Compile Data Set for Download or QSAR

Found 4344 hits with Last Name = 'sato' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (GUINEA PIG)	BDBM50084033 (1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-pheny...) Show SMILES Fc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8| Show InChI InChI=1S/C26H19FN4O2/c27-19-10-3-2-8-17(19)22-18-9-5-7-15-12-13-31(23(15)18)26(33)24(29-22)30-25(32)21-14-16-6-1-4-11-20(16)28-21/h1-11,14,24,28H,12-13H2,(H,30,32)/t24-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 571-5 (1994) BindingDB Entry DOI: 10.7270/Q2WQ029S
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES CC(C)(C)c1ccc(SCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H20N2S/c1-15(2,3)12-4-6-14(7-5-12)18-9-8-13-10-16-11-17-13/h4-7,10-11H,8-9H2,1-3H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (GUINEA PIG)	BDBM21147 ((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 571-5 (1994) BindingDB Entry DOI: 10.7270/Q2WQ029S
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22542 (4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...) Show SMILES C(C1CCNCC1)c1cnc[nH]1 Show InChI InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22542 (4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...) Show SMILES C(C1CCNCC1)c1cnc[nH]1 Show InChI InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (RAT)	BDBM50084033 (1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-pheny...) Show SMILES Fc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8| Show InChI InChI=1S/C26H19FN4O2/c27-19-10-3-2-8-17(19)22-18-9-5-7-15-12-13-31(23(15)18)26(33)24(29-22)30-25(32)21-14-16-6-1-4-11-20(16)28-21/h1-11,14,24,28H,12-13H2,(H,30,32)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 571-5 (1994) BindingDB Entry DOI: 10.7270/Q2WQ029S
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES CC(C)(C)c1ccc(SCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H20N2S/c1-15(2,3)12-4-6-14(7-5-12)18-9-8-13-10-16-11-17-13/h4-7,10-11H,8-9H2,1-3H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES CC(C)(C)c1ccc(SCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H20N2S/c1-15(2,3)12-4-6-14(7-5-12)18-9-8-13-10-16-11-17-13/h4-7,10-11H,8-9H2,1-3H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50449636 (BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...) Show SMILES [H][C@]12CCC[C@]([H])(C[C@H](C1)NC(=O)c1nn(C)c3ccccc13)N2C |r,TLB:24:23:8.9.7:2.4.3| Show InChI InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)/t12-,13-,14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Center Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor was determined by measuring displacement of [3H]GR-65630 from rat brain cortices				J Med Chem 41: 3015-21 (1998) Article DOI: 10.1021/jm9801004 BindingDB Entry DOI: 10.7270/Q20P10Q9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22904 ((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...) Show SMILES C[C@@H](N)Cc1cnc[nH]1 |r| Show InChI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22911 (2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...) Show SMILES NC(=N)SCCc1cnc[nH]1 Show InChI InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (GUINEA PIG)	BDBM21147 ((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 571-5 (1994) BindingDB Entry DOI: 10.7270/Q2WQ029S
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22910 (4-(1H-imidazol-5-ylmethyl)pyridine | Immethridine) Show SMILES C(c1cnc[nH]1)c1ccncc1 Show InChI InChI=1S/C9H9N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h1-4,6-7H,5H2,(H,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	0.770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317868 (4-(2-(4-tert-Butylphenylamino)ethyl)-1H-imidazole ...) Show SMILES CC(C)(C)c1ccc(NCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H21N3/c1-15(2,3)12-4-6-13(7-5-12)17-9-8-14-10-16-11-18-14/h4-7,10-11,17H,8-9H2,1-3H3,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321823 (4-((1H-Imidazol-4-yl)methyl)-1-(3-(trifluoromethyl...) Show SMILES FC(F)(F)c1cccc(c1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H18F3N3/c17-16(18,19)13-2-1-3-15(9-13)22-6-4-12(5-7-22)8-14-10-20-11-21-14/h1-3,9-12H,4-8H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321813 (4-((1H-Imidazol-4-yl)methyl)-1-(3-isopropylphenyl)...) Show SMILES CC(C)c1cccc(c1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H25N3/c1-14(2)16-4-3-5-18(11-16)21-8-6-15(7-9-21)10-17-12-19-13-20-17/h3-5,11-15H,6-10H2,1-2H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50066000 (5-Chloro-7-methyl-2-(4-methyl-[1,4]diazepan-1-yl)-...) Show SMILES CN1CCCN(CC1)c1nc2cc(Cl)cc(C)c2o1 Show InChI InChI=1S/C14H18ClN3O/c1-10-8-11(15)9-12-13(10)19-14(16-12)18-5-3-4-17(2)6-7-18/h8-9H,3-7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Center Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor was determined by measuring displacement of [3H]GR-65630 from rat brain cortices				J Med Chem 41: 3015-21 (1998) Article DOI: 10.1021/jm9801004 BindingDB Entry DOI: 10.7270/Q20P10Q9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317864 (4-(2-(4-Trifluoromethylphenylamino)ethyl)-1H-imida...) Show SMILES FC(F)(F)c1ccc(SCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H11F3N2S/c13-12(14,15)9-1-3-11(4-2-9)18-6-5-10-7-16-8-17-10/h1-4,7-8H,5-6H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES CC(C)(C)c1ccc(SCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H20N2S/c1-15(2,3)12-4-6-14(7-5-12)18-9-8-13-10-16-11-17-13/h4-7,10-11H,8-9H2,1-3H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant histamine H4 receptor expressed in CHO cells				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES CC(C)(C)c1ccc(SCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H20N2S/c1-15(2,3)12-4-6-14(7-5-12)18-9-8-13-10-16-11-17-13/h4-7,10-11H,8-9H2,1-3H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321827 (4-(4-((1H-Imidazol-4-yl)methyl)piperidin-1-yl)-N,N...) Show SMILES CN(C)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C17H24N4/c1-20(2)16-3-5-17(6-4-16)21-9-7-14(8-10-21)11-15-12-18-13-19-15/h3-6,12-14H,7-11H2,1-2H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321826 (4-(4-((1H-Imidazol-4-yl)methyl)piperidin-1-yl)-N-m...) Show SMILES CNc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H22N4/c1-17-14-2-4-16(5-3-14)20-8-6-13(7-9-20)10-15-11-18-12-19-15/h2-5,11-13,17H,6-10H2,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321815 (4-((1H-Imidazol-4-yl)methyl)-1-(4-(trifluoromethyl...) Show SMILES FC(F)(F)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H18F3N3/c17-16(18,19)13-1-3-15(4-2-13)22-7-5-12(6-8-22)9-14-10-20-11-21-14/h1-4,10-12H,5-9H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317867 (4-(2-(3-tert-Butylphenylamino)ethyl)-1H-imidazole ...) Show SMILES CC(C)(C)c1cccc(NCCc2cnc[nH]2)c1 Show InChI InChI=1S/C15H21N3/c1-15(2,3)12-5-4-6-13(9-12)17-8-7-14-10-16-11-18-14/h4-6,9-11,17H,7-8H2,1-3H3,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11695 ((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...) Show SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N |r,TLB:9:8:6:3.2.4,4:3:10:7.6.5,4:5:10:3.2.9,THB:9:3:6:10.7.8,11:8:6:3.2.4| Show InChI InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4 in human plasma using Gly-Pro-AMC as substrate by fluorimetric analysis				Bioorg Med Chem 20: 5864-83 (2012) Article DOI: 10.1016/j.bmc.2012.07.046 BindingDB Entry DOI: 10.7270/Q2FX7BJX
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317866 (4-(2-(4-Cyclohexylphenylamino)ethyl)-1H-imidazole ...) Show SMILES C(Cc1cnc[nH]1)Nc1ccc(cc1)C1CCCCC1 Show InChI InChI=1S/C17H23N3/c1-2-4-14(5-3-1)15-6-8-16(9-7-15)19-11-10-17-12-18-13-20-17/h6-9,12-14,19H,1-5,10-11H2,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM7966 (2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...) Show SMILES NCCc1cnc[nH]1 Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321816 (4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)pi...) Show SMILES COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C16H21N3O/c1-20-16-4-2-15(3-5-16)19-8-6-13(7-9-19)10-14-11-17-12-18-14/h2-5,11-13H,6-10H2,1H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50364378 (CHEMBL1950289) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n([C@H]3CCOC3)c2n1 |r,wU:1.0,wD:4.7,25.26,(-6.26,-6.49,;-5.49,-5.16,;-6.25,-3.82,;-5.49,-2.5,;-3.95,-2.49,;-3.17,-3.82,;-3.94,-5.16,;-3.19,-1.16,;-1.65,-1.15,;-.89,.17,;.66,.18,;1.42,-1.15,;2.92,-1.46,;3.09,-2.98,;4.42,-3.75,;5.75,-2.97,;5.74,-1.45,;4.4,-.69,;7.06,-.67,;8.41,-1.43,;9.74,-.66,;8.41,-2.97,;7.08,-3.75,;7.08,-5.29,;1.69,-3.61,;1.23,-5.08,;-.23,-5.56,;-.23,-7.1,;1.24,-7.57,;2.14,-6.32,;.66,-2.48,;-.88,-2.48,)| Show InChI InChI=1S/C21H23F3N6O2/c22-11-7-15(23)18(16(24)8-11)28-21-27-17-9-25-20(26-12-1-3-14(31)4-2-12)29-19(17)30(21)13-5-6-32-10-13/h7-9,12-14,31H,1-6,10H2,(H,27,28)(H,25,26,29)/t12-,13-,14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of hexa-His-tagged JNK2 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...				Bioorg Med Chem Lett 22: 1433-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.027 BindingDB Entry DOI: 10.7270/Q2C829SK
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317869 (4-(2-(3,4-Dimethylphenylamino)ethyl)-1H-imidazole ...) Show SMILES Cc1ccc(NCCc2cnc[nH]2)cc1C Show InChI InChI=1S/C13H17N3/c1-10-3-4-12(7-11(10)2)15-6-5-13-8-14-9-16-13/h3-4,7-9,15H,5-6H2,1-2H3,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321821 (4-((1H-Imidazol-4-yl)methyl)-1-(4-fluorophenyl)pip...) Show SMILES Fc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C15H18FN3/c16-13-1-3-15(4-2-13)19-7-5-12(6-8-19)9-14-10-17-11-18-14/h1-4,10-12H,5-9H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321824 (4-((1H-Imidazol-4-yl)methyl)-1-(4-isopropylphenyl)...) Show SMILES CC(C)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H25N3/c1-14(2)16-3-5-18(6-4-16)21-9-7-15(8-10-21)11-17-12-19-13-20-17/h3-6,12-15H,7-11H2,1-2H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317870 (4-(2-(4-Methylphenylamino)ethyl)-1H-imidazole | CH...) Show SMILES Cc1ccc(NCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H15N3/c1-10-2-4-11(5-3-10)14-7-6-12-8-13-9-15-12/h2-5,8-9,14H,6-7H2,1H3,(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50326285 ((S)-4-(1-(1H-Imidazol-4-yl)-2-(4-(trifluoromethyl)...) Show SMILES FC(F)(F)c1ccc(SC[C@@H](C2CCNCC2)c2cnc[nH]2)cc1 |r| Show InChI InChI=1S/C17H20F3N3S/c18-17(19,20)13-1-3-14(4-2-13)24-10-15(16-9-22-11-23-16)12-5-7-21-8-6-12/h1-4,9,11-12,15,21H,5-8,10H2,(H,22,23)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321825 (4-((1H-Imidazol-4-yl)methyl)-1-(4-tert-butylphenyl...) Show SMILES CC(C)(C)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C19H27N3/c1-19(2,3)16-4-6-18(7-5-16)22-10-8-15(9-11-22)12-17-13-20-14-21-17/h4-7,13-15H,8-12H2,1-3H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321828 (4-((1H-Imidazol-4-yl)methyl)-1-(naphthalen-2-yl)pi...) Show SMILES C(C1CCN(CC1)c1ccc2ccccc2c1)c1cnc[nH]1 Show InChI InChI=1S/C19H21N3/c1-2-4-17-12-19(6-5-16(17)3-1)22-9-7-15(8-10-22)11-18-13-20-14-21-18/h1-6,12-15H,7-11H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50326287 (2-(2-(4-tert-Butylphenylthio)-1-(1H-imidazol-4-yl)...) Show SMILES CC(C)(C)c1ccc(SCC(c2cnc[nH]2)c2ccccn2)cc1 Show InChI InChI=1S/C20H23N3S/c1-20(2,3)15-7-9-16(10-8-15)24-13-17(19-12-21-14-23-19)18-6-4-5-11-22-18/h4-12,14,17H,13H2,1-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50326289 (4-(1-(1H-Imidazole-4-yl)-2-(4-trifluoromeethylphen...) Show SMILES FC(F)(F)c1ccc(SCC(c2cnc[nH]2)c2ccncc2)cc1 Show InChI InChI=1S/C17H14F3N3S/c18-17(19,20)13-1-3-14(4-2-13)24-10-15(16-9-22-11-23-16)12-5-7-21-8-6-12/h1-9,11,15H,10H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Binding affinity to human histamine H4 receptor				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50326286 ((R)-4-(1-(1H-Imidazol-4-yl)-2-(4-(trifluoromethyl)...) Show SMILES FC(F)(F)c1ccc(SC[C@H](C2CCNCC2)c2cnc[nH]2)cc1 |r| Show InChI InChI=1S/C17H20F3N3S/c18-17(19,20)13-1-3-14(4-2-13)24-10-15(16-9-22-11-23-16)12-5-7-21-8-6-12/h1-4,9,11-12,15,21H,5-8,10H2,(H,22,23)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321822 (4-((1H-Imidazol-4-yl)methyl)-1-(4-nitrophenyl)pipe...) Show SMILES [O-][N+](=O)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C15H18N4O2/c20-19(21)15-3-1-14(2-4-15)18-7-5-12(6-8-18)9-13-10-16-11-17-13/h1-4,10-12H,5-9H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM22542 (4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...) Show SMILES C(C1CCNCC1)c1cnc[nH]1 Show InChI InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317863 (4-(2-(4-Methoxyphenylamino)ethyl)-1H-imidazole | C...) Show SMILES COc1ccc(SCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H14N2OS/c1-15-11-2-4-12(5-3-11)16-7-6-10-8-13-9-14-10/h2-5,8-9H,6-7H2,1H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321820 (4-((1H-Imidazol-4-yl)methyl)-1-phenylpiperidine | ...) Show SMILES C(C1CCN(CC1)c1ccccc1)c1cnc[nH]1 Show InChI InChI=1S/C15H19N3/c1-2-4-15(5-3-1)18-8-6-13(7-9-18)10-14-11-16-12-17-14/h1-5,11-13H,6-10H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50364378 (CHEMBL1950289) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n([C@H]3CCOC3)c2n1 |r,wU:1.0,wD:4.7,25.26,(-6.26,-6.49,;-5.49,-5.16,;-6.25,-3.82,;-5.49,-2.5,;-3.95,-2.49,;-3.17,-3.82,;-3.94,-5.16,;-3.19,-1.16,;-1.65,-1.15,;-.89,.17,;.66,.18,;1.42,-1.15,;2.92,-1.46,;3.09,-2.98,;4.42,-3.75,;5.75,-2.97,;5.74,-1.45,;4.4,-.69,;7.06,-.67,;8.41,-1.43,;9.74,-.66,;8.41,-2.97,;7.08,-3.75,;7.08,-5.29,;1.69,-3.61,;1.23,-5.08,;-.23,-5.56,;-.23,-7.1,;1.24,-7.57,;2.14,-6.32,;.66,-2.48,;-.88,-2.48,)| Show InChI InChI=1S/C21H23F3N6O2/c22-11-7-15(23)18(16(24)8-11)28-21-27-17-9-25-20(26-12-1-3-14(31)4-2-12)29-19(17)30(21)13-5-6-32-10-13/h7-9,12-14,31H,1-6,10H2,(H,27,28)(H,25,26,29)/t12-,13-,14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...				Bioorg Med Chem Lett 22: 1433-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.027 BindingDB Entry DOI: 10.7270/Q2C829SK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histamine H1 receptor (Homo sapiens (Human))	BDBM50326286 ((R)-4-(1-(1H-Imidazol-4-yl)-2-(4-(trifluoromethyl)...) Show SMILES FC(F)(F)c1ccc(SC[C@H](C2CCNCC2)c2cnc[nH]2)cc1 |r| Show InChI InChI=1S/C17H20F3N3S/c18-17(19,20)13-1-3-14(4-2-13)24-10-15(16-9-22-11-23-16)12-5-7-21-8-6-12/h1-4,9,11-12,15,21H,5-8,10H2,(H,22,23)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Binding affinity to human histamine H1 receptor				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317871 (4-(2-(Phenylamino)ethyl)-1H-imidazole | CHEMBL1096...) Show SMILES C(Cc1cnc[nH]1)Nc1ccccc1 Show InChI InChI=1S/C11H13N3/c1-2-4-10(5-3-1)13-7-6-11-8-12-9-14-11/h1-5,8-9,13H,6-7H2,(H,12,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...				J Med Chem 53: 3840-4 (2010) Article DOI: 10.1021/jm901890s BindingDB Entry DOI: 10.7270/Q21Z44KC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321814 (4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)pipe...) Show SMILES C(C1CCN(CC1)c1ccc(cc1)-c1ccccc1)c1cnc[nH]1 Show InChI InChI=1S/C21H23N3/c1-2-4-18(5-3-1)19-6-8-21(9-7-19)24-12-10-17(11-13-24)14-20-15-22-16-23-20/h1-9,15-17H,10-14H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50326288 (3-(2-(4-tert-Butylphenylthio)-1-(1H-imidazol-4-yl)...) Show SMILES CC(C)(C)c1ccc(SCC(c2cnc[nH]2)c2cccnc2)cc1 Show InChI InChI=1S/C20H23N3S/c1-20(2,3)16-6-8-17(9-7-16)24-13-18(19-12-22-14-23-19)15-5-4-10-21-11-15/h4-12,14,18H,13H2,1-3H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 6445-56 (2010) Article DOI: 10.1021/jm100643t BindingDB Entry DOI: 10.7270/Q2QF8T3X
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (GUINEA PIG)	BDBM50185261 (4-(3,4-dichlorobenzamido)-5-((3-methoxypropyl)(pen...) Show SMILES CCCCCN(CCCOC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 571-5 (1994) BindingDB Entry DOI: 10.7270/Q2WQ029S
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (GUINEA PIG)	BDBM50084033 (1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-pheny...) Show SMILES Fc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8| Show InChI InChI=1S/C26H19FN4O2/c27-19-10-3-2-8-17(19)22-18-9-5-7-15-12-13-31(23(15)18)26(33)24(29-22)30-25(32)21-14-16-6-1-4-11-20(16)28-21/h1-11,14,24,28H,12-13H2,(H,30,32)/t24-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 571-5 (1994) BindingDB Entry DOI: 10.7270/Q2WQ029S
					More data for this Ligand-Target Pair

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