Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50232153 ((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0300 | -55.8 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM139371 (eplivanserin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 0.0460 | -54.8 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.0830 | -53.5 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.440 | -49.6 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM139370 (ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem | Article PubMed | 0.5 | -49.3 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 0.550 | -49.1 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM139371 (eplivanserin) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.30 | -47.1 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 1.30 | -47.1 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM139370 (ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem | Article PubMed | 1.60 | -46.7 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50232153 ((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.80 | -44.7 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
ACADIA Pharmaceuticals Inc. | Assay Description For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe... | J Pharmacol Exp Ther 317: 910-8 (2006) Article DOI: 10.1124/jpet.105.097006 BindingDB Entry DOI: 10.7270/Q269728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM50582430 (CHEMBL4598390) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 3H-RL338 from human GPR6 expressed in T-REx-CHO-GPR6 cells assessed as inhibition constant by competition binding assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02081 BindingDB Entry DOI: 10.7270/Q2JW8JSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM50582450 (CHEMBL4778540) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 3H-RL338 from human GPR6 expressed in T-REx-CHO-GPR6 cells assessed as inhibition constant by competition binding assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02081 BindingDB Entry DOI: 10.7270/Q2JW8JSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM50582449 (CHEMBL5093828) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of 3H-RL338 from human GPR6 expressed in T-REx-CHO-GPR6 cells assessed as inhibition constant by competition binding assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02081 BindingDB Entry DOI: 10.7270/Q2JW8JSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263504 ((s)?n-(1-(2-fluoro-4-(trifluoromethoxy)phenyl)ethy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263369 ((s)-2-(5-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263453 ((s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263420 ((s)?n-(1-(2,4-dimethylphenyl)ethyl)-2-(4-oxobenzo[...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263490 ((s)-2-(5-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263482 ((s)-2-(8-fluoro-6-methyl-4-oxobenzo[d][1,2,3]triaz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263368 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 119 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263501 ((s)?n-(1-(4-(difluoromethoxy)phenyl)ethyl)-2-(5-me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263502 ((s)?n-(1-(2-fluoro-4-(trifluoromethoxy)phenyl)ethy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263440 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 148 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263497 ((s)?n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 152 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263485 ((s)?n-(1-(2-fluoro-4-methylphenyl)ethyl)-2-(4-oxob...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 171 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263463 ((s)-2-(6-methyl-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 179 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263445 ((s)-2-(6-fluoro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 182 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263454 ((s)-2-(6-chloro-4-oxobenzo[d][1,2,3]triazin-3 (4h)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 189 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263391 ((s)?n-(1-(4-chlorophenyl)ethyl)-2-(4-oxobenzo[d][1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 228 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263480 ((s)-2-(4-oxo-6-(trifluoromethyl)benzo[d][1,2,3]tri...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 435 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263471 ((s)-2-(7-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 437 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263370 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 467 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566740 (CHEMBL4776509) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 486 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263498 ((s)?n-(1-(4-(difluoromethoxy)phenyl)ethyl)-2-(4-ox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 677 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566743 (CHEMBL4847108) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 714 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263465 ((s)-2-(8-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 791 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263510 ((s)?n-(1-(4-methoxyphenyl)propan-2-yl)-2-(4-oxoben...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 802 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566744 (CHEMBL4871506) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 869 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263435 ((s)?n-(1-(4-ethoxyphenyl)ethyl)-2-(4-oxobenzo[d][1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 953 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263433 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566728 (CHEMBL4866435) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566752 (CHEMBL4874147) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263505 (US10561662, Example 74 | US11173161, EX 74 | US955...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263385 ((s)?n-(1-(4-methoxyphenyl)ethyl)-2-(4-oxobenzo[d][...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263483 ((s)?n-(1-(2-methoxy-4-methylphenyl)ethyl)-2-(4-oxo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566738 (CHEMBL4861019) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263506 (US10561662, Example 75 | US11173161, EX 75 | US955...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566756 (CHEMBL4855076) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM50566736 (CHEMBL4874254) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263437 ((s)?n-(1-(2,4-dimethoxyphenyl)ethyl)-2-(4-oxobenzo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of (S)-N-(1-(2-[3H]-4-methoxyphenyl)propan-2-yl)-2-(2,3-dimethyl-7-oxothieno[2,3-d]pyridazin-6(7H)-yl)acetamide from human GPR139 expres... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00820 BindingDB Entry DOI: 10.7270/Q25B068P | |||||||||||
More data for this Ligand-Target Pair |
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