Found 7 hits with Last Name = 'schmitz' and Initial = 'fj' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50135851
(2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxy-phenox...)Show SMILES Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)c(Br)c1Br Show InChI InChI=1S/C12H4Br6O3/c13-3-1-4(14)10(19)5(2-3)21-12-9(18)7(16)6(15)8(17)11(12)20/h1-2,19-20H | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 15-lipoxygenase |
J Nat Prod 58: 1384-1391 (1995)
Article DOI: 10.1021/np50123a008
BindingDB Entry DOI: 10.7270/Q22B8Z26 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50150788
(2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...)Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 15-lipoxygenase |
J Nat Prod 58: 1384-1391 (1995)
Article DOI: 10.1021/np50123a008
BindingDB Entry DOI: 10.7270/Q22B8Z26 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50292443
(3,4,5-tribromo-2-(2', 4'-dibromo-phenoxy)phenol | ...)Show InChI InChI=1S/C12H5Br5O2/c13-5-1-2-9(6(14)3-5)19-12-8(18)4-7(15)10(16)11(12)17/h1-4,18H | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 15-lipoxygenase |
J Nat Prod 58: 1384-1391 (1995)
Article DOI: 10.1021/np50123a008
BindingDB Entry DOI: 10.7270/Q22B8Z26 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50292444
(2,3,4-tribromo-6-(2,4-dibromophenoxy)phenol | CHEM...)Show InChI InChI=1S/C12H5Br5O2/c13-5-1-2-8(6(14)3-5)19-9-4-7(15)10(16)11(17)12(9)18/h1-4,18H | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 15-lipoxygenase |
J Nat Prod 58: 1384-1391 (1995)
Article DOI: 10.1021/np50123a008
BindingDB Entry DOI: 10.7270/Q22B8Z26 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM50478536
(Halistanol Sulfate)Show SMILES [Na;v0+].[Na;v0+].[Na;v0+].[H][C@@]1([#6]-[#6][C@@]2([H])[C@]3([H])[#6]-[#6@H](-[#8]S([#8-])(=O)=O)[C@@]4([H])[#6]-[#6@H](-[#8]S([#8-])(=O)=O)-[#6@H](-[#6][C@]4([#6])[C@@]3([H])[#6]-[#6][C@]12[#6])-[#8]S([#8-])(=O)=O)[#6@H](-[#6])-[#6]-[#6]-[#6](-[#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C29H52O12S3.3Na/c1-17(8-9-18(2)27(3,4)5)20-10-11-21-19-14-24(39-42(30,31)32)23-15-25(40-43(33,34)35)26(41-44(36,37)38)16-29(23,7)22(19)12-13-28(20,21)6;;;/h17-26H,8-16H2,1-7H3,(H,30,31,32)(H,33,34,35)(H,36,37,38);;;/q;3*+1/p-3/t17-,18?,19+,20-,21+,22+,23-,24+,25+,26+,28-,29-;;;/m1.../s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oklahoma
Curated by ChEMBL
| Assay Description
Inhibition of CDK4/Cyclin D1 complex formation |
J Nat Prod 66: 686-9 (2003)
Article DOI: 10.1021/np0205506
BindingDB Entry DOI: 10.7270/Q2N0199N |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50232491
(3,5-dibromo-2-(2',4'-dibromophenoxy)phenol | 3,5-d...)Show InChI InChI=1S/C12H6Br4O2/c13-6-1-2-11(8(15)3-6)18-12-9(16)4-7(14)5-10(12)17/h1-5,17H | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 15-lipoxygenase |
J Nat Prod 58: 1384-1391 (1995)
Article DOI: 10.1021/np50123a008
BindingDB Entry DOI: 10.7270/Q22B8Z26 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM50478545
(Siphonodictyal C)Show SMILES [Na;v0+].[H][C@@]12[#6]-[#6]=[#6](-[#6])-[#6@H](-[#6]-c3cc(-[#8])c(-[#8])c(-[#6]=O)c3-[#8]S([#8-])(=O)=O)[C@@]1([#6])[#6]-[#6]-[#6]C2([#6])[#6] |r,t:3| Show InChI InChI=1S/C22H30O7S.Na/c1-13-6-7-18-21(2,3)8-5-9-22(18,4)16(13)10-14-11-17(24)19(25)15(12-23)20(14)29-30(26,27)28;/h6,11-12,16,18,24-25H,5,7-10H2,1-4H3,(H,26,27,28);/q;+1/p-1/t16-,18-,22+;/m0./s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oklahoma
Curated by ChEMBL
| Assay Description
Inhibition of CDK4/Cyclin D1 complex formation |
J Nat Prod 66: 686-9 (2003)
Article DOI: 10.1021/np0205506
BindingDB Entry DOI: 10.7270/Q2N0199N |
More data for this
Ligand-Target Pair | |
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