES On1c(=O)cc(Sc2ccccc2C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C11H7F3N2O3S/c12-11(13,14)6-3-1-2-4-7(6)20-8-5-9(17)16(19)10(18)15-8/h1-5,19H,(H,15,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468794 (CHEMBL4276707) Show SMILES COc1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C11H10N2O4S/c1-17-7-2-4-8(5-3-7)18-9-6-10(14)13(16)11(15)12-9/h2-6,16H,1H3,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468770 (CHEMBL4289142) Show SMILES On1c(=O)cc(Sc2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C10H7ClN2O3S/c11-6-1-3-7(4-2-6)17-8-5-9(14)13(16)10(15)12-8/h1-5,16H,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468824 (CHEMBL4285821) Show SMILES On1c(=O)cc(Cc2cccc(Br)c2)[nH]c1=O Show InChI InChI=1S/C11H9BrN2O3/c12-8-3-1-2-7(4-8)5-9-6-10(15)14(17)11(16)13-9/h1-4,6,17H,5H2,(H,13,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468804 (CHEMBL4284648) Show SMILES COc1cccc(Sc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C11H10N2O4S/c1-17-7-3-2-4-8(5-7)18-9-6-10(14)13(16)11(15)12-9/h2-6,16H,1H3,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468810 (CHEMBL4291548) Show SMILES On1c(=O)cc(Sc2cccc(c2)C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C11H7F3N2O3S/c12-11(13,14)6-2-1-3-7(4-6)20-8-5-9(17)16(19)10(18)15-8/h1-5,19H,(H,15,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468785 (CHEMBL4292590) Show SMILES On1c(=O)cc(Sc2ccccc2-c2ccc(cc2)C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C17H11F3N2O3S/c18-17(19,20)11-7-5-10(6-8-11)12-3-1-2-4-13(12)26-14-9-15(23)22(25)16(24)21-14/h1-9,25H,(H,21,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468802 (CHEMBL4279266) Show SMILES On1c(=O)cc(Sc2cccc(F)c2)[nH]c1=O Show InChI InChI=1S/C10H7FN2O3S/c11-6-2-1-3-7(4-6)17-8-5-9(14)13(16)10(15)12-8/h1-5,16H,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50526166 (CHEMBL4446400) Show SMILES COC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)c1cc(=O)n(O)c(=O)[nH]1 Show InChI InChI=1S/C19H14N2O6/c1-27-18(24)14-8-4-12(5-9-14)11-2-6-13(7-3-11)17(23)15-10-16(22)21(26)19(25)20-15/h2-10,26H,1H3,(H,20,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS-1				Eur J Med Chem 166: 390-399 (2019) Article DOI: 10.1016/j.ejmech.2019.01.081 BindingDB Entry DOI: 10.7270/Q2FJ2M7H
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468777 (CHEMBL4278477) Show SMILES On1c(=O)cc(Sc2ccccc2F)[nH]c1=O Show InChI InChI=1S/C10H7FN2O3S/c11-6-3-1-2-4-7(6)17-8-5-9(14)13(16)10(15)12-8/h1-5,16H,(H,12,15)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrate				Eur J Med Chem 156: 652-665 (2018) Article DOI: 10.1016/j.ejmech.2018.07.039 BindingDB Entry DOI: 10.7270/Q20C4ZFB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468822 (CHEMBL4283583) Show SMILES On1c(=O)cc(Cc2ccc(cc2)-c2ccc(F)cc2F)[nH]c1=O Show InChI InChI=1S/C17H12F2N2O3/c18-12-5-6-14(15(19)8-12)11-3-1-10(2-4-11)7-13-9-16(22)21(24)17(23)20-13/h1-6,8-9,24H,7H2,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468826 (CHEMBL4290770) Show SMILES On1c(=O)cc(Cc2ccc(cc2)-c2cc(Cl)cc(c2)C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C18H12ClF3N2O3/c19-14-7-12(6-13(8-14)18(20,21)22)11-3-1-10(2-4-11)5-15-9-16(25)24(27)17(26)23-15/h1-4,6-9,27H,5H2,(H,23,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrate				Eur J Med Chem 156: 680-691 (2018) Article DOI: 10.1016/j.ejmech.2018.07.035 BindingDB Entry DOI: 10.7270/Q2VM4FZ1
					More data for this Ligand-Target Pair

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