Compile Data Set for Download or QSAR

Found 65 hits with Last Name = 'schulz' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314131 ((S,E)-Ethyl 4-((R)-2-(tert-Butoxycarbonylamino)-2-...) Show SMILES CCOC(=O)\C=C\[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1 |r| Show InChI InChI=1S/C41H45N3O6/c1-5-49-36(46)29-27-34(42-38(47)37(30-18-10-6-11-19-30)43-39(48)50-40(2,3)4)26-28-35(45)44-41(31-20-12-7-13-21-31,32-22-14-8-15-23-32)33-24-16-9-17-25-33/h6-25,27,29,34,37H,5,26,28H2,1-4H3,(H,42,47)(H,43,48)(H,44,45)/b29-27+/t34-,37+/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314126 ((S)-Benzyl-2-[(Z)-3-((S)-1-benzyloxycarbonyl-2-phe...) Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C/C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C29H28N2O6/c32-26(30-24(28(34)35)18-21-10-4-1-5-11-21)16-17-27(33)31-25(19-22-12-6-2-7-13-22)29(36)37-20-23-14-8-3-9-15-23/h1-17,24-25H,18-20H2,(H,30,32)(H,31,33)(H,34,35)/b17-16-/t24-,25-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1 |r| Show InChI InChI=1S/C41H45N3O6/c1-5-49-36(46)29-27-34(42-38(47)37(30-18-10-6-11-19-30)43-39(48)50-40(2,3)4)26-28-35(45)44-41(31-20-12-7-13-21-31,32-22-14-8-15-23-32)33-24-16-9-17-25-33/h6-25,27,29,34,37H,5,26,28H2,1-4H3,(H,42,47)(H,43,48)(H,44,45)/b29-27+/t34-,37-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay in presence of de...				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314130 ((S)-2-[(E)-3-((S)-1-Benzyloxycarbonyl-2-phenylethy...) Show SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1)\C=C\C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C36H34N2O6/c39-33(37-31(23-27-13-5-1-6-14-27)35(41)43-25-29-17-9-3-10-18-29)21-22-34(40)38-32(24-28-15-7-2-8-16-28)36(42)44-26-30-19-11-4-12-20-30/h1-22,31-32H,23-26H2,(H,37,39)(H,38,40)/b22-21+/t31-,32-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1 |r| Show InChI InChI=1S/C41H45N3O6/c1-5-49-36(46)29-27-34(42-38(47)37(30-18-10-6-11-19-30)43-39(48)50-40(2,3)4)26-28-35(45)44-41(31-20-12-7-13-21-31,32-22-14-8-15-23-32)33-24-16-9-17-25-33/h6-25,27,29,34,37H,5,26,28H2,1-4H3,(H,42,47)(H,43,48)(H,44,45)/b29-27+/t34-,37-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay in presence of d...				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1 |r| Show InChI InChI=1S/C41H45N3O6/c1-5-49-36(46)29-27-34(42-38(47)37(30-18-10-6-11-19-30)43-39(48)50-40(2,3)4)26-28-35(45)44-41(31-20-12-7-13-21-31,32-22-14-8-15-23-32)33-24-16-9-17-25-33/h6-25,27,29,34,37H,5,26,28H2,1-4H3,(H,42,47)(H,43,48)(H,44,45)/b29-27+/t34-,37-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1 |r| Show InChI InChI=1S/C41H45N3O6/c1-5-49-36(46)29-27-34(42-38(47)37(30-18-10-6-11-19-30)43-39(48)50-40(2,3)4)26-28-35(45)44-41(31-20-12-7-13-21-31,32-22-14-8-15-23-32)33-24-16-9-17-25-33/h6-25,27,29,34,37H,5,26,28H2,1-4H3,(H,42,47)(H,43,48)(H,44,45)/b29-27+/t34-,37-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1 |r| Show InChI InChI=1S/C41H45N3O6/c1-5-49-36(46)29-27-34(42-38(47)37(30-18-10-6-11-19-30)43-39(48)50-40(2,3)4)26-28-35(45)44-41(31-20-12-7-13-21-31,32-22-14-8-15-23-32)33-24-16-9-17-25-33/h6-25,27,29,34,37H,5,26,28H2,1-4H3,(H,42,47)(H,43,48)(H,44,45)/b29-27+/t34-,37-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314127 ((S)-Benzyl-2-{(Z)-3-[(S)-1-((S)-1-benzyloxycarbony...) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C/C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C32H33N3O7/c1-22(31(39)40)33-30(38)26(19-23-11-5-2-6-12-23)34-28(36)17-18-29(37)35-27(20-24-13-7-3-8-14-24)32(41)42-21-25-15-9-4-10-16-25/h2-18,22,26-27H,19-21H2,1H3,(H,33,38)(H,34,36)(H,35,37)(H,39,40)/b18-17-/t22-,26-,27-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314128 ((S,E)-Methyl 2-(4-Ethoxy-4-oxobut-2-enamido)-5-oxo...) Show SMILES CCOC(=O)\C=C\C(=O)N[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)OC |r| Show InChI InChI=1S/C31H32N2O6/c1-3-39-29(36)22-21-27(34)32-26(30(37)38-2)19-20-28(35)33-31(23-13-7-4-8-14-23,24-15-9-5-10-16-24)25-17-11-6-12-18-25/h4-18,21-22,26H,3,19-20H2,1-2H3,(H,32,34)(H,33,35)/b22-21+/t26-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314124 ((S,E)-ethyl 4-(tert-butoxycarbonylamino)-7-oxo-7-(...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C33H38N2O5/c1-5-39-30(37)24-22-28(34-31(38)40-32(2,3)4)21-23-29(36)35-33(25-15-9-6-10-16-25,26-17-11-7-12-18-26)27-19-13-8-14-20-27/h6-20,22,24,28H,5,21,23H2,1-4H3,(H,34,38)(H,35,36)/b24-22+/t28-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay in presence of DTT				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314124 ((S,E)-ethyl 4-(tert-butoxycarbonylamino)-7-oxo-7-(...) Show SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C33H38N2O5/c1-5-39-30(37)24-22-28(34-31(38)40-32(2,3)4)21-23-29(36)35-33(25-15-9-6-10-16-25,26-17-11-7-12-18-26)27-19-13-8-14-20-27/h6-20,22,24,28H,5,21,23H2,1-4H3,(H,34,38)(H,35,36)/b24-22+/t28-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50175214 ((2R,3R)-diethyl 1-((2S)-3-(azetidin-1-yl)-2-(tert-...) Show SMILES CCOC(=O)[C@H]1[C@@H](N1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C(C)C)N1CCC1)C(=O)OCC Show InChI InChI=1S/C22H37N3O7/c1-8-30-19(27)16-17(20(28)31-9-2)25(16)18(26)14(23-21(29)32-22(5,6)7)15(13(3)4)24-11-10-12-24/h13-17H,8-12H2,1-7H3,(H,23,29)/t14-,15?,16+,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Würzburg Curated by ChEMBL					Assay Description Inhibitory activity against cathepsin L				Bioorg Med Chem Lett 15: 5365-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.012 BindingDB Entry DOI: 10.7270/Q2XP74HX
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314132 ((2S,5S,8S,11S,E)-1-Benzyl 16-ethyl 11-(3-amino-3-o...) Show SMILES CCOC(=O)\C=C\CN[C@@H](CCC(N)=O)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C34H51N5O8/c1-5-46-28(41)17-12-20-36-26(18-19-27(35)40)31(42)39-30(25-15-10-7-11-16-25)33(44)38-29(22(2)3)32(43)37-23(4)34(45)47-21-24-13-8-6-9-14-24/h6,8-9,12-14,17,22-23,25-26,29-30,36H,5,7,10-11,15-16,18-21H2,1-4H3,(H2,35,40)(H,37,43)(H,38,44)(H,39,42)/b17-12+/t23-,26-,29-,30-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50175213 ((2S,3S)-dibenzyl 1-((S)-2-(tert-butoxycarbonyl)-2-...) Show SMILES CC(C)(C)OC(=O)N[C@@H](N1CCCCC1)C(=O)N1[C@@H]([C@H]1C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C30H37N3O7/c1-30(2,3)40-29(37)31-25(32-17-11-6-12-18-32)26(34)33-23(27(35)38-19-21-13-7-4-8-14-21)24(33)28(36)39-20-22-15-9-5-10-16-22/h4-5,7-10,13-16,23-25H,6,11-12,17-20H2,1-3H3,(H,31,37)/t23-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Würzburg Curated by ChEMBL					Assay Description Inhibitory activity against cathepsin L				Bioorg Med Chem Lett 15: 5365-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.012 BindingDB Entry DOI: 10.7270/Q2XP74HX
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50314129 ((S,E)-3-((S)-1-Benzyloxycarbonyl-2-phenylethylcarb...) Show SMILES CCOC(=O)\C=C\C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C22H23NO5/c1-2-27-21(25)14-13-20(24)23-19(15-17-9-5-3-6-10-17)22(26)28-16-18-11-7-4-8-12-18/h3-14,19H,2,15-16H2,1H3,(H,23,24)/b14-13+/t19-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay				J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50346543 (CHEMBL1797750) Show SMILES Cc1ccc(cc1)C1CC(=O)Nc2ccc3cc(C)ccc3c12 Show InChI InChI=1S/C21H19NO/c1-13-3-6-15(7-4-13)18-12-20(23)22-19-10-8-16-11-14(2)5-9-17(16)21(18)19/h3-11,18H,12H2,1-2H3,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of SIRT1				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM3175 (3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C25H23N5O2S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346550 (CHEMBL270110) Show SMILES Cc1ccc(cc1)[C@H]1CC(=O)Oc2ccc3cc(C)ccc3c12 Show InChI InChI=1S/C21H18O2/c1-13-3-6-15(7-4-13)18-12-20(22)23-19-10-8-16-11-14(2)5-9-17(16)21(18)19/h3-11,18H,12H2,1-2H3/t18-/m1/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of SIRT2				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM3175 (3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C25H23N5O2S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Homo sapiens (Human))	BDBM3175 (3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C25H23N5O2S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human C-terminally His6-tagged Sirt3 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346546 (CHEMBL1797926) Show SMILES [NH3+]CCn1c2ccc(cc2[nH]c1=S)[N+]([O-])=O Show InChI InChI=1S/C9H10N4O2S/c10-3-4-12-8-2-1-6(13(14)15)5-7(8)11-9(12)16/h1-2,5H,3-4,10H2,(H,11,16)/p+1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50346546 (CHEMBL1797926) Show SMILES [NH3+]CCn1c2ccc(cc2[nH]c1=S)[N+]([O-])=O Show InChI InChI=1S/C9H10N4O2S/c10-3-4-12-8-2-1-6(13(14)15)5-7(8)11-9(12)16/h1-2,5H,3-4,10H2,(H,11,16)/p+1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM74978 (1,3-dihydrobenzo[e]benzimidazole-2-thione | CHEMBL...) Show SMILES S=c1[nH]c2ccc3ccccc3c2[nH]1 Show InChI InChI=1S/C11H6N2S/c14-11-12-9-6-5-7-3-1-2-4-8(7)10(9)13-11/h1-6H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM74978 (1,3-dihydrobenzo[e]benzimidazole-2-thione | CHEMBL...) Show SMILES S=c1[nH]c2ccc3ccccc3c2[nH]1 Show InChI InChI=1S/C11H6N2S/c14-11-12-9-6-5-7-3-1-2-4-8(7)10(9)13-11/h1-6H	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521373 (CHEMBL4573866) Show SMILES Nc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-12-5-1-10(2-6-12)14-9-19(18-17-14)13-7-3-11(4-8-13)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346547 (CHEMBL1797919) Show SMILES [O-][N+](=O)c1cc2[nH]c(=O)[nH]c2c2ccccc12 Show InChI InChI=1S/C11H7N3O3/c15-11-12-8-5-9(14(16)17)6-3-1-2-4-7(6)10(8)13-11/h1-5H,(H2,12,13,15)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521373 (CHEMBL4573866) Show SMILES Nc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-12-5-1-10(2-6-12)14-9-19(18-17-14)13-7-3-11(4-8-13)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346545 (CHEMBL1797923) Show SMILES COc1ccc2[nH]c(=S)[nH]c2n1 Show InChI InChI=1S/C7H7N3OS/c1-11-5-3-2-4-6(9-5)10-7(12)8-4/h2-3H,1H3,(H2,8,9,10,12)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521371 (CHEMBL4569451) Show SMILES OC(=O)c1ccc(cc1)-c1cn(nn1)-c1cccnc1 Show InChI InChI=1S/C14H10N4O2/c19-14(20)11-5-3-10(4-6-11)13-9-18(17-16-13)12-2-1-7-15-8-12/h1-9H,(H,19,20)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521372 (CHEMBL4468809) Show SMILES Nc1ccccc1-n1cc(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-12-3-1-2-4-14(12)19-9-13(17-18-19)10-5-7-11(8-6-10)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521371 (CHEMBL4569451) Show SMILES OC(=O)c1ccc(cc1)-c1cn(nn1)-c1cccnc1 Show InChI InChI=1S/C14H10N4O2/c19-14(20)11-5-3-10(4-6-11)13-9-18(17-16-13)12-2-1-7-15-8-12/h1-9H,(H,19,20)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521373 (CHEMBL4573866) Show SMILES Nc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-12-5-1-10(2-6-12)14-9-19(18-17-14)13-7-3-11(4-8-13)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521369 (CHEMBL4439456) Show SMILES Nc1ccc(cc1)-n1cc(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-12-5-7-13(8-6-12)19-9-14(17-18-19)10-1-3-11(4-2-10)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521371 (CHEMBL4569451) Show SMILES OC(=O)c1ccc(cc1)-c1cn(nn1)-c1cccnc1 Show InChI InChI=1S/C14H10N4O2/c19-14(20)11-5-3-10(4-6-11)13-9-18(17-16-13)12-2-1-7-15-8-12/h1-9H,(H,19,20)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50346545 (CHEMBL1797923) Show SMILES COc1ccc2[nH]c(=S)[nH]c2n1 Show InChI InChI=1S/C7H7N3OS/c1-11-5-3-2-4-6(9-5)10-7(12)8-4/h2-3H,1H3,(H2,8,9,10,12)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521370 (CHEMBL4468972) Show SMILES Nc1ccccc1-c1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-13-4-2-1-3-12(13)14-9-19(18-17-14)11-7-5-10(6-8-11)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521372 (CHEMBL4468809) Show SMILES Nc1ccccc1-n1cc(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-12-3-1-2-4-14(12)19-9-13(17-18-19)10-5-7-11(8-6-10)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521372 (CHEMBL4468809) Show SMILES Nc1ccccc1-n1cc(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-12-3-1-2-4-14(12)19-9-13(17-18-19)10-5-7-11(8-6-10)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521370 (CHEMBL4468972) Show SMILES Nc1ccccc1-c1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-13-4-2-1-3-12(13)14-9-19(18-17-14)11-7-5-10(6-8-11)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346548 (CHEMBL1797922) Show SMILES Clc1ccc2[nH]c(=S)[nH]c2n1 Show InChI InChI=1S/C6H4ClN3S/c7-4-2-1-3-5(9-4)10-6(11)8-3/h1-2H,(H2,8,9,10,11)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521382 (CHEMBL4548393) Show SMILES OCc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H13N3O3/c20-10-11-1-3-12(4-2-11)15-9-19(18-17-15)14-7-5-13(6-8-14)16(21)22/h1-9,20H,10H2,(H,21,22)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521370 (CHEMBL4468972) Show SMILES Nc1ccccc1-c1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H12N4O2/c16-13-4-2-1-3-12(13)14-9-19(18-17-14)11-7-5-10(6-8-11)15(20)21/h1-9H,16H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50346544 (CHEMBL1797920) Show SMILES OC(=O)c1ccc2[nH]c(=S)[nH]c2c1 Show InChI InChI=1S/C8H6N2O2S/c11-7(12)4-1-2-5-6(3-4)10-8(13)9-5/h1-3H,(H,11,12)(H2,9,10,13)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50328901 (4-(4-(Aminomethyl)-1H-1,2,3-triazol-1-yl)benzoic a...) Show SMILES NCc1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C10H10N4O2/c11-5-8-6-14(13-12-8)9-3-1-7(2-4-9)10(15)16/h1-4,6H,5,11H2,(H,15,16)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346549 (CHEMBL1797925) Show SMILES [O-][N+](=O)c1ccc2n(C3CCCCC3)c(=O)[nH]c2c1 Show InChI InChI=1S/C13H15N3O3/c17-13-14-11-8-10(16(18)19)6-7-12(11)15(13)9-4-2-1-3-5-9/h6-9H,1-5H2,(H,14,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346544 (CHEMBL1797920) Show SMILES OC(=O)c1ccc2[nH]c(=S)[nH]c2c1 Show InChI InChI=1S/C8H6N2O2S/c11-7(12)4-1-2-5-6(3-4)10-8(13)9-5/h1-3H,(H,11,12)(H2,9,10,13)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL					Assay Description Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay				Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521381 (CHEMBL4436463) Show SMILES OC(=O)c1ccc(cc1)-n1cc(nn1)C1(O)CCCC1 Show InChI InChI=1S/C14H15N3O3/c18-13(19)10-3-5-11(6-4-10)17-9-12(15-16-17)14(20)7-1-2-8-14/h3-6,9,20H,1-2,7-8H2,(H,18,19)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521379 (CHEMBL4449651) Show SMILES OC(=O)c1ccc(cc1)-c1cn(nn1)-c1ccc(O)cc1 Show InChI InChI=1S/C15H11N3O3/c19-13-7-5-12(6-8-13)18-9-14(16-17-18)10-1-3-11(4-2-10)15(20)21/h1-9,19H,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair
ORF 73 (Human herpesvirus 8)	BDBM50521383 (CHEMBL4559370) Show SMILES OCc1cn(nn1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C10H9N3O3/c14-6-8-5-13(12-11-8)9-3-1-7(2-4-9)10(15)16/h1-5,14H,6H2,(H,15,16)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...				J Med Chem 62: 3924-3939 (2019) Article DOI: 10.1021/acs.jmedchem.8b01827 BindingDB Entry DOI: 10.7270/Q2H135D6
					More data for this Ligand-Target Pair

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