Compile Data Set for Download or QSAR

Found 228 hits with Last Name = 'sawamoto' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220924 (US9302996, 39) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(cc1)-c1ncc([nH]1)C1(CC1)C(F)(F)F Show InChI InChI=1S/C24H24F3N3O3/c1-14-10-19(33-13-22(2,3)21(31)32)28-11-17(14)15-4-6-16(7-5-15)20-29-12-18(30-20)23(8-9-23)24(25,26)27/h4-7,10-12H,8-9,13H2,1-3H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.630	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220966 (US9302996, 114 | US9302996, 81) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(C)c1 Show InChI InChI=1S/C21H21F3N4O3/c1-11-6-16(31-10-20(3,4)19(29)30)25-8-14(11)13-5-12(2)17(26-7-13)18-27-9-15(28-18)21(22,23)24/h5-9H,10H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220983 (US9302996, 98-3) Show SMILES Cc1cc(OCC2(CCC2)C(O)=O)ncc1-c1ccc(-c2nc(c[nH]2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C22H19F4N3O3/c1-12-7-18(32-11-21(20(30)31)5-2-6-21)27-9-15(12)13-3-4-14(16(23)8-13)19-28-10-17(29-19)22(24,25)26/h3-4,7-10H,2,5-6,11H2,1H3,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.75	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220908 (US9302996, 23) Show SMILES CCC(CC)(COc1ccc(cn1)-c1ccc(nc1)-c1ncc([nH]1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C21H21F3N4O3/c1-3-20(4-2,19(29)30)12-31-17-8-6-14(10-26-17)13-5-7-15(25-9-13)18-27-11-16(28-18)21(22,23)24/h5-11H,3-4,12H2,1-2H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.760	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220962 (US9302996, 77) Show SMILES Cc1cc(ccc1-c1ncc([nH]1)C(F)(F)F)-c1cnc(OCC(C)(C)C(O)=O)cc1C Show InChI InChI=1S/C22H22F3N3O3/c1-12-7-14(5-6-15(12)19-27-10-17(28-19)22(23,24)25)16-9-26-18(8-13(16)2)31-11-21(3,4)20(29)30/h5-10H,11H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.780	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395359 (US10308636, Example 44-6) Show SMILES OC(=O)c1cccc(OCC2CCN(CC2)c2ccc(cn2)-c2nc(c[nH]2)C(F)(F)F)c1Cl Show InChI InChI=1S/C22H20ClF3N4O3/c23-19-15(21(31)32)2-1-3-16(19)33-12-13-6-8-30(9-7-13)18-5-4-14(10-27-18)20-28-11-17(29-20)22(24,25)26/h1-5,10-11,13H,6-9,12H2,(H,28,29)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220986 (US9302996, 101-3) Show SMILES Cc1cc(OCC2(CCC2)C(O)=O)ncc1-c1ccc(-c2nc(c[nH]2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C22H19ClF3N3O3/c1-12-7-18(32-11-21(20(30)31)5-2-6-21)27-9-15(12)13-3-4-14(16(23)8-13)19-28-10-17(29-19)22(24,25)26/h3-4,7-10H,2,5-6,11H2,1H3,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.820	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220975 (US9302996, 90) Show SMILES CC(C)(COc1ncc(cc1F)-c1ccc(cc1)-c1ncc([nH]1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C20H17F4N3O3/c1-19(2,18(28)29)10-30-17-14(21)7-13(8-26-17)11-3-5-12(6-4-11)16-25-9-15(27-16)20(22,23)24/h3-9H,10H2,1-2H3,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.870	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395327 (US10308636, Example 4-15) Show SMILES CCC(CC)(COc1cnc(cn1)-c1ccc(nc1)-c1ncc([nH]1)-c1ccccc1)C(O)=O Show InChI InChI=1S/C25H25N5O3/c1-3-25(4-2,24(31)32)16-33-22-15-27-20(13-28-22)18-10-11-19(26-12-18)23-29-14-21(30-23)17-8-6-5-7-9-17/h5-15H,3-4,16H2,1-2H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220947 (US9302996, 62-3) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(-c2nc(c[nH]2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C21H19F4N3O3/c1-11-6-17(31-10-20(2,3)19(29)30)26-8-14(11)12-4-5-13(15(22)7-12)18-27-9-16(28-18)21(23,24)25/h4-9H,10H2,1-3H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.960	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221020 (US9302996, 135) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C21H18ClF5N4O3/c1-10-4-15(34-9-19(2,3)18(32)33)28-7-12(10)11-5-13(22)16(29-6-11)17-30-8-14(31-17)20(23,24)21(25,26)27/h4-8H,9H2,1-3H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395378 (US10308636, Example 110) Show SMILES COC(=O)C(C)(C)COc1ccc(cn1)-c1ccc(cc1)-c1nc(n[nH]1)-c1ccc(OC)cc1 Show InChI InChI=1S/C26H26N4O4/c1-26(2,25(31)33-4)16-34-22-14-11-20(15-27-22)17-5-7-18(8-6-17)23-28-24(30-29-23)19-9-12-21(32-3)13-10-19/h5-15H,16H2,1-4H3,(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395380 (US10308636, Example 75) Show SMILES COC(=O)C(C)(C)COc1ccc(cn1)-c1ccc(cc1)-c1nc(Oc2ccc(cc2)C#N)n(COCC[Si](C)(C)C)n1 Show InChI InChI=1S/C32H37N5O5Si/c1-32(2,30(38)39-3)21-41-28-16-13-26(20-34-28)24-9-11-25(12-10-24)29-35-31(42-27-14-7-23(19-33)8-15-27)37(36-29)22-40-17-18-43(4,5)6/h7-16,20H,17-18,21-22H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395381 (US10308636, Example 74) Show SMILES COC(=O)C(C)(C)COc1ccc(cn1)-c1ccc(cc1)-c1nc(OCC(F)(F)C(F)(F)F)n(COCC[Si](C)(C)C)n1 Show InChI InChI=1S/C28H35F5N4O5Si/c1-26(2,24(38)39-3)16-41-22-12-11-21(15-34-22)19-7-9-20(10-8-19)23-35-25(42-17-27(29,30)28(31,32)33)37(36-23)18-40-13-14-43(4,5)6/h7-12,15H,13-14,16-18H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220993 (US9302996, 108) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(cc1)-c1ncc(CC2CC2)[nH]1 Show InChI InChI=1S/C24H27N3O3/c1-15-10-21(30-14-24(2,3)23(28)29)25-13-20(15)17-6-8-18(9-7-17)22-26-12-19(27-22)11-16-4-5-16/h6-10,12-13,16H,4-5,11,14H2,1-3H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220948 (US9302996, 63-3) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(-c2nc(c[nH]2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C21H19ClF3N3O3/c1-11-6-17(31-10-20(2,3)19(29)30)26-8-14(11)12-4-5-13(15(22)7-12)18-27-9-16(28-18)21(23,24)25/h4-9H,10H2,1-3H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395364 (US10308636, Example 46-5) Show SMILES Fc1ccccc1OC[C@H]1CC[C@@H](CC1)c1ccc(cn1)-c1nc(c[nH]1)C(F)(F)F |r,wU:12.16,wD:9.9,(-7.12,-1.57,;-7.12,-3.11,;-8.5,-3.85,;-8.45,-5.42,;-7.12,-6.19,;-5.79,-5.42,;-5.79,-3.88,;-4.45,-3.11,;-3.12,-3.88,;-1.78,-3.11,;-.45,-3.88,;.88,-3.11,;.88,-1.57,;-.45,-.8,;-1.78,-1.57,;2.22,-.8,;2.22,.74,;3.55,1.51,;4.88,.74,;4.88,-.8,;3.55,-1.57,;6.22,1.51,;6.22,3.05,;7.7,3.56,;8.59,2.28,;7.68,1.03,;8.17,5.03,;8.65,6.49,;9.64,4.55,;6.71,5.5,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220997 (US9302996, 112) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C20H18ClF3N4O3/c1-10-4-15(31-9-19(2,3)18(29)30)25-7-12(10)11-5-13(21)16(26-6-11)17-27-8-14(28-17)20(22,23)24/h4-8H,9H2,1-3H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220992 (US9302996, 107) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C20H18F4N4O3/c1-10-4-15(31-9-19(2,3)18(29)30)25-7-12(10)11-5-13(21)16(26-6-11)17-27-8-14(28-17)20(22,23)24/h4-8H,9H2,1-3H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220886 (US9302996, 1-3) Show SMILES CC(C)(COc1ccc(cc1)-c1ccc(cn1)-c1nc(c[nH]1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C20H18F3N3O3/c1-19(2,18(27)28)11-29-14-6-3-12(4-7-14)15-8-5-13(9-24-15)17-25-10-16(26-17)20(21,22)23/h3-10H,11H2,1-2H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395361 (US10308636, Example 45-1) Show SMILES CCOC(=O)c1cccc(OCC2CCN(CC2)c2ccc(cc2)-c2nc(cn2COCC[Si](C)(C)C)C(F)(F)F)c1C Show InChI InChI=1S/C32H42F3N3O4Si/c1-6-41-31(39)27-8-7-9-28(23(27)2)42-21-24-14-16-37(17-15-24)26-12-10-25(11-13-26)30-36-29(32(33,34)35)20-38(30)22-40-18-19-43(3,4)5/h7-13,20,24H,6,14-19,21-22H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220939 (US9302996, 54-4) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(-c2ncc([nH]2)C2(CC2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C24H23F4N3O3/c1-13-8-19(34-12-22(2,3)21(32)33)29-10-16(13)14-4-5-15(17(25)9-14)20-30-11-18(31-20)23(6-7-23)24(26,27)28/h4-5,8-11H,6-7,12H2,1-3H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221019 (US9302996, 134) Show SMILES CCC(CC)(COc1cc(C)c(cn1)-c1ccc(-c2ncc([nH]2)C(F)(F)F)c(F)c1)C(O)=O Show InChI InChI=1S/C23H23F4N3O3/c1-4-22(5-2,21(31)32)12-33-19-8-13(3)16(10-28-19)14-6-7-15(17(24)9-14)20-29-11-18(30-20)23(25,26)27/h6-11H,4-5,12H2,1-3H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220961 (US9302996, 76) Show SMILES CC(C)(COc1ccc(cn1)-c1ccc(-c2ncc([nH]2)C(F)(F)F)c(F)c1)C(O)=O Show InChI InChI=1S/C20H17F4N3O3/c1-19(2,18(28)29)10-30-16-6-4-12(8-25-16)11-3-5-13(14(21)7-11)17-26-9-15(27-17)20(22,23)24/h3-9H,10H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220984 (US9302996, 99-6) Show SMILES Cc1cc(OCC2(CCC2)C(O)=O)ncc1-c1cnc(-c2nc(c[nH]2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C21H18ClF3N4O3/c1-11-5-16(32-10-20(19(30)31)3-2-4-20)26-8-13(11)12-6-14(22)17(27-7-12)18-28-9-15(29-18)21(23,24)25/h5-9H,2-4,10H2,1H3,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221018 (US9302996, 133) Show SMILES Cc1cc(OCC2(CC2)C(O)=O)ncc1-c1ccc(-c2ncc([nH]2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C21H17F4N3O3/c1-11-6-17(31-10-20(4-5-20)19(29)30)26-8-14(11)12-2-3-13(15(22)7-12)18-27-9-16(28-18)21(23,24)25/h2-3,6-9H,4-5,10H2,1H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221011 (US9302996, 126) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(nc1)-c1ncc([nH]1)C(F)(F)F Show InChI InChI=1S/C19H18F3N5O3/c1-10-4-14(30-9-18(2,3)17(28)29)23-7-12(10)11-5-24-15(25-6-11)16-26-8-13(27-16)19(20,21)22/h4-8H,9H2,1-3H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220980 (US9302996, 95-6) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(cn1)-c1nc(c[nH]1)C(F)(F)F Show InChI InChI=1S/C19H18F3N5O3/c1-10-4-15(30-9-18(2,3)17(28)29)25-5-11(10)12-6-24-13(7-23-12)16-26-8-14(27-16)19(20,21)22/h4-8H,9H2,1-3H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395325 (US10308636, Example 4-1) Show SMILES Cc1cc(OCC(C)(C)C(=O)OC(C)(C)C)ncc1-c1cnc(-c2ncc([nH]2)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C29H31FN4O3/c1-18-12-24(36-17-29(5,6)27(35)37-28(2,3)4)31-15-21(18)20-13-22(30)25(32-14-20)26-33-16-23(34-26)19-10-8-7-9-11-19/h7-16H,17H2,1-6H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221023 (US9302996, 138) Show SMILES CCC(CC)(COc1cc(C)c(cn1)-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(F)c1)C(O)=O Show InChI InChI=1S/C22H22F4N4O3/c1-4-21(5-2,20(31)32)11-33-17-6-12(3)14(9-27-17)13-7-15(23)18(28-8-13)19-29-10-16(30-19)22(24,25)26/h6-10H,4-5,11H2,1-3H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395383 (US10308636, Example 78) Show SMILES NC(=O)c1ccc(Br)cc1F Show InChI InChI=1S/C7H5BrFNO/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H2,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395345 (US10308636, Example 32-2) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(cc1)-c1nc(c[nH]1)C#N Show InChI InChI=1S/C21H20N4O3/c1-13-8-18(28-12-21(2,3)20(26)27)23-11-17(13)14-4-6-15(7-5-14)19-24-10-16(9-22)25-19/h4-8,10-11H,12H2,1-3H3,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221033 (US9302996, 148) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(cn1)-c1ncc([nH]1)C(F)(F)C(F)(F)F Show InChI InChI=1S/C20H18F5N5O3/c1-10-4-15(33-9-18(2,3)17(31)32)28-5-11(10)12-6-27-13(7-26-12)16-29-8-14(30-16)19(21,22)20(23,24)25/h4-8H,9H2,1-3H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220937 (US9302996, 52) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(-c2ncc([nH]2)C2(CCC2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C25H25F4N3O3/c1-14-9-20(35-13-23(2,3)22(33)34)30-11-17(14)15-5-6-16(18(26)10-15)21-31-12-19(32-21)24(7-4-8-24)25(27,28)29/h5-6,9-12H,4,7-8,13H2,1-3H3,(H,31,32)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395386 (US10308636, Example 83) Show SMILES C[Si](C)(C)CCOCn1nc(nc1Oc1ccc(F)cc1)-c1ccc(Br)cc1F Show InChI InChI=1S/C20H22BrF2N3O2Si/c1-29(2,3)11-10-27-13-26-20(28-16-7-5-15(22)6-8-16)24-19(25-26)17-9-4-14(21)12-18(17)23/h4-9,12H,10-11,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221005 (US9302996, 120) Show SMILES CC(C)Cc1cnc([nH]1)-c1ccc(cc1Cl)-c1cnc(OCC(C)(C)C(O)=O)cc1C Show InChI InChI=1S/C24H28ClN3O3/c1-14(2)8-17-11-27-22(28-17)18-7-6-16(10-20(18)25)19-12-26-21(9-15(19)3)31-13-24(4,5)23(29)30/h6-7,9-12,14H,8,13H2,1-5H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221021 (US9302996, 136) Show SMILES Cc1cc(OCC2(CC2)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C20H16F4N4O3/c1-10-4-15(31-9-19(2-3-19)18(29)30)25-7-12(10)11-5-13(21)16(26-6-11)17-27-8-14(28-17)20(22,23)24/h4-8H,2-3,9H2,1H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220889 (US9302996, 4-2) Show SMILES CC(C)(COc1ccc(cc1F)-c1ccc(cn1)-c1nc(c[nH]1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C20H17F4N3O3/c1-19(2,18(28)29)10-30-15-6-4-11(7-13(15)21)14-5-3-12(8-25-14)17-26-9-16(27-17)20(22,23)24/h3-9H,10H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221022 (US9302996, 137) Show SMILES Cc1cc(OCC2(CCC2)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C21H18F4N4O3/c1-11-5-16(32-10-20(19(30)31)3-2-4-20)26-8-13(11)12-6-14(22)17(27-7-12)18-28-9-15(29-18)21(23,24)25/h5-9H,2-4,10H2,1H3,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220950 (US9302996, 65) Show SMILES CC(C)(COc1ccc(cc1)-c1ccc(cn1)-c1ncc([nH]1)C(F)(F)F)CC(O)=O Show InChI InChI=1S/C21H20F3N3O3/c1-20(2,9-18(28)29)12-30-15-6-3-13(4-7-15)16-8-5-14(10-25-16)19-26-11-17(27-19)21(22,23)24/h3-8,10-11H,9,12H2,1-2H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220969 (US9302996, 84) Show SMILES CC(C)(COc1ncc(cc1F)-c1ccc(-c2ncc([nH]2)C(F)(F)F)c(F)c1)C(O)=O Show InChI InChI=1S/C20H16F5N3O3/c1-19(2,18(29)30)9-31-17-14(22)6-11(7-27-17)10-3-4-12(13(21)5-10)16-26-8-15(28-16)20(23,24)25/h3-8H,9H2,1-2H3,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220958 (US9302996, 73) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(cc1)-c1ncc([nH]1)C(F)(F)F Show InChI InChI=1S/C21H20F3N3O3/c1-12-8-17(30-11-20(2,3)19(28)29)25-9-15(12)13-4-6-14(7-5-13)18-26-10-16(27-18)21(22,23)24/h4-10H,11H2,1-3H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395313 (US10308636, Example 1-34) Show SMILES CC(C)(COc1ccc(cc1)-c1ccc(cn1)-c1ncc([nH]1)-c1cccs1)C(O)=O Show InChI InChI=1S/C23H21N3O3S/c1-23(2,22(27)28)14-29-17-8-5-15(6-9-17)18-10-7-16(12-24-18)21-25-13-19(26-21)20-4-3-11-30-20/h3-13H,14H2,1-2H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395326 (US10308636, Example 4-3) Show SMILES Cc1cc(OCC2(CCC2)C(O)=O)ncc1-c1cnc(nc1)-c1ncc([nH]1)-c1ccccc1 Show InChI InChI=1S/C25H23N5O3/c1-16-10-21(33-15-25(24(31)32)8-5-9-25)26-13-19(16)18-11-27-22(28-12-18)23-29-14-20(30-23)17-6-3-2-4-7-17/h2-4,6-7,10-14H,5,8-9,15H2,1H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221025 (US9302996, 140) Show SMILES CCC(CC)(COc1cc(C)c(cn1)-c1ccc(-c2ncc([nH]2)C(F)(F)F)c(Cl)c1)C(O)=O Show InChI InChI=1S/C23H23ClF3N3O3/c1-4-22(5-2,21(31)32)12-33-19-8-13(3)16(10-28-19)14-6-7-15(17(24)9-14)20-29-11-18(30-20)23(25,26)27/h6-11H,4-5,12H2,1-3H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221009 (US9302996, 124) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(-c2ncc([nH]2)C(F)(F)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C22H19F6N3O3/c1-11-6-17(34-10-20(2,3)19(32)33)29-8-14(11)12-4-5-13(15(23)7-12)18-30-9-16(31-18)21(24,25)22(26,27)28/h4-9H,10H2,1-3H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395379 (US10308636, Example 72) Show SMILES COC(=O)C(C)(C)COc1ccc(cn1)-c1ccc(cc1)-c1nc(Oc2cccnc2)n(COCC[Si](C)(C)C)n1 Show InChI InChI=1S/C30H37N5O5Si/c1-30(2,28(36)37-3)20-39-26-14-13-24(18-32-26)22-9-11-23(12-10-22)27-33-29(40-25-8-7-15-31-19-25)35(34-27)21-38-16-17-41(4,5)6/h7-15,18-19H,16-17,20-21H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220960 (US9302996, 75) Show SMILES CC(C)(COc1ccc(c(F)c1F)-c1ccc(cn1)-c1ncc([nH]1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C20H16F5N3O3/c1-19(2,18(29)30)9-31-13-6-4-11(15(21)16(13)22)12-5-3-10(7-26-12)17-27-8-14(28-17)20(23,24)25/h3-8H,9H2,1-2H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220994 (US9302996, 109) Show SMILES Cc1cc(ccc1-c1ncc(CC2CC2)[nH]1)-c1cnc(OCC(C)(C)C(O)=O)cc1C Show InChI InChI=1S/C25H29N3O3/c1-15-9-18(7-8-20(15)23-27-12-19(28-23)11-17-5-6-17)21-13-26-22(10-16(21)2)31-14-25(3,4)24(29)30/h7-10,12-13,17H,5-6,11,14H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM221010 (US9302996, 125) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(-c2ncc([nH]2)C(F)(F)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C22H19ClF5N3O3/c1-11-6-17(34-10-20(2,3)19(32)33)29-8-14(11)12-4-5-13(15(23)7-12)18-30-9-16(31-18)21(24,25)22(26,27)28/h4-9H,10H2,1-3H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair

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